NOTCH1 regulates matrix gla protein and calcification gene networks in human valve endothelium

Journal of Molecular and Cellular Cardiology

Volumn 84, Issue , 2015, Pages 13-23

  White, Mark P ^a   Theodoris, Christina V ^a   Liu, Lei ^a   Collins, William J ^a   Blue, Kathleen W ^a   Lee, Joon Ho ^b   Meng, Xianzhong ^b   Robbins, Robert C ^c   Ivey, Kathryn N ^a   Srivastava, Deepak ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Matrix gla protein; NOTCH signaling; NOTCH1; Valve calcification; Valve endothelium

Indexed keywords

BONE MORPHOGENETIC PROTEIN; CALCIUM BINDING PROTEIN; MATRIX GLA PROTEIN; NOTCH1 RECEPTOR; UNCLASSIFIED DRUG; DNA; PROTEIN BINDING; SCLEROPROTEIN;

AORTA VALVE; AORTIC VALVE ENDOTHELIUM; ARTICLE; BINDING AFFINITY; CALCIFICATION; CONTROLLED STUDY; DOWN REGULATION; ENCHONDRAL OSSIFICATION; ENDOTHELIUM; GENE; GENE FUNCTION; GENE REGULATORY NETWORK; GENE SILENCING; GJA5 GENE; HUMAN; HUMAN CELL; MGP GENE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; RNA SEQUENCE; SHEAR STRESS; SIGNAL TRANSDUCTION; VALVULAR CALCIFICATION; VALVULAR HEART DISEASE; AORTA VALVE STENOSIS; CALCINOSIS; CHROMATIN IMMUNOPRECIPITATION; CLUSTER ANALYSIS; ENDOTHELIUM CELL; ENHANCER REGION; FLOW KINETICS; GENE EXPRESSION REGULATION; GENETICS; HUMAN GENOME; MECHANICAL STRESS; METABOLISM; PATHOLOGY; SEQUENCE ANALYSIS; VASCULAR ENDOTHELIUM;

AORTIC VALVE; AORTIC VALVE STENOSIS; CALCINOSIS; CALCIUM-BINDING PROTEINS; CHROMATIN IMMUNOPRECIPITATION; CLUSTER ANALYSIS; DNA; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; ENHANCER ELEMENTS, GENETIC; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; GENOME, HUMAN; HUMANS; PROTEIN BINDING; RECEPTOR, NOTCH1; RHEOLOGY; SEQUENCE ANALYSIS, RNA; SIGNAL TRANSDUCTION; STRESS, MECHANICAL;

EID: 84928104278     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2015.04.006     Document Type: Article

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