The Peri/postnatal epigenetic twins study (PETS)

Twin Research and Human Genetics

Volumn 16, Issue 1, 2013, Pages 13-20

  Loke, Yuk Jing ^a   Novakovic, Boris ^a,b   Ollikainen, Miina ^c   Wallace, Euan M ^d   Umstad, Mark P ^b   Permezel, Michael ^b   Morley, Ruth ^a   Ponsonby, Anne Louise ^e   Gordon, Lavinia ^e   Galati, John C ^e   Saffery, Richard ^a,b   Craig, Jeffrey M ^a  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF HELSINKI   (Finland)

^d HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^e MURDOCH CHILDREN'S RESEARCH INSTITUTE   (Australia)

Author keywords

birth; developmental origins; environment; epigenetic; twins

Indexed keywords

ARTICLE; AUSTRALIA; BIRTH WEIGHT; CHEEK; DIET; DIZYGOTIC TWINS; DNA DETERMINATION; DNA METHYLATION; EPIGENETICS; GENE EXPRESSION; GENETIC PREDISPOSITION; GENETIC VARIABILITY; GESTATIONAL AGE; HUMAN; INTRAUTERINE GROWTH RETARDATION; LIFESTYLE; MONOZYGOTIC TWINS; PERINATAL PERIOD; PLACENTA; PREGNANCY; PRIORITY JOURNAL; TWIN DISCORDANCE; TWIN ZYGOSITY; TWINS; UMBILICAL CORD BLOOD;

DIET; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; FETAL GROWTH RETARDATION; GESTATIONAL AGE; HUMANS; INFANT; INFANT, NEWBORN; LIFE STYLE; LONGITUDINAL STUDIES; PREGNANCY; TWINS;

EID: 84873909354     PISSN: 18324274     EISSN: None     Source Type: Journal    
DOI: 10.1017/thg.2012.114     Document Type: Article

References (42)

1. Barker, D. J. (1990). The fetal and infant origins of adult disease. BMJ, 301, 1111.
2. Becker, A., Busjahn, A., Faulhaber, H. D., Bahring, S., Robertson, J., Schuster, H., & Luft, F. C. (1997). Twin zygosity. Automated determination with microsatellites. Journal of Reproductive Medicine, 42, 260-266.
3. Bibikova, M., Le, J., Barnes, B., Saedinia-Melnyk, S., Zhou, L., Shen, R., & Gunderson, K. L. (2009). Genome-wide methylation profiling using Infinium assay. Epigenomics, 1, 177-200.
4. Bird, A. (2007). Perceptions of epigenetics. Nature, 447, 396-398.
5. Carroll, S. G., Soothill, P. W., Abdel-Fattah, S. A., Porter, H., Montague, I., & Kyle, P. M. (2002). Prediction of chorionicity in twin pregnancies at 10-14 weeks of gestation. BJOG, 109, 182-186.
6. Cooney, C. A., Dave, A. A., & Wolff, G. L. (2002). Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring. The Journal of Nutrition, 132(8 Suppl), 2393S-2400S.
7. D'Alton, M. E., & Dudley, D. K. (1989). The ultrasonographic prediction of chorionicity in twin gestation. American Journal of Obstetrics and Gynecology, 160, 557-561.
8. Editorial. (2012). Clues from baby blood spots. Nature, 488, 560-561.
9. Fraga, M. F., Ballestar, E., Paz, M. F., Ropero, S., Setien, F., Ballestar, M. L., Esteller, M. (2005). Epigenetic differences arise during the lifetime of monozygotic twins. Proceedings of the National Academy of Sciences, 102, 10604-10609.
10. Gluckman, P. D., Hanson, M. A., & Beedle, A. S. (2007). Early life events and their consequences for later disease: A life history and evolutionary perspective. American Journal of Human Biology, 19, 1-19.
11. Gluckman, P. D., Hanson, M. A., Buklijas, T., Low, F. M., & Beedle, A. S. (2009). Epigenetic mechanisms that underpin metabolic and cardiovascular diseases. Nature Reviews. Endocrinology, 5, 401-408.
12. Gordon, L., Joo, J. H., Andronikos, R., Ollikainen, M., Wallace, E. M., Umstad, M. P., Craig, J. M. (2011). Expression discordance of monozygotic twins at birth: Effect of intrauterine environment and a possible mechanism for fetal programming. Epigenetics, 6, 579-592.
13. Gordon, L., Joo, J. E., Powell, J. E., Ollikainen, M., Novakovic, B., Li, X., Saffery, R. (2012).Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence. Genome Research, 22, 1395-1406.
14. Hack, K. E., Derks, J. B., Elias, S. G., Franx, A., Roos, E. J., Voerman, S. K., Visser, G. H. (2008). Increased perinatal mortality and morbidity in monochorionic versus dichorionic twin pregnancies: Clinical implications of a large Dutch cohort study. BJOG, 115, 58-67.
15. Hatkar, P.A., & Bhide, A.G. (1999). Perinatal outcome of twins in relation to chorionicity. Journal of PostgraduateMedicine, 45, 33-37.
16. Heijmans, B. T., Tobi, E. W., Stein, A. D., Putter, H., Blauw, G. J., Susser, E. S., .Lumey, L. H. (2008). Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proceedings of the National Academy of Sciences of the United States of America, 105, 17046-17049.
17. Holick, M. F. (2007). Vitamin D deficiency. New England Journal of Medicine, 357, 266-281.
18. IOM. (2011). Dietary Reference Intakes for Calcium and Vitamin D (No. 978-0-309-16394-1). Washington, DC: The National Academies.
19. Jackola, D. R. (2007). Random allergen-specific IgE expression in atopic families: Evidence for inherited 'stochastic bias' in adverse immune response development to non-infectious antigens. Molecular Immunology, 44, 2549-2557.
20. Jackola, D. R., Miller, M. B., Liebeler, C. L., & Blumenthal, M. N. (2007). Search for quantitative trait loci of atopy-associated immune responses using allergen-specific IgG1 as an 'endophenotype'. Human Immunology, 68, 839-843.
21. Jermendy, G., Horvath, T., Littvay, L., Steinbach, R., Jermendy, A. L., Tarnoki, A. D., Osztovits, J. (2011). Effect of genetic and environmental influences on cardiometabolic risk factors: A twin study. Cardiovascular Diabetology, 10, 96.
22. Jones, G., Prosser, D. E., & Kaufmann, M. (2012). 25- Hydroxyvitamin D-24-hydroxylase (CYP24A1): Its important role in the degradation of vitamin D. Archives of Biochemistry and Biophysics, 523, 9-18.
23. Leduc, L., Takser, L., & Rinfret, D. (2005). Persistance of adverse obstetric and neonatal outcomes in monochorionic twins after exclusion of disorders unique to monochorionic placentation. American Journal of Obstetrics and Gynecology, 193(5), 1670-1675.
24. Liebeler, C. L., Basu, S., & Jackola, D. R. (2007). Allergenspecific IgG1 provides parsimonious heritability estimates for atopy-associated immune responses to allergens. Human Immunology, 68, 113-121.
25. Liu, X., Zhang, S., Tsai, H. J., Hong, X., Wang, B., Fang, Y., Wang, X. (2009). Genetic and environmental contributions to allergen sensitization in a Chinese twin study. Clinical and Experimental Allergy, 39, 991-998.
26. Middelberg, R. P., Martin, N. G., & Whitfield, J. B. (2007). A longitudinal genetic study of plasma lipids in adolescent twins. Twin Research and Human Genetics, 10, 127-135.
27. Novakovic, B., Galati, J.C., Chen, A., Morley, R., Craig, J.M., & Saffery, R. (2012). Maternal vitamin D predominates over genetic factors in determining neonatal circulating vitamin D concentrations. American Journal of Clinical Nutrition, 96(1), 188-195.
28. Novakovic, B., Sibson, M., Ng, H. K., Manuelpillai, U., Rakyan, V., Down, T., Saffery, R. (2009). Placenta-specific methylation of the vitamin D 24-hydroxylase gene: Implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface. The Journal of Biological Chemistry, 284, 14838-14848.
29. Ollikainen, M., Smith, K. R., Joo, E. J., Ng, H. K., Andronikos, R., Novakovic, B., Craig, J. M. (2010).DNA methylation analysis ofmultiple tissues fromnewborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome. Human Molecular Genetics, 19, 4176-4188.
30. Osztovits, J., Horvath, T., Littvay, L., Steinbach, R., Jermendy, A., Tarnoki, A., Jermendy, G. (2011).Effects of genetic vs. environmental factors on cardiovascular autonomic function: A twin study. Diabetic Medicine, 28, 1241-1248.
31. Rajendram, R., Ferreira, J. C., Grafodatskaya, D., Choufani, S., Chiang, T., Pu, S., Weksberg, R. (2011). Assessment of methylation level prediction accuracy in methyl-DNA immunoprecipitation and sodium bisulfite based microarray platforms. Epigenetics, 6, 410-415.
32. Rao, A., Sairam, S., & Shehata, H. (2004). Obstetric complications of twinpregnancies. [Review]. Best practice&research. Clinical obstetrics & gynaecology, 18, 557-576.
33. Saffery, R., Morley, R., Carlin, J. B., Joo, J. H., Ollikainen, M., Novakovic, B., Craig, J. M. (2011). Cohort profile: The peri/post-natal epigenetic twins study. International Journal of Epidemiology, 41, 55-61.
34. Shin, J. S., Choi, M. Y., Longtine, M. S., & Nelson, D. M. (2010). Vitamin D effects on pregnancy and the placenta. Placenta, 31(12), 1027-1034.
35. Steegers-Theunissen, R. P., Obermann-Borst, S. A., Kremer, D., Lindemans, J., Siebel, C., Steegers, E. A., .Heijmans, B. T. (2009). Periconceptional maternal folic acid use of 400 microg per day is related to increased methylation of the IGF2 gene in the very young child. PLoS One, 4, e7845.
36. Struwe, E., Berzl, G., Schild, R., Blessing, H., Drexel, L., Hauck, B., Dotsch, J. (2010).Microarray analysis of placental tissue in intrauterine growth restriction. Clinical Endocrinology (Oxford), 72, 241-247.
37. Tobi, E. W., Lumey, L.H., Talens, R. P., Kremer, D., Putter, H., Stein, A. D., .Heijmans, B. T. (2009). DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific. Human Molecular Genetics, 18, 4046-4053.
38. Touvier, T., Conte-Auriol, F., Briand, O., Cudejko, C., Paumelle, R., Caron, S., Bailleu, B. (2009). LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice. The Journal of Clinical Investigation, 119, 3830-3838.
39. Umstad, M. P., Short, R. V., Wilson, M., & Craig, J. M. (2012). Chimaeric twins: why monochorionicity does not guarantee monozygosity. The Australian & New Zealand Journal of Obstetrics & Gynaecology, 52, 305-307.
40. Waddington, C. H. (1942). The epigenotype. Endeavour, 1, 18-20.
41. Weisenberger, D. J., Van Den Berg, D., Pan, F., Berman, B. P., & Laird, P. W. (2008). Comprehensive DNA Methylation Analysis on the Illumina R- Infinium R- Assay Platform.
42. Wong, N., Morley, R., Saffery, R., & Craig, J. (2008). Archived Guthrie blood spots as a novel source for quantitative DNA methylation analysis. BioTechniques, 45, 423-424, 426, 428 passim.