Association of in vitro fertilization with global and IGF2/H19 methylation variation in newborn twins

Journal of Developmental Origins of Health and Disease

Volumn 6, Issue 2, 2015, Pages 115-124

  Loke, Y J ^a   Galati, J C ^a   Saffery, R ^a,b   Craig, J M ^a,b  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

DNA methylation; early life environment; in vitro fertilization (IVF); twins

Indexed keywords

H19 LONG NON-CODING RNA; IGF2 PROTEIN, HUMAN; LONG UNTRANSLATED RNA; SOMATOMEDIN B;

ADULT; ADVERSE EFFECTS; DNA METHYLATION; FEMALE; GENETIC EPIGENESIS; GENETICS; HUMAN; IN VITRO FERTILIZATION; MALE; NEWBORN; PREGNANCY; TWINS;

ADULT; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; FERTILIZATION IN VITRO; HUMANS; INFANT, NEWBORN; INSULIN-LIKE GROWTH FACTOR II; MALE; PREGNANCY; RNA, LONG NONCODING; TWINS;

EID: 84928183059     PISSN: 20401744     EISSN: 20401752     Source Type: Journal    
DOI: 10.1017/S2040174415000161     Document Type: Article

References (55)

1. Bird A. Perceptions of epigenetics. Nature. 2007; 447, 396-398.
2. Smith ZD, Chan MM, Mikkelsen TS, et al. A unique regulatory phase of DNA methylation in the early mammalian embryo. Nature . 2012; 484, 339-344.
3. Guo H, Zhu P, Yan L, et al. The DNA methylation landscape of human early embryos. Nature. 2014; 511, 606-610.
4. Chason RJ, Csokmay J, Segars JH, et al. Environmental and epigenetic effects upon preimplantation embryo metabolism and development. Trends Endocrinol Metab. 2011; 22, 412-420.
5. Katari S, Turan N, Bibikova M, et al. DNA methylation and gene expression differences in children conceived in vitro or in vivo. Hum Mol Genet . 2009; 18, 3769-3778.
6. Tierling S, Souren NY, Gries J, et al. Assisted reproductive technologies do not enhance the variability of DNA methylation imprints in human. J Med Genet. 2010; 47, 371-376.
7. Zheng HY, Tang Y, Niu J, et al. Aberrant DNA methylation of imprinted loci in human spontaneous abortions after assisted reproduction techniques and natural conception. Hum Reprod. 2013; 28, 265-273.
8. Turan N, Katari S, Gerson LF, et al. Inter- and intra-individual variation in allele-specific DNA methylation and gene expression in children conceived using assisted reproductive technology. PLoS Genet. 2010; 6, e1001033.
9. Nelissen EC, Dumoulin JC, Daunay A, et al. Placentas from pregnancies conceived by IVF/ICSI have a reduced DNA methylation level at the H19 and MEST differentially methylated regions. Hum Reprod. 2013; 28, 1117-1126.
10. Kobayashi H, Hiura H, John RM, et al. DNA methylation errors at imprinted loci after assisted conception originate in the parental sperm. Eur J Hum Genet. 2009; 17, 1582-1591.
11. Breton CV, Byun HM, Wenten M, et al. Prenatal tobacco smoke exposure affects global and gene-specific DNA methylation. Am J Resp Crit Care. 2009; 180, 462-467.
12. Terry MB, Ferris JS, Pilsner R, et al. Genomic DNA methylation among women in a multiethnic New York City birth cohort. Cancer Epidem Biomar. 2008; 17, 2306-2310.
13. Wilhelm-Benartzi CS, Houseman EA, Maccani MA, et al. In utero exposures, infant growth, and DNA methylation of repetitive elements and developmentally related genes in human placenta. Environ Health Persp. 2012; 120, 296-302.
14. Loke YJ, Galati JC, Morley R, et al. Association of maternal and nutrient supply line factors with DNA methylation at the imprinted IGF2/H19 locus in multiple tissues of newborn twins. Epigenetics. 2013; 8, 1069-1079.
15. Hoyo C, Murtha AP, Schildkraut JM, et al. Methylation variation at IGF2 differentially methylated regions and maternal folic acid use before and during pregnancy. Epigenetics. 2011; 6, 928-936.
16. Steegers-Theunissen RP, Obermann-Borst SA, Kremer D, et al. Periconceptional maternal folic acid use of 400 microg per day is related to increased methylation of the IGF2 gene in the very young child. PLoS One. 2009; 4, e7845.
17. Haycock PC, Ramsay M. Exposure of mouse embryos to ethanol during preimplantation development: effect on DNA methylation in the h19 imprinting control region. Biol Reprod. 2009; 81, 618-627.
18. Chen J, Li Q, Rialdi A, et al. Influences of maternal stress during pregnancy on the Epi/genome: comparison of placenta and umbilical cord blood. J Depress Anxiety. 2014; 3, 1-6.
19. Tobi EW, Slagboom PE, van Dongen J, et al. Prenatal famine and genetic variation are independently and additively associated with DNA methylation at regulatory loci within IGF2/H19. PLoS One. 2012; 7, e37933.
20. Tobi EW, Lumey LH, Talens RP, et al. DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific. Hum Mol Genet. 2009; 18, 4046-4053.
21. Heijmans BT, Tobi EW, Stein AD, et al. Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc Natl Acad Sci USA. 2008; 105, 17046-17049.
22. Kulkarni A, Dangat K, Kale A, et al. Effects of altered maternal folic Acid, vitamin b(12) and docosahexaenoic acid on placental global DNA methylation patterns in wistar rats. PLoS One. 2011; 6, e17706.
23. Takimoto H, Hayashi F, Kusama K, et al. Elevated maternal serum folate in the third trimester and reduced fetal growth: a longitudinal study. J Nutr Sci Vitaminol. 2011; 57, 130-137.
24. Cordaux R, Batzer MA. The impact of retrotransposons on human genome evolution. Nat Rev Genet. 2009; 10, 691-703.
25. Murrell A, Heeson S, Reik W. Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops. Nat Genet. 2004; 36, 889-893.
26. Goshen R, Rachmilewitz J, Schneider T, et al . The expression of the H-19 and IGF-2 genes during human embryogenesis and placental development. Mol Reprod Dev. 1993; 34, 374-379.
27. O'Dell SD, Day INM. Molecules in focus insulin-like growth factor II (IGF-II). Int J Biochem Cell B. 1998; 30, 767-771.
28. Szabo PE, Tang SH, Silva FJ, et al. Role of CTCF binding sites in the Igf2/H19 imprinting control region. Mol Cell Biol. 2004; 24, 4791-4800.
29. Fauque P, Jouannet P, Lesaffre C, et al. Assisted reproductive technology affects developmental kinetics, h19 imprinting control region methylation and h19 gene expression in individual mouse embryos. BMC Dev Biol. 2007; 7, 116.
30. Li L, Wang L, Le F, et al. Evaluation of DNA methylation status at differentially methylated regions in IVF-conceived newborn twins. Fertil Steril. 2011; 95, 1975-1979.
31. Saffery R, Morley R, Carlin JB, et al. Cohort profile: the peri/post-natal epigenetic twins study. Int J Epidemiol. 2012; 41, 55-61.
32. Loke YJ, Novakovic B, Ollikainen M, et al. The Peri/Postnatal Epigenetic Twins Study (PETS). Twin Res Hum Genet. 2013; 16, 13-20.
33. Ollikainen M, Smith KR, Joo EJ, et al. DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome. Hum Mol Genet. 2010; 19, 4176-4188.
34. Flotho C, Claus R, Batz C, et al. The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells. Leukemia. 2009; 23, 1019-1028.
35. Bland JM, Altman DG. Multiple significance tests: the Bonferroni method. BMJ. 1995; 310, 170.
36. Whitelaw N, Bhattacharya S, Hoad G, et al. Epigenetic status in the offspring of spontaneous and assisted conception. Hum Reprod . 2014; 29, 1452-1458.
37. Luo Y, Lu X, Xie H. Dynamic methylation during normal development, aging, and tumorigenesis. Biomed Res Int. 2014; 2014, 784706.
38. Kitkumthorn N, Keelawat S, Rattanatanyong P, et al. LINE-1 and Alu methylation patterns in lymph node metastases of head and neck cancers. Asian Pac J Cancer Prev. 2012; 13, 4469-4475.
39. Li J, Huang Q, Zeng F, et al. The prognostic value of global DNA hypomethylation in cancer: a meta-analysis. PLoS One. 2014; 9, e106290.
40. Baccarelli A, Wright RO, Bollati V, et al. Rapid DNA methylation changes after exposure to traffic particles. Am J Respir Crit Care Med . 2009; 179, 572-578.
41. Perng W, Mora-Plazas M, Marin C, et al. A prospective study of LINE-1DNA methylation and development of adiposity in school-age children. PLoS One. 2013; 8, e62587.
42. Baccarelli A, Wright R, Bollati V, et al. Ischemic heart disease and stroke in relation to blood DNA methylation. Epidemiology. 2010; 21, 819-828.
43. Baccarelli A, Tarantini L, Wright RO, et al. Repetitive element DNA methylation and circulating endothelial and inflammation markers in the VA normative aging study. Epigenetics. 2010; 5, 222-228.
44. Pearce MS, McConnell JC, Potter C, et al. Global LINE-1 DNA methylation is associated with blood glycaemic and lipid profiles. Int J Epidemiol. 2012; 41, 210-217.
45. Cash HL, McGarvey ST, Houseman EA, et al. Cardiovascular disease risk factors and DNA methylation at the LINE-1 repeat region in peripheral blood from Samoan Islanders. Epigenetics. 2011; 6, 1257-1264.
46. Zhao J, Goldberg J, Bremner JD, et al. Global DNA methylation is associated with insulin resistance: a monozygotic twin study. Diabetes. 2012; 61, 542-546.
47. Hart R, Norman RJ. The longer-term health outcomes for children born as a result of IVF treatment: Part I - General health outcomes. Hum Reprod Update. 2013; 19, 232-243.
48. Kawano H, Saeki H, Kitao H, et al. Chromosomal instability associated with global DNA hypomethylation is associated with the initiation and progression of esophageal squamous cell carcinoma. Ann Surg Oncol. 2014; 21 (suppl 4), 696-702.
49. Esteller M. Epigenetics in cancer. N Engl J Med. 2008; 358, 1148-1159.
50. Suter CM, Martin DI, Ward RL. Hypomethylation of L1 retrotransposons in colorectal cancer and adjacent normal tissue. Int J Colorectal Dis. 2004; 19, 95-101.
51. Gao XD, Qu JH, Chang XJ, et al. Hypomethylation of long interspersed nuclear element-1 promoter is associated with poor outcomes for curative resected hepatocellular carcinoma. Liver Int . 2014; 34, 136-146.
52. Bell AC, Felsenfeld G. Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene. Nature. 2000; 405, 482-485.
53. Thorvaldsen JL, Duran KL, Bartolomei MS. Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2. Genes Dev. 1998; 12, 3693-3702.
54. Bloise E, Lin W, Liu X, et al. Impaired placental nutrient transport in mice generated by in vitro fertilization. Endocrinology. 2012; 153, 3457-3467.
55. Delle Piane L, Lin W, Liu X, et al. Effect of the method of conception and embryo transfer procedure on mid-gestation placenta and fetal development in an IVF mouse model. Hum Reprod . 2010; 25, 2039-2046.