Hemodynamic Environments from Opposing Sides of Human Aortic Valve Leaflets Evoke Distinct Endothelial Phenotypes in Vitro

Cardiovascular Engineering

Volumn 10, Issue 1, 2010, Pages 5-11

  Weinberg, Eli J ^a,b   MacK, Peter J ^b,c,d   Schoen, Frederick J ^c,d   García Cardeña, Guillermo ^c   Kaazempur Mofrad, Mohammad R ^a  

^a University of California at Berkeley   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

Author keywords

Aortic valve; Calcific aortic stenosis; Cell mechanics and mechanotransduction; Endothelial mechanotransduction; Shear stress; Valvular disease

Indexed keywords

KRUPPEL LIKE FACTOR 2; MONOCYTE CHEMOTACTIC PROTEIN 1; NEPHROBLASTOMA OVEREXPRESSED PROTEIN;

ANATOMICAL VARIATION; AORTA STENOSIS; AORTA VALVE; ARTICLE; CALCIFICATION; CONTROLLED STUDY; DISEASE COURSE; ENDOTHELIUM CELL; FINITE ELEMENT ANALYSIS; FLOW MEASUREMENT; HEART CYCLE; HEART HEMODYNAMICS; HEART MOVEMENT; HEMODYNAMIC MONITORING; HUMAN; HUMAN CELL; HYPOTHESIS; IN VITRO STUDY; MATHEMATICAL MODEL; MECHANOTRANSDUCTION; PHENOTYPIC VARIATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SHEAR STRESS; WAVEFORM;

AORTIC VALVE; CELLS, CULTURED; COMPUTER SIMULATION; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION; HUMANS; MECHANOTRANSDUCTION, CELLULAR; MODELS, CARDIOVASCULAR; PHENOTYPE; SHEAR STRENGTH;

EID: 77949655921     PISSN: 15678822     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10558-009-9089-9     Document Type: Article

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