메뉴 건너뛰기




Volumn 15, Issue 6, 2014, Pages 833-843

Evaluation of clinical and genetic indicators for the early response to intravitreal ranibizumab in exudative age-related macular degeneration

Author keywords

3 months results; age related macular degeneration; age related maculopathy susceptibility 2; anatomical outcome; complement factor H; ranibizumab; single nucleotide polymorphism

Indexed keywords

RANIBIZUMAB; ARMS2 PROTEIN, HUMAN; COMPLEMENT FACTOR H; MONOCLONAL ANTIBODY; PROTEIN;

EID: 84901984256     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/pgs.14.51     Document Type: Article
Times cited : (15)

References (34)
  • 2
    • 34249101587 scopus 로고    scopus 로고
    • Age-related macular degeneration and recent developments: New hope for old eyes? Postgrad
    • Morris B, Imrie F, Armbrecht AM, Dhillon B. Age-related macular degeneration and recent developments: new hope for old eyes? Postgrad. Med. J. 83(979), 301-307 (2007).
    • (2007) Med. J. , vol.83 , Issue.979 , pp. 301-307
    • Morris, B.1    Imrie, F.2    Armbrecht, A.M.3    Dhillon, B.4
  • 3
    • 74549137478 scopus 로고    scopus 로고
    • Ranibizumab (Lucentis) in neovascular age-related macular degeneration: Evidence from clinical trials
    • Mitchell P, Korobelnik JF, Lanzetta P et al. Ranibizumab (Lucentis) in neovascular age-related macular degeneration: evidence from clinical trials. Br. J. Ophthalmol. 94(1), 2-13 (2010).
    • (2010) Br. J. Ophthalmol. , vol.94 , Issue.1 , pp. 2-13
    • Mitchell, P.1    Korobelnik, J.F.2    Lanzetta, P.3
  • 4
    • 33947403618 scopus 로고    scopus 로고
    • An optical coherence tomography-guided, variable dosing regimen with intravitreal ranibizumab (Lucentis) for neovascular age-related macular degeneration
    • Fung AE, Lalwani GA, Rosenfeld PJ et al. An optical coherence tomography-guided, variable dosing regimen with intravitreal ranibizumab (Lucentis) for neovascular age-related macular degeneration. Am. J. Ophthalmol. 143(4), 566-583 (2007).
    • (2007) Am. J. Ophthalmol. , vol.143 , Issue.4 , pp. 566-583
    • Fung, A.E.1    Lalwani, G.A.2    Rosenfeld, P.J.3
  • 5
    • 79956218863 scopus 로고    scopus 로고
    • Ranibizumab and bevacizumab for neovascular age-related macular degeneration
    • CATT Research Group
    • CATT Research Group, Martin DF, Maguire MG et al. Ranibizumab and bevacizumab for neovascular age-related macular degeneration. N. Engl. J. Med. 364(20), 1897-1908 (2011).
    • (2011) N. Engl. J. Med. , vol.364 , Issue.20 , pp. 1897-1908
    • Martin, D.F.1    Maguire, M.G.2
  • 6
    • 84880587327 scopus 로고    scopus 로고
    • Initial non-responders to ranibizumab in the treatment of age-related macular degeneration (AMD)
    • Otsuji T, Nagai Y, Sho K et al. Initial non-responders to ranibizumab in the treatment of age-related macular degeneration (AMD). Clin. Ophthalmol. 7, 1487-1490 (2013).
    • (2013) Clin. Ophthalmol. , vol.7 , pp. 1487-1490
    • Otsuji, T.1    Nagai, Y.2    Sho, K.3
  • 7
    • 84864328535 scopus 로고    scopus 로고
    • Impact of loading phase, initial response and CFH genotype on the long-term outcome of treatment for neovascular age-related macular degeneration
    • Menghini M, Kloeckener-Gruissem B, Fleischhauer J et al. Impact of loading phase, initial response and CFH genotype on the long-term outcome of treatment for neovascular age-related macular degeneration. PLoS ONE 7(7), e42014 (2012).
    • (2012) PLoS ONE , vol.7 , Issue.7
    • Menghini, M.1    Kloeckener-Gruissem, B.2    Fleischhauer, J.3
  • 8
    • 84872072339 scopus 로고    scopus 로고
    • Anatomical measures as predictors of visual outcomes in ranibizumab-treated eyes with neovascular age-related macular degeneration
    • Pier Study Group
    • Brown DM, Tuomi L, Shapiro H; Pier Study Group. Anatomical measures as predictors of visual outcomes in ranibizumab-treated eyes with neovascular age-related macular degeneration. Retina 33(1), 23-34 (2013).
    • (2013) Retina , vol.33 , Issue.1 , pp. 23-34
    • Brown, D.M.1    Tuomi, L.2    Shapiro, H.3
  • 9
    • 84856776005 scopus 로고    scopus 로고
    • Early responses to intravitreal ranibizumab in typical neovascular age-related macular degeneration and polypoidal choroidal vasculopathy
    • Matsumiya W, Honda S, Bessho H, Kusuhara S, Tsukahara Y, Negi A. Early responses to intravitreal ranibizumab in typical neovascular age-related macular degeneration and polypoidal choroidal vasculopathy. J. Ophthalmol. 2011, 742020 (2011).
    • (2011) J. Ophthalmol. , vol.2011 , pp. 742020
    • Matsumiya, W.1    Honda, S.2    Bessho, H.3    Kusuhara, S.4    Tsukahara, Y.5    Negi, A.6
  • 10
    • 84875688194 scopus 로고    scopus 로고
    • Effectiveness of intravitreal ranibizumab in exudative age-related macular degeneration (AMD): Comparison between typical neovascular AMD and polypoidal choroidal vasculopathy over a 1 year follow-up
    • Matsumiya W, Honda S, Kusuhara S, Tsukahara Y, Negi A. Effectiveness of intravitreal ranibizumab in exudative age-related macular degeneration (AMD): comparison between typical neovascular AMD and polypoidal choroidal vasculopathy over a 1 year follow-up. BMC Ophthalmol. 13, 10 (2013).
    • (2013) BMC Ophthalmol. , vol.13 , pp. 10
    • Matsumiya, W.1    Honda, S.2    Kusuhara, S.3    Tsukahara, Y.4    Negi, A.5
  • 11
    • 34547454184 scopus 로고    scopus 로고
    • Guidance for the treatment of neovascular age-related macular degeneration
    • Schmidt-Erfurth UM, Richard G, Augustin A et al. Guidance for the treatment of neovascular age-related macular degeneration. Acta Ophthalmol. Scand. 85(5), 486-494 (2007).
    • (2007) Acta Ophthalmol. Scand. , vol.85 , Issue.5 , pp. 486-494
    • Schmidt-Erfurth, U.M.1    Richard, G.2    Augustin, A.3
  • 12
    • 52949129894 scopus 로고    scopus 로고
    • Anti-vascular endothelial growth factor pharmacotherapy for age-related macular degeneration: A report by the American academy of ophthalmology
    • Ip MS, Scott IU, Brown GC et al. Anti-vascular endothelial growth factor pharmacotherapy for age-related macular degeneration: a report by the American academy of ophthalmology. Ophthalmology 115(10), 1837-1846 (2008).
    • (2008) Ophthalmology , vol.115 , Issue.10 , pp. 1837-1846
    • Ip, M.S.1    Scott, I.U.2    Brown, G.C.3
  • 13
    • 33749445317 scopus 로고    scopus 로고
    • Ranibizumab for neovascular age-related macular degeneration
    • Rosenfeld PJ, Brown DM, Heier JS et al. Ranibizumab for neovascular age-related macular degeneration. N. Engl. J. Med. 355(14), 1419-1431 (2006).
    • (2006) N. Engl. J. Med. , vol.355 , Issue.14 , pp. 1419-1431
    • Rosenfeld, P.J.1    Brown, D.M.2    Heier, J.S.3
  • 14
    • 57949094834 scopus 로고    scopus 로고
    • Ranibizumab versus verteporfin photodynamic therapy for neovascular age-related macular degeneration: Two-year results of the ANCHOR study
    • Brown DM, Michels M, Kaiser PK et al. Ranibizumab versus verteporfin photodynamic therapy for neovascular age-related macular degeneration: two-year results of the ANCHOR study. Ophthalmology 116(1), 57-65 (2009).
    • (2009) Ophthalmology , vol.116 , Issue.1 , pp. 57-65
    • Brown, D.M.1    Michels, M.2    Kaiser, P.K.3
  • 15
    • 81555219239 scopus 로고    scopus 로고
    • Outcomes following three-line vision loss during treatment of neovascular age-related macular degeneration: Subgroup analyses from MARINA and ANCHOR
    • Wolf S, Holz FG, Korobelnik JF et al. Outcomes following three-line vision loss during treatment of neovascular age-related macular degeneration: subgroup analyses from MARINA and ANCHOR. Br. J. Ophthalmol. 95(12), 1713-1718 (2011).
    • (2011) Br. J. Ophthalmol. , vol.95 , Issue.12 , pp. 1713-1718
    • Wolf, S.1    Holz, F.G.2    Korobelnik, J.F.3
  • 16
    • 84865049405 scopus 로고    scopus 로고
    • Association between variant Y402H in age-related macular degeneration (AMD) susceptibility gene CFH and treatment response of AMD: A meta-analysis
    • Chen H, Yu KD, Xu GZ. Association between variant Y402H in age-related macular degeneration (AMD) susceptibility gene CFH and treatment response of AMD: a meta-analysis. PLoS ONE 7(8), e42464 (2012).
    • (2012) PLoS ONE , vol.7 , Issue.8
    • Chen, H.1    Yu, K.D.2    Xu, G.Z.3
  • 17
    • 84856134918 scopus 로고    scopus 로고
    • The influence of genetics on response to treatment with ranibizumab (Lucentis) for age-related macular degeneration: The Lucentis Genotype Study (an American Ophthalmological Society thesis)
    • Francis PJ. The influence of genetics on response to treatment with ranibizumab (Lucentis) for age-related macular degeneration: the Lucentis Genotype Study (an American Ophthalmological Society thesis). Trans. Am. Ophthalmol. Soc. 109, 115-156 (2011).
    • (2011) Trans. Am. Ophthalmol. Soc. , vol.109 , pp. 115-156
    • Francis, P.J.1
  • 18
    • 84855170104 scopus 로고    scopus 로고
    • Association between high-risk disease loci and response to anti-vascular endothelial growth factor treatment for wet age-related macular degeneration
    • Orlin A, Hadley D, Chang W et al. Association between high-risk disease loci and response to anti-vascular endothelial growth factor treatment for wet age-related macular degeneration. Retina 32(1), 4-9 (2012).
    • (2012) Retina , vol.32 , Issue.1 , pp. 4-9
    • Orlin, A.1    Hadley, D.2    Chang, W.3
  • 19
    • 80051763854 scopus 로고    scopus 로고
    • Genetic association with response to intravitreal ranibizumab in patients with neovascular AMD
    • Kloeckener-Gruissem B, Barthelmes D, Labs S et al. Genetic association with response to intravitreal ranibizumab in patients with neovascular AMD. Invest. Ophthalmol. Vis. Sci. 52(7), 4694-4702 (2011).
    • (2011) Invest. Ophthalmol. Vis. Sci. , vol.52 , Issue.7 , pp. 4694-4702
    • Kloeckener-Gruissem, B.1    Barthelmes, D.2    Labs, S.3
  • 20
    • 84862760298 scopus 로고    scopus 로고
    • Factors associated with the response of age-related macular degeneration to intravitreal ranibizumab treatment
    • Yamashiro K, Tomita K, Tsujikawa A et al. Factors associated with the response of age-related macular degeneration to intravitreal ranibizumab treatment. Am. J. Ophthalmol. 154(1), 125-136 (2012).
    • (2012) Am. J. Ophthalmol. , vol.154 , Issue.1 , pp. 125-136
    • Yamashiro, K.1    Tomita, K.2    Tsujikawa, A.3
  • 21
    • 84856059368 scopus 로고    scopus 로고
    • CFH, VEGF and HTRA1 promoter genotype may influence the response to intravitreal ranibizumab therapy for neovascular age-related macular degeneration
    • McKibbin M, Ali M, Bansal S et al. CFH, VEGF and HTRA1 promoter genotype may influence the response to intravitreal ranibizumab therapy for neovascular age-related macular degeneration. Br. J. Ophthalmol. 96(2), 208-212 (2012).
    • (2012) Br. J. Ophthalmol. , vol.96 , Issue.2 , pp. 208-212
    • McKibbin, M.1    Ali, M.2    Bansal, S.3
  • 22
    • 66149089631 scopus 로고    scopus 로고
    • Pharmacogenetics of complement factor H (Y402H) and treatment of exudative age-related macular degeneration with ranibizumab
    • Lee AY, Raya AK, Kymes SM, Shiels A, Brantley MA. Pharmacogenetics of complement factor H (Y402H) and treatment of exudative age-related macular degeneration with ranibizumab. Br. J. Ophthalmol. 93(5), 610-613 (2009).
    • (2009) Br. J. Ophthalmol. , vol.93 , Issue.5 , pp. 610-613
    • Lee, A.Y.1    Raya, A.K.2    Kymes, S.M.3    Shiels, A.4    Brantley, M.A.5
  • 23
    • 84864396563 scopus 로고    scopus 로고
    • Pharmacogenetics of antiangiogenic and antineovascular therapies of age-related macular degeneration
    • Agosta E, Lazzeri S, Orlandi P et al. Pharmacogenetics of antiangiogenic and antineovascular therapies of age-related macular degeneration. Pharmacogenomics 13(9), 1037-1053 (2012).
    • (2012) Pharmacogenomics , vol.13 , Issue.9 , pp. 1037-1053
    • Agosta, E.1    Lazzeri, S.2    Orlandi, P.3
  • 24
    • 84868194934 scopus 로고    scopus 로고
    • Cumulative effect of risk alleles in CFH, ARMS2, and VEGFA on the response to ranibizumab treatment in age-related macular degeneration
    • Smailhodzic D, Muether PS, Chen J et al. Cumulative effect of risk alleles in CFH, ARMS2, and VEGFA on the response to ranibizumab treatment in age-related macular degeneration. Ophthalmology 119(11), 2304-2311 (2012).
    • (2012) Ophthalmology , vol.119 , Issue.11 , pp. 2304-2311
    • Smailhodzic, D.1    Muether, P.S.2    Chen, J.3
  • 25
    • 84872022283 scopus 로고    scopus 로고
    • Variants in the VEGFA gene and treatment outcome after anti-VEGF treatment for neovascular age-related macular degeneration
    • Abedi F, Wickremasinghe S, Richardson AJ et al. Variants in the VEGFA gene and treatment outcome after anti-VEGF treatment for neovascular age-related macular degeneration. Ophthalmology 120(1), 115-121 (2013).
    • (2013) Ophthalmology , vol.120 , Issue.1 , pp. 115-121
    • Abedi, F.1    Wickremasinghe, S.2    Richardson, A.J.3
  • 26
    • 84875433957 scopus 로고    scopus 로고
    • Pharmacogenetic association with early response to intravitreal ranibizumab for age-related macular degeneration in a Korean population
    • Chang W, Noh DH, Sagong M, Kim IT. Pharmacogenetic association with early response to intravitreal ranibizumab for age-related macular degeneration in a Korean population. Mol. Vis. 19, 702-709 (2013).
    • (2013) Mol. Vis. , vol.19 , pp. 702-709
    • Chang, W.1    Noh, D.H.2    Sagong, M.3    Kim, I.T.4
  • 27
    • 84875990285 scopus 로고    scopus 로고
    • VEGF-A polymorphisms predict short-term functional response to intravitreal ranibizumab in exudative age-related macular degeneration
    • Lazzeri S, Figus M, Orlandi P et al. VEGF-A polymorphisms predict short-term functional response to intravitreal ranibizumab in exudative age-related macular degeneration. Pharmacogenomics 14(6), 623-630 (2013).
    • (2013) Pharmacogenomics , vol.14 , Issue.6 , pp. 623-630
    • Lazzeri, S.1    Figus, M.2    Orlandi, P.3
  • 28
    • 84865282678 scopus 로고    scopus 로고
    • Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids
    • Shaw PX, Zhang L, Zhang M et al. Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids. Proc. Natl Acad. Sci. USA 109(34), 13757-13762 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , Issue.34 , pp. 13757-13762
    • Shaw, P.X.1    Zhang, L.2    Zhang, M.3
  • 29
    • 79551507173 scopus 로고    scopus 로고
    • Complement factor H Y402H variant and risk of age-related macular degeneration in Asians: A systematic review and meta-analysis
    • Kondo N, Bessho H, Honda S, Negi A. Complement factor H Y402H variant and risk of age-related macular degeneration in Asians: a systematic review and meta-analysis. Ophthalmology 118(2), 339-344 (2011).
    • (2011) Ophthalmology , vol.118 , Issue.2 , pp. 339-344
    • Kondo, N.1    Bessho, H.2    Honda, S.3    Negi, A.4
  • 30
    • 69449090499 scopus 로고    scopus 로고
    • The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity
    • Tortajada A, Montes T, Martínez-Barricarte R, Morgan BP, Harris CL, de Córdoba SR. The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity. Hum. Mol. Genet. 18(18), 3452-3461 (2009).
    • (2009) Hum. Mol. Genet. , vol.18 , Issue.18 , pp. 3452-3461
    • Tortajada, A.1    Montes, T.2    Martínez-Barricarte, R.3    Morgan, B.P.4    Harris, C.L.5    De Córdoba, S.R.6
  • 31
    • 23944468114 scopus 로고    scopus 로고
    • Membranoproliferative glomerulonephritis type II (dense deposit disease): An update
    • Appel GB, Cook HT, Hageman G et al. Membranoproliferative glomerulonephritis type II (dense deposit disease): an update. J. Am. Soc. Nephrol. 16(5), 1392-1403 (2005).
    • (2005) J. Am. Soc. Nephrol. , vol.16 , Issue.5 , pp. 1392-1403
    • Appel, G.B.1    Cook, H.T.2    Hageman, G.3
  • 32
    • 33751243644 scopus 로고    scopus 로고
    • Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid
    • Johnson PT, Betts KE, Radeke MJ, Hageman GS, Anderson DH, Johnson LV. Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid. Proc. Natl Acad. Sci. USA 103(46), 17456-17461 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , Issue.46 , pp. 17456-17461
    • Johnson, P.T.1    Betts, K.E.2    Radeke, M.J.3    Hageman, G.S.4    Anderson, D.H.5    Johnson, L.V.6
  • 33
    • 79955596897 scopus 로고    scopus 로고
    • The association of ARMS2 polymorphisms with phenotype in typical neovascular age-related macular degeneration and polypoidal choroidal vasculopathy
    • Bessho H, Honda S, Kondo N, Negi A. The association of ARMS2 polymorphisms with phenotype in typical neovascular age-related macular degeneration and polypoidal choroidal vasculopathy. Mol. Vis. 17, 977-982 (2011).
    • (2011) Mol. Vis. , vol.17 , pp. 977-982
    • Bessho, H.1    Honda, S.2    Kondo, N.3    Negi, A.4
  • 34
    • 36549016602 scopus 로고    scopus 로고
    • Association of complement factor H and LOC387715 genotypes with response of exudative age-related macular degeneration to intravitreal bevacizumab
    • Brantley MA, Fang AM, King JM, Tewari A, Kymes SM, Shiels A. Association of complement factor H and LOC387715 genotypes with response of exudative age-related macular degeneration to intravitreal bevacizumab. Ophthalmology 114(12), 2168-2173 (2007).
    • (2007) Ophthalmology , vol.114 , Issue.12 , pp. 2168-2173
    • Brantley, M.A.1    Fang, A.M.2    King, J.M.3    Tewari, A.4    Kymes, S.M.5    Shiels, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.