In vitro passage selects for Chlamydia muridarum with enhanced infectivity in cultured cells but attenuated pathogenicity in mouse upper genital tract

Infection and Immunity

Volumn 83, Issue 5, 2015, Pages 1881-1892

  Chen, Chaoqun ^a,b   Zhou, Zhou ^a,b   Conrad, Turner ^a   Yang, Zhangsheng ^a   Dai, Jin ^a   Li, Zhongyu ^b   Wu, Yimou ^b   Zhong, Guangming ^a  

^a University of Texas Health Science Center   (United States)

^b UNIVERSITY OF SOUTH CHINA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CXCL9 CHEMOKINE; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 15; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; PROTEIN VARIANT; VIRULENCE FACTOR; BACTERIAL DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; CHLAMYDIA MURIDARUM; CHLAMYDIASIS; CONTROLLED STUDY; FEMALE; GENE DELETION; GENE INSERTION; GENITAL TRACT INFECTION; GENOTYPE; HELA CELL LINE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; INCIDENCE; INDEL MUTATION; MOUSE; NEXT GENERATION SEQUENCING; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PATHOGENICITY; PHENOTYPE; PRIORITY JOURNAL; TH17 CELL; TISSUE CULTURE; ANIMAL; BACTERIUM ADHERENCE; C3H MOUSE; CHEMISTRY; GENETIC SELECTION; GENETICS; HIGH THROUGHPUT SEQUENCING; MICROBIOLOGY; PATHOLOGY; PHYSIOLOGY; VIRULENCE; VIRUS CULTURE;

ANIMALS; BACTERIAL ADHESION; CHLAMYDIA INFECTIONS; CHLAMYDIA MURIDARUM; DNA, BACTERIAL; FEMALE; HELA CELLS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MICE, INBRED C3H; REPRODUCTIVE TRACT INFECTIONS; SELECTION, GENETIC; SERIAL PASSAGE; VIRULENCE;

EID: 84928183772     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.03158-14     Document Type: Article

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