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Volumn 106, Issue 4, 2011, Pages 644-659

Efficacy of biological therapies in inflammatory bowel disease: Systematic review and meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; AMINOSALICYLIC ACID; AZATHIOPRINE; BUDESONIDE; CERTOLIZUMAB PEGOL; CORTICOSTEROID; INFLIXIMAB; MERCAPTOPURINE; METHOTREXATE; NATALIZUMAB; PLACEBO; PREDNISONE; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

EID: 79953801792     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1038/ajg.2011.73     Document Type: Review
Times cited : (534)

References (62)
  • 2
    • 85050704462 scopus 로고    scopus 로고
    • Crohn's disease in Olmsted County Minnesota 1940-1993: Incidence, prevalence, and survival
    • Lofus Jr EV, Silverstein MD, Sandborn WJ et al Crohn's disease in Olmsted County, Minnesota, 1940-1993: incidence, prevalence, and survival. Gastroenterology 1999;116:1161-8.
    • (1999) Gastroenterology , vol.116 , pp. 1161-8
    • Lofus Jr., E.V.1    Silverstein, M.D.2    Sandborn, W.J.3
  • 4
    • 0034026626 scopus 로고    scopus 로고
    • Ulcerative colitis in Olm-sted County Minnesota 1940-1993: Incidence, prevalence, and survival
    • Lofus Jr EV, Silverstein MD, Sandborn WJ et al Ulcerative colitis in Olm-sted County, Minnesota, 1940-1993: incidence, prevalence, and survival. Gut 2000;46:336-43.
    • (2000) Gut , vol.46 , pp. 336-43
    • Lofus Jr., E.V.1    Silverstein, M.D.2    Sandborn, W.J.3
  • 5
    • 0000206329 scopus 로고
    • An assessment of prednisone, salazopyrin, and topical hydrocortisone hemisuccinate used as out-patient treatment for ulcerative colitis
    • Lennard-Jones JE, Longmore AJ, Newell AC et al An assessment of prednisone, salazopyrin, and topical hydrocortisone hemisuccinate used as out-patient treatment for ulcerative colitis. Gut 1960; 1: 217-22.
    • (1960) Gut , vol.1 , pp. 217-22
    • Lennard-Jones, J.E.1    Longmore, A.J.2    Newell, A.C.3
  • 6
    • 0008690916 scopus 로고
    • Cortisone in ulcerative colits: Final report on a thera-peutic trial
    • Truelove SC, Witts LJ. Cortisone in ulcerative colits: final report on a thera-peutic trial. Br Med J 1955; 2: 1041-8.
    • (1955) Br Med J , vol.2 , pp. 1041-8
    • Truelove, S.C.1    Witts, L.J.2
  • 7
    • 0018290191 scopus 로고
    • National cooperative Crohn's disease study: Results of drug treatment
    • Summers RW, Switz DM, Sessions Jr JTet al National cooperative Crohn's disease study (ECCDS): results of drug treatment. Gastroenterology 1979;77:847-69. (Pubitemid 9242048)
    • (1979) Gastroenterology , vol.77 , Issue.4 II , pp. 847-869
    • Summers, R.W.1    Switz, D.M.2    Sessions Jr., J.T.3
  • 8
    • 0034903792 scopus 로고    scopus 로고
    • Te natural history of corticosteroid therapy for Infammatory bowel disease: A population-based study
    • Faubion Jr WA, Lofus Jr EV, Harmsen WS et al Te natural history of corticosteroid therapy for Infammatory bowel disease: a population-based study. Gastroenterology 2002;121:255-60.
    • (2002) Gastroenterology , vol.121 , pp. 255-60
    • Faubion Jr., W.A.1    Lofus Jr., E.V.2    Harmsen, W.S.3
  • 10
    • 0028267896 scopus 로고
    • Frequency of glucocorticoid resistance and dependency in Crohn ′s disease
    • Munkholm P Langholz E, Davidsen M et al. Frequency of glucocorticoid resistance and dependency in Crohn ′s disease. Gut 1994;35:360-2.
    • (1994) Gut , vol.35 , pp. 360-2
    • Munkholm, P.1    Langholz, E.2    Davidsen, M.3
  • 12
    • 0026531017 scopus 로고
    • Tumour necrosis factor alpha in stool as a marker of intestinal infammation
    • Braegger CP, Nicholls S, Murch SH et al. Tumour necrosis factor alpha in stool as a marker of intestinal infammation. Lancet 1992;339:89-91.
    • (1992) Lancet , vol.339 , pp. 89-91
    • Braegger, C.P.1    Nicholls, S.2    Murch, S.H.3
  • 13
    • 0025333699 scopus 로고
    • Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine
    • MacDonald TT, Hutchings P Choy MY et al Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and infamed human intestine. Clin Exp Immunol 1990;81:301-5. (Pubitemid 20242538)
    • (1990) Clinical and Experimental Immunology , vol.81 , Issue.2 , pp. 301-305
    • MacDonald, T.T.1    Hutchings, P.2    Choy, M.-Y.3    Murch, S.4    Cooke, A.5
  • 15
    • 0025912981 scopus 로고
    • Serum concentrations of tumour necrosis factor alpha in childhood chronic Infammatory bowel disease
    • Murch SH, Lamkin VA, Savage MO et al Serum concentrations of tumour necrosis factor alpha in childhood chronic Infammatory bowel disease. Gut 1991;32:913-7.
    • (1991) Gut , vol.32 , pp. 913-7
    • Murch, S.H.1    Lamkin, V.A.2    Savage, M.O.3
  • 16
    • 0031004878 scopus 로고    scopus 로고
    • Enhanced leukocyte binding by intestinal microvascular endothelial cells in inflammatory bowel disease
    • DOI 10.1053/gast.1997.v112.pm9178682
    • Binion DG, West GA, Ina K et al Enhanced leukocyte binding by intestinal microvascular endothelial cells in infammatory bowel disease. Gastroenterology 1997;112:1895-907. (Pubitemid 27240776)
    • (1997) Gastroenterology , vol.112 , Issue.6 , pp. 1895-1907
    • Binion, D.G.1    West, G.A.2    Ina, K.3    Ziats, N.P.4    Emancipator, S.N.5    Fiocchi, C.6
  • 17
    • 0031013029 scopus 로고    scopus 로고
    • Topographicdistributionofhom-ing receptors on B and T cells in human gut-associated lymphoid tissue: Relation of L-selectin and integrin alpha 4 beta 7 to naive and memory phenotypes
    • Farstad IN, Halstensen TS, Kvale D et al. Topographicdistributionofhom- ing receptors on B and T cells in human gut-associated lymphoid tissue: relation of L-selectin and integrin alpha 4 beta 7 to naive and memory phenotypes. Am J Pathol 1997;150:187-99.
    • (1997) Am J Pathol , vol.150 , pp. 187-99
    • Farstad, I.N.1    Halstensen, T.S.2    Kvale, D.3
  • 18
    • 0030947668 scopus 로고    scopus 로고
    • Treatment of ulcerative colitis in the cottontop tamarin using antibody to tumour necrosis factor alpha
    • Watkins PE, Warren BF, Stephens S et al Treatment of ulcerative colitis in the cottontop tamarin using antibody to tumour necrosis factor alpha. Gut 1997;40:628-33. (Pubitemid 27278331)
    • (1997) Gut , vol.40 , Issue.5 , pp. 628-633
    • Watkins, P.E.1    Warren, B.F.2    Stephens, S.3    Ward, P.4    Foulkes, R.5
  • 20
    • 77950150465 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha antibody for induction of remission in Crohn's disease
    • Akobeng AK, Zachos M. Tumour necrosis factor-alpha antibody for induction of remission in Crohn's disease. Cochrane Database Syst Rev 2004, CD003574.
    • (2004) Cochrane Database Syst Rev
    • Akobeng, A.K.1    Zachos, M.2
  • 21
    • 44849131569 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha antibodyfor maintenance of remission in Crohn's disease
    • Behm BW, Bickston SJ. Tumour necrosis factor-alpha antibodyfor maintenance of remission in Crohn's disease. Cochrane Database Syst Rev 2008;23:CD006893.
    • (2008) Cochrane Database Syst Rev , vol.23
    • Behm, B.W.1    Bickston, S.J.2
  • 22
    • 33845999959 scopus 로고    scopus 로고
    • McDonald JW Natalizumab for induction of remission in Crohn ′s disease
    • MacDonald JK, McDonald JW Natalizumab for induction of remission in Crohn ′s disease. Cochrane Database Syst Rev 2007;24:CD006097.
    • (2007) Cochrane Database Syst Rev , vol.24
    • MacDonald, J.K.1
  • 23
    • 33846564412 scopus 로고    scopus 로고
    • Do anti-tumor necrosis factors induce response and remission in patients with acute refractory Crohn's disease? A systematic meta-analysis of controlled clinical trials
    • DOI 10.1016/j.biopha.2006.06.022, PII S0753332206003301
    • Rahimi R Nikfar S, Abdollahi M. Do antitumour necrosis factors induce response and remission in patients with refractory Crohn ′ s disease? A systematic meta-analysis of controlled clinical trials. Biomed Pharmacother 2007; 61: 75-80. (Pubitemid 46185874)
    • (2007) Biomedicine and Pharmacotherapy , vol.61 , Issue.1 , pp. 75-80
    • Rahimi, R.1    Nikfar, S.2    Abdollahi, M.3
  • 24
    • 60349103428 scopus 로고    scopus 로고
    • Meta-analysis: The Effcacy and safety of certolizumab pegol in Crohn ′s disease
    • Shao L-M, Chen M-Y, Chen Q-Y et al. Meta-analysis: the Effcacy and safety of certolizumab pegol in Crohn ′s disease. Aliment Pharmacol Ter 2009;29:605-14.
    • (2009) Aliment Pharmacol ter , vol.29 , pp. 605-14
    • Shao, L.-M.1    Chen, M.-Y.2    Chen, Q.-Y.3
  • 26
    • 33750105599 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha blocking agents for induction of remission in ulcerative colitis
    • Lawson MM, Tomas AG, Akobeng AK. Tumour necrosis factor alpha blocking agents for induction of remission in ulcerative colitis. Cochrane Database Syst Rev 2006;19:CD005112.
    • (2006) Cochrane Database Syst Rev , vol.19
    • Lawson, M.M.1    Tomas, A.G.2    Akobeng, A.K.3
  • 27
    • 34447115672 scopus 로고    scopus 로고
    • Meta-analysis technique conf rms the effective-ness of anti-TNF-α in the management of active ulcerative colitis when adminis-tered in combination with corticosteroids
    • Rahimi R Nikfar S, Abdollahi M. Meta-analysis technique conf rms the effective-ness of anti-TNF-α in the management of active ulcerative colitis when adminis-tered in combination with corticosteroids. Med Sci Monit 2007;13:13-8.
    • (2007) Med Sci Monit , vol.13 , pp. 13-8
    • Rahimi Nikfar R, S.1    Abdollahi, M.2
  • 30
    • 0022992740 scopus 로고
    • Meta-analysis in clinical trials
    • DOI 10.1016/0197-2456(86)90046-2
    • DerSimonian R Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986;7:177-88. (Pubitemid 17189972)
    • (1986) Controlled Clinical Trials , vol.7 , Issue.3 , pp. 177-188
    • DerSimonian, R.1    Laird, N.2
  • 32
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Tegger M, Davey-Smith G, Schneider M et al Bias in meta-analysis detected by a simple, graphical test. Br Med J 1997; 315: 629-34. (Pubitemid 27387172)
    • (1997) British Medical Journal , vol.315 , Issue.7109 , pp. 629-634
    • Egger, M.1    Smith, G.D.2    Schneider, M.3    Minder, C.4
  • 33
    • 58149095512 scopus 로고    scopus 로고
    • Effcacy and safety of adalimumab for the treatment of Japanese patients with moderately to severely active Crohn's disease: Results from a randomized controlled trial
    • Hibi T, Watanabe M, Camez A et al. Effcacy and safety of adalimumab for the treatment of Japanese patients with moderately to severely active Crohn's disease: results from a randomized controlled trial. Am J Gastroenterol 2008;103 (Suppl 1s): S414-5.
    • (2008) Am J Gastroenterol , vol.103 , Issue.SUPPL. 1S
    • Hibi, T.1    Watanabe, M.2    Camez, A.3
  • 34
    • 0030954732 scopus 로고    scopus 로고
    • A short-term study of chimeric monoclonal antibody cA2 to tumour necrosis factor α for Crohn's disease
    • Targan SR, Hanauer SB, van Deventer SJH et al A short-term study of chimeric monoclonal antibody cA2 to tumour necrosis factor α for Crohn's disease. N Engl J Med 1997;337:1029-35.
    • (1997) N Engl J Med , vol.337 , pp. 1029-35
    • Targan, S.R.1    Hanauer, S.B.2    Van Deventer Sjh3
  • 39
    • 33645958908 scopus 로고    scopus 로고
    • Infiximab plus azathioprine for ster-oid-dependent Crohn's disease patients: A randomized placebo-controlled trial
    • Lemann M, Mary J-Y, Duclos B et al Infiximab plus azathioprine for ster-oid-dependent Crohn's disease patients: a randomized placebo-controlled trial. Gastroenterology 2006; 130: 1054-61.
    • (2006) Gastroenterology , vol.130 , pp. 1054-61
    • Lemann, M.1    Mary, J.-Y.2    Duclos, B.3
  • 40
    • 32044451548 scopus 로고    scopus 로고
    • Human antitumour necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: The CLAS-SIC-I trial
    • Hanauer SB, Sandborn WJ, Rutgeerts P et al Human antitumour necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLAS-SIC-I trial. Gastroenterology 2006; 130: 323-33.
    • (2006) Gastroenterology , vol.130 , pp. 323-33
    • Hanauer, S.B.1    Sandborn, W.J.2    Rutgeerts, P.3
  • 43
    • 11144318616 scopus 로고    scopus 로고
    • Intravenous CDP870, a PEGylated Fab′ fragment of a humanized antitumour necrosis factor antibody, in patients with moderate-to-severe Crohn's disease: An exploratory study
    • DOI 10.1111/j.1365-2036.2004.02285.x
    • Winter TA, Wright J, Ghosh S et al Intravenous CDP870, a pegylated Fab fragment of a humanized antitumour necrosis factor antibody in patients with moderate-to-severe Crohn ′ s disease: an exploratory study Aliment Pharmacol Ter 2004;20:1337-46. (Pubitemid 40040081)
    • (2004) Alimentary Pharmacology and Therapeutics , vol.20 , Issue.11-12 , pp. 1337-1346
    • Winter, T.A.1    Wright, J.2    Ghosh, S.3    Jahnsen, J.4    Innes, A.5    Round, P.6
  • 44
    • 0037413468 scopus 로고    scopus 로고
    • Natalizumab for active Crohn ′s disease
    • Ghosh S, Goldin E, Gordon FH et al Natalizumab for active Crohn ′s disease. N Engl J Med 2003;348:24-32.
    • (2003) N Engl J Med , vol.348 , pp. 24-32
    • Ghosh, S.1    Goldin, E.2    Gordon, F.H.3
  • 52
    • 67649662356 scopus 로고    scopus 로고
    • Adalimumab for the treat-ment of f stulas in patients with Crohn ′s disease
    • Colombel J-F, Schwartz DA, Sandborn WJ et al Adalimumab for the treat-ment of f stulas in patients with Crohn ′s disease. Gut 2009;58:940-8.
    • (2009) Gut , vol.58 , pp. 940-8
    • Colombel, J.-F.1    Schwartz, D.A.2    Sandborn, W.J.3
  • 54
    • 79953774179 scopus 로고    scopus 로고
    • Induction therapy with certolizu-mab pegol in patients with moderate to severe Crohn ′ s disease: A placebo-controlled trial
    • Sandborn W Schreiber S, Feagan B et al Induction therapy with certolizu-mab pegol in patients with moderate to severe Crohn ′ s disease: a placebo-controlled trial. Am J Gastroenterol 2010;105 (Suppl 1s): S419.
    • (2010) Am J Gastroenterol , vol.105 , Issue.SUPPL. 1S
    • Sandborn, W.1    Schreiber, S.2    Feagan, B.3
  • 55
    • 77950988234 scopus 로고    scopus 로고
    • Infiximab, azathioprine, or combination therapy for Crohn ′s disease
    • Colombel J-F, Sandborn WJ, Reinisch W et al Infiximab, azathioprine, or combination therapy for Crohn ′s disease. N Engl J Med 2010;362: 1383-95.
    • (2010) N Engl J Med , vol.362 , pp. 1383-95
    • Colombel, J.-F.1    Sandborn, W.J.2    Reinisch, W.3
  • 56
    • 0034777502 scopus 로고    scopus 로고
    • Infiximab in the treatment of severe steroid-refractory ulcerative colitis: A pilot study
    • Sands BE, Tremaine WJ, Sandborn WJ et al Infiximab in the treatment of severe, steroid-refractory ulcerative colitis: a pilot study Infamm Bowel Dis 2001;7:83-8.
    • (2001) Infamm Bowel Dis , vol.7 , pp. 83-8
    • Sands, B.E.1    Tremaine, W.J.2    Sandborn, W.J.3
  • 57
    • 0038460945 scopus 로고    scopus 로고
    • Infliximab in moderately severe glucocorticoid resistant ulcerative colitis: A randomised controlled trial
    • DOI 10.1136/gut.52.7.998
    • Probert CJ, Hearing SD, Schreiber S et al Infiximab in moderately severe glucocorticoid resistant ulcerative colitis: a randomised controlled trial. Gut 2003;52:998-1002. (Pubitemid 36765292)
    • (2003) Gut , vol.52 , Issue.7 , pp. 998-1002
    • Probert, C.S.J.1    Hearing, S.D.2    Schreiber, S.3    Kuhbacher, T.4    Ghosh, S.5    Arnott, I.D.R.6    Forbes, A.7
  • 60
    • 33646147141 scopus 로고    scopus 로고
    • Serious infections and mor-tality in association with therapies for Crohn's disease: TREAT registry
    • Lichtenstein GR, Feagan BG, Cohen RD et al Serious infections and mor-tality in association with therapies for Crohn's disease: TREAT registry Clin Gastroenterol Hepatol 2006;4:621-30.
    • (2006) Clin Gastroenterol Hepatol , vol.4 , pp. 621-30
    • Lichtenstein, G.R.1    Feagan, B.G.2    Cohen, R.D.3
  • 61
    • 53049083113 scopus 로고    scopus 로고
    • A randomized trial of methotrexate in combination with Infiximab for the treatment of Crohn's disease
    • Feagan BG, McDonald JW, Panaccione R et al A randomized trial of methotrexate in combination with Infiximab for the treatment of Crohn's disease. Gastroenterology 2008;135:294-5.
    • (2008) Gastroenterology , vol.135 , pp. 294-5
    • Feagan, B.G.1    McDonald, J.W.2    Panaccione, R.3


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