Case Report: Fatal case of disseminated BCG infection in an infant born to a mother taking infliximab for Crohn's Disease

Journal of Crohn's and Colitis

Volumn 4, Issue 5, 2010, Pages 603-605

  Cheent, Kuldeep ^a   Nolan, Jonathan ^a   Shariq, Sohail ^a   Kiho, Liina ^b   Pal, Arabinda ^a   Arnold, Jayantha ^a  

^a EALING HOSPITAL NHS TRUST   (United Kingdom)

^b ROYAL LONDON HOSPITAL   (United Kingdom)

Author keywords

BCG; Crohn's; Infliximab; Pregnancy; Vaccination

Indexed keywords

ADALIMUMAB; AZATHIOPRINE; BCG VACCINE; CERTOLIZUMAB PEGOL; CORTICOSTEROID; INFLIXIMAB; MESALAZINE; PREDNISOLONE;

ADULT; ARTICLE; BCG VACCINATION; CASE REPORT; CAUSE OF DEATH; CORTICOSTEROID THERAPY; CROHN DISEASE; DISSEMINATED BACILLE CALMETTE GUERIN INFECTION; DRUG DOSE INCREASE; FEMALE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFECTIOUS COMPLICATION; MONOTHERAPY; PREGNANCY; PREGNANT WOMAN; PRIORITY JOURNAL; RISK BENEFIT ANALYSIS; TUBERCULOSIS; VACCINATION; VAGINAL DELIVERY;

ADULT; ANTI-INFLAMMATORY AGENTS; ANTIBODIES, MONOCLONAL; BCG VACCINE; CROHN DISEASE; FATAL OUTCOME; FEMALE; HUMANS; IMMUNOSUPPRESSION; INFANT; MALE; MYCOBACTERIUM BOVIS; MYCOBACTERIUM INFECTIONS; PREGNANCY; PREGNANCY COMPLICATIONS; TUBERCULOSIS, PULMONARY; TUMOR NECROSIS FACTOR-ALPHA; VACCINATION;

EID: 77958150896     PISSN: 18739946     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.crohns.2010.05.001     Document Type: Article

References (13)

1. Lotte A., Wasz-Hockert O., Poisson N., Engbaek H., Landmann H., Quast U., Andrasofszky B., Lugosi L., Vadasz I., Mihailescu P. Second IUATLD study on complications induced by intradermal BCG-vaccination. Bull Int Union Tuberc Lung Dis 1988 June, 63(2):47-59.
2. Talbot E.A., Perkins M.D., Silva S.F., Frothingham R. Disseminated Bacille Calmette-Guerin disease after vaccination: case report and review. Clin Infect Dis 1997 June, 24(6):1139-1146.
3. Hesseling A.C., Cotton M.F., Fordham von R.C., Graham S.M., Gie R.P., Hussey G.D. Consensus statement on the revised World Health Organization recommendations for BCG vaccination in HIV-infected infants. Int J Tuberc Lung Dis 2008 December, 12(12):1376-1379.
4. Katz J.A., Antoni C., Keenan G.F., Smith D.E., Jacobs S.J., Lichtenstein G.R. Outcome of pregnancy in women receiving infliximab for the treatment of Crohn's disease and rheumatoid arthritis. Am J Gastroenterol 2004 December, 99(12):2385-2392.
5. Mahadevan U., Kane S., Sandborn W.J., Cohen R.D., Hanson K., Terdiman J.P., Binion D.G. Intentional infliximab use during pregnancy for induction or maintenance of remission in Crohn's disease. Aliment Pharmacol Ther 2005 March 15, 21(6):733-738.
6. Lichtenstein G.R., Feagan B.G., Cohen R.D., Salzberg B.A., Diamond R.H., Chen D.M., Pritchard M.L., Sandborn W.J. Serious infections and mortality in association with therapies for Crohn's disease: TREAT registry. Clin Gastroenterol Hepatol 2006 May, 4(5):621-630.
7. Dubinsky M., Abraham B., Mahadevan U. Management of the pregnant IBD patient. Inflamm Bowel Dis 2008 December, 14(12):1736-1750.
8. Vasiliauskas E.A., Church J.A., Silverman N., Barry M., Targan S.R., Dubinsky M.C. Case report: evidence for transplacental transfer of maternally administered infliximab to the newborn. Clin Gastroenterol Hepatol 2006 October, 4(10):1255-1258.
9. Mahadevan U., Church J.A. Infliximab levels in infants born to women with inflammatory bowel disease. Gastroenterology 2007, 132:A144. Ref Type: Generic.
10. Kane S., Ford J., Cohen R., Wagner C. Absence of infliximab in infants and breast milk from nursing mothers receiving therapy for Crohn's disease before and after delivery. J Clin Gastroenterol 2009 January 22.
11. Toussirot E., Wendling D. Bacillus Calmette-Guerin vaccination in a patient treated with infliximab. J Rheumatol 2005 December, 32(12):2500-2501.
12. Assche G.V., Dignass A., Reinisch W., Janneke van der Woude C., Sturm A., De Vos M., et al. The second European evidence based consensus on the diagnosis and management of Crohn's disease: special situations. Journal of Crohn's and Colitis 2010, 4:63-101.
13. Mahadevan U., Kane S. American gastroenterological association institute medical position statement on the use of gastrointestinal medications in pregnancy. Gastroenterology 2006 July, 131(1):278-282.