Cell-autonomous activation of Hedgehog signaling inhibits brown adipose tissue development

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 16, 2015, Pages 5069-5074

  Nosavanh, LaGina ^a,c   Yu, Da Hai ^a   Jaehnig, Eric J ^b   Tong, Qiang ^a   Shen, Lanlan ^a   Chen, Miao Hsueh ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Harmony School of Innovation   (United States)

Author keywords

Brown adipose tissue; Cell fate; Hedgehog signaling

Indexed keywords

ADIPOCYTE PROTEIN 2; ADIPONECTIN; CCAAT ENHANCER BINDING PROTEIN ALPHA; CCAAT ENHANCER BINDING PROTEIN BETA; CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR 2; CRE RECOMBINASE; DESMIN; FAT DROPLET; GLUCOSE TRANSPORTER 4; MYOD1 PROTEIN; MYOGENIN; MYOSIN HEAVY CHAIN; NECDIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1; WNT10B PROTEIN;

ADIPOGENESIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BROWN ADIPOCYTE; BROWN ADIPOSE TISSUE; CELL ACTIVATION; CELL DIFFERENTIATION; CELL FATE; CELL PROLIFERATION; CELL STRUCTURE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; EMBRYO; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROADIPOCYTE; PROMOTER REGION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; UPREGULATION; ANIMAL; CYTOLOGY; EMBRYOLOGY; EUKARYOTIC FLAGELLUM; GENETICS; METABOLISM;

ERINACEIDAE;

ADIPOCYTES, BROWN; ADIPOSE TISSUE, BROWN; ANIMALS; CELL DIFFERENTIATION; CILIA; COUP TRANSCRIPTION FACTOR II; HEDGEHOG PROTEINS; MICE; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84928137395     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1420978112     Document Type: Article

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