Enhanced upper genital tract pathologies by blocking Tim-3 and PD-L1 signaling pathways in mice intravaginally infected with Chlamydia muridarum

BMC Infectious Diseases

Volumn 11, Issue , 2011, Pages

  Peng, Bo ^a,b   Lu, Chunxue ^a,c   Tang, Lingli ^a   Yeh, I Tien ^a   He, Zhimin ^b   Wu, Yimou ^c   Zhong, Guangming ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b Central South University   (China)

^c UNIVERSITY OF SOUTH CHINA   (China)

Author keywords

Chlamydia muridarum; Oviduct pathology; Pd l1 signaling pathways; Tim 3

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN G; MEMBRANE PROTEIN; PROGRAMMED DEATH 1 LIGAND 1; PROTEIN ANTIBODY; PROTEIN TIM 3; UNCLASSIFIED DRUG; CD274 PROTEIN, MOUSE; HAVCR2 PROTEIN, MOUSE; VIRUS RECEPTOR;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL SHEDDING; CELLULAR IMMUNITY; CHLAMYDIA; CHLAMYDIASIS; CONTROLLED STUDY; CYTOKINE RESPONSE; DISEASE SEVERITY; FEMALE; FEMALE GENITAL TRACT INFLAMMATION; HUMORAL IMMUNITY; HYDROSALPINX; MOUSE; NONHUMAN; OVIDUCT; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; PROTEIN TARGETING; SCORING SYSTEM; SIGNAL TRANSDUCTION; UTERUS HORN; VAGINITIS; ANIMAL; BAGG ALBINO MOUSE; DRUG ANTAGONISM; FEMALE GENITAL SYSTEM; GENITAL TRACT INFECTION; IMMUNOLOGY; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY;

ANIMALS; ANTIGENS, CD274; BACTERIAL SHEDDING; CHLAMYDIA INFECTIONS; CHLAMYDIA MURIDARUM; FEMALE; GENITALIA, FEMALE; MICE; MICE, INBRED BALB C; RECEPTORS, VIRUS; REPRODUCTIVE TRACT INFECTIONS; SIGNAL TRANSDUCTION;

EID: 83355164003     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-11-347     Document Type: Article

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