-
1
-
-
68049105101
-
Rab GTPases as coordinators of vesicle traffic
-
Stenmark, H. Rab GTPases as coordinators of vesicle traffic. Nat Rev Mol Cell Biol 10, 513-525, doi:10.1038/nrm2728 (2009).
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 513-525
-
-
Stenmark, H.1
-
2
-
-
52549126992
-
Regulation of secretory vesicle traffic by Rab small GTPases
-
Fukuda, M. Regulation of secretory vesicle traffic by Rab small GTPases. Cell Mol Life Sci 65, 2801-2813, doi:10.1007/s00018-008-8351-4 (2008).
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 2801-2813
-
-
Fukuda, M.1
-
3
-
-
3442877345
-
Griscelli syndrome: Characterization of a new mutation and rescue of T-cytotoxic activity by retroviral transfer of RAB27A gene
-
Bizario, J. C. et al. Griscelli syndrome: characterization of a new mutation and rescue of T-cytotoxic activity by retroviral transfer of RAB27A gene. J Clin Immunol 24, 397-410, doi:10.1023/B:JOCI.0000029119 (2004).
-
(2004)
J Clin Immunol
, vol.24
, pp. 397-410
-
-
Bizario, J.C.1
-
4
-
-
0344002689
-
Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome
-
Menasche, G. et al. Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome. Nat Genet 25, 173-176, doi:10.1038/76024 (2000).
-
(2000)
Nat Genet
, vol.25
, pp. 173-176
-
-
Menasche, G.1
-
5
-
-
84861164214
-
Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activating protein Geminteracting protein
-
Johnson, J. L., Monfregola, J., Napolitano, G., Kiosses, W. B. & Catz, S. D. Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activating protein Geminteracting protein. Mol Biol Cell 23, 1902-1916, doi:10.1091/mbc.E11-12-1001 (2012).
-
(2012)
Mol Biol Cell
, vol.23
, pp. 1902-1916
-
-
Johnson, J.L.1
Monfregola, J.2
Napolitano, G.3
Kiosses, W.B.4
Catz, S.D.5
-
6
-
-
0033923370
-
Lysosome-related organelles
-
Dell'Angelica, E. C., Mullins, C., Caplan, S. & Bonifacino, J. S. Lysosome-related organelles. FASEB J 14, 1265-1278 (2000).
-
(2000)
FASEB J
, vol.14
, pp. 1265-1278
-
-
Dell'Angelica, E.C.1
Mullins, C.2
Caplan, S.3
Bonifacino, J.S.4
-
7
-
-
84883450687
-
Lysosome-related organelles: Unusual compartments become mainstream
-
Marks, M. S., Heijnen, H. F. & Raposo, G. Lysosome-related organelles: unusual compartments become mainstream. Curr Opin Cell Biol 25, 495-505, doi:10.1016/j.ceb.2013.04.008 (2013).
-
(2013)
Curr Opin Cell Biol
, vol.25
, pp. 495-505
-
-
Marks, M.S.1
Heijnen, H.F.2
Raposo, G.3
-
8
-
-
0036219181
-
The dark side of lysosome-related organelles: Specialization of the endocytic pathway for melanosome biogenesis
-
Raposo, G. & Marks, M. S. The dark side of lysosome-related organelles: specialization of the endocytic pathway for melanosome biogenesis. Traffic 3, 237-248 (2002).
-
(2002)
Traffic
, vol.3
, pp. 237-248
-
-
Raposo, G.1
Marks, M.S.2
-
9
-
-
84870178750
-
Rab27a and melanosomes: A model to investigate the membrane targeting of Rabs
-
Booth, A. E., Seabra, M. C. & Hume, A. N. Rab27a and melanosomes: a model to investigate the membrane targeting of Rabs. Biochem Soc Trans 40, 1383-1388, doi:10.1042/BST20120200 (2012).
-
(2012)
Biochem Soc Trans
, vol.40
, pp. 1383-1388
-
-
Booth, A.E.1
Seabra, M.C.2
Hume, A.N.3
-
10
-
-
0035911150
-
Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen mice
-
Haddad, E. K., Wu, X., Hammer, J. A. 3rd. & Henkart, P. A. Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen mice. J Cell Biol 152, 835-842 (2001).
-
(2001)
J Cell Biol
, vol.152
, pp. 835-842
-
-
Haddad, E.K.1
Wu, X.2
Hammer, J.A.3
Henkart, P.A.4
-
11
-
-
0036660163
-
The regulation of platelet-dense granules by Rab27a in the ashen mouse, a model of Hermansky-Pudlak and Griscelli syndromes, is granulespecific and dependent on genetic background
-
Novak, E. K. et al. The regulation of platelet-dense granules by Rab27a in the ashen mouse, a model of Hermansky-Pudlak and Griscelli syndromes, is granulespecific and dependent on genetic background. Blood 100, 128-135 (2002).
-
(2002)
Blood
, vol.100
, pp. 128-135
-
-
Novak, E.K.1
-
12
-
-
0022348139
-
Cell-mediated extracellular acidification and bone resorption: Evidence for a low pH in resorbing lacunae and localization of a 100-kD lysosomal membrane protein at the osteoclast ruffled border
-
Baron, R., Neff, L., Louvard, D. & Courtoy, P. J. Cell-mediated extracellular acidification and bone resorption: evidence for a low pH in resorbing lacunae and localization of a 100-kD lysosomal membrane protein at the osteoclast ruffled border. J Cell Biol 101, 2210-2222 (1985).
-
(1985)
J Cell Biol
, vol.101
, pp. 2210-2222
-
-
Baron, R.1
Neff, L.2
Louvard, D.3
Courtoy, P.J.4
-
13
-
-
0033304730
-
Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families
-
Suda, T. et al. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr Rev 20, 345-357 (1999).
-
(1999)
Endocr Rev
, vol.20
, pp. 345-357
-
-
Suda, T.1
-
14
-
-
0043267732
-
Genetic regulation of osteoclast development and function
-
Teitelbaum, S. L. & Ross, F. P. Genetic regulation of osteoclast development and function. Nat Rev Genet 4, 638-649, doi:10.1038/nrg1122 (2003).
-
(2003)
Nat Rev Genet
, vol.4
, pp. 638-649
-
-
Teitelbaum, S.L.1
Ross, F.P.2
-
15
-
-
85003152202
-
Modulation of osteoclast differentiation
-
Suda, T., Takahashi, N. & Martin, T. J. Modulation of osteoclast differentiation. Endocr Rev 13, 66-80 (1992).
-
(1992)
Endocr Rev
, vol.13
, pp. 66-80
-
-
Suda, T.1
Takahashi, N.2
Martin, T.J.3
-
16
-
-
0029127505
-
The osteoclast clear zone is a specialized cellextracellular matrix adhesion structure
-
Vaananen, H. K. & Horton, M. The osteoclast clear zone is a specialized cellextracellular matrix adhesion structure. J Cell Sci 108 (Pt 8), 2729-2732 (1995).
-
(1995)
J Cell Sci
, vol.108
, Issue.8
, pp. 2729-2732
-
-
Vaananen, H.K.1
Horton, M.2
-
17
-
-
0033994430
-
The cell biology of osteoclast function
-
Vaananen, H. K., Zhao, H., Mulari, M. & Halleen, J. M. The cell biology of osteoclast function. J Cell Sci 113 (Pt 3), 377-381 (2000).
-
(2000)
J Cell Sci
, vol.113
, Issue.3
, pp. 377-381
-
-
Vaananen, H.K.1
Zhao, H.2
Mulari, M.3
Halleen, J.M.4
-
18
-
-
84882567717
-
Osteopetrosis: Genetics, treatment and new insights into osteoclast function
-
Sobacchi, C., Schulz, A., Coxon, F. P., Villa, A. & Helfrich, M. H. Osteopetrosis: genetics, treatment and new insights into osteoclast function. Nat Rev Endocrinol 9, 522-536, doi:10.1038/nrendo.2013.137 (2013).
-
(2013)
Nat Rev Endocrinol
, vol.9
, pp. 522-536
-
-
Sobacchi, C.1
Schulz, A.2
Coxon, F.P.3
Villa, A.4
Helfrich, M.H.5
-
19
-
-
84883562970
-
Regulation of lysosome biogenesis and functions in osteoclasts
-
Lacombe, J., Karsenty, G. & Ferron, M. Regulation of lysosome biogenesis and functions in osteoclasts. Cell Cycle 12, 2744-2752, doi:10.4161/cc.25825 (2013).
-
(2013)
Cell Cycle
, vol.12
, pp. 2744-2752
-
-
Lacombe, J.1
Karsenty, G.2
Ferron, M.3
-
20
-
-
0032506007
-
Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice
-
Saftig, P. et al. Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice. Proc Natl Acad Sci U S A 95, 13453-13458 (1998).
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 13453-13458
-
-
Saftig, P.1
-
21
-
-
0034473275
-
Functions of cathepsin K in bone resorption. Lessons from cathepsin K deficient mice
-
Saftig, P. et al. Functions of cathepsin K in bone resorption. Lessons from cathepsin K deficient mice. Adv Exp Med Biol 477, 293-303, doi:10.1007/0-306-46826-3-32 (2000).
-
(2000)
Adv Exp Med Biol
, vol.477
, pp. 293-303
-
-
Saftig, P.1
-
22
-
-
84873401233
-
Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation
-
Lotinun, S. et al. Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation. J Clin Invest 123, 666-681, doi:10.1172/jci64840 (2013).
-
(2013)
J Clin Invest
, vol.123
, pp. 666-681
-
-
Lotinun, S.1
-
23
-
-
34250781583
-
Altered collagen in tartrate-resistant acid phosphatase (TRAP)-deficient mice: A role for TRAP in bone collagen metabolism
-
Roberts, H. C. et al. Altered collagen in tartrate-resistant acid phosphatase (TRAP)-deficient mice: a role for TRAP in bone collagen metabolism. Calcif Tissue Int 80, 400-410, doi:10.1007/s00223-007-9032-2 (2007).
-
(2007)
Calcif Tissue Int
, vol.80
, pp. 400-410
-
-
Roberts, H.C.1
-
24
-
-
0039778099
-
Intracellular fragmentation of bone resorption products by reactive oxygen species generated by osteoclastic tartrate-resistant acid phosphatase
-
Halleen, J. M. et al. Intracellular fragmentation of bone resorption products by reactive oxygen species generated by osteoclastic tartrate-resistant acid phosphatase. J Biol Chem 274, 22907-22910 (1999).
-
(1999)
J Biol Chem
, vol.274
, pp. 22907-22910
-
-
Halleen, J.M.1
-
25
-
-
0842325055
-
Direct stimulation of osteoclastogenesis by MIP-1alpha: Evidence obtained from studies using RAW264 cell clone highly responsive to RANKL
-
Watanabe, T. et al. Direct stimulation of osteoclastogenesis by MIP-1alpha: evidence obtained from studies using RAW264 cell clone highly responsive to RANKL. J Endocrinol 180, 193-201 (2004).
-
(2004)
J Endocrinol
, vol.180
, pp. 193-201
-
-
Watanabe, T.1
-
26
-
-
12944255844
-
A mutation in Rab27a causes the vesicle transport defects observed in ashen mice
-
Wilson, S. M. et al. A mutation in Rab27a causes the vesicle transport defects observed in ashen mice. Proc Natl Acad Sci U S A 97, 7933-7938 doi:10.1073/pnas.140212797 (2000).
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 7933-7938
-
-
Wilson, S.M.1
-
27
-
-
84875360347
-
Distinctive subdomains in the resorbing surface of osteoclasts
-
Szewczyk, K. A., Fuller, K. & Chambers, T. J. Distinctive subdomains in the resorbing surface of osteoclasts. PLoS One 8, e60285, doi:10.1371/journal.pone.0060285 (2013).
-
(2013)
PLoS One
, vol.8
, pp. e60285
-
-
Szewczyk, K.A.1
Fuller, K.2
Chambers, T.J.3
-
28
-
-
84876329723
-
Vps35 loss promotes hyperresorptive osteoclastogenesis and osteoporosis via sustained RANKL signaling
-
Xia, W. F. et al. Vps35 loss promotes hyperresorptive osteoclastogenesis and osteoporosis via sustained RANKL signaling. J Cell Biol 200, 821-837, doi:10.1083/jcb.201207154 (2013).
-
(2013)
J Cell Biol
, vol.200
, pp. 821-837
-
-
Xia, W.F.1
-
29
-
-
84883446741
-
Regulation of osteoclasts by membrane-derived lipid mediators
-
Oikawa, T., Kuroda, Y. & Matsuo, K. Regulation of osteoclasts by membrane-derived lipid mediators. Cell Mol Life Sci 70, 3341-3353, doi:10.1007/s00018-012-1238-4 (2013).
-
(2013)
Cell Mol Life Sci
, vol.70
, pp. 3341-3353
-
-
Oikawa, T.1
Kuroda, Y.2
Matsuo, K.3
-
30
-
-
33947538274
-
Rab27a regulates phagosomal pH and NADPH oxidase recruitment to dendritic cell phagosomes
-
Jancic, C. et al. Rab27a regulates phagosomal pH and NADPH oxidase recruitment to dendritic cell phagosomes. Nat Cell Biol 9, 367-378, doi:10.1038/ncb1552 (2007).
-
(2007)
Nat Cell Biol
, vol.9
, pp. 367-378
-
-
Jancic, C.1
-
31
-
-
84856832052
-
NADPH oxidase is internalized by clathrin-coated pits and localizes to a Rab27A/B GTPase-regulated secretory compartment in activated macrophages
-
Ejlerskov, P. et al. NADPH oxidase is internalized by clathrin-coated pits and localizes to a Rab27A/B GTPase-regulated secretory compartment in activated macrophages. J Biol Chem 287, 4835-4852, doi:10.1074/jbc.M111.293696 (2012).
-
(2012)
J Biol Chem
, vol.287
, pp. 4835-4852
-
-
Ejlerskov, P.1
-
32
-
-
79953130385
-
Rab27a negatively regulates phagocytosis by prolongation of the actin-coating stage around phagosomes
-
Yokoyama, K. et al. Rab27a negatively regulates phagocytosis by prolongation of the actin-coating stage around phagosomes. J Biol Chem 286, 5375-5382, doi:10.1074/jbc.M110.171702 (2011).
-
(2011)
J Biol Chem
, vol.286
, pp. 5375-5382
-
-
Yokoyama, K.1
-
33
-
-
77951709524
-
Rab27a and Rab27b regulate neutrophil azurophilic granule exocytosis and NADPH oxidase activity by independent mechanisms
-
Johnson, J. L. et al. Rab27a and Rab27b regulate neutrophil azurophilic granule exocytosis and NADPH oxidase activity by independent mechanisms. Traffic 11, 533-547, doi:10.1111/j.1600-0854.2009.01029.x (2010).
-
(2010)
Traffic
, vol.11
, pp. 533-547
-
-
Johnson, J.L.1
-
34
-
-
79953154054
-
Munc13-4 restricts motility of Rab27a-expressing vesicles to facilitate lipopolysaccharide-induced priming of exocytosis in neutrophils
-
Johnson, J. L., Hong, H., Monfregola, J., Kiosses, W. B. & Catz, S. D. Munc13-4 restricts motility of Rab27a-expressing vesicles to facilitate lipopolysaccharide-induced priming of exocytosis in neutrophils. J Biol Chem 286, 5647-5656, doi:10.1074/jbc.M110.184762 (2011).
-
(2011)
J Biol Chem
, vol.286
, pp. 5647-5656
-
-
Johnson, J.L.1
Hong, H.2
Monfregola, J.3
Kiosses, W.B.4
Catz, S.D.5
-
35
-
-
84888802805
-
An essential role for Rab27a GTPase in eosinophil exocytosis
-
Kim, J. D. et al. An essential role for Rab27a GTPase in eosinophil exocytosis. J Leukoc Biol 94, 1265-1274, doi:10.1189/jlb.0812431 (2013).
-
(2013)
J Leukoc Biol
, vol.94
, pp. 1265-1274
-
-
Kim, J.D.1
-
36
-
-
4744350042
-
Involvement of Rab27 in antigen-induced histamine release from rat basophilic leukemia 2H3 cells
-
Goishi, K., Mizuno, K., Nakanishi, H. & Sasaki, T. Involvement of Rab27 in antigen-induced histamine release from rat basophilic leukemia 2H3 cells. Biochem Biophys Res Commun 324, 294-301, doi:10.1016/j.bbrc.2004.09.050 (2004).
-
(2004)
Biochem Biophys Res Commun
, vol.324
, pp. 294-301
-
-
Goishi, K.1
Mizuno, K.2
Nakanishi, H.3
Sasaki, T.4
-
37
-
-
0037936890
-
From lysosomes to the plasma membrane: Localization of vacuolar-type H+ -ATPase with the a3 isoform during osteoclast differentiation
-
Toyomura, T. et al. From lysosomes to the plasma membrane: localization of vacuolar-type H+ -ATPase with the a3 isoform during osteoclast differentiation. J Biol Chem 278, 22023-22030, doi:10.1074/jbc.M302436200 (2003).
-
(2003)
J Biol Chem
, vol.278
, pp. 22023-22030
-
-
Toyomura, T.1
-
38
-
-
0035914465
-
Downregulation of small GTPase Rab7 impairs osteoclast polarization and bone resorption
-
Zhao, H., Laitala-Leinonen, T., Parikka, V. & Vaananen, H. K. Downregulation of small GTPase Rab7 impairs osteoclast polarization and bone resorption. J Biol Chem 276, 39295-39302, doi:10.1074/jbc.M010999200 (2001).
-
(2001)
J Biol Chem
, vol.276
, pp. 39295-39302
-
-
Zhao, H.1
Laitala-Leinonen, T.2
Parikka, V.3
Vaananen, H.K.4
-
39
-
-
84865842066
-
Rab13 is upregulated during osteoclast differentiation and associates with small vesicles revealing polarized distribution in resorbing cells
-
Hirvonen, M. J. et al. Rab13 is upregulated during osteoclast differentiation and associates with small vesicles revealing polarized distribution in resorbing cells. J Histochem Cytochem 60, 537-549, doi:10.1369/0022155412448069 (2012).
-
(2012)
J Histochem Cytochem
, vol.60
, pp. 537-549
-
-
Hirvonen, M.J.1
-
40
-
-
84867070689
-
The collection of NFATc1-dependent transcripts in the osteoclast includes numerous genes non-essential to physiologic bone resorption
-
Charles, J. F. et al. The collection of NFATc1-dependent transcripts in the osteoclast includes numerous genes non-essential to physiologic bone resorption. Bone 51, 902-912, doi:10.1016/j.bone.2012.08.113 (2012).
-
(2012)
Bone
, vol.51
, pp. 902-912
-
-
Charles, J.F.1
-
41
-
-
79953042881
-
Rab27a and Rab27b are involved in stimulation-dependent RANKL release from secretory lysosomes in osteoblastic cells
-
Kariya, Y. et al. Rab27a and Rab27b are involved in stimulation-dependent RANKL release from secretory lysosomes in osteoblastic cells. J Bone Miner Res 26, 689-703, doi:10.1002/jbmr.268 (2011).
-
(2011)
J Bone Miner Res
, vol.26
, pp. 689-703
-
-
Kariya, Y.1
-
42
-
-
37648999717
-
Berberine inhibits RANKL-induced osteoclast formation and survival through suppressing the NF-kappaB and Akt pathways
-
Hu, J. P. et al. Berberine inhibits RANKL-induced osteoclast formation and survival through suppressing the NF-kappaB and Akt pathways. Eur J Pharmacol 580, 70-79, doi:10.1016/j.ejphar.2007.11.013 (2008).
-
(2008)
Eur J Pharmacol
, vol.580
, pp. 70-79
-
-
Hu, J.P.1
-
43
-
-
33847303003
-
Cathepsin E deficiency induces a novel form of lysosomal storage disorder showing the accumulation of lysosomal membrane sialoglycoproteins and the elevation of lysosomal pH in macrophages
-
Yanagawa, M. et al. Cathepsin E deficiency induces a novel form of lysosomal storage disorder showing the accumulation of lysosomal membrane sialoglycoproteins and the elevation of lysosomal pH in macrophages. J Biol Chem 282, 1851-1862, doi:10.1074/jbc.M604143200 (2007).
-
(2007)
J Biol Chem
, vol.282
, pp. 1851-1862
-
-
Yanagawa, M.1
-
44
-
-
0031978083
-
Fluorescence microscopic demonstration of cathepsin K activity as the major lysosomal cysteine proteinase in osteoclasts
-
Kamiya, T. et al. Fluorescence microscopic demonstration of cathepsin K activity as the major lysosomal cysteine proteinase in osteoclasts. J Biochem 123, 752-759 (1998).
-
(1998)
J Biochem
, vol.123
, pp. 752-759
-
-
Kamiya, T.1
-
45
-
-
20144373742
-
Rab27a mediates the tight docking of insulin granules onto the plasma membrane during glucose stimulation
-
Kasai, K. et al. Rab27a mediates the tight docking of insulin granules onto the plasma membrane during glucose stimulation. J Clin Invest 115, 388-396, doi:10.1172/JCI22955 (2005).
-
(2005)
J Clin Invest
, vol.115
, pp. 388-396
-
-
Kasai, K.1
-
46
-
-
84855554307
-
Suppression of RANKL-dependent heme oxygenase-1 is required for high mobility group box 1 release and osteoclastogenesis
-
Sakai, E. et al. Suppression of RANKL-dependent heme oxygenase-1 is required for high mobility group box 1 release and osteoclastogenesis. J Cell Biochem 113, 486-498, doi:10.1002/jcb.23372 (2012).
-
(2012)
J Cell Biochem
, vol.113
, pp. 486-498
-
-
Sakai, E.1
-
47
-
-
0346525140
-
U0126 and PD98059, specific inhibitors of MEK, accelerate differentiation of RAW264.7 cells into osteoclast-like cells
-
Hotokezaka, H. et al. U0126 and PD98059, specific inhibitors of MEK, accelerate differentiation of RAW264.7 cells into osteoclast-like cells. J Biol Chem 277, 47366-47372, doi:10.1074/jbc.M208284200 (2002).
-
(2002)
J Biol Chem
, vol.277
, pp. 47366-47372
-
-
Hotokezaka, H.1
-
48
-
-
84877623497
-
Fisetin inhibits osteoclastogenesis through prevention of RANKL-induced ROS production by Nrf2-mediated up-regulation of phase II antioxidant enzymes
-
Sakai, E. et al. Fisetin inhibits osteoclastogenesis through prevention of RANKL-induced ROS production by Nrf2-mediated up-regulation of phase II antioxidant enzymes. J Pharmacol Sci 121, 288-298, doi:10.1254/jphs.12243FP (2013).
-
(2013)
J Pharmacol Sci
, vol.121
, pp. 288-298
-
-
Sakai, E.1
|