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Volumn 7, Issue 4, 2015, Pages 2440-2455

Hepatoprotective effect of herb formula KIOM2012H against nonalcoholic fatty liver disease

Author keywords

Fatty acid; Herbal medicine; Lipid; Nonalcoholic fatty liver disease

Indexed keywords

ADIPOPHILIN; ALANINE AMINOTRANSFERASE; CD36 ANTIGEN; FATTY ACID; FATTY ACID SYNTHASE; HERBACEOUS AGENT; KIOM2012H AGENT; PERILIPIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; TRIACYLGLYCEROL; UBIQUITIN C; UNCLASSIFIED DRUG; PLANT MEDICINAL PRODUCT;

EID: 84927949136     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu7042440     Document Type: Article
Times cited : (12)

References (38)
  • 3
    • 79957449923 scopus 로고    scopus 로고
    • Changes in the prevalence of the most common causes of chronic liver diseases in the United States from 1988 to 2008. Clin. Gastroenterol
    • Younossi, Z.M.; Stepanova, M.; Afendy, M.; Fang, Y.; Younossi, Y.; Mir, H.; Srishord, M. Changes in the prevalence of the most common causes of chronic liver diseases in the United States from 1988 to 2008. Clin. Gastroenterol. Hepatol. 2011, 9, 524-530.
    • (2011) Hepatol , vol.9 , pp. 524-530
    • Younossi, Z.M.1    Stepanova, M.2    Afendy, M.3    Fang, Y.4    Younossi, Y.5    Mir, H.6    Srishord, M.7
  • 5
    • 84922622191 scopus 로고    scopus 로고
    • A concise review of non-alcoholic fatty liver disease
    • Than, N.N.; Newsome, P.N. A concise review of non-alcoholic fatty liver disease. Atherosclerosis 2015, 239, 192-202.
    • (2015) Atherosclerosis , vol.239 , pp. 192-202
    • Than, N.N.1    Newsome, P.N.2
  • 6
    • 18244382304 scopus 로고    scopus 로고
    • Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J. Clin
    • Donnelly, K.L.; Smith, C.I.; Schwarzenberg, S.J.; Jessurun, J.; Boldt, M.D.; Parks, E.J. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J. Clin. Investig. 2005, 115, 1343-1351.
    • (2005) Investig , vol.115 , pp. 1343-1351
    • Donnelly, K.L.1    Smith, C.I.2    Schwarzenberg, S.J.3    Jessurun, J.4    Boldt, M.D.5    Parks, E.J.6
  • 7
    • 84455162004 scopus 로고    scopus 로고
    • Serum Bcl-2 concentrations in overweight-obese subjects with nonalcoholic fatty liver disease. World J
    • Tarantino, G.; Scopacasa, F.; Colao, A.; Capone, D.; Tarantino, M.; Grimaldi, E.; Savastano, S. Serum Bcl-2 concentrations in overweight-obese subjects with nonalcoholic fatty liver disease. World J. Gastroenterol. 2011, 17, 5280-5288.
    • (2011) Gastroenterol , vol.17 , pp. 5280-5288
    • Tarantino, G.1    Scopacasa, F.2    Colao, A.3    Capone, D.4    Tarantino, M.5    Grimaldi, E.6    Savastano, S.7
  • 8
    • 32844458032 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in NASH: Causes, consequences and possible means to prevent it
    • Begriche, K.; Igoudjil, A.; Pessayre, D.; Fromenty, B. Mitochondrial dysfunction in NASH: Causes, consequences and possible means to prevent it. Mitochondrion 2006, 6, 1-28.
    • (2006) Mitochondrion , vol.6 , pp. 1-28
    • Begriche, K.1    Igoudjil, A.2    Pessayre, D.3    Fromenty, B.4
  • 9
    • 79955700474 scopus 로고    scopus 로고
    • Circulating levels of cytochrome C, gamma-glutamyl transferase, triglycerides and unconjugated bilirubin in overweight/obese patients with non-alcoholic fatty liver disease
    • Tarantino, G.; Colao, A.; Capone, D.; Conca, P.; Tarantino, M.; Grimaldi, E.; Chianese, D.; Finelli, C.; Contaldo, F.; Scopacasa, F.; et al. Circulating levels of cytochrome C, gamma-glutamyl transferase, triglycerides and unconjugated bilirubin in overweight/obese patients with non-alcoholic fatty liver disease. J. Biol. Regul. Homeost. Agents 2011, 25, 47-56.
    • (2011) J. Biol. Regul. Homeost. Agents , vol.25 , pp. 47-56
    • Tarantino, G.1    Colao, A.2    Capone, D.3    Conca, P.4    Tarantino, M.5    Grimaldi, E.6    Chianese, D.7    Finelli, C.8    Contaldo, F.9    Scopacasa, F.10
  • 10
    • 18244387691 scopus 로고    scopus 로고
    • Contribution of adipose tissue and de novo lipogenesis to nonalcoholic fatty liver disease. J. Clin
    • Tamura, S.; Shimomura, I. Contribution of adipose tissue and de novo lipogenesis to nonalcoholic fatty liver disease. J. Clin. Investig. 2005, 115, 1139-1142.
    • (2005) Investig , vol.115 , pp. 1139-1142
    • Tamura, S.1    Shimomura, I.2
  • 11
    • 32944457064 scopus 로고    scopus 로고
    • Identification of arctigenin as an antitumor agent having the ability to eliminate the tolerance of cancer cells to nutrient starvation
    • Awale, S.; Lu, J.; Kalauni, S.K.; Kurashima, Y.; Tezuka, Y.; Kadota, S.; Esumi, H. Identification of arctigenin as an antitumor agent having the ability to eliminate the tolerance of cancer cells to nutrient starvation. Cancer Res. 2006, 66, 1751-1757.
    • (2006) Cancer Res , vol.66 , pp. 1751-1757
    • Awale, S.1    Lu, J.2    Kalauni, S.K.3    Kurashima, Y.4    Tezuka, Y.5    Kadota, S.6    Esumi, H.7
  • 12
    • 84877814354 scopus 로고    scopus 로고
    • Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages. Eur. J
    • Hyam, S.R.; Lee, I.A.; Gu, W.; Kim, K.A.; Jeong, J.J.; Jang, S.E.; Han, M.J.; Kim, D.H. Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages. Eur. J. Pharmacol. 2013, 708, 21-29.
    • (2013) Pharmacol , vol.708 , pp. 21-29
    • Hyam, S.R.1    Lee, I.A.2    Gu, W.3    Kim, K.A.4    Jeong, J.J.5    Jang, S.E.6    Han, M.J.7    Kim, D.H.8
  • 13
    • 84925494391 scopus 로고    scopus 로고
    • Protective effects of Arctium lappa L. roots against hydrogen peroxide-induced cell injury and potential mechanisms in SH-SY5Y cells
    • Tian, X.; Guo, L.P.; Hu, X.L.; Huang, J.; Fan, Y.H.; Ren, T.S.; Zhao, Q.C. Protective effects of Arctium lappa L. roots against hydrogen peroxide-induced cell injury and potential mechanisms in SH-SY5Y cells. Cell. Mol. Neurobiol. 2014, doi:10.1007/s10571-014-0129-7.
    • (2014) Cell. Mol. Neurobiol
    • Tian, X.1    Guo, L.P.2    Hu, X.L.3    Huang, J.4    Fan, Y.H.5    Ren, T.S.6    Zhao, Q.C.7
  • 14
    • 34250372588 scopus 로고    scopus 로고
    • In vitro and in vivo antiallergic effects of Glycyrrhiza glabra and its components
    • Shin, Y.W.; Bae, E.A.; Lee, B.; Lee, S.H.; Kim, J.A.; Kim, Y.S.; Kim, D.H. In vitro and in vivo antiallergic effects of Glycyrrhiza glabra and its components. Planta Med. 2007, 73, 257-261.
    • (2007) Planta Med , vol.73 , pp. 257-261
    • Shin, Y.W.1    Bae, E.A.2    Lee, B.3    Lee, S.H.4    Kim, J.A.5    Kim, Y.S.6    Kim, D.H.7
  • 15
    • 83355177774 scopus 로고    scopus 로고
    • Hexane/ethanol extract of Glycyrrhiza uralensis and its active compound isoangustone A induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells
    • Seon, M.R.; Park, S.Y.; Kwon, S.J.; Lim, S.S.; Choi, H.J.; Park, H.; Lim, D.Y.; Kim, J.S.; Lee, C.H.; Kim, J.; et al. Hexane/ethanol extract of Glycyrrhiza uralensis and its active compound isoangustone A induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells. J. Nutr. Biochem. 2012, 23, 85-92.
    • (2012) J. Nutr. Biochem , vol.23 , pp. 85-92
    • Seon, M.R.1    Park, S.Y.2    Kwon, S.J.3    Lim, S.S.4    Choi, H.J.5    Park, H.6    Lim, D.Y.7    Kim, J.S.8    Lee, C.H.9    Kim, J.10
  • 17
    • 84878278811 scopus 로고    scopus 로고
    • Antioxidant and anti-inflammatory activities of six flavonoids separated from licorice
    • Fu, Y.; Chen, J.; Li, Y.J.; Zheng, Y.F.; Li, P. Antioxidant and anti-inflammatory activities of six flavonoids separated from licorice. Food Chem. 2013, 141, 1063-1071.
    • (2013) Food Chem , vol.141 , pp. 1063-1071
    • Fu, Y.1    Chen, J.2    Li, Y.J.3    Zheng, Y.F.4    Li, P.5
  • 18
    • 44749092859 scopus 로고    scopus 로고
    • Glycyrrhizin surface-modified chitosan nanoparticles for hepatocyte-targeted delivery. Int. J
    • Lin, A.; Liu, Y.; Huang, Y.; Sun, J.; Wu, Z.; Zhang, X.; Ping, Q. Glycyrrhizin surface-modified chitosan nanoparticles for hepatocyte-targeted delivery. Int. J. Pharm. 2008, 359, 247-253.
    • (2008) Pharm , vol.359 , pp. 247-253
    • Lin, A.1    Liu, Y.2    Huang, Y.3    Sun, J.4    Wu, Z.5    Zhang, X.6    Ping, Q.7
  • 19
    • 84907996107 scopus 로고    scopus 로고
    • Magnolia officinalis attenuates free fatty acid-induced lipogenesis via AMPK phosphorylation in hepatocytes. J
    • Seo, M.S.; Hong, S.W.; Yeon, S.H.; Kim, Y.M.; Um, K.A.; Kim, J.H.; Kim, H.J.; Chang, K.C.; Park, S.W. Magnolia officinalis attenuates free fatty acid-induced lipogenesis via AMPK phosphorylation in hepatocytes. J. Ethnopharmacol. 2014, 157, 140-148.
    • (2014) Ethnopharmacol , vol.157 , pp. 140-148
    • Seo, M.S.1    Hong, S.W.2    Yeon, S.H.3    Kim, Y.M.4    Um, K.A.5    Kim, J.H.6    Kim, H.J.7    Chang, K.C.8    Park, S.W.9
  • 20
    • 66249124259 scopus 로고    scopus 로고
    • Magnolia officinalis reverses alcoholic fatty liver by inhibiting the maturation of sterol regulatory element-binding protein-1c. J. Pharmacol
    • Yin, H.Q.; Je, Y.T.; Kim, Y.C.; Shin, Y.K.; Sung, S.; Lee, K.; Jeong, G.S.; Kim, Y.C.; Lee, B.H. Magnolia officinalis reverses alcoholic fatty liver by inhibiting the maturation of sterol regulatory element-binding protein-1c. J. Pharmacol. Sci. 2009, 109, 486-495.
    • (2009) Sci , vol.109 , pp. 486-495
    • Yin, H.Q.1    Je, Y.T.2    Kim, Y.C.3    Shin, Y.K.4    Sung, S.5    Lee, K.6    Jeong, G.S.7    Kim, Y.C.8    Lee, B.H.9
  • 21
    • 84908577554 scopus 로고    scopus 로고
    • Plasma cholesterol-lowering activity of gingerol- and shogaol-enriched extract is mediated by increasing sterol excretion
    • Lei, L.; Liu, Y.; Wang, X.; Jiao, R.; Ma, K.Y.; Li, Y.M.; Wang, L.; Man, S.W.; Sang, S.; Huang, Y.; et al. Plasma cholesterol-lowering activity of gingerol- and shogaol-enriched extract is mediated by increasing sterol excretion. J. Agric. Food Chem. 2014, 62, 10515-10521.
    • (2014) J. Agric. Food Chem , vol.62 , pp. 10515-10521
    • Lei, L.1    Liu, Y.2    Wang, X.3    Jiao, R.4    Ma, K.Y.5    Li, Y.M.6    Wang, L.7    Man, S.W.8    Sang, S.9    Huang, Y.10
  • 22
    • 64549145497 scopus 로고    scopus 로고
    • Protective effects of ethanolic extract of Zingiber officinale rhizome on the development of metabolic syndrome in high-fat diet-fed rats. Basic Clin. Pharmacol
    • Nammi, S.; Sreemantula, S.; Roufogalis, B.D. Protective effects of ethanolic extract of Zingiber officinale rhizome on the development of metabolic syndrome in high-fat diet-fed rats. Basic Clin. Pharmacol. Toxicol. 2009, 104, 366-373.
    • (2009) Toxicol , vol.104 , pp. 366-373
    • Nammi, S.1    Sreemantula, S.2    Roufogalis, B.D.3
  • 23
    • 0034011401 scopus 로고    scopus 로고
    • Ginger extract consumption reduces plasma cholesterol, inhibits LDL oxidation and attenuates development of atherosclerosis in atherosclerotic, apolipoprotein E-deficient mice. J
    • Fuhrman, B.; Rosenblat, M.; Hayek, T.; Coleman, R.; Aviram, M. Ginger extract consumption reduces plasma cholesterol, inhibits LDL oxidation and attenuates development of atherosclerosis in atherosclerotic, apolipoprotein E-deficient mice. J. Nutr. 2000, 130, 1124-1131.
    • (2000) Nutr , vol.130 , pp. 1124-1131
    • Fuhrman, B.1    Rosenblat, M.2    Hayek, T.3    Coleman, R.4    Aviram, M.5
  • 24
    • 84864913488 scopus 로고    scopus 로고
    • HRT, Herbal formula, induces G(2)/M cell cycle arrest and apoptosis via suppressing Akt signaling pathway in human colon cancer cells. Evid. Based Complement. Altern
    • Yim, N.H.; Cho, W.K.; Lee, J.H.; Jung, Y.P.; Yang, H.J.; Ma, J.Y. HRT, Herbal formula, induces G(2)/M cell cycle arrest and apoptosis via suppressing Akt signaling pathway in human colon cancer cells. Evid. Based Complement. Altern. Med. 2012, 2012, 871893, doi:10.1155/2012/871893.
    • (2012) Med , vol.2012
    • Yim, N.H.1    Cho, W.K.2    Lee, J.H.3    Jung, Y.P.4    Yang, H.J.5    Ma, J.Y.6
  • 25
    • 0021816546 scopus 로고
    • Spectrofluorometric studies of the lipid probe, Nile Red. J
    • Greenspan, P.; Fowler, S.D. Spectrofluorometric studies of the lipid probe, Nile Red. J. Lipid Res. 1985, 26, 781-789.
    • (1985) Lipid Res , vol.26 , pp. 781-789
    • Greenspan, P.1    Fowler, S.D.2
  • 26
  • 27
    • 33644797843 scopus 로고    scopus 로고
    • Glucagon and cAMP inhibit cholesterol 7α-hydroxylase (CYP7A1) gene expression in human hepatocytes: Discordant regulation of bile acid synthesis and gluconeogenesis
    • Song, K.H.; Chiang, J.Y. Glucagon and cAMP inhibit cholesterol 7α-hydroxylase (CYP7A1) gene expression in human hepatocytes: Discordant regulation of bile acid synthesis and gluconeogenesis. Hepatology 2006, 43, 117-125.
    • (2006) Hepatology , vol.43 , pp. 117-125
    • Song, K.H.1    Chiang, J.Y.2
  • 28
    • 66349125337 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease. J
    • Erickson, S.K. Nonalcoholic fatty liver disease. J. Lipid Res. 2009, 50, 412-416.
    • (2009) Lipid Res , vol.50 , pp. 412-416
    • Erickson, S.K.1
  • 29
    • 4043077961 scopus 로고    scopus 로고
    • Molecular mediators of hepatic steatosis and liver injury. J. Clin
    • Browning, J.D.; Horton, J.D. Molecular mediators of hepatic steatosis and liver injury. J. Clin. Investig. 2004, 114, 147-152.
    • (2004) Investig , vol.114 , pp. 147-152
    • Browning, J.D.1    Horton, J.D.2
  • 30
    • 0037072732 scopus 로고    scopus 로고
    • Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles
    • Grefhorst, A.; Elzinga, B.M.; Voshol, P.J.; Plösch, T.; Kok, T.; Bloks, V.W.; van der Sluijs, F.H.; Havekes, L.M.; Romijn, J.A.; Verkade, H.J.; et al. Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles. J. Biol. Chem. 2002, 277, 34182-34190.
    • (2002) J. Biol. Chem , vol.277 , pp. 34182-34190
    • Grefhorst, A.1    Elzinga, B.M.2    Voshol, P.J.3    Plösch, T.4    Kok, T.5    Bloks, V.W.6    van der Sluijs, F.H.7    Havekes, L.M.8    Romijn, J.A.9    Verkade, H.J.10
  • 33
    • 38649096259 scopus 로고    scopus 로고
    • Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARγ in promoting steatosis
    • Zhou, J.; Febbraio, M.; Wada, T.; Zhai, Y.; Kuruba, R.; He, J.; Lee, J.H.; Khadem, S.; Ren, S.; Li, S.; et al. Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARγ in promoting steatosis. Gastroenterology 2008, 134, 556-567.
    • (2008) Gastroenterology , vol.134 , pp. 556-567
    • Zhou, J.1    Febbraio, M.2    Wada, T.3    Zhai, Y.4    Kuruba, R.5    He, J.6    Lee, J.H.7    Khadem, S.8    Ren, S.9    Li, S.10
  • 34
    • 0037442523 scopus 로고    scopus 로고
    • Molecular cloning and characterization of CIDE-3, a novel member of the cell-death-inducing DNA-fragmentation-factor (DF45)-like effector family. Biochem
    • Liang, L.; Zhao, M.; Xu, Z.; Yokoyama, K.K.; Li, T. Molecular cloning and characterization of CIDE-3, a novel member of the cell-death-inducing DNA-fragmentation-factor (DF45)-like effector family. Biochem. J. 2003, 370, 195-203.
    • (2003) Biochem. J. , vol.370 , pp. 195-203
    • Liang, L.1    Zhao, M.2    Xu, Z.3    Yokoyama, K.K.4    Li, T.5
  • 36
    • 36348940037 scopus 로고    scopus 로고
    • Fat-specific protein 27, a novel lipid droplet protein that enhances triglyceride storage. J. Biol
    • Puri, V.; Konda, S.; Ranjit, S.; Aouadi, M.; Chawla, A.; Chouinard, M.; Chakladar, A.; Czech, M.P. Fat-specific protein 27, a novel lipid droplet protein that enhances triglyceride storage. J. Biol. Chem. 2007, 282, 34213-34218.
    • (2007) Chem , vol.282 , pp. 34213-34218
    • Puri, V.1    Konda, S.2    Ranjit, S.3    Aouadi, M.4    Chawla, A.5    Chouinard, M.6    Chakladar, A.7    Czech, M.P.8
  • 37
    • 0031895898 scopus 로고    scopus 로고
    • Review article: Glycyrrhizin as a potential treatment for chronic hepatitis C. Aliment
    • Van Rossum, T.G.; Vulto, A.G.; de Man, R.A.; Brouwer, J.T.; Schalm, S.W. Review article: Glycyrrhizin as a potential treatment for chronic hepatitis C. Aliment. Pharmacol. Ther. 1998, 12, 199-205.
    • (1998) Pharmacol. Ther , vol.12 , pp. 199-205
    • Van Rossum, T.G.1    Vulto, A.G.2    de Man, R.A.3    Brouwer, J.T.4    Schalm, S.W.5
  • 38
    • 80052807907 scopus 로고    scopus 로고
    • Synthesis of a new [6]-gingerol analogue and its protective effect with respect to the development of metabolic syndrome in mice fed a high-fat diet
    • Okamoto, M.; Irii, H.; Tahara, Y.; Ishii, H.; Hirao, A.; Udagawa, H.; Hiramoto, M.; Yasuda, K.; Takanishi, A.; Shibata, S.; et al. Synthesis of a new [6]-gingerol analogue and its protective effect with respect to the development of metabolic syndrome in mice fed a high-fat diet. J. Med. Chem. 2011, 54, 6295-6304.
    • (2011) J. Med. Chem , vol.54 , pp. 6295-6304
    • Okamoto, M.1    Irii, H.2    Tahara, Y.3    Ishii, H.4    Hirao, A.5    Udagawa, H.6    Hiramoto, M.7    Yasuda, K.8    Takanishi, A.9    Shibata, S.10


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