메뉴 건너뛰기




Volumn 4, Issue 1, 2015, Pages

Identification of specific metabolites in culture supernatant of Mycobacterium tuberculosis using metabolomics: Exploration of potential biomarkers

Author keywords

biomarkers; diagnosis; metabolomics; Mycobacterium tuberculosis; specific

Indexed keywords

BIOLOGICAL MARKER; 1-TUBERCULOSINYLADENOSINE; DEXPANTHENOL; LIPID; PANTOTHENIC ACID;

EID: 84927922346     PISSN: None     EISSN: 22221751     Source Type: Journal    
DOI: 10.1038/emi.2015.6     Document Type: Article
Times cited : (55)

References (42)
  • 1
    • 84894198937 scopus 로고    scopus 로고
    • Geneva: WHO Available at accessed 2 December 2014
    • World Health Organization. Global tuberculosis report 2014. Geneva: WHO, 2014. Available at http://www.who.int/tb/publications/global-report/en/ (accessed 2 December 2014).
    • (2014) Global Tuberculosis Report 2014
  • 2
    • 79959694800 scopus 로고    scopus 로고
    • Differences in drug resistance profiles of Mycobacterium tuberculosis isolates causing pulmonary and extrapulmonary tuberculosis in a medical centre in Taiwan, 2000-2010
    • Lai CC, Liu WL, Tan CK et al. Differences in drug resistance profiles of Mycobacterium tuberculosis isolates causing pulmonary and extrapulmonary tuberculosis in a medical centre in Taiwan, 2000-2010. Int J Antimicrob Agents 2011; 38: 125-129.
    • (2011) Int J Antimicrob Agents , vol.38 , pp. 125-129
    • Lai, C.C.1    Liu, W.L.2    Tan, C.K.3
  • 3
    • 84883822677 scopus 로고    scopus 로고
    • Genetic diversity of antigens Rv2945c and Rv0309 in Mycobacterium tuberculosis strains may reflect ongoing immune evasion
    • Jiang Y, Dou X, Zhang W et al. Genetic diversity of antigens Rv2945c and Rv0309 in Mycobacterium tuberculosis strains may reflect ongoing immune evasion. FEMS Microbiol Lett 2013; 347: 77-82.
    • (2013) FEMS Microbiol Lett , vol.347 , pp. 77-82
    • Jiang, Y.1    Dou, X.2    Zhang, W.3
  • 4
    • 78650178724 scopus 로고    scopus 로고
    • Prediction of subcellular location of mycobacterial protein using feature selection techniques
    • Lin H, Ding H, Guo FB, Huang J. Prediction of subcellular location of mycobacterial protein using feature selection techniques. Mol Divers 2010; 14: 667-671.
    • (2010) Mol Divers , vol.14 , pp. 667-671
    • Lin, H.1    Ding, H.2    Guo, F.B.3    Huang, J.4
  • 5
    • 84879600678 scopus 로고    scopus 로고
    • Reactive and infective dermatoses associated with adult-onset immunodeficiency due to anti-interferon-gamma autoantibody: Sweet's syndrome and beyond
    • Chan JF, Trendell-Smith NJ, Chan JC et al. Reactive and infective dermatoses associated with adult-onset immunodeficiency due to anti-interferon-gamma autoantibody: Sweet's syndrome and beyond. Dermatology 2013; 226: 157-166.
    • (2013) Dermatology , vol.226 , pp. 157-166
    • Chan, J.F.1    Trendell-Smith, N.J.2    Chan, J.C.3
  • 6
    • 2542468035 scopus 로고    scopus 로고
    • Nontuberculous mycobacterial infection in hematopoietic stem cell and solid organ transplant recipients
    • Doucette K, Fishman JA. Nontuberculous mycobacterial infection in hematopoietic stem cell and solid organ transplant recipients. Clin Infect Dis 2004; 38: 1428-1439.
    • (2004) Clin Infect Dis , vol.38 , pp. 1428-1439
    • Doucette, K.1    Fishman, J.A.2
  • 7
    • 80355126268 scopus 로고    scopus 로고
    • First report of disseminated Mycobacterium skin infections in two liver transplant recipients and rapid diagnosis by hsp65 gene sequencing
    • Lau SK, Curreem SO, Ngan AH, Yeung CK, Yuen KY, Woo PC. First report of disseminated Mycobacterium skin infections in two liver transplant recipients and rapid diagnosis by hsp65 gene sequencing. J Clin Microbiol 2011; 49: 3733-3738.
    • (2011) J Clin Microbiol , vol.49 , pp. 3733-3738
    • Lau, S.K.1    Curreem, S.O.2    Ngan, A.H.3    Yeung, C.K.4    Yuen, K.Y.5    Woo, P.C.6
  • 8
    • 34250314931 scopus 로고    scopus 로고
    • Diagnosis of smear-negative pulmonary tuberculosis in people with HIV infection or AIDS in resourceconstrained settings: Informing urgent policy changes
    • Getahun H, Harrington M, O9Brien R, Nunn P. Diagnosis of smear-negative pulmonary tuberculosis in people with HIV infection or AIDS in resourceconstrained settings: informing urgent policy changes. Lancet 2007; 369: 2042-2049.
    • (2007) Lancet , vol.369 , pp. 2042-2049
    • Getahun, H.1    Harrington, M.2    O'Brien, R.3    Nunn, P.4
  • 9
    • 34250167238 scopus 로고    scopus 로고
    • New approaches and emerging technologies in the diagnosis of childhood tuberculosis
    • Marais BJ, Pai M. New approaches and emerging technologies in the diagnosis of childhood tuberculosis. Paediatr Respir Rev 2007; 8: 124-133.
    • (2007) Paediatr Respir Rev , vol.8 , pp. 124-133
    • Marais, B.J.1    Pai, M.2
  • 10
    • 1542407192 scopus 로고    scopus 로고
    • Clinical evaluation of the polymerase chain reaction for the rapid diagnosis of tuberculosis
    • Cheng VC, Yam WC, Hung IF et al. Clinical evaluation of the polymerase chain reaction for the rapid diagnosis of tuberculosis. J Clin Pathol 2004; 57: 281-285.
    • (2004) J Clin Pathol , vol.57 , pp. 281-285
    • Cheng, V.C.1    Yam, W.C.2    Hung, I.F.3
  • 11
    • 0029083366 scopus 로고
    • Detection and identification of Mycobacterium tuberculosis directly from sputum sediments by Amplicor PCR
    • Moore DF, Curry JI. Detection and identification of Mycobacterium tuberculosis directly from sputum sediments by Amplicor PCR. J Clin Microbiol 1995; 33: 2686-2691.
    • (1995) J Clin Microbiol , vol.33 , pp. 2686-2691
    • Moore, D.F.1    Curry, J.I.2
  • 12
    • 84857231823 scopus 로고    scopus 로고
    • An overview of tuberculosis treatments and diagnostics. What role could metabolomics play?
    • Olivier I, Loots DT. An overview of tuberculosis treatments and diagnostics. What role could metabolomics play? J Cell Tissue Res 2011; 11: 2655-2671.
    • (2011) J Cell Tissue Res , vol.11 , pp. 2655-2671
    • Olivier, I.1    Loots, D.T.2
  • 13
    • 84857232529 scopus 로고    scopus 로고
    • A metabolomics approach to characterise and identify various Mycobacterium species
    • Olivier I, Loots DT. A metabolomics approach to characterise and identify various Mycobacterium species. J Microbiol Methods 2012; 88: 419-426.
    • (2012) J Microbiol Methods , vol.88 , pp. 419-426
    • Olivier, I.1    Loots, D.T.2
  • 14
    • 84868379186 scopus 로고    scopus 로고
    • Ametabolomics investigation of a hyper- and hypo-virulent phenotype of Beijing lineage M. tuberculosis
    • Meissner-Roloff RJ, Koekemoer G, Warren RM, Loots DT. Ametabolomics investigation of a hyper- and hypo-virulent phenotype of Beijing lineage M. tuberculosis. Metabolomics 2012; 8: 1194-1203.
    • (2012) Metabolomics , vol.8 , pp. 1194-1203
    • Meissner-Roloff, R.J.1    Koekemoer, G.2    Warren, R.M.3    Loots, D.T.4
  • 15
    • 84857231853 scopus 로고    scopus 로고
    • Improved disease characterisation and diagnostics using metabolomics: A review
    • Schoeman JC, Loots DT. Improved disease characterisation and diagnostics using metabolomics: a review. J Cell Tissue Res 2011; 11: 2673-2683.
    • (2011) J Cell Tissue Res , vol.11 , pp. 2673-2683
    • Schoeman, J.C.1    Loots, D.T.2
  • 16
    • 84897131722 scopus 로고    scopus 로고
    • Misidentification of Aspergillus nomius and Aspergillus tamarii as Aspergillus flavus: Characterization by internal transcribed spacer, b-tubulin, and calmodulin gene sequencing, metabolic fingerprinting, and matrix-assisted laser desorption ionization-time of flight mass spectrometry
    • Tam EW, Chen JH, Lau EC et al. Misidentification of Aspergillus nomius and Aspergillus tamarii as Aspergillus flavus : characterization by internal transcribed spacer, b-tubulin, and calmodulin gene sequencing, metabolic fingerprinting, and matrix-assisted laser desorption ionization-time of flight mass spectrometry. J Clin Microbiol 2014; 52: 1153-1160.
    • (2014) J Clin Microbiol , vol.52 , pp. 1153-1160
    • Tam, E.W.1    Chen, J.H.2    Lau, E.C.3
  • 17
    • 84871684345 scopus 로고    scopus 로고
    • Characterization of a Tsukamurella pseudo-outbreak by phenotypic tests, 16S rRNA sequencing, pulsed-field gel electrophoresis, and metabolic footprinting
    • To KK, Fung AM, Teng JL et al. Characterization of a Tsukamurella pseudo-outbreak by phenotypic tests, 16S rRNA sequencing, pulsed-field gel electrophoresis, and metabolic footprinting. J Clin Microbiol 2013; 51: 334-338.
    • (2013) J Clin Microbiol , vol.51 , pp. 334-338
    • To, K.K.1    Fung, A.M.2    Teng, J.L.3
  • 18
    • 84869008412 scopus 로고    scopus 로고
    • First discovery of two polyketide synthase genes for mitorubrinic acid and mitorubrinol yellow pigment biosynthesis and implications in virulence of Penicillium marneffei
    • Woo PC, Lam CW, Tam EW et al. First discovery of two polyketide synthase genes for mitorubrinic acid and mitorubrinol yellow pigment biosynthesis and implications in virulence of Penicillium marneffei. PLoS Negl Trop Dis 2012; 6: e1871.
    • (2012) PLoS Negl Trop Dis , vol.6 , pp. e1871
    • Woo, P.C.1    Lam, C.W.2    Tam, E.W.3
  • 19
    • 54749109964 scopus 로고    scopus 로고
    • Analysis of metabolomic data using support vector machines
    • Mahadevan S, Shah SL, Marrie TJ, Slupsky CM. Analysis of metabolomic data using support vector machines. Anal Chem 2008; 80: 7562-7570.
    • (2008) Anal Chem , vol.80 , pp. 7562-7570
    • Mahadevan, S.1    Shah, S.L.2    Marrie, T.J.3    Slupsky, C.M.4
  • 20
    • 3042788092 scopus 로고    scopus 로고
    • The use of urine proteomic and metabonomic patterns for the diagnosis of interstitial cystitis and bacterial cystitis
    • Van QN, Klose JR, Lucas DA et al. The use of urine proteomic and metabonomic patterns for the diagnosis of interstitial cystitis and bacterial cystitis. Dis Markers 2003-2004; 19: 169-183.
    • (2003) Dis Markers , vol.19 , pp. 169-183
    • Van, Q.N.1    Klose, J.R.2    Lucas, D.A.3
  • 21
    • 80054993007 scopus 로고    scopus 로고
    • Development of an integrated metabolomic profiling approach for infectious diseases research
    • Lv H, Hung CS, Chaturvedi KS, Hooton TM, Henderson JP. Development of an integrated metabolomic profiling approach for infectious diseases research. Analyst 2011; 136: 4752-4763.
    • (2011) Analyst , vol.136 , pp. 4752-4763
    • Lv, H.1    Hung, C.S.2    Chaturvedi, K.S.3    Hooton, T.M.4    Henderson, J.P.5
  • 22
    • 33745122975 scopus 로고    scopus 로고
    • Prospects for clinical application of electronic-nose technology to early detection of Mycobacterium tuberculosis in culture and sputum
    • Fend R, Kolk AH, Bessant C, Buijtels P, Klatser PR, Woodman AC. Prospects for clinical application of electronic-nose technology to early detection of Mycobacterium tuberculosis in culture and sputum. J Clin Microbiol 2006; 44: 2039-2045.
    • (2006) J Clin Microbiol , vol.44 , pp. 2039-2045
    • Fend, R.1    Kolk, A.H.2    Bessant, C.3    Buijtels, P.4    Klatser, P.R.5    Woodman, A.C.6
  • 23
    • 78049411009 scopus 로고    scopus 로고
    • Metabolomics of Mycobacterium tuberculosis reveals compartmentalized co-catabolism of carbon substrates
    • de Carvalho LP, Fischer SM, Marrero J, Nathan C, Ehrt S, Rhee KY. Metabolomics of Mycobacterium tuberculosis reveals compartmentalized co-catabolism of carbon substrates. Chem Biol 2010; 17: 1122-1131.
    • (2010) Chem Biol , vol.17 , pp. 1122-1131
    • De Carvalho, L.P.1    Fischer, S.M.2    Marrero, J.3    Nathan, C.4    Ehrt, S.5    Rhee, K.Y.6
  • 24
    • 79960342442 scopus 로고    scopus 로고
    • Use of urine volatile organic compounds to discriminate tuberculosis patients from healthy subjects
    • Banday KM, Pasikanti KK, Chan EC et al. Use of urine volatile organic compounds to discriminate tuberculosis patients from healthy subjects. Anal Chem 2011; 83: 5526-5534.
    • (2011) Anal Chem , vol.83 , pp. 5526-5534
    • Banday, K.M.1    Pasikanti, K.K.2    Chan, E.C.3
  • 25
    • 84885206980 scopus 로고    scopus 로고
    • Application of 1H NMR spectroscopy-based metabolomics to sera of tuberculosis patients
    • Zhou A, Ni J, Xu Z et al. Application of 1H NMR spectroscopy-based metabolomics to sera of tuberculosis patients. J Proteome Res 2013; 12: 4642-4649.
    • (2013) J Proteome Res , vol.12 , pp. 4642-4649
    • Zhou, A.1    Ni, J.2    Xu, Z.3
  • 26
    • 84867449305 scopus 로고    scopus 로고
    • Metabolomic signatures in guinea pigs infected with epidemic-associated W-Beijing strains of Mycobacterium tuberculosis
    • Somashekar BS, Amin AG, Tripathi P et al. Metabolomic signatures in guinea pigs infected with epidemic-associated W-Beijing strains of Mycobacterium tuberculosis. J Proteome Res 2012; 11: 4873-4884.
    • (2012) J Proteome Res , vol.11 , pp. 4873-4884
    • Somashekar, B.S.1    Amin, A.G.2    Tripathi, P.3
  • 27
    • 59049106348 scopus 로고    scopus 로고
    • Analysis of fatty acids in sputum from patients with pulmonary tuberculosis using gas chromatography-mass spectrometry preceded by solid-phase microextraction and post-derivatization on the fiber
    • Cha D, Cheng D, Liu M, Zeng Z, Hu X, Guan W. Analysis of fatty acids in sputum from patients with pulmonary tuberculosis using gas chromatography-mass spectrometry preceded by solid-phase microextraction and post-derivatization on the fiber. J Chromatogr A 2009; 1216: 1450-1457.
    • (2009) J Chromatogr A , vol.1216 , pp. 1450-1457
    • Cha, D.1    Cheng, D.2    Liu, M.3    Zeng, Z.4    Hu, X.5    Guan, W.6
  • 29
    • 0347511902 scopus 로고    scopus 로고
    • Individual Mycobacterium tuberculosis resuscitation-promoting factor homologues are dispensable for growth in vitro and in vivo
    • Tufariello JM, Jacobs WR Jr, Chan J. Individual Mycobacterium tuberculosis resuscitation-promoting factor homologues are dispensable for growth in vitro and in vivo. Infect Immun 2004; 72: 515-526.
    • (2004) Infect Immun , vol.72 , pp. 515-526
    • Tufariello, J.M.1    Jacobs, W.R.2    Chan, J.3
  • 30
    • 32444446805 scopus 로고    scopus 로고
    • XCMS: Processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification
    • Smith CA, Want EJ, O9Maille G, Abagyan R, Siuzdak G. XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification. Anal Chem 2006; 78: 779-787.
    • (2006) Anal Chem , vol.78 , pp. 779-787
    • Smith, C.A.1    Want, E.J.2    O'Maille, G.3    Abagyan, R.4    Siuzdak, G.5
  • 31
    • 60649089559 scopus 로고    scopus 로고
    • Highly sensitive feature detection for high resolution LC/MS
    • Tautenhahn R, Böttcher C, Neumann S. Highly sensitive feature detection for high resolution LC/MS. BMC Bioinformatics 2008; 9: 504.
    • (2008) BMC Bioinformatics , vol.9 , pp. 504
    • Tautenhahn, R.1    Böttcher, C.2    Neumann, S.3
  • 33
    • 84855402302 scopus 로고    scopus 로고
    • CAMERA: An integrated strategy for compound spectra extraction and annotation of liquid chromatography/mass spectrometry data sets
    • Kuhl C, Tautenhahn R, Böttcher C, Larson TR, Neumann S. CAMERA: an integrated strategy for compound spectra extraction and annotation of liquid chromatography/mass spectrometry data sets. Anal Chem 2012; 84: 283-289.
    • (2012) Anal Chem , vol.84 , pp. 283-289
    • Kuhl, C.1    Tautenhahn, R.2    Böttcher, C.3    Larson, T.R.4    Neumann, S.5
  • 34
    • 84896847440 scopus 로고    scopus 로고
    • Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c
    • Layre E, Lee HJ, Young DC et al. Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c. Proc Natl Acad Sci USA 2014; 111: 2978-2983.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 2978-2983
    • Layre, E.1    Lee, H.J.2    Young, D.C.3
  • 35
    • 79954999132 scopus 로고    scopus 로고
    • Lipidomic analyses of Mycobacterium tuberculosis based on accurate mass measurements and the novel "Mtb LipidDB"
    • Sartain MJ, Dick DL, Rithner CD, Crick DC, Belisle JT. Lipidomic analyses of Mycobacterium tuberculosis based on accurate mass measurements and the novel "Mtb LipidDB". J Lipid Res 2011; 52: 861-872.
    • (2011) J Lipid Res , vol.52 , pp. 861-872
    • Sartain, M.J.1    Dick, D.L.2    Rithner, C.D.3    Crick, D.C.4    Belisle, J.T.5
  • 36
    • 51449112852 scopus 로고    scopus 로고
    • Cardiolipin synthesis for the assembly of bacterial and mitochondrial membranes
    • Schlame M. Cardiolipin synthesis for the assembly of bacterial and mitochondrial membranes. J Lipid Res 2008; 49: 1607-1620.
    • (2008) J Lipid Res , vol.49 , pp. 1607-1620
    • Schlame, M.1
  • 37
    • 0036796061 scopus 로고    scopus 로고
    • A pantothenate auxotroph of Mycobacterium tuberculosis is highly attenuated and protects mice against tuberculosis
    • Sambandamurthy VK, Wang X, Chen B et al. A pantothenate auxotroph of Mycobacterium tuberculosis is highly attenuated and protects mice against tuberculosis. Nat Med 2002; 8: 1171-1174.
    • (2002) Nat Med , vol.8 , pp. 1171-1174
    • Sambandamurthy, V.K.1    Wang, X.2    Chen, B.3
  • 38
    • 34547856677 scopus 로고    scopus 로고
    • How pantothenol intervenes in Coenzyme-A biosynthesis of Mycobacterium tuberculosis
    • Kumar P, Chhibber M, Surolia A. How pantothenol intervenes in Coenzyme-A biosynthesis of Mycobacterium tuberculosis. Biochem Biophys Res Commun 2007; 361: 903-909.
    • (2007) Biochem Biophys Res Commun , vol.361 , pp. 903-909
    • Kumar, P.1    Chhibber, M.2    Surolia, A.3
  • 39
    • 11144336256 scopus 로고
    • Growth inhibition by analogues of pantothenic acid. Pantothenyl alcohol and related compounds
    • Snell EE, Shive W. Growth inhibition by analogues of pantothenic acid. Pantothenyl alcohol and related compounds. J Biol Chem 1945; 158: 551-559.
    • (1945) J Biol Chem , vol.158 , pp. 551-559
    • Snell, E.E.1    Shive, W.2
  • 40
    • 27644471425 scopus 로고    scopus 로고
    • A class of pantothenic acid analogs inhibits Plasmodium falciparum pantothenate kinase and represses the proliferation of malaria parasites
    • Spry C, Chai CL, Kirk K, Saliba KJ. A class of pantothenic acid analogs inhibits Plasmodium falciparum pantothenate kinase and represses the proliferation of malaria parasites. Antimicrob Agents Chemother 2005; 49 : 4649-4657.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 4649-4657
    • Spry, C.1    Chai, C.L.2    Kirk, K.3    Saliba, K.J.4
  • 41
    • 4544346542 scopus 로고    scopus 로고
    • Isolation of Mycobacterium tuberculosis mutants defective in the arrest of phagosome maturation
    • Pethe K, Swenson DL, Alonso S, Anderson J, Wang C, Russell DG. Isolation of Mycobacterium tuberculosis mutants defective in the arrest of phagosome maturation. Proc Natl Acad Sci USA 2004; 101: 13642-13647.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 13642-13647
    • Pethe, K.1    Swenson, D.L.2    Alonso, S.3    Anderson, J.4    Wang, C.5    Russell, D.G.6
  • 42
    • 80053456051 scopus 로고    scopus 로고
    • Serum metabolomics reveals higher levels of polyunsaturated fatty acids in lepromatous leprosy: Potential markers for susceptibility and pathogenesis
    • Al-Mubarak R, Vander Heiden J, Broeckling CD, Balagon M, Brennan PJ, Vissa VD. Serum metabolomics reveals higher levels of polyunsaturated fatty acids in lepromatous leprosy: potential markers for susceptibility and pathogenesis. PLoS Negl Trop Dis 2011; 5: e1303.
    • (2011) PLoS Negl Trop Dis , vol.5 , pp. e1303
    • Al-Mubarak, R.1    Vander Heiden, J.2    Broeckling, C.D.3    Balagon, M.4    Brennan, P.J.5    Vissa, V.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.