Single-nucleotide polymorphism in the hyaluronan and proteoglycan link protein 1 (HAPLN1) gene is associated with spinal osteophyte formation and disc degeneration in Japanese women

European Spine Journal

Volumn 20, Issue 4, 2011, Pages 572-577

  Urano, Tomohiko ^a   Narusawa, Ken'ichiro ^b   Shiraki, Masataka ^c   Sasaki, Noriko ^a   Hosoi, Takayuki ^d   Ouchi, Yasuyoshi ^a   Nakamura, Toshitaka ^b   Inoue, Satoshi ^a,e  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^c RESEARCH INSTITUTE AND PRACTICE FOR INVOLUTIONAL DISEASES   (Japan)

^d NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

^e SAITAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Cartilage; Disc degeneration; Hyaluronan and proteoglycan link protein gene (HAPLN1); Osteoarthritis; Single nucleotide polymorphism (SNP)

Indexed keywords

HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 1; PROTEOGLYCAN; UNCLASSIFIED DRUG;

AGED; ARTICLE; CARTILAGE; CONTROLLED STUDY; DISK SPACE NARROWING; ENDPLATE SCLEROSIS; FEMALE; GENOME; GENOTYPE; HUMAN; INTERVERTEBRAL DISK DEGENERATION; INTERVERTEBRAL DISK DISEASE; INTRON; JAPANESE; MAJOR CLINICAL STUDY; OSTEOPHYTE; PATHOGENESIS; POSTMENOPAUSE; PRIORITY JOURNAL; SCLEROSIS; SCORING SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM; SPINAL OSTEOPHYTE; SPINE RADIOGRAPHY;

AGED; ASIAN CONTINENTAL ANCESTRY GROUP; CARTILAGE; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GENOTYPE; HUMANS; INTERVERTEBRAL DISK DEGENERATION; INTRONS; JAPAN; LUMBAR VERTEBRAE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEOGLYCANS; SPINAL OSTEOPHYTOSIS; THORACIC VERTEBRAE;

EID: 79956225910     PISSN: 09406719     EISSN: 14320932     Source Type: Journal    
DOI: 10.1007/s00586-010-1598-0     Document Type: Article

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