An activated unfolded protein response promotes retinal degeneration and triggers an inflammatory response in the mouse retina

Cell Death and Disease

Volumn 5, Issue 12, 2014, Pages

  Rana, T ^a   Shinde, V M ^a   Starr, C R ^a   Kruglov, A A ^a   Boitet, E R ^a   Kotla, P ^a   Zolotukhin, S ^b   Gross, A K ^a   Gorbatyuk, M S ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EYE PROTEIN; IBA1 PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; RECOMBINANT INTERLEUKIN 1BETA; RHODOPSIN; RNA; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; TUNICAMYCIN; UNCLASSIFIED DRUG; TUMOR NECROSIS FACTOR;

A WAVE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DISEASE ASSOCIATION; DISEASE COURSE; ELECTRORETINOGRAPHY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; INFLAMMATION; MICROGLIA; MOLECULAR PATHOLOGY; MOUSE; MUTANT; NONHUMAN; PHOTORECEPTOR CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RETINA; RETINA DEGENERATION; RETINITIS; RNA ANALYSIS; SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY; UNFOLDED PROTEIN RESPONSE; UPREGULATION; ANIMAL; C57BL MOUSE; DISEASE MODEL; GENETICS; IMMUNOLOGY; METABOLISM;

ANIMALIA; MUS;

ANIMALS; CHEMOKINE CCL2; DISEASE MODELS, ANIMAL; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-6; MICE; MICE, INBRED C57BL; PHOTORECEPTOR CELLS, VERTEBRATE; RETINA; RETINAL DEGENERATION; TUMOR NECROSIS FACTOR-ALPHA; UNFOLDED PROTEIN RESPONSE;

EID: 84927918617     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.539     Document Type: Article

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