Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: The prevention of curcumin

Toxicology and Applied Pharmacology

Volumn 280, Issue 2, 2014, Pages 305-313

  Xu, Demei ^a   Hu, Lihua ^a   Su, Chuanyang ^a   Xia, Xiaomin ^a   Zhang, Pu ^a   Fu, Juanli ^a   Wang, Wenchao ^a   Xu, Duo ^a   Du, Hong ^a   Hu, Qiuling ^a   Song, Erqun ^a   Song, Yang ^a  

^a SOUTHWEST UNIVERSITY   (China)

Author keywords

Antioxidant; Hepatoprotection; Inflammation; NF B; TCBQ; TNF

Indexed keywords

1,4 BENZOQUINONE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CASPASE 3; CASPASE 8; CASPASE 9; CATALASE; CURCUMIN; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; PROTEIN BAX; PROTEIN BCL 2; SUPEROXIDE DISMUTASE; TETRACHLORO P BENZOQUINONE; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; BENZOQUINONE DERIVATIVE; CASPASE; CHLORINATED HYDROCARBON; NFE2L2 PROTEIN, MOUSE; NOS2 PROTEIN, MOUSE; TETRACHLOROBENZOQUINONE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; HEPATITIS; HISTOPATHOLOGY; LIPID PEROXIDATION; LIVER HOMOGENATE; LIVER INJURY; LIVER PROTECTION; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; BLOOD; CHEMICALLY INDUCED; DRUG EFFECTS; INFLAMMATION; LIVER; METABOLISM; PATHOLOGY; PHYSIOLOGY; TOXICITY;

ALANINE TRANSAMINASE; ANIMALS; APOPTOSIS; ASPARTATE AMINOTRANSFERASES; BENZOQUINONES; CASPASES; CURCUMIN; HYDROCARBONS, CHLORINATED; INFLAMMATION; INTERLEUKIN-6; LIVER; MALE; MICE; NF-E2-RELATED FACTOR 2; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 84907813715     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2014.08.003     Document Type: Article

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