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Volumn 42, Issue 5, 2015, Pages 520-529

Curcumin ameliorates asthmatic airway inflammation by activating nuclear factor-E2-related factor 2/haem oxygenase (HO)-1 signalling pathway

Author keywords

Asthma; Curcumin; Nrf2 HO 1 pathway; Pro inflammation cytokine; RAW264.7 cell; SiRNA

Indexed keywords

CURCUMIN; HEMATOXYLIN; HEME OXYGENASE 1; IMMUNOGLOBULIN E; INTERLEUKIN 1BETA; INTERLEUKIN 6; NUCLEAR FACTOR; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; LIPOPOLYSACCHARIDE; OVALBUMIN; TRANSCRIPTION FACTOR NRF2;

EID: 84928177241     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/1440-1681.12384     Document Type: Article
Times cited : (72)

References (52)
  • 1
    • 84896862630 scopus 로고    scopus 로고
    • FIZZ1 promotes airway remodeling through the PI3K/Akt signaling pathway in asthma
    • Wang J, Li F, Yang M et al. FIZZ1 promotes airway remodeling through the PI3K/Akt signaling pathway in asthma. Exp. Ther. Med. 2014; 7: 1265-70.
    • (2014) Exp. Ther. Med. , vol.7 , pp. 1265-1270
    • Wang, J.1    Li, F.2    Yang, M.3
  • 2
    • 79954583352 scopus 로고    scopus 로고
    • Pathogenesis of airway inflammation in bronchial asthma
    • Nakagome K, Nagata M. Pathogenesis of airway inflammation in bronchial asthma. Auris Nasus Larynx 2011; 38: 555-63.
    • (2011) Auris Nasus Larynx , vol.38 , pp. 555-563
    • Nakagome, K.1    Nagata, M.2
  • 3
    • 47949119866 scopus 로고    scopus 로고
    • Pathogenesis of asthma
    • Holgate ST. Pathogenesis of asthma. Clin. Exp. Allergy 2008; 38: 872-97.
    • (2008) Clin. Exp. Allergy , vol.38 , pp. 872-897
    • Holgate, S.T.1
  • 5
    • 84900819594 scopus 로고    scopus 로고
    • Asthma research in China: A five-year review
    • Chen ZH, Wang PL, Shen HH. Asthma research in China: A five-year review. Respirology 2013; 18 (Suppl 3): 10-19.
    • (2013) Respirology , vol.18 , pp. 10-19
    • Chen, Z.H.1    Wang, P.L.2    Shen, H.H.3
  • 7
    • 84903219887 scopus 로고    scopus 로고
    • Zn/Ga-DFO iron-chelating complex attenuates the inflammatory process in a mouse model of asthma
    • Bibi H, Vinokur V, Waisman D et al. Zn/Ga-DFO iron-chelating complex attenuates the inflammatory process in a mouse model of asthma. Redox. Biol. 2014; 2: 814-19.
    • (2014) Redox. Biol. , vol.2 , pp. 814-819
    • Bibi, H.1    Vinokur, V.2    Waisman, D.3
  • 8
    • 84870362982 scopus 로고    scopus 로고
    • Enhanced bioavailability and efficiency of curcumin for the treatment of asthma by its formulation in solid lipid nanoparticles
    • Wang W, Zhu R, Xie Q et al. Enhanced bioavailability and efficiency of curcumin for the treatment of asthma by its formulation in solid lipid nanoparticles. Int. J. Nanomed. 2012; 7: 3667-77.
    • (2012) Int. J. Nanomed. , vol.7 , pp. 3667-3677
    • Wang, W.1    Zhu, R.2    Xie, Q.3
  • 9
    • 55949084512 scopus 로고    scopus 로고
    • Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature
    • Anand P, Thomas SG, Kunnumakkara AB et al. Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature. Biochem. Pharmacol. 2008; 76: 1590-611.
    • (2008) Biochem. Pharmacol. , vol.76 , pp. 1590-1611
    • Anand, P.1    Thomas, S.G.2    Kunnumakkara, A.B.3
  • 10
    • 16844371915 scopus 로고    scopus 로고
    • Induction of apoptosis by curcumin and its implications for cancer therapy
    • Karunagaran D, Rashmi R, Kumar TR. Induction of apoptosis by curcumin and its implications for cancer therapy. Curr. Cancer Drug Targets 2005; 5: 117-29.
    • (2005) Curr. Cancer Drug Targets , vol.5 , pp. 117-129
    • Karunagaran, D.1    Rashmi, R.2    Kumar, T.R.3
  • 11
    • 84866163421 scopus 로고    scopus 로고
    • Curcumin induces Nrf2 nuclear translocation and prevents glomerular hypertension, hyperfiltration, oxidant stress, and the decrease in antioxidant enzymes in 5/6 nephrectomized rats
    • Tapia E, Soto V, Ortiz-Vega KM et al. Curcumin induces Nrf2 nuclear translocation and prevents glomerular hypertension, hyperfiltration, oxidant stress, and the decrease in antioxidant enzymes in 5/6 nephrectomized rats. Oxid. Med. Cell. Longev. 2012; 2012: 269039.
    • (2012) Oxid. Med. Cell. Longev. , vol.2012 , pp. 269039
    • Tapia, E.1    Soto, V.2    Ortiz-Vega, K.M.3
  • 12
    • 66049148225 scopus 로고    scopus 로고
    • Curcumin ameliorates renal failure in 5/6 nephrectomized rats: Role of inflammation
    • Ghosh SS, Massey HD, Krieg R et al. Curcumin ameliorates renal failure in 5/6 nephrectomized rats: Role of inflammation. Am. J. Physiol. Renal. Physiol. 2009; 296: F1146-57.
    • (2009) Am. J. Physiol. Renal. Physiol. , vol.296 , pp. F1146-F1157
    • Ghosh, S.S.1    Massey, H.D.2    Krieg, R.3
  • 13
    • 33846602797 scopus 로고    scopus 로고
    • Curcumin, a Curcuma longa constituent, acts on MAPK p38 pathway modulating COX-2 and iNOS expression in chronic experimental colitis
    • Camacho-Barquero L, Villegas I, Sanchez-Calvo JM et al. Curcumin, a Curcuma longa constituent, acts on MAPK p38 pathway modulating COX-2 and iNOS expression in chronic experimental colitis. Int. Immunopharmacol. 2007; 7: 333-42.
    • (2007) Int. Immunopharmacol. , vol.7 , pp. 333-342
    • Camacho-Barquero, L.1    Villegas, I.2    Sanchez-Calvo, J.M.3
  • 14
    • 0036892994 scopus 로고    scopus 로고
    • Curcumin prevents and ameliorates trinitrobenzene sulfonic acid-induced colitis in mice
    • Sugimoto K, Hanai H, Tozawa K et al. Curcumin prevents and ameliorates trinitrobenzene sulfonic acid-induced colitis in mice. Gastroenterology 2002; 123: 1912-22.
    • (2002) Gastroenterology , vol.123 , pp. 1912-1922
    • Sugimoto, K.1    Hanai, H.2    Tozawa, K.3
  • 15
    • 84896779620 scopus 로고    scopus 로고
    • Curcumin attenuates inflammatory responses by suppressing TLR4-mediated NF-kappaB signaling pathway in lipopolysaccharide-induced mastitis in mice
    • Fu Y, Gao R, Cao Y et al. Curcumin attenuates inflammatory responses by suppressing TLR4-mediated NF-kappaB signaling pathway in lipopolysaccharide-induced mastitis in mice. Int. Immunopharmacol. 2014; 20: 54-8.
    • (2014) Int. Immunopharmacol. , vol.20 , pp. 54-58
    • Fu, Y.1    Gao, R.2    Cao, Y.3
  • 16
    • 84897574713 scopus 로고    scopus 로고
    • Curcumin ameliorates rat experimental autoimmune neuritis
    • Han F, Luo B, Shi R et al. Curcumin ameliorates rat experimental autoimmune neuritis. J. Neurosci. Res. 2014; 92: 743-50.
    • (2014) J. Neurosci. Res. , vol.92 , pp. 743-750
    • Han, F.1    Luo, B.2    Shi, R.3
  • 17
    • 84863728682 scopus 로고    scopus 로고
    • Curcumin attenuates TNF-alpha-induced expression of intercellular adhesion molecule-1, vascular cell adhesion molecule-1 and proinflammatory cytokines in human endometriotic stromal cells
    • Kim KH, Lee EN, Park JK et al. Curcumin attenuates TNF-alpha-induced expression of intercellular adhesion molecule-1, vascular cell adhesion molecule-1 and proinflammatory cytokines in human endometriotic stromal cells. Phytother. Res. 2012; 26: 1037-47.
    • (2012) Phytother. Res. , vol.26 , pp. 1037-1047
    • Kim, K.H.1    Lee, E.N.2    Park, J.K.3
  • 18
    • 84878089733 scopus 로고    scopus 로고
    • regs)/Th17 balance in ovalbumin-sensitized mice
    • regs)/Th17 balance in ovalbumin-sensitized mice. Fitoterapia 2013; 87: 57-64.
    • (2013) Fitoterapia , vol.87 , pp. 57-64
    • Ma, C.1    Ma, Z.2    Fu, Q.3    Ma, S.4
  • 19
    • 79960330994 scopus 로고    scopus 로고
    • Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF-kappaB inhibition
    • Oh SW, Cha JY, Jung JE et al. Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF-kappaB inhibition. J. Ethnopharmacol. 2011; 136: 414-21.
    • (2011) J. Ethnopharmacol. , vol.136 , pp. 414-421
    • Oh, S.W.1    Cha, J.Y.2    Jung, J.E.3
  • 20
    • 0034655773 scopus 로고    scopus 로고
    • Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress
    • Motterlini R, Foresti R, Bassi R, Green CJ. Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress. Free Rad. Biol. Med. 2000; 28: 1303-12.
    • (2000) Free Rad. Biol. Med. , vol.28 , pp. 1303-1312
    • Motterlini, R.1    Foresti, R.2    Bassi, R.3    Green, C.J.4
  • 21
    • 77954142468 scopus 로고    scopus 로고
    • Up-regulation of heme oxygenase-1 expression through CaMKII-ERK1/2-Nrf2 signaling mediates the anti-inflammatory effect of bisdemethoxycurcumin in LPS-stimulated macrophages
    • Kim AN, Jeon WK, Lee JJ, Kim BC. Up-regulation of heme oxygenase-1 expression through CaMKII-ERK1/2-Nrf2 signaling mediates the anti-inflammatory effect of bisdemethoxycurcumin in LPS-stimulated macrophages. Free Rad. Biol. Med. 2010; 49: 323-31.
    • (2010) Free Rad. Biol. Med. , vol.49 , pp. 323-331
    • Kim, A.N.1    Jeon, W.K.2    Lee, J.J.3    Kim, B.C.4
  • 22
    • 42949162968 scopus 로고    scopus 로고
    • Heme oxygenase-1 mediates the anti-inflammatory effect of Curcumin within LPS-stimulated human monocytes
    • Hsu HY, Chu LC, Hua KF, Chao LK. Heme oxygenase-1 mediates the anti-inflammatory effect of Curcumin within LPS-stimulated human monocytes. J. Cell. Physiol. 2008; 215: 603-12.
    • (2008) J. Cell. Physiol. , vol.215 , pp. 603-612
    • Hsu, H.Y.1    Chu, L.C.2    Hua, K.F.3    Chao, L.K.4
  • 23
    • 33645945014 scopus 로고    scopus 로고
    • Heme oxygenase-1/carbon monoxide: From basic science to therapeutic applications
    • Ryter SW, Alam J, Choi AM. Heme oxygenase-1/carbon monoxide: From basic science to therapeutic applications. Physiol. Rev. 2006; 86: 583-650.
    • (2006) Physiol. Rev. , vol.86 , pp. 583-650
    • Ryter, S.W.1    Alam, J.2    Choi, A.M.3
  • 24
    • 84928192507 scopus 로고    scopus 로고
    • Comparison of effectiveness of curcumin with triamcinolone acetonide in the gel form in treatment of minor recurrent aphthous stomatitis: A randomized clinical trial
    • Deshmukh RA, Bagewadi AS. Comparison of effectiveness of curcumin with triamcinolone acetonide in the gel form in treatment of minor recurrent aphthous stomatitis: A randomized clinical trial. Int. J. Pharm Investig. 2014; 4: 138-41.
    • (2014) Int. J. Pharm Investig. , vol.4 , pp. 138-141
    • Deshmukh, R.A.1    Bagewadi, A.S.2
  • 25
    • 84905083796 scopus 로고    scopus 로고
    • Curcumin induces human SKOV3 cell apoptosis via the activation of Rho-kinase
    • Yin Z, Sun J. Curcumin induces human SKOV3 cell apoptosis via the activation of Rho-kinase. Eur. J. Gynaecol. Oncol. 2014; 35: 433-7.
    • (2014) Eur. J. Gynaecol. Oncol. , vol.35 , pp. 433-437
    • Yin, Z.1    Sun, J.2
  • 26
    • 85013345348 scopus 로고    scopus 로고
    • Preparation and characterization of bionanoemulsions for improving and modulating the antioxidant efficacy of natural phenolic antioxidant curcumin
    • Malik P, Ameta RK, Singh M. Preparation and characterization of bionanoemulsions for improving and modulating the antioxidant efficacy of natural phenolic antioxidant curcumin. Chem. Biol. Interact. 2014; 222C: 77-86.
    • (2014) Chem. Biol. Interact. , vol.222C , pp. 77-86
    • Malik, P.1    Ameta, R.K.2    Singh, M.3
  • 27
    • 84899887529 scopus 로고    scopus 로고
    • Intranasal curcumin attenuates airway remodeling in murine model of chronic asthma
    • Chauhan PS, Sini S, Dash D, Singh R. Intranasal curcumin attenuates airway remodeling in murine model of chronic asthma. Int. Immunopharmacol. 2014; 21: 63-75.
    • (2014) Int. Immunopharmacol. , vol.21 , pp. 63-75
    • Chauhan, P.S.1    Sini, S.2    Dash, D.3    Singh, R.4
  • 28
    • 84927173556 scopus 로고    scopus 로고
    • The effect of serine protease inhibitors on airway inflammation in a chronic allergen-induced asthma mouse model
    • 8 79 326
    • Lin CC, Lin LJ, Wang SD et al. The effect of serine protease inhibitors on airway inflammation in a chronic allergen-induced asthma mouse model. Mediators Inflamm. 2014; 2014: 8 79 326.
    • (2014) Mediators Inflamm. , vol.2014
    • Lin, C.C.1    Lin, L.J.2    Wang, S.D.3
  • 29
    • 84918806590 scopus 로고    scopus 로고
    • Protective effect of curcumin on acute airway inflammation of allergic asthma in mice through Notch1-GATA3 signaling pathway
    • Chong L, Zhang W, Nie Y et al. Protective effect of curcumin on acute airway inflammation of allergic asthma in mice through Notch1-GATA3 signaling pathway. Inflammation 2014; 37: 1476-85.
    • (2014) Inflammation , vol.37 , pp. 1476-1485
    • Chong, L.1    Zhang, W.2    Nie, Y.3
  • 30
    • 84862798490 scopus 로고    scopus 로고
    • 4-Ketopinoresinol, a novel naturally occurring ARE activator, induces the Nrf2/HO-1 axis and protects against oxidative stress-induced cell injury via activation of PI3K/AKT signaling
    • Chen HH, Chen YT, Huang YW, Tsai HJ, Kuo CC. 4-Ketopinoresinol, a novel naturally occurring ARE activator, induces the Nrf2/HO-1 axis and protects against oxidative stress-induced cell injury via activation of PI3K/AKT signaling. Free Rad. Biol. Med. 2012; 52: 1054-66.
    • (2012) Free Rad. Biol. Med. , vol.52 , pp. 1054-1066
    • Chen, H.H.1    Chen, Y.T.2    Huang, Y.W.3    Tsai, H.J.4    Kuo, C.C.5
  • 31
    • 84873469216 scopus 로고    scopus 로고
    • The transcription factor NF-E2-related factor 2 (Nrf2): A protooncogene?
    • Shelton P, Jaiswal AK. The transcription factor NF-E2-related factor 2 (Nrf2): A protooncogene? FASEB J. 2013; 27: 414-23.
    • (2013) FASEB J. , vol.27 , pp. 414-423
    • Shelton, P.1    Jaiswal, A.K.2
  • 32
    • 84885944468 scopus 로고    scopus 로고
    • The emerging role of the Nrf2-Keap1 signaling pathway in cancer
    • Jaramillo MC, Zhang DD. The emerging role of the Nrf2-Keap1 signaling pathway in cancer. Genes Dev. 2013; 27: 2179-91.
    • (2013) Genes Dev. , vol.27 , pp. 2179-2191
    • Jaramillo, M.C.1    Zhang, D.D.2
  • 33
    • 84864348569 scopus 로고    scopus 로고
    • NRF2 and cancer: The good, the bad and the importance of context
    • Sporn MB, Liby KT. NRF2 and cancer: The good, the bad and the importance of context. Nat. Rev. Cancer 2012; 12: 564-71.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 564-571
    • Sporn, M.B.1    Liby, K.T.2
  • 34
    • 39149106003 scopus 로고    scopus 로고
    • Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1
    • Farombi EO, Shrotriya S, Na HK, Kim SH, Surh YJ. Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1. Food Chem. Toxicol. 2008; 46: 1279-87.
    • (2008) Food Chem. Toxicol. , vol.46 , pp. 1279-1287
    • Farombi, E.O.1    Shrotriya, S.2    Na, H.K.3    Kim, S.H.4    Surh, Y.J.5
  • 35
    • 33344469643 scopus 로고    scopus 로고
    • Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1
    • Kobayashi A, Kang MI, Watai Y et al. Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1. Mol. Cell. Biol. 2006; 26: 221-9.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 221-229
    • Kobayashi, A.1    Kang, M.I.2    Watai, Y.3
  • 36
    • 84881071384 scopus 로고    scopus 로고
    • Role of AMP-activated protein kinase in ferritin H gene expression by resveratrol in human T cells
    • Iwasaki K, Ray PD, Huang BW, Sakamoto K, Kobayashi T, Tsuji Y. Role of AMP-activated protein kinase in ferritin H gene expression by resveratrol in human T cells. Biochemistry 2013; 52: 5075-83.
    • (2013) Biochemistry , vol.52 , pp. 5075-5083
    • Iwasaki, K.1    Ray, P.D.2    Huang, B.W.3    Sakamoto, K.4    Kobayashi, T.5    Tsuji, Y.6
  • 37
    • 84884884530 scopus 로고    scopus 로고
    • Therapeutic roles of heme oxygenase-1 in metabolic diseases: curcumin and resveratrol analogues as possible inducers of heme oxygenase-1
    • Son Y, Lee JH, Chung HT, Pae HO. Therapeutic roles of heme oxygenase-1 in metabolic diseases: curcumin and resveratrol analogues as possible inducers of heme oxygenase-1. Oxid. Med. Cell. Longev. 2013; 2013: 6 39 541.
    • (2013) Oxid. Med. Cell. Longev. , vol.2013 , pp. 6 39 541
    • Son, Y.1    Lee, J.H.2    Chung, H.T.3    Pae, H.O.4
  • 38
    • 84906928528 scopus 로고    scopus 로고
    • Nrf2 null enhances UVB-induced skin inflammation and extracellular matrix damages
    • Saw CL, Yang AY, Huang MT et al. Nrf2 null enhances UVB-induced skin inflammation and extracellular matrix damages. Cell Biosci. 2014; 4: 39.
    • (2014) Cell Biosci. , vol.4 , pp. 39
    • Saw, C.L.1    Yang, A.Y.2    Huang, M.T.3
  • 39
    • 40849100144 scopus 로고    scopus 로고
    • Pharmacological preconditioning with simvastatin protects liver from ischemia-reperfusion injury by heme oxygenase-1 induction
    • Lai IR, Chang KJ, Tsai HW, Chen CF. Pharmacological preconditioning with simvastatin protects liver from ischemia-reperfusion injury by heme oxygenase-1 induction. Transplantation 2008; 85: 732-8.
    • (2008) Transplantation , vol.85 , pp. 732-738
    • Lai, I.R.1    Chang, K.J.2    Tsai, H.W.3    Chen, C.F.4
  • 40
    • 79952120959 scopus 로고    scopus 로고
    • Curcumin induces heme oxygenase-1 in normal human skin fibroblasts through redox signaling: Relevance for anti-aging intervention
    • Lima CF, Pereira-Wilson C, Rattan SI. Curcumin induces heme oxygenase-1 in normal human skin fibroblasts through redox signaling: Relevance for anti-aging intervention. Mol. Nutr. Food Res. 2011; 55: 430-42.
    • (2011) Mol. Nutr. Food Res. , vol.55 , pp. 430-442
    • Lima, C.F.1    Pereira-Wilson, C.2    Rattan, S.I.3
  • 41
    • 84884579529 scopus 로고    scopus 로고
    • Curcumin ameliorates TNF-alpha-induced ICAM-1 expression and subsequent THP-1 adhesiveness via the induction of heme oxygenase-1 in the HaCaT cells
    • Youn GS, Kwon DJ, Ju SM, Choi SY, Park J. Curcumin ameliorates TNF-alpha-induced ICAM-1 expression and subsequent THP-1 adhesiveness via the induction of heme oxygenase-1 in the HaCaT cells. BMB Rep. 2013; 46: 410-15.
    • (2013) BMB Rep. , vol.46 , pp. 410-415
    • Youn, G.S.1    Kwon, D.J.2    Ju, S.M.3    Choi, S.Y.4    Park, J.5
  • 42
    • 84872589717 scopus 로고    scopus 로고
    • Beyond NF-kappaB activation: Nuclear functions of IkappaB kinase alpha
    • Huang WC, Hung MC. Beyond NF-kappaB activation: Nuclear functions of IkappaB kinase alpha. J. Biomed. Sci. 2013; 20: 3.
    • (2013) J. Biomed. Sci. , vol.20 , pp. 3
    • Huang, W.C.1    Hung, M.C.2
  • 44
    • 84912083860 scopus 로고    scopus 로고
    • Long-term effect of curcumin down-regulates expression of tumor necrosis factor-alpha and interleukin-6 via modulation of E26 transformation-specific protein and nuclear factor-kappaB transcription factors in livers of lymphoma bearing mice
    • Das L, Vinayak M. Long-term effect of curcumin down-regulates expression of tumor necrosis factor-alpha and interleukin-6 via modulation of E26 transformation-specific protein and nuclear factor-kappaB transcription factors in livers of lymphoma bearing mice. Leuk. Lymphoma 2014; 55: 2627-36.
    • (2014) Leuk. Lymphoma , vol.55 , pp. 2627-2636
    • Das, L.1    Vinayak, M.2
  • 45
    • 84897945579 scopus 로고    scopus 로고
    • The role IL-1 in tumor-mediated angiogenesis
    • Voronov E, Carmi Y, Apte RN. The role IL-1 in tumor-mediated angiogenesis. Front. Physiol. 2014; 5: 114.
    • (2014) Front. Physiol. , vol.5 , pp. 114
    • Voronov, E.1    Carmi, Y.2    Apte, R.N.3
  • 46
    • 84907813715 scopus 로고    scopus 로고
    • Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: The prevention of curcumin
    • Xu D, Hu L, Su C et al. Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: The prevention of curcumin. Toxicol. Appl. Pharmacol. 2014; 280: 305-13.
    • (2014) Toxicol. Appl. Pharmacol. , vol.280 , pp. 305-313
    • Xu, D.1    Hu, L.2    Su, C.3
  • 47
    • 84924104447 scopus 로고    scopus 로고
    • Curcumin improves hypoxia induced dysfunctions in 3T3-L1 adipocytes by protecting mitochondria and down regulating inflammation
    • Priyanka A, Anusree SS, Nisha VM, Raghu KG. Curcumin improves hypoxia induced dysfunctions in 3T3-L1 adipocytes by protecting mitochondria and down regulating inflammation. BioFactors 2014; 40: 513-23.
    • (2014) BioFactors , vol.40 , pp. 513-523
    • Priyanka, A.1    Anusree, S.S.2    Nisha, V.M.3    Raghu, K.G.4
  • 48
    • 84904578762 scopus 로고    scopus 로고
    • pH-sensitive nanoparticles for colonic delivery of curcumin in inflammatory bowel disease
    • Beloqui A, Coco R, Memvanga PB, Ucakar B, des Rieux A, Preat V. pH-sensitive nanoparticles for colonic delivery of curcumin in inflammatory bowel disease. Int. J. Pharm. 2014; 473: 203-12.
    • (2014) Int. J. Pharm. , vol.473 , pp. 203-212
    • Beloqui, A.1    Coco, R.2    Memvanga, P.B.3    Ucakar, B.4    des Rieux, A.5    Preat, V.6
  • 49
    • 84897115945 scopus 로고    scopus 로고
    • Baicalein, an active component of Scutellaria baicalensis, protects against lipopolysaccharide-induced acute lung injury in rats
    • Tsai CL, Lin YC, Wang HM, Chou TC. Baicalein, an active component of Scutellaria baicalensis, protects against lipopolysaccharide-induced acute lung injury in rats. J. Ethnopharmacol. 2014; 153: 197-206.
    • (2014) J. Ethnopharmacol. , vol.153 , pp. 197-206
    • Tsai, C.L.1    Lin, Y.C.2    Wang, H.M.3    Chou, T.C.4
  • 50
    • 84899688915 scopus 로고    scopus 로고
    • Protective effects of the polyphenol sesamin on allergen-induced T(H)2 responses and airway inflammation in mice
    • Lin CH, Shen ML, Zhou N, Lee CC, Kao ST, Wu DC. Protective effects of the polyphenol sesamin on allergen-induced T(H)2 responses and airway inflammation in mice. PLoS ONE 2014; 9: e96091.
    • (2014) PLoS ONE , vol.9 , pp. e96091
    • Lin, C.H.1    Shen, M.L.2    Zhou, N.3    Lee, C.C.4    Kao, S.T.5    Wu, D.C.6
  • 51
    • 84965189319 scopus 로고    scopus 로고
    • Echinococcus granulosus infection reduces airway inflammation of mice likely through enhancing IL-10 and down-regulation of IL-5 and IL-17A
    • Wang H, Li J, Pu H et al. Echinococcus granulosus infection reduces airway inflammation of mice likely through enhancing IL-10 and down-regulation of IL-5 and IL-17A. Parasit. Vectors 2014; 7: 522.
    • (2014) Parasit. Vectors , vol.7 , pp. 522
    • Wang, H.1    Li, J.2    Pu, H.3
  • 52
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001; 25: 402-8.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.