-
1
-
-
0030006070
-
Clonal selection and learning in the antibody system
-
Rajewsky, K. Clonal selection and learning in the antibody system. Nature 381, 751-758 (1996).
-
(1996)
Nature
, vol.381
, pp. 751-758
-
-
Rajewsky, K.1
-
2
-
-
77954913409
-
Control systems and decision making for antibody production
-
Goodnow, C. C., Vinuesa, C. G., Randall, K. L., Mackay, F. & Brink, R. Control systems and decision making for antibody production. Nat. Immunol. 11, 681-688 (2010).
-
(2010)
Nat. Immunol.
, vol.11
, pp. 681-688
-
-
Goodnow, C.C.1
Vinuesa, C.G.2
Randall, K.L.3
Mackay, F.4
Brink, R.5
-
3
-
-
34250212629
-
The transcriptional regulation of B cell lineage commitment
-
Nutt, S. L. & Kee, B. L. The transcriptional regulation of B cell lineage commitment. Immunity 26, 715-725 (2007).
-
(2007)
Immunity
, vol.26
, pp. 715-725
-
-
Nutt, S.L.1
Kee, B.L.2
-
4
-
-
77951259076
-
Transcription control of early B cell differentiation
-
Mandel, E. M. & Grosschedl, R. Transcription control of early B cell differentiation. Curr. Opin. Immunol. 22, 161-167 (2010).
-
(2010)
Curr. Opin. Immunol.
, vol.22
, pp. 161-167
-
-
Mandel, E.M.1
Grosschedl, R.2
-
5
-
-
58149085504
-
MicroRNA control in the immune system: Basic principles
-
Xiao, C. & Rajewsky, K. MicroRNA control in the immune system: basic principles. Cell 136, 26-36 (2009).
-
(2009)
Cell
, vol.136
, pp. 26-36
-
-
Xiao, C.1
Rajewsky, K.2
-
6
-
-
84875760707
-
Regulation of B-cell development and function by microRNAs
-
de Yebenes, V. G., Bartolome-Izquierdo, N. & Ramiro, A. R. Regulation of B-cell development and function by microRNAs. Immunol. Rev. 253, 25-39 (2013).
-
(2013)
Immunol. Rev.
, vol.253
, pp. 25-39
-
-
De Yebenes, V.G.1
Bartolome-Izquierdo, N.2
Ramiro, A.R.3
-
7
-
-
8144225486
-
MicroRNA genes are transcribed by RNA polymerase II
-
Lee, Y. et al. MicroRNA genes are transcribed by RNA polymerase II. EMBO J. 23, 4051-4060 (2004).
-
(2004)
EMBO J.
, vol.23
, pp. 4051-4060
-
-
Lee, Y.1
-
8
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee, Y. et al. The nuclear RNase III Drosha initiates microRNA processing. Nature 425, 415-419 (2003).
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
-
9
-
-
0035800521
-
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
-
Hutvagner, G. et al. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293, 834-838 (2001).
-
(2001)
Science
, vol.293
, pp. 834-838
-
-
Hutvagner, G.1
-
10
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis, B. P., Burge, C. B. & Bartel, D. P. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120, 15-20 (2005).
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
11
-
-
39749101294
-
Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage
-
Koralov, S. B. et al. Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage. Cell 132, 860-874 (2008).
-
(2008)
Cell
, vol.132
, pp. 860-874
-
-
Koralov, S.B.1
-
12
-
-
78650196925
-
MicroRNAs prevent the generation of autoreactive antibodies
-
Belver, L., de Yebenes, V. G. & Ramiro, A. R. MicroRNAs prevent the generation of autoreactive antibodies. Immunity 33, 713-722 (2010).
-
(2010)
Immunity
, vol.33
, pp. 713-722
-
-
Belver, L.1
De Yebenes, V.G.2
Ramiro, A.R.3
-
13
-
-
84856068405
-
The RNase III enzyme Dicer is essential for germinal center B-cell formation
-
Xu, S., Guo, K., Zeng, Q., Huo, J. & Lam, K. P. The RNase III enzyme Dicer is essential for germinal center B-cell formation. Blood 119, 767-776 (2012).
-
(2012)
Blood
, vol.119
, pp. 767-776
-
-
Xu, S.1
Guo, K.2
Zeng, Q.3
Huo, J.4
Lam, K.P.5
-
14
-
-
2342449399
-
Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma
-
Ota, A. et al. Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma. Cancer Res. 64, 3087-3095 (2004).
-
(2004)
Cancer Res.
, vol.64
, pp. 3087-3095
-
-
Ota, A.1
-
15
-
-
27644570319
-
A microRNA cluster as a target of genomic amplification in malignant lymphoma
-
Tagawa, H. & Seto, M. A microRNA cluster as a target of genomic amplification in malignant lymphoma. Leukemia 19, 2013-2016 (2005).
-
(2005)
Leukemia
, vol.19
, pp. 2013-2016
-
-
Tagawa, H.1
Seto, M.2
-
16
-
-
20444467290
-
A microRNA polycistron as a potential human oncogene
-
He, L. et al. A microRNA polycistron as a potential human oncogene. Nature 435, 828-833 (2005).
-
(2005)
Nature
, vol.435
, pp. 828-833
-
-
He, L.1
-
17
-
-
84883310620
-
MicroRNA-17 B92 plays a causative role in lymphomagenesis by coordinating multiple oncogenic pathways
-
Jin, H. Y. et al. MicroRNA-17 B92 plays a causative role in lymphomagenesis by coordinating multiple oncogenic pathways. EMBO J. 32, 2377-2391 (2013).
-
(2013)
EMBO J.
, vol.32
, pp. 2377-2391
-
-
Jin, H.Y.1
-
18
-
-
39749143354
-
Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters
-
Ventura, A. et al. Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell 132, 875-886 (2008).
-
(2008)
Cell
, vol.132
, pp. 875-886
-
-
Ventura, A.1
-
19
-
-
33751530065
-
Plasma cell S1P1 expression determines secondary lymphoid organ retention versus bone marrow tropism
-
Kabashima, K. et al. Plasma cell S1P1 expression determines secondary lymphoid organ retention versus bone marrow tropism. J. Exp. Med. 203, 2683-2690 (2006).
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2683-2690
-
-
Kabashima, K.1
-
20
-
-
66049120992
-
Ikaros controls isotype selection during immunoglobulin class switch recombination
-
Sellars, M., Reina-San-Martin, B., Kastner, P. & Chan, S. Ikaros controls isotype selection during immunoglobulin class switch recombination. J. Exp. Med. 206, 1073-1087 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1073-1087
-
-
Sellars, M.1
Reina-San-Martin, B.2
Kastner, P.3
Chan, S.4
-
21
-
-
79959714872
-
A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL)
-
Mavrakis, K. J. et al. A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL). Nat. Genet. 43, 673-678 (2011).
-
(2011)
Nat. Genet.
, vol.43
, pp. 673-678
-
-
Mavrakis, K.J.1
-
22
-
-
34250694086
-
Vagaries of conditional gene targeting
-
Schmidt-Supprian, M. & Rajewsky, K. Vagaries of conditional gene targeting. Nat. Immunol. 8, 665-668 (2007).
-
(2007)
Nat. Immunol.
, vol.8
, pp. 665-668
-
-
Schmidt-Supprian, M.1
Rajewsky, K.2
-
23
-
-
78650600361
-
The double life of a B-1 cell: Self-reactivity selects for protective effector functions
-
Baumgarth, N. The double life of a B-1 cell: self-reactivity selects for protective effector functions. Nat. Rev. Immunol. 11, 34-46 (2011).
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 34-46
-
-
Baumgarth, N.1
-
25
-
-
44749089614
-
Plasma cell differentiation and survival
-
Tarlinton, D., Radbruch, A., Hiepe, F. & Dorner, T. Plasma cell differentiation and survival. Curr. Opin. Immunol. 20, 162-169 (2008).
-
(2008)
Curr. Opin. Immunol.
, vol.20
, pp. 162-169
-
-
Tarlinton, D.1
Radbruch, A.2
Hiepe, F.3
Dorner, T.4
-
26
-
-
8644227902
-
The role of CXCR4 in maintaining peripheral B cell compartments and humoral immunity
-
Nie, Y. et al. The role of CXCR4 in maintaining peripheral B cell compartments and humoral immunity. J. Exp. Med. 200, 1145-1156 (2004).
-
(2004)
J. Exp. Med.
, vol.200
, pp. 1145-1156
-
-
Nie, Y.1
-
27
-
-
84859385704
-
Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs
-
Cyster, J. G. & Schwab, S. R. Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs. Annu. Rev. Immunol. 30, 69-94 (2012).
-
(2012)
Annu. Rev. Immunol.
, vol.30
, pp. 69-94
-
-
Cyster, J.G.1
Schwab, S.R.2
-
28
-
-
0032525049
-
FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homing
-
Chiba, K. et al. FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homing. J. Immunol. 160, 5037-5044 (1998).
-
(1998)
J. Immunol.
, vol.160
, pp. 5037-5044
-
-
Chiba, K.1
-
29
-
-
0037077308
-
The immune modulator FTY720 targets sphingosine 1-phosphate receptors
-
Brinkmann, V. et al. The immune modulator FTY720 targets sphingosine 1-phosphate receptors. J. Biol. Chem. 277, 21453-21457 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21453-21457
-
-
Brinkmann, V.1
-
30
-
-
84857355337
-
Possible allelic structure of IgG2a and IgG2c in mice
-
Zhang, Z., Goldschmidt, T. & Salter, H. Possible allelic structure of IgG2a and IgG2c in mice. Mol. Immunol. 50, 169-171 (2012).
-
(2012)
Mol. Immunol.
, vol.50
, pp. 169-171
-
-
Zhang, Z.1
Goldschmidt, T.2
Salter, H.3
-
31
-
-
42649123314
-
Mechanism and regulation of class switch recombination
-
Stavnezer, J., Guikema, J. E. & Schrader, C. E. Mechanism and regulation of class switch recombination. Annu. Rev. Immunol. 26, 261-292 (2008).
-
(2008)
Annu. Rev. Immunol.
, vol.26
, pp. 261-292
-
-
Stavnezer, J.1
Guikema, J.E.2
Schrader, C.E.3
-
32
-
-
0346362489
-
Transcription-coupled events associating with immunoglobulin switch region chromatin
-
Nambu, Y. et al. Transcription-coupled events associating with immunoglobulin switch region chromatin. Science 302, 2137-2140 (2003).
-
(2003)
Science
, vol.302
, pp. 2137-2140
-
-
Nambu, Y.1
-
33
-
-
31344445404
-
AID-dependent histone acetylation is detected in immunoglobulin S regions
-
Wang, L., Whang, N., Wuerffel, R. & Kenter, A. L. AID-dependent histone acetylation is detected in immunoglobulin S regions. J. Exp. Med. 203, 215-226 (2006).
-
(2006)
J. Exp. Med.
, vol.203
, pp. 215-226
-
-
Wang, L.1
Whang, N.2
Wuerffel, R.3
Kenter, A.L.4
-
34
-
-
0027018352
-
IgG subclasses in systemic lupus erythematosus and other autoimmune rheumatic diseases
-
Blanco, F. et al. IgG subclasses in systemic lupus erythematosus and other autoimmune rheumatic diseases. Lupus 1, 391-399 (1992).
-
(1992)
Lupus
, vol.1
, pp. 391-399
-
-
Blanco, F.1
-
35
-
-
0025871761
-
Subclasses of IgG anticardiolipin antibodies in patients with systemic lupus erythematosus
-
Tiikkainen, U., Wangel, A., Appleton, S. L. & Arthur, D. Subclasses of IgG anticardiolipin antibodies in patients with systemic lupus erythematosus. Scand. J. Immunol. 34, 265-271 (1991).
-
(1991)
Scand. J. Immunol.
, vol.34
, pp. 265-271
-
-
Tiikkainen, U.1
Wangel, A.2
Appleton, S.L.3
Arthur, D.4
-
36
-
-
2442433618
-
Pathogenic roles of B cells in human autoimmunity; insights from the clinic
-
Martin, F. & Chan, A. C. Pathogenic roles of B cells in human autoimmunity; insights from the clinic. Immunity 20, 517-527 (2004).
-
(2004)
Immunity
, vol.20
, pp. 517-527
-
-
Martin, F.1
Chan, A.C.2
-
37
-
-
39549111438
-
Anti-DNA antibodies in the pathogenesis of lupus nephritis - The emerging mechanisms
-
Yung, S. & Chan, T. M. Anti-DNA antibodies in the pathogenesis of lupus nephritis - the emerging mechanisms. Autoimmun. Rev. 7, 317-321 (2008).
-
(2008)
Autoimmun. Rev.
, vol.7
, pp. 317-321
-
-
Yung, S.1
Chan, T.M.2
-
38
-
-
34447624878
-
B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity
-
Pao, L. I. et al. B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity. Immunity 27, 35-48 (2007).
-
(2007)
Immunity
, vol.27
, pp. 35-48
-
-
Pao, L.I.1
-
39
-
-
39749163245
-
Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes
-
Xiao, C. et al. Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes. Nat. Immunol. 9, 405-414 (2008).
-
(2008)
Nat. Immunol.
, vol.9
, pp. 405-414
-
-
Xiao, C.1
-
40
-
-
77953915915
-
Regulation of microRNA expression and abundance during lymphopoiesis
-
Kuchen, S. et al. Regulation of microRNA expression and abundance during lymphopoiesis. Immunity 32, 828-839 (2010).
-
(2010)
Immunity
, vol.32
, pp. 828-839
-
-
Kuchen, S.1
-
41
-
-
0033806822
-
Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survival
-
Sze, D. M., Toellner, K. M., Garcia,d, V., Taylor, D. R. & MacLennan, I. C. Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survival. J. Exp. Med. 192, 813-821 (2000).
-
(2000)
J. Exp. Med.
, vol.192
, pp. 813-821
-
-
Sze, D.M.1
Toellner, K.M.2
Garcia, D.V.3
Taylor, D.R.4
MacLennan, I.C.5
-
42
-
-
0042591464
-
Plasma cell survival is mediated by synergistic effects of cytokines and adhesion-dependent signals
-
Cassese, G. et al. Plasma cell survival is mediated by synergistic effects of cytokines and adhesion-dependent signals. J. Immunol. 171, 1684-1690 (2003).
-
(2003)
J. Immunol.
, vol.171
, pp. 1684-1690
-
-
Cassese, G.1
-
43
-
-
0037108354
-
The role of bone marrow-derived stromal cells in the maintenance of plasma cell longevity
-
Minges Wols, H. A., Underhill, G. H., Kansas, G. S. & Witte, P. L. The role of bone marrow-derived stromal cells in the maintenance of plasma cell longevity. J. Immunol. 169, 4213-4221 (2002).
-
(2002)
J. Immunol.
, vol.169
, pp. 4213-4221
-
-
Minges Wols, H.A.1
Underhill, G.H.2
Kansas, G.S.3
Witte, P.L.4
-
44
-
-
84864137558
-
Unique contribution of IRF-5-Ikaros axis to the B-cell IgG2a response
-
Fang, C. M. et al. Unique contribution of IRF-5-Ikaros axis to the B-cell IgG2a response. Genes Immun. 13, 421-430 (2012).
-
(2012)
Genes Immun.
, vol.13
, pp. 421-430
-
-
Fang, C.M.1
-
45
-
-
77953368347
-
Contribution of IRF5 in B cells to the development of murine SLE-like disease through its transcriptional control of the IgG2a locus
-
Savitsky, D. A., Yanai, H., Tamura, T., Taniguchi, T. & Honda, K. Contribution of IRF5 in B cells to the development of murine SLE-like disease through its transcriptional control of the IgG2a locus. Proc. Natl Acad. Sci. USA 107, 10154-10159 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 10154-10159
-
-
Savitsky, D.A.1
Yanai, H.2
Tamura, T.3
Taniguchi, T.4
Honda, K.5
-
46
-
-
0023108206
-
IgG2a restriction of murine antibodies elicited by viral infections
-
Coutelier, J. P., van der Logt, J. T., Heessen, F. W., Warnier, G. & Van Snick, J. IgG2a restriction of murine antibodies elicited by viral infections. J. Exp. Med. 165, 64-69 (1987).
-
(1987)
J. Exp. Med.
, vol.165
, pp. 64-69
-
-
Coutelier, J.P.1
Van Der Logt, J.T.2
Heessen, F.W.3
Warnier, G.4
Van Snick, J.5
-
47
-
-
0021967361
-
Importance of immunoglobulin isotype in human antibody-dependent, cell-mediated cytotoxicity directed by murine monoclonal antibodies
-
Kipps, T. J., Parham, P., Punt, J. & Herzenberg, L. A. Importance of immunoglobulin isotype in human antibody-dependent, cell-mediated cytotoxicity directed by murine monoclonal antibodies. J. Exp. Med. 161, 1-17 (1985).
-
(1985)
J. Exp. Med.
, vol.161
, pp. 1-17
-
-
Kipps, T.J.1
Parham, P.2
Punt, J.3
Herzenberg, L.A.4
-
48
-
-
28544449847
-
Divergent immunoglobulin g subclass activity through selective Fc receptor binding
-
Nimmerjahn, F. & Ravetch, J. V. Divergent immunoglobulin g subclass activity through selective Fc receptor binding. Science 310, 1510-1512 (2005).
-
(2005)
Science
, vol.310
, pp. 1510-1512
-
-
Nimmerjahn, F.1
Ravetch, J.V.2
-
49
-
-
0034678446
-
Markedly different pathogenicity of four immunoglobulin G isotype-switch variants of an antierythrocyte autoantibody is based on their capacity to interact in vivo with the low-affinity Fcgamma receptor III
-
Fossati-Jimack, L. et al. Markedly different pathogenicity of four immunoglobulin G isotype-switch variants of an antierythrocyte autoantibody is based on their capacity to interact in vivo with the low-affinity Fcgamma receptor III. J. Exp. Med. 191, 1293-1302 (2000).
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1293-1302
-
-
Fossati-Jimack, L.1
-
50
-
-
80053345544
-
GRK2-dependent S1PR1 desensitization is required for lymphocytes to overcome their attraction to blood
-
Arnon, T. I. et al. GRK2-dependent S1PR1 desensitization is required for lymphocytes to overcome their attraction to blood. Science 333, 1898-1903 (2011).
-
(2011)
Science
, vol.333
, pp. 1898-1903
-
-
Arnon, T.I.1
-
51
-
-
17144439800
-
The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
-
Ye, B. H. et al. The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation. Nat. Genet. 16, 161-170 (1997).
-
(1997)
Nat. Genet.
, vol.16
, pp. 161-170
-
-
Ye, B.H.1
-
52
-
-
65449131255
-
Phospholipase Cgamma2 is critical for Dectin-1-mediated Ca2+ flux and cytokine production in dendritic cells
-
Xu, S., Huo, J., Lee, K. G., Kurosaki, T. & Lam, K. P. Phospholipase Cgamma2 is critical for Dectin-1-mediated Ca2+ flux and cytokine production in dendritic cells. J. Biol. Chem. 284, 7038-7046 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 7038-7046
-
-
Xu, S.1
Huo, J.2
Lee, K.G.3
Kurosaki, T.4
Lam, K.P.5
-
53
-
-
77950862656
-
Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET
-
Matsui, T. et al. Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET. Nature 464, 927-931 (2010).
-
(2010)
Nature
, vol.464
, pp. 927-931
-
-
Matsui, T.1
|