-
1
-
-
84856749765
-
Certolizumab pegol compared to natalizumab in patients with moderate to severe Crohn's disease: results of a decision analysis
-
Ananthakrishnan A. Hur C. Korzenik R. (2012) Certolizumab pegol compared to natalizumab in patients with moderate to severe Crohn's disease: results of a decision analysis. Dig Dis Sci 57: 472–480.
-
(2012)
Dig Dis Sci
, vol.57
, pp. 472-480
-
-
Ananthakrishnan, A.1
Hur, C.2
Korzenik, R.3
-
4
-
-
0035122721
-
The history of Crohn's disease
-
Aufses A. Jr. (2001) The history of Crohn's disease. Surg Clin N Am 81: 1–11.
-
(2001)
Surg Clin N Am
, vol.81
, pp. 1-11
-
-
Aufses, A.1
-
5
-
-
84890096310
-
Crohn's disease: a review of treatment options and current research
-
Bandzar S. Gupta S. Platt M. (2013) Crohn's disease: a review of treatment options and current research. Cell Immunol 286: 45–52.
-
(2013)
Cell Immunol
, vol.286
, pp. 45-52
-
-
Bandzar, S.1
Gupta, S.2
Platt, M.3
-
6
-
-
84868212109
-
Crohn's disease
-
Baumgart D. Sandborn W. (2012) Crohn's disease. Lancet 380: 1590–1605.
-
(2012)
Lancet
, vol.380
, pp. 1590-1605
-
-
Baumgart, D.1
Sandborn, W.2
-
7
-
-
46149117709
-
PROTECT-1, prospective randomized oral therapy evaluation of CCX282-B (TRAFICET-EN) in Crohn's disease
-
Bekker P. Schreiber S. Keshav S. (2007) PROTECT-1, prospective randomized oral therapy evaluation of CCX282-B (TRAFICET-EN) in Crohn's disease. Gut 56: A23.
-
(2007)
Gut
, vol.56
, pp. A23
-
-
Bekker, P.1
Schreiber, S.2
Keshav, S.3
-
9
-
-
0022411888
-
Passive immunization against cachectin / tumor necrosis factor protects mice from lethal effect of endotoxin
-
Beutler B. Milsark I. Cerami A. (1985) Passive immunization against cachectin / tumor necrosis factor protects mice from lethal effect of endotoxin. Science 229: 869–871.
-
(1985)
Science
, vol.229
, pp. 869-871
-
-
Beutler, B.1
Milsark, I.2
Cerami, A.3
-
10
-
-
79953786419
-
Loss of response and need for adalimumab dose intensification in Crohn's disease: a systematic review
-
Billioud V. Sandborn W. Peyrin-Biroulet L. (2011) Loss of response and need for adalimumab dose intensification in Crohn's disease: a systematic review. Am J Gastroenterol 106: 674–684.
-
(2011)
Am J Gastroenterol
, vol.106
, pp. 674-684
-
-
Billioud, V.1
Sandborn, W.2
Peyrin-Biroulet, L.3
-
12
-
-
0030041584
-
Long-term follow-up of patients with Crohn's disease treated with azathioprine or 6-mercaptopurine
-
Bouhnik Y. Scemama G. Taï R. Matuchansky C. Rambaud J. Lémann M. et al. (1996) Long-term follow-up of patients with Crohn's disease treated with azathioprine or 6-mercaptopurine. Lancet 347: 215–219.
-
(1996)
Lancet
, vol.347
, pp. 215-219
-
-
Bouhnik, Y.1
Scemama, G.2
Taï, R.3
Matuchansky, C.4
Rambaud, J.5
Lémann, M.6
-
14
-
-
33745553245
-
A phase 1/2A trial of STA 5326, an oral interleukin-12/23 inhibitor, in patients with active moderate to severe Crohn's disease
-
Burakoff R. Barish C. Riff D. Pruitt R. Chey W. Farraye F. et al. (2006) A phase 1/2A trial of STA 5326, an oral interleukin-12/23 inhibitor, in patients with active moderate to severe Crohn's disease. Inflamm Bowel Dis 12: 558–565.
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 558-565
-
-
Burakoff, R.1
Barish, C.2
Riff, D.3
Pruitt, R.4
Chey, W.5
Farraye, F.6
-
16
-
-
84874445437
-
Adalimumab: Long-term safety in 23 458 patients from global clinical trials in rheumatoid arthritis, juvenile idiopathic arthritis, ankylosing spondylitis, psoriatic arthritis, psoriasis and Crohn's disease
-
Burmester G. Panaccione R. Gordon K. McIlraith M. Lacerda A. (2013) Adalimumab: Long-term safety in 23 458 patients from global clinical trials in rheumatoid arthritis, juvenile idiopathic arthritis, ankylosing spondylitis, psoriatic arthritis, psoriasis and Crohn's disease. Ann Rheum Dis 72: 517–524.
-
(2013)
Ann Rheum Dis
, vol.72
, pp. 517-524
-
-
Burmester, G.1
Panaccione, R.2
Gordon, K.3
McIlraith, M.4
Lacerda, A.5
-
17
-
-
77958150896
-
Case report: fatal case of disseminated BCG infection in an infant born to a mother taking infliximab for Crohn's disease
-
Cheent K. Nolan J. Shariq S. Kiho L. Pal A. Arnold J. (2010). Case report: fatal case of disseminated BCG infection in an infant born to a mother taking infliximab for Crohn's disease. J Crohns Colitis 4: 603–605.
-
(2010)
J Crohns Colitis
, vol.4
, pp. 603-605
-
-
Cheent, K.1
Nolan, J.2
Shariq, S.3
Kiho, L.4
Pal, A.5
Arnold, J.6
-
18
-
-
22944444890
-
Monoclonal antibodies, immunogenicity and associated infusion reactions
-
Cheifetz A. Mayer L. (2005) Monoclonal antibodies, immunogenicity and associated infusion reactions. Mt Sin J Med 72: 250-256.
-
(2005)
Mt Sin J Med
, vol.72
, pp. 250-256
-
-
Cheifetz, A.1
Mayer, L.2
-
19
-
-
0038649858
-
The incidence and management of infusion reactions to infliximab: a large center experience
-
Cheifetz A. Smedley M. Martin S. Reiter M. Leone G. Mayer L. et al. (2003) The incidence and management of infusion reactions to infliximab: a large center experience. Am J Gastroenterol 98: 1315–1324.
-
(2003)
Am J Gastroenterol
, vol.98
, pp. 1315-1324
-
-
Cheifetz, A.1
Smedley, M.2
Martin, S.3
Reiter, M.4
Leone, G.5
Mayer, L.6
-
20
-
-
84893898345
-
Association between plasma concentrations of certolizumab pegol and endoscopic outcomes of patients with Crohn's disease
-
Colombel J. Sandborn W. Allez M. Dupas J. Dewit O. D'Haens G. et al. (2014) Association between plasma concentrations of certolizumab pegol and endoscopic outcomes of patients with Crohn's disease. Clin Gastroenterol Hepatol 12: 423–431.
-
(2014)
Clin Gastroenterol Hepatol
, vol.12
, pp. 423-431
-
-
Colombel, J.1
Sandborn, W.2
Allez, M.3
Dupas, J.4
Dewit, O.5
D'Haens, G.6
-
21
-
-
77950988234
-
Infliximab, azathioprine, or combination therapy for Crohn's disease
-
Colombel J. Sandborn W. Reinisch W. Mantzaris G. Kornbluth A. Rachmilewitz D. et al. (2010) Infliximab, azathioprine, or combination therapy for Crohn's disease. N Eng J Med 362: 1383–1395.
-
(2010)
N Eng J Med
, vol.362
, pp. 1383-1395
-
-
Colombel, J.1
Sandborn, W.2
Reinisch, W.3
Mantzaris, G.4
Kornbluth, A.5
Rachmilewitz, D.6
-
22
-
-
33846242958
-
Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: The CHARM trial
-
Colombel J. Sandborn W. Rutgeerts P. Enns R. Hanauer S. Panaccione R. et al. (2007) Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: The CHARM trial. Gastroenterology 132: 52–65.
-
(2007)
Gastroenterology
, vol.132
, pp. 52-65
-
-
Colombel, J.1
Sandborn, W.2
Rutgeerts, P.3
Enns, R.4
Hanauer, S.5
Panaccione, R.6
-
24
-
-
84930302282
-
Regional ileitis: a pathologic and clinical entity
-
Crohn B. Ginzburg L. Oppenheimer G. (1932) Regional ileitis: a pathologic and clinical entity. JAMA 99: 1323–1329.
-
(1932)
JAMA
, vol.99
, pp. 1323-1329
-
-
Crohn, B.1
Ginzburg, L.2
Oppenheimer, G.3
-
25
-
-
0032913394
-
Endoscopic and histological healing with infliximab anti–tumor necrosis factor antibodies in Crohn's disease: a European multicenter trial
-
D'Haens G. van Deventer S. van Hogezand R. Chalmers D. Kothe C. Baert F. et al. (1999) Endoscopic and histological healing with infliximab anti–tumor necrosis factor antibodies in Crohn's disease: a European multicenter trial. Gastroenterology 116: 1029–1034.
-
(1999)
Gastroenterology
, vol.116
, pp. 1029-1034
-
-
D'Haens, G.1
van Deventer, S.2
van Hogezand, R.3
Chalmers, D.4
Kothe, C.5
Baert, F.6
-
26
-
-
84879229639
-
Efficacy and safety of certolizumab pegol for Crohn's disease: a systematic review and meta-analysis
-
Da W. Zhu J. Wang L. Lu Y. (2013) Efficacy and safety of certolizumab pegol for Crohn's disease: a systematic review and meta-analysis. Adv Ther 30: 541–553.
-
(2013)
Adv Ther
, vol.30
, pp. 541-553
-
-
Da, W.1
Zhu, J.2
Wang, L.3
Lu, Y.4
-
27
-
-
0032920388
-
Relationship of extraintestinal involvements in inflammatory bowel disease (new insights into autoimmune pathogenesis)
-
Das K. (1999) Relationship of extraintestinal involvements in inflammatory bowel disease (new insights into autoimmune pathogenesis). Dig Dis Sci 44: 1–13.
-
(1999)
Dig Dis Sci
, vol.44
, pp. 1-13
-
-
Das, K.1
-
28
-
-
0027438710
-
Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha
-
Elliott M. Maini R. Feldmann M. Long-Fox A. Charles P. Katsikis P. et al. (1993) Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha. Arthritis Rheum 36: 1681–1690.
-
(1993)
Arthritis Rheum
, vol.36
, pp. 1681-1690
-
-
Elliott, M.1
Maini, R.2
Feldmann, M.3
Long-Fox, A.4
Charles, P.5
Katsikis, P.6
-
29
-
-
57249089077
-
Treatment of active Crohn's disease with MLN0002, a humanized antibody to the α4β7 integrin
-
Feagan B. Greenberg G. Wild G. Fedorak R. Paré P. McDonald J. et al. (2008) Treatment of active Crohn's disease with MLN0002, a humanized antibody to the α4β7 integrin. Clin Gastroenterol Hepatol 6: 1370–1377.
-
(2008)
Clin Gastroenterol Hepatol
, vol.6
, pp. 1370-1377
-
-
Feagan, B.1
Greenberg, G.2
Wild, G.3
Fedorak, R.4
Paré, P.5
McDonald, J.6
-
30
-
-
20044382590
-
A randomized, double-blind, placebo-controlled trial of CDP571, a humanized monoclonal antibody to tumour necrosis factor-α, in patients with corticosteroid-dependent Crohn's disease
-
Feagan B. Sandborn W. Baker J. Cominelli F. Sutherland L. Elson C. et al. (2005) A randomized, double-blind, placebo-controlled trial of CDP571, a humanized monoclonal antibody to tumour necrosis factor-α, in patients with corticosteroid-dependent Crohn's disease. Alim Pharm Ther 21: 373–384.
-
(2005)
Alim Pharm Ther
, vol.21
, pp. 373-384
-
-
Feagan, B.1
Sandborn, W.2
Baker, J.3
Cominelli, F.4
Sutherland, L.5
Elson, C.6
-
31
-
-
0035056003
-
Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned?
-
Feldman M. Maini R. (2001) Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned? Ann Rev Immunol 19: 163–169.
-
(2001)
Ann Rev Immunol
, vol.19
, pp. 163-169
-
-
Feldman, M.1
Maini, R.2
-
32
-
-
79953801792
-
Efficacy of biological therapies in inflammatory bowel disease: systematic review and meta-analysis
-
Ford A. Sandborn W. Khan K. Hanauer S. Talley N. Moayyedi P. (2011) Efficacy of biological therapies in inflammatory bowel disease: systematic review and meta-analysis. Am J Gastroenterol 106: 644–659.
-
(2011)
Am J Gastroenterol
, vol.106
, pp. 644-659
-
-
Ford, A.1
Sandborn, W.2
Khan, K.3
Hanauer, S.4
Talley, N.5
Moayyedi, P.6
-
33
-
-
84993715808
-
Changing Incidence of inflammatory bowel disease: environmental influences and lessons learnt from the South Asia population
-
Foster A. Jacobson K. (2013) Changing Incidence of inflammatory bowel disease: environmental influences and lessons learnt from the South Asia population. Front Pediatr 1: 1–7.
-
(2013)
Front Pediatr
, vol.1
, pp. 1-7
-
-
Foster, A.1
Jacobson, K.2
-
34
-
-
84903581140
-
Inflammatory bowel disease
-
18th edn New York, NY: Mc-Graw Hill
-
Friedman S. Blumberg R.S. (2012) Inflammatory bowel disease. In: Ed. Longo D.L. Fauci A.S. Kasper D.L. Hauser S.L. Jameson J. Loscalzo J. (eds), Harrison's Principles of Internal Medicine, 18th edn. New York, NY: Mc-Graw Hill, pp. 2477–2495.
-
(2012)
Harrison's Principles of Internal Medicine
, pp. 2477-2495
-
-
Friedman, S.1
Blumberg, R.S.2
Longo, D.L.3
Fauci, A.S.4
Kasper, D.L.5
Hauser, S.L.6
Jameson, J.7
Loscalzo, J.8
-
35
-
-
84993726713
-
perinatal pathologic examination of non-intact, second trimester fetal demise specimens: the value of standardization
-
Gawron L. Hammond C. Ernst L. (2013) perinatal pathologic examination of non-intact, second trimester fetal demise specimens: the value of standardization. Arch Pathol Lab Med 167: 326–331.
-
(2013)
Arch Pathol Lab Med
, vol.167
, pp. 326-331
-
-
Gawron, L.1
Hammond, C.2
Ernst, L.3
-
37
-
-
0034903450
-
A randomized placebo-controlled trial of a humanized monoclonal antibody to α4 integrin in active Crohn's disease
-
Gordon F. Lai C. Hamilton M. Allison M. Srivastava E. Fouweather M. et al. (2001) A randomized placebo-controlled trial of a humanized monoclonal antibody to α4 integrin in active Crohn's disease. Gastroenterology 121: 268–274.
-
(2001)
Gastroenterology
, vol.121
, pp. 268-274
-
-
Gordon, F.1
Lai, C.2
Hamilton, M.3
Allison, M.4
Srivastava, E.5
Fouweather, M.6
-
38
-
-
0023137851
-
Spontaneous free perforation and perforated abscess in 30 patients with Crohn's disease
-
Greenstein A. Sachar D. Mann D. Lachman P. Heimann T. Aufses A. Jr (1987) Spontaneous free perforation and perforated abscess in 30 patients with Crohn's disease. Ann Surg 205: 72–76.
-
(1987)
Ann Surg
, vol.205
, pp. 72-76
-
-
Greenstein, A.1
Sachar, D.2
Mann, D.3
Lachman, P.4
Heimann, T.5
Aufses, A.6
-
40
-
-
32044451548
-
Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC trial
-
Hanauer S. Sandborn W. Rutgeerts P. Fedorak R. Lukas M. MacIntosh D. et al. (2006) Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC trial. Gastroenterology 130: 323–33.
-
(2006)
Gastroenterology
, vol.130
, pp. 323-333
-
-
Hanauer, S.1
Sandborn, W.2
Rutgeerts, P.3
Fedorak, R.4
Lukas, M.5
MacIntosh, D.6
-
41
-
-
0006094474
-
Chronic cicatrizing enteritis: regional ileitis (Crohn). A new surgical entity
-
Harris F. Bell G. Brunn H. (1933) Chronic cicatrizing enteritis: regional ileitis (Crohn). A new surgical entity. Surg Gynecol Obstet 57: 637–645.
-
(1933)
Surg Gynecol Obstet
, vol.57
, pp. 637-645
-
-
Harris, F.1
Bell, G.2
Brunn, H.3
-
42
-
-
79953066058
-
Crohn's disease. M
-
Hart A. Ng S. (2011) Crohn's disease. M edicine 39: 229–236.
-
(2011)
edicine
, vol.39
, pp. 229-236
-
-
Hart, A.1
Ng, S.2
-
43
-
-
0035978651
-
Association of NOD 2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
Hugot J. Chamaillard M. Zouali H. Lesage S. Cézard J. Belaiche J. et al. (2001) Association of NOD 2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 411: 599–603.
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.1
Chamaillard, M.2
Zouali, H.3
Lesage, S.4
Cézard, J.5
Belaiche, J.6
-
44
-
-
11144358366
-
A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn's disease
-
Ito H. Takazoe M. Fukuda Y. Hibi T. Kusugami K. Andoh A. et al. (2004) A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn's disease. Gastroenterology 126: 989–996.
-
(2004)
Gastroenterology
, vol.126
, pp. 989-996
-
-
Ito, H.1
Takazoe, M.2
Fukuda, Y.3
Hibi, T.4
Kusugami, K.5
Andoh, A.6
-
45
-
-
84888271656
-
Efficacy and safety of natalizumab in Crohn's disease patients treated at 6 Boston academic hospitals
-
Juillerat P. Wasan S. Fowler S. Friedman S. Pabby V. Coukas J. et al. (2013) Efficacy and safety of natalizumab in Crohn's disease patients treated at 6 Boston academic hospitals. Inflamm Bowel Dis 19: 2457–2463.
-
(2013)
Inflamm Bowel Dis
, vol.19
, pp. 2457-2463
-
-
Juillerat, P.1
Wasan, S.2
Fowler, S.3
Friedman, S.4
Pabby, V.5
Coukas, J.6
-
46
-
-
84869215386
-
Natalizumab for moderate to severe Crohn's disease in clinical practice: the Mayo Clinic Rochester experience
-
Kane S. Horst S. Sandborn W. Becker B. Neis B. Moscandrew M. et al. (2012) Natalizumab for moderate to severe Crohn's disease in clinical practice: the Mayo Clinic Rochester experience. Inflamm Bowel Dis 18: 2203–2208.
-
(2012)
Inflamm Bowel Dis
, vol.18
, pp. 2203-2208
-
-
Kane, S.1
Horst, S.2
Sandborn, W.3
Becker, B.4
Neis, B.5
Moscandrew, M.6
-
47
-
-
0026039673
-
Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis
-
Keffer J. Probert L. Cazlaris H. Georgopoulos S. Kaslaris E. Kioussis D. et al. (1991) Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis. EMBO J 10: 4025–4031.
-
(1991)
EMBO J
, vol.10
, pp. 4025-4031
-
-
Keffer, J.1
Probert, L.2
Cazlaris, H.3
Georgopoulos, S.4
Kaslaris, E.5
Kioussis, D.6
-
48
-
-
77957227230
-
PROTECT-1 study demonstrated efficacy of the intestine-specific chemokine receptor antagonist CCX282-B (Traficet-EN) in treatment of patients with moderate to severe Crohn's disease
-
Keshav S. Johnson D. Bekker P. Schall T. (2009) PROTECT-1 study demonstrated efficacy of the intestine-specific chemokine receptor antagonist CCX282-B (Traficet-EN) in treatment of patients with moderate to severe Crohn's disease. Gastroenterology 136: A65.
-
(2009)
Gastroenterology
, vol.136
, pp. A65
-
-
Keshav, S.1
Johnson, D.2
Bekker, P.3
Schall, T.4
-
49
-
-
84875195096
-
A randomized controlled trial of the efficacy and safety of CCX282-B, an orally-administered blocker of chemokine receptor CCR9, for patients with Crohn's disease
-
Keshav S. Vaňásek T. Niv Y. Petryka R. Howaldt S. Bafutto M. et al. (2013) A randomized controlled trial of the efficacy and safety of CCX282-B, an orally-administered blocker of chemokine receptor CCR9, for patients with Crohn's disease. PLoS On, 8: e60094.
-
(2013)
PLoS On
, vol.8
, pp. e60094
-
-
Keshav, S.1
Vaňásek, T.2
Niv, Y.3
Petryka, R.4
Howaldt, S.5
Bafutto, M.6
-
50
-
-
0023770957
-
Historical aspects of inflammatory bowel disease
-
Kirsner J. (1988) Historical aspects of inflammatory bowel disease. J Clin Gastroenterol 10: 286–297.
-
(1988)
J Clin Gastroenterol
, vol.10
, pp. 286-297
-
-
Kirsner, J.1
-
51
-
-
22844439662
-
Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis
-
Kleinschmidt-deMasters B. Tyler K. (2005) Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis. N Engl J Med 353: 369–374.
-
(2005)
N Engl J Med
, vol.353
, pp. 369-374
-
-
Kleinschmidt-deMasters, B.1
Tyler, K.2
-
52
-
-
59749093368
-
Practice Parameters Committee of American College of Gastroenterology; management of Crohn's disease in adults
-
Lichtenstein G. Hanauer S. Sandborn W. (2009) Practice Parameters Committee of American College of Gastroenterology; management of Crohn's disease in adults. Am J Gastroenterol 104: 465–483.
-
(2009)
Am J Gastroenterol
, vol.104
, pp. 465-483
-
-
Lichtenstein, G.1
Hanauer, S.2
Sandborn, W.3
-
53
-
-
33646581382
-
Factors associated with the development of intestinal strictures or obstructions in patients with Crohn's disease
-
Lichtenstein G. Olson A. Travers S. Diamond R. Chen D. Pritchard M. et al. (2006) Factors associated with the development of intestinal strictures or obstructions in patients with Crohn's disease. Am J Gastroenterol 101: 1030–1038.
-
(2006)
Am J Gastroenterol
, vol.101
, pp. 1030-1038
-
-
Lichtenstein, G.1
Olson, A.2
Travers, S.3
Diamond, R.4
Chen, D.5
Pritchard, M.6
-
55
-
-
84863724798
-
A pooled analysis of infections, malignancy and mortality in infliximab-and immunomodulator-treated adult patients with inflammatory bowel disease
-
Lichtenstein G. Rutgeerts P. Sandborn W. Sands B. Diamond R. Blank M. et al. (2012) A pooled analysis of infections, malignancy and mortality in infliximab-and immunomodulator-treated adult patients with inflammatory bowel disease. Am J Gastroenterol 107: 1051–1063.
-
(2012)
Am J Gastroenterol
, vol.107
, pp. 1051-1063
-
-
Lichtenstein, G.1
Rutgeerts, P.2
Sandborn, W.3
Sands, B.4
Diamond, R.5
Blank, M.6
-
57
-
-
17144388945
-
Infliximab maintenance treatment reduces hospitalizations, surgeries and procedures in fistulizing Crohn's disease
-
Lichtenstein G. Yan S. Bala M. Blank M. Sands B. (2005) Infliximab maintenance treatment reduces hospitalizations, surgeries and procedures in fistulizing Crohn's disease. Gastroenterology 128: 862–869.
-
(2005)
Gastroenterology
, vol.128
, pp. 862-869
-
-
Lichtenstein, G.1
Yan, S.2
Bala, M.3
Blank, M.4
Sands, B.5
-
58
-
-
0000960795
-
Crohn's disease (regional enteritis) of the large intestine and its distinction from ulcerative colitis
-
Lockhart-Mummery H. Morson B. (1960) Crohn's disease (regional enteritis) of the large intestine and its distinction from ulcerative colitis. Gut 1: 87–105.
-
(1960)
Gut
, vol.1
, pp. 87-105
-
-
Lockhart-Mummery, H.1
Morson, B.2
-
59
-
-
0036161786
-
The epidemiology and natural history of Crohn's disease in population-based patient cohorts from North America: a systematic review
-
Loftus E. Schoenfeld P. Sandborn W. (2002) The epidemiology and natural history of Crohn's disease in population-based patient cohorts from North America: a systematic review. Alim Pharm Ther 16: 51–60.
-
(2002)
Alim Pharm Ther
, vol.16
, pp. 51-60
-
-
Loftus, E.1
Schoenfeld, P.2
Sandborn, W.3
-
60
-
-
33847632366
-
Natalizumab for induction of remission in Crohn's disease
-
24 January DOI: 10.1002/14651858.CD006097.pub2
-
MacDonald J. McDonald J. (2007) Natalizumab for induction of remission in Crohn's disease. Cochrane Database Syst Rev. 24 January 2007. DOI: 10.1002/14651858.CD006097.pub2.
-
(2007)
Cochrane Database Syst Rev
-
-
MacDonald, J.1
McDonald, J.2
-
61
-
-
0025333699
-
Tumor necrosis factor-alpha and interferon gamma production measured at the single cell level in normal and inflamed human intestine
-
MacDonald T. Hatchings P. Choy M. Munch S. Cooke A. (1990) Tumor necrosis factor-alpha and interferon gamma production measured at the single cell level in normal and inflamed human intestine. Clin Exp Immunol 81: 301–305.
-
(1990)
Clin Exp Immunol
, vol.81
, pp. 301-305
-
-
MacDonald, T.1
Hatchings, P.2
Choy, M.3
Munch, S.4
Cooke, A.5
-
62
-
-
79751472857
-
The London position statement of the world congress of gastroenterology on biological therapy for IBD with the European Crohn's and Colitis Organisation: pregnancy and pediatrics
-
Mahadevan U. Cucchiara S. Hyams J. Steinwurz F. Nuti F. Travis S. et al. (2011) The London position statement of the world congress of gastroenterology on biological therapy for IBD with the European Crohn's and Colitis Organisation: pregnancy and pediatrics. Am J Gastroenterol 106: 214–223.
-
(2011)
Am J Gastroenterol
, vol.106
, pp. 214-223
-
-
Mahadevan, U.1
Cucchiara, S.2
Hyams, J.3
Steinwurz, F.4
Nuti, F.5
Travis, S.6
-
63
-
-
84874576191
-
Placental transfer of anti–tumor necrosis factor agents in pregnant patients with inflammatory bowel disease
-
Mahadevan U. Wolf D. Dubinsky M. Cortot A. Lee S. Siegel C. et al. (2013) Placental transfer of anti–tumor necrosis factor agents in pregnant patients with inflammatory bowel disease. Clin Gastroenterol Hepatol 11: 286–292.
-
(2013)
Clin Gastroenterol Hepatol
, vol.11
, pp. 286-292
-
-
Mahadevan, U.1
Wolf, D.2
Dubinsky, M.3
Cortot, A.4
Lee, S.5
Siegel, C.6
-
65
-
-
84879479335
-
Incidence and phenotype of inflammatory bowel disease based on results from the Asia-Pacific Crohn's and colitis epidemiology study
-
Ng S. Tang W. Ching J. Wong M. Chow C. Hui A. et al. (2013) Incidence and phenotype of inflammatory bowel disease based on results from the Asia-Pacific Crohn's and colitis epidemiology study. Gastroenterology 145: 158–165.
-
(2013)
Gastroenterology
, vol.145
, pp. 158-165
-
-
Ng, S.1
Tang, W.2
Ching, J.3
Wong, M.4
Chow, C.5
Hui, A.6
-
66
-
-
0035978533
-
A frameshift mutation in NOD 2 associated with susceptibility to Crohn's disease
-
Ogura Y. Bonen D. Inohara N. Nicolae D. Chen F. Ramos R. et al. (2001) A frameshift mutation in NOD 2 associated with susceptibility to Crohn's disease. Nature 411: 603–606.
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.2
Inohara, N.3
Nicolae, D.4
Chen, F.5
Ramos, R.6
-
69
-
-
0037043658
-
Inflammatory bowel disease
-
Podolsky D. (2002) Inflammatory bowel disease. N Engl J Med. 347: 417–429.
-
(2002)
N Engl J Med
, vol.347
, pp. 417-429
-
-
Podolsky, D.1
-
71
-
-
0018289830
-
National Cooperative Crohn's Disease Study: extraintestinal manifestations and perianal complications
-
Rankin G. Watts H. Melnyk C. Kelley. M. Jr. (1979) National Cooperative Crohn's Disease Study: extraintestinal manifestations and perianal complications. Gastroenterology 77: 914–920.
-
(1979)
Gastroenterology
, vol.77
, pp. 914-920
-
-
Rankin, G.1
Watts, H.2
Melnyk, C.3
Kelley., M.4
-
72
-
-
84875687447
-
Biologic therapy for autoimmune diseases: an update
-
Rosman Z. Shoenfeld Y. Zandman-Goddard G. (2013) Biologic therapy for autoimmune diseases: an update. BMC Med 11: 88.
-
(2013)
BMC Med
, vol.11
, pp. 88
-
-
Rosman, Z.1
Shoenfeld, Y.2
Zandman-Goddard, G.3
-
74
-
-
33745608448
-
Onercept for moderate-to-severe Crohn's disease: a randomized, double-blind, placebo-controlled trial
-
Rutgeerts P. Sandborn W. Fedorak R. Rachmilewitz D. Tarabar D. Gibson P. et al. (2006) Onercept for moderate-to-severe Crohn's disease: a randomized, double-blind, placebo-controlled trial. Clin Gastroenterol Hepatol 4: 888–893.
-
(2006)
Clin Gastroenterol Hepatol
, vol.4
, pp. 888-893
-
-
Rutgeerts, P.1
Sandborn, W.2
Fedorak, R.3
Rachmilewitz, D.4
Tarabar, D.5
Gibson, P.6
-
75
-
-
84862777782
-
Adalimumab induces and maintains mucosal healing in patients with Crohn's disease: data from the EXTEND trial
-
Rutgeerts P. van Assche G. Sandborn W. Wolf D. Geboes K. Colombel J. et al. (2012) Adalimumab induces and maintains mucosal healing in patients with Crohn's disease: data from the EXTEND trial. Gastroenterology 142: 1102–1111.
-
(2012)
Gastroenterology
, vol.142
, pp. 1102-1111
-
-
Rutgeerts, P.1
van Assche, G.2
Sandborn, W.3
Wolf, D.4
Geboes, K.5
Colombel, J.6
-
77
-
-
84888320100
-
Mucosal healing is associated with improved long-term outcome of maintenance therapy with natalizumab in Crohn's disease
-
Sakuraba A. Annunziata M. Cohen R. Hanauer S. Rubin D. (2013 b) Mucosal healing is associated with improved long-term outcome of maintenance therapy with natalizumab in Crohn's disease. Inflamm Bowel Dis 19: 2577–2583.
-
(2013)
Inflamm Bowel Dis
, vol.19
, pp. 2577-2583
-
-
Sakuraba, A.1
Annunziata, M.2
Cohen, R.3
Hanauer, S.4
Rubin, D.5
-
78
-
-
78650096816
-
Importance of disrupted intestinal barrier in inflammatory bowel diseases
-
Salim S. Soderholm J. (2011) Importance of disrupted intestinal barrier in inflammatory bowel diseases. Inflamm Bowel Dis 17: 362–381.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 362-381
-
-
Salim, S.1
Soderholm, J.2
-
81
-
-
0041823990
-
Review article: mild to moderate Crohn's disease – defining the basics for new treatment algorithm
-
Sandborn W. Feagan B. (2003) Review article: mild to moderate Crohn's disease – defining the basics for new treatment algorithm. Alim Pharm Ther 18: 263–277.
-
(2003)
Alim Pharm Ther
, vol.18
, pp. 263-277
-
-
Sandborn, W.1
Feagan, B.2
-
82
-
-
53049091561
-
A randomized trial of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease
-
Sandborn W. Feagan B. Fedorak R. Scherl E. Fleisher M. Katz S. et al. (2008) A randomized trial of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease. Gastroenterology 135: 1130–1141.
-
(2008)
Gastroenterology
, vol.135
, pp. 1130-1141
-
-
Sandborn, W.1
Feagan, B.2
Fedorak, R.3
Scherl, E.4
Fleisher, M.5
Katz, S.6
-
85
-
-
84871701834
-
Ustekinumab induction and maintenance therapy in refractory Crohn's disease
-
Sandborn W. Gasink C. Gao L. Blank M. Johanns J. Guzzo C. et al. (2012) Ustekinumab induction and maintenance therapy in refractory Crohn's disease. N Eng J Med 367: 1519–1528.
-
(2012)
N Eng J Med
, vol.367
, pp. 1519-1528
-
-
Sandborn, W.1
Gasink, C.2
Gao, L.3
Blank, M.4
Johanns, J.5
Guzzo, C.6
-
86
-
-
0034754477
-
Etanercept for active Crohn's disease: a randomized, double-blind, placebo-controlled trial
-
Sandborn W. Hanauer S. Katz S. Safdi M. Wolf D. Baerg R. et al. (2001) Etanercept for active Crohn's disease: a randomized, double-blind, placebo-controlled trial. Gastroenterology 121: 1088–1094.
-
(2001)
Gastroenterology
, vol.121
, pp. 1088-1094
-
-
Sandborn, W.1
Hanauer, S.2
Katz, S.3
Safdi, M.4
Wolf, D.5
Baerg, R.6
-
87
-
-
34249281002
-
Adalimumab for maintenance treatment of Crohn's disease: Results of the CLASSIC II trial
-
Sandborn W. Hanauer S. Rutgeerts P. Fedorak R. Lukas M. MacIntosh D. et al. (2007 b) Adalimumab for maintenance treatment of Crohn's disease: Results of the CLASSIC II trial. Gut 56: 1232–1239.
-
(2007)
Gut
, vol.56
, pp. 1232-1239
-
-
Sandborn, W.1
Hanauer, S.2
Rutgeerts, P.3
Fedorak, R.4
Lukas, M.5
MacIntosh, D.6
-
88
-
-
84907890976
-
Long-term safety and efficacy of certolizumab pegol in the treatment of Crohn's disease: 7-year results from the PRECiSE 3 study
-
Sandborn W. Lee S. Randall C. Gutierrez A. Schwartz D. Ambarkhane S. et al. (2014) Long-term safety and efficacy of certolizumab pegol in the treatment of Crohn's disease: 7-year results from the PRECiSE 3 study. Alim Pharm Ther 40: 903–916.
-
(2014)
Alim Pharm Ther
, vol.40
, pp. 903-916
-
-
Sandborn, W.1
Lee, S.2
Randall, C.3
Gutierrez, A.4
Schwartz, D.5
Ambarkhane, S.6
-
89
-
-
34347402306
-
Adalimumab induction therapy for crohn's disease previously treated with infliximab: A randomized trial
-
Sandborn W. Rutgeerts P. Enns R. Hanauer S. Colombel J. Panaccione R. et al. (2007 c) Adalimumab induction therapy for crohn's disease previously treated with infliximab: A randomized trial. Ann Int Med 146: 829–838.
-
(2007)
Ann Int Med
, vol.146
, pp. 829-838
-
-
Sandborn, W.1
Rutgeerts, P.2
Enns, R.3
Hanauer, S.4
Colombel, J.5
Panaccione, R.6
-
92
-
-
5044235159
-
Long-term treatment of rectovaginal fistulas in Crohn's disease: response to infliximab in the ACCENT II Study
-
Sands B. Blank M. Patel K. van Deventer S. (2004 b) Long-term treatment of rectovaginal fistulas in Crohn's disease: response to infliximab in the ACCENT II Study. Clin Gastroenterol Hepatol 2: 912–920.
-
(2004)
Clin Gastroenterol Hepatol
, vol.2
, pp. 912-920
-
-
Sands, B.1
Blank, M.2
Patel, K.3
van Deventer, S.4
-
93
-
-
33846184129
-
Safety and tolerability of concurrent natalizumab treatment for patients with Crohn's disease not in remission while receiving infliximab
-
Sands B. Kozarek R. Spainhour J. Barish C. Becker S. Goldberg L. et al. (2007) Safety and tolerability of concurrent natalizumab treatment for patients with Crohn's disease not in remission while receiving infliximab. Inflamm Bowel Dis 13: 2–11.
-
(2007)
Inflamm Bowel Dis
, vol.13
, pp. 2-11
-
-
Sands, B.1
Kozarek, R.2
Spainhour, J.3
Barish, C.4
Becker, S.5
Goldberg, L.6
-
94
-
-
33745775434
-
Mechanisms of disease: pathogenesis of Crohn's disease and ulcerative colitis
-
Sartor R. (2006) Mechanisms of disease: pathogenesis of Crohn's disease and ulcerative colitis. Nat Clin Pract Gastroenterol Hepatol 3: 390–407.
-
(2006)
Nat Clin Pract Gastroenterol Hepatol
, vol.3
, pp. 390-407
-
-
Sartor, R.1
-
96
-
-
24144483087
-
A randomized, placebo-controlled trial of certolizumab pegol (CDP870) for treatment of Crohn's disease
-
Schreiber S. Rutgeerts P. Fedorak R. Khaliq–Kareemi M. Kamm M. Boivin M. et al. (2005) A randomized, placebo-controlled trial of certolizumab pegol (CDP870) for treatment of Crohn's disease. Gastroenterology 129: 807–818.
-
(2005)
Gastroenterology
, vol.129
, pp. 807-818
-
-
Schreiber, S.1
Rutgeerts, P.2
Fedorak, R.3
Khaliq–Kareemi, M.4
Kamm, M.5
Boivin, M.6
-
97
-
-
0030451868
-
Incidence of inflammatory bowel disease across Europe: is there a difference between north and south? Results of the European Collaborative Study on Inflammatory Bowel Disease (EC-IBD)
-
Shivananda S. Lennard-Jones J. Logan R. Fear N. Price A. Carpenter L. et al. (1996) Incidence of inflammatory bowel disease across Europe: is there a difference between north and south? Results of the European Collaborative Study on Inflammatory Bowel Disease (EC-IBD). Gut 39: 690–697.
-
(1996)
Gut
, vol.39
, pp. 690-697
-
-
Shivananda, S.1
Lennard-Jones, J.2
Logan, R.3
Fear, N.4
Price, A.5
Carpenter, L.6
-
101
-
-
0030954732
-
A short-term study of chimeric monoclonal antibody cA 2 to tumor necrosis factor α for Crohn's disease. N
-
Targan S. Hanauer S. van Deventer S. Mayer L. Present D. Braakman T. et al. (1997) A short-term study of chimeric monoclonal antibody cA 2 to tumor necrosis factor α for Crohn's disease. N Eng J Med 337: 1029–1036.
-
(1997)
Eng J Med
, vol.337
, pp. 1029-1036
-
-
Targan, S.1
Hanauer, S.2
van Deventer, S.3
Mayer, L.4
Present, D.5
Braakman, T.6
-
102
-
-
75149116327
-
The second European evidence-based consensus on the diagnosis and management of Crohn's disease: special situations
-
van Assche G. Dignass A. Reinisch W. van der Woude C. Sturm A. de Vos M. et al. (2010) The second European evidence-based consensus on the diagnosis and management of Crohn's disease: special situations. J Crohns Colitis 4: 63–101.
-
(2010)
J Crohns Colitis
, vol.4
, pp. 63-101
-
-
van Assche, G.1
Dignass, A.2
Reinisch, W.3
van der Woude, C.4
Sturm, A.5
de Vos, M.6
-
104
-
-
84855161776
-
Switch to adalimumab in patients with Crohn's disease controlled by maintenance infliximab: prospective randomised SWITCH trial
-
van Assche G. Vermeire S. Ballet V. Gabriels F. Noman M. D'Haens G. et al. (2012) Switch to adalimumab in patients with Crohn's disease controlled by maintenance infliximab: prospective randomised SWITCH trial. Gut 61: 229–234.
-
(2012)
Gut
, vol.61
, pp. 229-234
-
-
van Assche, G.1
Vermeire, S.2
Ballet, V.3
Gabriels, F.4
Noman, M.5
D'Haens, G.6
-
105
-
-
0032730968
-
Anti-TNF antibody treatment of Crohn's disease
-
van Deventer S. (1999) Anti-TNF antibody treatment of Crohn's disease. Ann Rheum Dis 58: I114–I120.
-
(1999)
Ann Rheum Dis
, vol.58
, pp. I114-I120
-
-
van Deventer, S.1
-
107
-
-
52649134405
-
JC viral loads in patients with Crohn's disease treated with immunosuppression: can we screen for elevated risk of progressive multifocal leukoencephalopathy?
-
Verbeeck J. van Assche G. Ryding J. Wollants E. Rans K. Vermeire S. et al. (2008) JC viral loads in patients with Crohn's disease treated with immunosuppression: can we screen for elevated risk of progressive multifocal leukoencephalopathy?. Gut 57: 1393–1397.
-
(2008)
Gut
, vol.57
, pp. 1393-1397
-
-
Verbeeck, J.1
van Assche, G.2
Ryding, J.3
Wollants, E.4
Rans, K.5
Vermeire, S.6
-
108
-
-
79955562264
-
Blocking lymphocyte localization to the gastrointestinal mucosa as a therapeutic strategy for inflammatory bowel diseases
-
Villablanca E. Cassani B. von Andrian U. Mora J. (2011) Blocking lymphocyte localization to the gastrointestinal mucosa as a therapeutic strategy for inflammatory bowel diseases. Gastroenterology 140: 1776–1784.
-
(2011)
Gastroenterology
, vol.140
, pp. 1776-1784
-
-
Villablanca, E.1
Cassani, B.2
von Andrian, U.3
Mora, J.4
-
109
-
-
77950433553
-
Anti-infliximab IgE and non-IgE antibodies and induction of infusion-related severe anaphylactic reactions
-
Vultaggio A. Matucci A. Nencini F. Pratesi S. Parronchi P. Rossi O. et al. (2010) Anti-infliximab IgE and non-IgE antibodies and induction of infusion-related severe anaphylactic reactions. Allergy 65: 657–661.
-
(2010)
Allergy
, vol.65
, pp. 657-661
-
-
Vultaggio, A.1
Matucci, A.2
Nencini, F.3
Pratesi, S.4
Parronchi, P.5
Rossi, O.6
-
110
-
-
78649465120
-
Maintenance of clinical benefit in Crohn's disease patients after discontinuation of infliximab: long-term follow-up of a single centre cohort
-
Waugh A. Garg S. Matic K. Gramlich L. Wong C. Sadowski D. et al. (2010) Maintenance of clinical benefit in Crohn's disease patients after discontinuation of infliximab: long-term follow-up of a single centre cohort. Alim Pharm Ther 32: 1129–1134.
-
(2010)
Alim Pharm Ther
, vol.32
, pp. 1129-1134
-
-
Waugh, A.1
Garg, S.2
Matic, K.3
Gramlich, L.4
Wong, C.5
Sadowski, D.6
-
111
-
-
34547176642
-
Unravelling the pathogenesis of inflammatory bowel disease
-
Xavier R. Podolsky D. (2007) Unravelling the pathogenesis of inflammatory bowel disease. Nature 448: 427–434.
-
(2007)
Nature
, vol.448
, pp. 427-434
-
-
Xavier, R.1
Podolsky, D.2
-
112
-
-
84874569090
-
Effects of discontinuing anti-tumor necrosis factor therapy during pregnancy on the course of inflammatory bowel disease and neonatal exposure
-
Zelinkova Z. van der Ent C. Bruin K. van Baalen O. Vermeulen H. Smalbraak H. et al. (2013) Effects of discontinuing anti-tumor necrosis factor therapy during pregnancy on the course of inflammatory bowel disease and neonatal exposure. Clin Gastroenterol Hepatol 11: 318–321.
-
(2013)
Clin Gastroenterol Hepatol
, vol.11
, pp. 318-321
-
-
Zelinkova, Z.1
van der Ent, C.2
Bruin, K.3
van Baalen, O.4
Vermeulen, H.5
Smalbraak, H.6
-
113
-
-
84891815184
-
Inflammatory bowel disease: pathogenesis
-
Zhang Y. Li Y. (2014) Inflammatory bowel disease: pathogenesis. World J Gastroenterol 20: 91.
-
(2014)
World J Gastroenterol
, vol.20
, pp. 91
-
-
Zhang, Y.1
Li, Y.2
|