Moving forward with reactive oxygen species involvement in antimicrobial lethality

Journal of Antimicrobial Chemotherapy

Volumn 70, Issue 3, 2015, Pages 639-642

  Zhao, Xilin ^a,b,c   Hong, Yuzhi ^a   Drlica, Karl ^a,b  

^a PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^c XIAMEN UNIVERSITY   (China)

Author keywords

Antibiotics; Killing; Post damage cellular response; ROS

Indexed keywords

AMPICILLIN; BETA LACTAM ANTIBIOTIC; GENTAMICIN; KANAMYCIN; NORFLOXACIN; REACTIVE OXYGEN METABOLITE;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERICIDAL ACTIVITY; BACTERIOSTASIS; HYPOTHESIS; LETHALITY; NONHUMAN; STRESS; BACTERIUM; DRUG EFFECTS; MICROBIAL VIABILITY;

BACTERIA; MICROBIAL VIABILITY; REACTIVE OXYGEN SPECIES;

EID: 84928181275     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dku463     Document Type: Article

References (42)

1. Kohanski M, Dwyer D, Hayete B et al. A common mechanism of cellular death induced by bactericidal antibiotics. Cell 2007; 130: 797-810.
2. Arriaga-Alba M, Rivera-Sanchez R, Parra-Cervantes G et al. Antimutagenesis of b-carotene to mutations induced by quinolone on Salmonella typhimurium. Arch Med Res 2000; 31: 156-61.
3. Becerra M, Albesa I. Oxidative stress induced by ciprofloxacin in Staphylococcus aureus. Biochem Biophys Res Commun 2002; 297: 1003-7.
4. Albesa I, Becerra M, Battan P et al. Oxidative stress involved in the antibacterial action of different antibiotics. Biochem Biophys Res Commun 2004; 317: 605-9.
5. Wang X, Zhao X. Contribution of oxidative damage to antimicrobial lethality. Antimicrob Agents Chemother 2009; 53: 1395-402.
6. Kohanski M, Dwyer D, Wierzbowski J et al. Mistranslation of membrane proteins and two-component system activation trigger antibioticmediated cell death. Cell 2008; 135: 679-90.
7. Davies B, Kohanski M, Simmons L et al. Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli. Mol Cell 2009; 36: 845-60.
8. Dorsey-Oresto A, Lu T, Mosel M et al. YihE kinase is a novel regulator of programmed cell death in bacteria. Cell Rep 2013; 3: 528-37.
9. Gusarov I, Shatalin K, Starodubtseva M et al. Endogenous nitric oxide protects bacteria against a wide spectrum of antibiotics. Science 2009; 325: 1380-4.
10. Shatalin K, Shatalina E, Mironov A et al. H2S: a universal defense against antibiotics in bacteria. Science 2011; 334: 986-90.
11. Foti J, Devadoss B, Winkler J et al. Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics. Science 2012; 336: 315-9.
12. Kohanski M, Dwyer D, Collins J. How antibiotics kill bacteria: from targets to networks. Nat Rev Microbiol 2010; 8: 423-35.
13. Malik M, Hussain S, Drlica K. Effect of anaerobic growth on quinolone lethalitywith Escherichia coli. Antimicrob Agents Chemother 2007; 51: 28-34.
14. Wang X, Zhao X, Malik M et al. Contribution of reactive oxygen species to pathways of quinolone-mediated bacterial cell death. J Antimicrob Chemother 2010; 65: 520-4.
15. Keren I, Wu Y, Inocencio J et al. Killing by bactericidal antibiotics does not depend on reactive oxygen species. Science 2013; 339: 1213-6.
16. Liu Y, Imlay J. Cell death from antibiotics without the involvement of reactive oxygen species. Science 2013; 339: 1210-3.
17. Dwyer D, Belenky P, Yang J et al. Antibiotics induce redox-related physiological alterations as part of their lethality. Proc Natl Acad Sci USA 2014; 111: E2100-9.
18. Ezraty B, Vergnes A, Banzhaf M et al. Fe-S cluster biosynthesis controls uptake of aminoglycosides in a ROS-less death pathway. Science 2013; 340: 1583-7.
19. Mahoney TF, Silhavy TJ. The Cpx stress response confers resistance to some, but not all, bactericidal antibiotics. J Bacteriol 2013; 195: 1869-74.
20. Fang F. Antibiotic and ROS linkage questioned. Nat Biotech 2013; 31: 415-6.
21. Wright G, Hung D, Helmann J. How antibiotics kill bacteria: new models needed? Nat Med 2013; 19: 544-5.
22. Hadlington S. Battleground develops over antibiotic killing mechanism. ChemistryWorld, 8 March 2013.
23. Balaban N, Gerdes K, Lewis K et al. A problem of persistence: still more questions than answers? Nat Rev Microbiol 2013; 11: 587-91.
24. Kuhnert N. One size does not fit all--bacterial cell death by antibiotics cannot be explained by the action of reactive oxygen species. AngewChem Int Ed 2013; 52: 10946-8.
25. Dwyer DJ, Collins JJ, Walker GC. Unraveling the physiological complexities of antibiotic lethality. Annu Rev Pharmacol Toxicol 2015; 55: 9.1-9.20.
26. Zhao X, Drlica K. Reactive oxygen species and the bacterial response to lethal stress. Current Opin Microbiol 2014; 21: 1-6.
27. Marathe S, Kumar R, Ajitkumar P et al. Curcumin reduces the antimicrobial activity of ciprofloxacin against Salmonella typhimurium and Salmonella typhi. J Antimicrob Chemother 2013; 68: 139-52.
28. Lewis K. Persister cells. Annu Rev Microbiol 2010; 64: 357-72.
29. Gerdes K, Maisonneuve E. Bacterial persistence and toxin-antitoxin loci. Annu Rev Microbiol 2012; 66: 103-23.
30. Liu Y, Liu X, Qu Y et al. Inhibitors of reactive oxygen species accumulation delay and/or reduce the lethality of several antistaphylococcal agents. Antimicrob Agents Chemother 2012; 56: 6048-50.
31. Engelberg-Kulka H, Amitai S, Kolodkin-Gal I et al. Bacterial programmed cell death and multicellular behavior in bacteria. PLoS Genet 2006; 2: e135.
32. Gerdes K, Christensen SK, Lobner-Olesen A. Prokaryotic toxin-antitoxin stress response loci. Nat Rev Microbiol 2005; 3: 371-82.
33. Zhang Y, Zhang J, Hoeflich K et al. MazF cleaves cellular mRNAs specifically at ACA to block protein synthesis in Escherichia coli. Mol Cell 2003; 12:913-23.
34. Burger RM, Drlica K. Superoxide protects Escherichia coli from bleomycin mediated lethality. J Inorg Biochem 2009; 103: 1273-7.
35. Mosel M, Li L, Drlica K et al. Superoxide-mediated protection of Escherichia coli from antimicrobials. Antimicrob Agents Chemother 2013; 57: 5755-9.
36. Wu Y, Vulic M, Keren I et al. Role of oxidative stress in persister tolerance. Antimicrob Agents Chemother 2012; 56: 4922-6.
37. Farr SB, Natvig DO, Kogoma T. Toxicity and mutagenicity of plumbagin and the induction of a possible new DNA repair pathway in Escherichia coli. J Bacteriol 1985; 164: 1309-16.
38. Wu X, Wang X, Drlica K et al. A toxin-antitoxin module in Bacillus subtilis can both mitigate and amplify effects of lethal stress. PLoS One 2011; 6:e23909.
39. Dwyer D, Camacho D, Kohanski Met al. Antibiotic-induced bacterial cell death exhibits physiological and biochemical hallmarks of apoptosis. Mol Cell 2012; 46: 561-72.
40. Hoeijmakers JH. DNA damage, aging, and cancer. New Engl J Med 2009; 361: 1475-85.
41. Malik M, Zhao X, Drlica K. Lethal fragmentation of bacterial chromosomes mediated by DNA gyrase and quinolones. Mol Microbiol 2006; 61:810-25.
42. Chen CR, Malik M, Snyder M et al. DNA gyrase and topoisomerase IV on the bacterial chromosome: quinolone-induced DNA cleavage. J Mol Biol 1996; 258: 627-37.