Functional rescue of P23H rhodopsin photoreceptors by gene delivery

Advances in Experimental Medicine and Biology

Volumn 723, Issue , 2012, Pages 191-197

  Gorbatyuk, Marina S ^a   Gorbatyuk, Oleg S ^b   LaVail, Matthew M ^c   Lin, Jonathan H ^d   Hauswirth, William W ^e   Lewin, Alfred S ^b  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

BiP Grp78; ER Stress; ERG; Folding; Gene Delivery; Gene Therapy; P23H Rhodopsin; siRNA; Transgenic Rats

Indexed keywords

GLUCOSE REGULATED PROTEIN 78; HEAT SHOCK TRANSCRIPTION FACTOR 1; PARVOVIRUS VECTOR; RHODOPSIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; CELL SURVIVAL; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFECT; ELECTRORETINOGRAPHY; GENE MUTATION; GENE OVEREXPRESSION; IN VITRO STUDY; NONHUMAN; PHOTORECEPTOR; PHOTORECEPTOR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UNFOLDED PROTEIN RESPONSE; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; WILD TYPE;

ANIMALS; DEPENDOVIRUS; DNA-BINDING PROTEINS; ELECTRORETINOGRAPHY; ENDOPLASMIC RETICULUM STRESS; GENE THERAPY; GENE TRANSFER TECHNIQUES; HEAT-SHOCK PROTEINS; HELA CELLS; HUMANS; PHOTORECEPTOR CELLS, VERTEBRATE; PROTEIN TRANSPORT; PROTEOSTASIS DEFICIENCIES; RATS; RATS, TRANSGENIC; RETINITIS PIGMENTOSA; RHODOPSIN; RNA, SMALL INTERFERING; TRANSCRIPTION FACTORS;

RATTUS;

EID: 84862964473     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4614-0631-0_26     Document Type: Conference Paper

References (7)

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