메뉴 건너뛰기




Volumn 106, Issue 4, 2011, Pages 674-684

Loss of response and need for adalimumab dose intensification in Crohn's disease: A systematic review

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; ANTIBIOTIC AGENT; CERTOLIZUMAB PEGOL; CORTICOSTEROID; INFLIXIMAB; MERCAPTOPURINE; MESALAZINE; METHOTREXATE; STEROID;

EID: 79953786419     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1038/ajg.2011.60     Document Type: Review
Times cited : (367)

References (51)
  • 1
    • 32044451548 scopus 로고    scopus 로고
    • Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: The CLASSIC-I trial
    • Hanauer SB, Sandborn WJ, Rutgeerts P et al. Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial. Gastroenterology 2006;130:323-33.
    • (2006) Gastroenterology , vol.130 , pp. 323-33
    • Hanauer, S.B.1    Sandborn, W.J.2    Rutgeerts, P.3
  • 4
    • 66949133561 scopus 로고    scopus 로고
    • Comparison of two adalimumab treatment schedule strategies for moderate-to-severe Crohn's disease: Results from the CHARM trial
    • Colombel JF, Sandborn WJ, Rutgeerts P et al Comparison of two adalimumab treatment schedule strategies for moderate-to-severe Crohn's disease: results from the CHARM trial. Am J Gastroenterol 2009; 104: 1170-9.
    • (2009) Am J Gastroenterol , vol.104 , pp. 1170-9
    • Colombel, J.F.1    Sandborn, W.J.2    Rutgeerts, P.3
  • 6
    • 75149161836 scopus 로고    scopus 로고
    • Te second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Current management
    • Dignass A, Van Assche G, Lindsay JO et al Te second European evidence-based Consensus on the diagnosis and management of Crohn's disease: current management. J Crohns Colitis 2010; 4: 28-62.
    • (2010) J Crohns Colitis , vol.4 , pp. 28-62
    • Dignass, A.1    Van Assche, G.2    Lindsay, J.O.3
  • 8
    • 70349512283 scopus 로고    scopus 로고
    • Incidence and clinical signif cance of immunogenic-ity to Infiximab in Crohn's disease: A critical systematic review
    • Cassinotti A, Travis S. Incidence and clinical signif cance of immunogenic-ity to Infiximab in Crohn's disease: a critical systematic review. Infamm Bowel Dis 2009;15:1264-75.
    • (2009) Infamm Bowel Dis , vol.15 , pp. 1264-75
    • Cassinotti, A.1    Travis, S.2
  • 9
    • 62049083383 scopus 로고    scopus 로고
    • Loss of response and requirement of Infiximab dose intensif cation in Crohn's disease: A review
    • Gisbert JP Panes J. Loss of response and requirement of Infiximab dose intensif cation in Crohn's disease: a review. Am J Gastroenterol 2009;104:760-7.
    • (2009) Am J Gastroenterol , vol.104 , pp. 760-7
    • Gisbert, J.P.1    Panes, J.2
  • 11
    • 79953769827 scopus 로고    scopus 로고
    • P089 Adalimumab induction and maintenance: Analysis of prescribed vs recommended doses among patients with Crohn's disease in the United States
    • Mackowiak J, Sederman R. P089 Adalimumab induction and maintenance: analysis of prescribed vs recommended doses among patients with Crohn's disease in the United States. J Crohns Colitis Suppl 2008;2:32.
    • (2008) J Crohns Colitis Suppl , vol.2 , pp. 32
    • MacKowiak, J.1    Sederman, R.2
  • 13
    • 79953782666 scopus 로고    scopus 로고
    • Achievement of early deep remission is associated with lower rates of weekly dosing for adalimumab-treated patients with Crohn's disease: Data from EXTEND
    • Sandborn WJ, Colombel JF, Lomax KG et al Achievement of early deep remission is associated with lower rates of weekly dosing for adalimumab-treated patients with Crohn's disease: data from EXTEND. Am J Gastroenterol 2010;105:S442.
    • (2010) Am J Gastroenterol , vol.105
    • Sandborn, W.J.1    Colombel, J.F.2    Lomax, K.G.3
  • 14
    • 78650159235 scopus 로고    scopus 로고
    • Dosage adjustment during long-term adalimumab treatment for Crohn's disease: Clinical Effcacy and pharmacoeconomics
    • Sandborn WJ, Colombel JF, Schreiber S et al Dosage adjustment during long-term adalimumab treatment for Crohn's disease: clinical Effcacy and pharmacoeconomics. Infamm Bowel Dis 2011;17:141-51.
    • (2011) Infamm Bowel Dis , vol.17 , pp. 141-51
    • Sandborn, W.J.1    Colombel, J.F.2    Schreiber, S.3
  • 15
    • 77952748486 scopus 로고    scopus 로고
    • Adalimumab sustains clinical remission and overall clinical benef t af er 2 years of therapy for Crohn's disease
    • Panaccione R, Colombel JF, Sandborn WJ et al Adalimumab sustains clinical remission and overall clinical benef t af er 2 years of therapy for Crohn's disease. Aliment Pharmacol Ter 2010;31:1296-309.
    • (2010) Aliment Pharmacol ter , vol.31 , pp. 1296-309
    • Panaccione, R.1    Colombel, J.F.2    Sandborn, W.J.3
  • 16
    • 33847079938 scopus 로고    scopus 로고
    • Adalimumab maintenance therapy for Crohn's disease with intolerance or lost response to Infiximab: An open-label study
    • Peyrin-Biroulet L, Laclotte C, Bigard MA. Adalimumab maintenance therapy for Crohn's disease with intolerance or lost response to Infiximab: an open-label study Aliment Pharmacol Ter 2007;25: 675-80.
    • (2007) Aliment Pharmacol ter , vol.25 , pp. 675-80
    • Peyrin-Biroulet, L.1    Laclotte, C.2    Bigard, M.A.3
  • 17
    • 72949099874 scopus 로고    scopus 로고
    • Prospective evaluation of anti-tumor necrosis factor therapy guided by magnetic resonance imaging for Crohn's perineal fstulas
    • Ng SC, Plamondon S, Gupta A et al Prospective evaluation of anti-tumor necrosis factor therapy guided by magnetic resonance imaging for Crohn's perineal fstulas. Am J Gastroenterol 2009;104:2973-86.
    • (2009) Am J Gastroenterol , vol.104 , pp. 2973-86
    • Ng, S.C.1    Plamondon, S.2    Gupta, A.3
  • 18
    • 70350130547 scopus 로고    scopus 로고
    • Inffuence of trough serum levels and immunogenicity on long-term outcome of adalimumab therapy in Crohn's disease
    • Karmiris K, Paintaud G, Noman M et al Inffuence of trough serum levels and immunogenicity on long-term outcome of adalimumab therapy in Crohn's disease. Gastroenterology 2009;137:1628-40.
    • (2009) Gastroenterology , vol.137 , pp. 1628-40
    • Karmiris, K.1    Paintaud, G.2    Noman, M.3
  • 19
    • 79953768606 scopus 로고    scopus 로고
    • Adalimumab is effective in the treatment of active luminal Crohn's disease and mucosal healing: A single center experience in 170 patients
    • Rizzello F, Gionchetti P, Brugnera R et al. Adalimumab is effective in the treatment of active luminal Crohn's disease and mucosal healing: a single center experience in 170 patients. Gut 2009;58 (Suppl 2): A171.
    • (2009) Gut , vol.58 , Issue.SUPPL. 2
    • Rizzello, F.1    Gionchetti, P.2    Brugnera, R.3
  • 20
    • 77950806829 scopus 로고    scopus 로고
    • Adalimumab in the treatment of active luminal and perianal Crohn's disease: A single center experience in 100 patients
    • Rizzello F, Gionchetti P, Tambasco R et al Adalimumab in the treatment of active luminal and perianal Crohn's disease: a single center experience in 100 patients. Gastroenterology 2009; 136: A-177.
    • (2009) Gastroenterology , vol.136
    • Rizzello, F.1    Gionchetti, P.2    Tambasco, R.3
  • 21
    • 84983150913 scopus 로고    scopus 로고
    • Previous non-response to Infiximab predicts early dose-escalation in adalimumab treated Crohn's disease patients
    • Bultman E, West RL, van Liere-Baron A et al. Previous non-response to Infiximab predicts early dose-escalation in adalimumab treated Crohn's disease patients. Gastroenterology 2010;138:S-701-2.
    • (2010) Gastroenterology , vol.138
    • Bultman, E.1    West, R.L.2    Van Liere-Baron, A.3
  • 22
    • 79953780874 scopus 로고    scopus 로고
    • Adalimumab in the treatment of perianal Crohn's disease: A single center in 64 patients
    • Gionchetti P, Rizzello F Tambasco R et al Adalimumab in the treatment of perianal Crohn's disease: a single center in 64 patients. Gastroenterology 2010;138:S-328.
    • (2010) Gastroenterology , vol.138
    • Gionchetti, P.1    Rizzello, F.2    Tambasco, R.3
  • 23
    • 70350510116 scopus 로고    scopus 로고
    • Effcacy of adalimumab in moderate-to-severe pediatric Crohn's disease
    • Viola F, Civitelli F Di Nardo G et al. Effcacy of adalimumab in moderate-to-severe pediatric Crohn's disease. Am J Gastroenterol 2009; 104: 2566-71.
    • (2009) Am J Gastroenterol , vol.104 , pp. 2566-71
    • Viola, F.1    Civitelli, F.2    Di Nardo, G.3
  • 24
    • 38149077059 scopus 로고    scopus 로고
    • Te use of adalimumab in the manage-ment of refractory Crohn's disease
    • Ho GT, Smith L, Aitken S et al. Te use of adalimumab in the manage-ment of refractory Crohn's disease. Aliment Pharmacol Ter 2008;27: 308-15.
    • (2008) Aliment Pharmacol ter , vol.27 , pp. 308-15
    • Ho, G.T.1    Smith, L.2    Aitken, S.3
  • 25
    • 53549083244 scopus 로고    scopus 로고
    • Immunogenicity negatively Inffuences the outcome of adalimumab treatment in Crohn's disease
    • West RL, Zelinkova Z, Wolbink GJ et al Immunogenicity negatively Inffuences the outcome of adalimumab treatment in Crohn's disease. Aliment Pharmacol Ter 2008;28:1122-6.
    • (2008) Aliment Pharmacol ter , vol.28 , pp. 1122-6
    • West, R.L.1    Zelinkova, Z.2    Wolbink, G.J.3
  • 26
    • 63149164383 scopus 로고    scopus 로고
    • Adalimumab induction and maintenance therapy for Crohn's disease. An open-label study
    • Lopez Palacios N, Mendoza JL, Taxonera C et al. Adalimumab induction and maintenance therapy for Crohn's disease. An open-label study Rev Esp EnfermDig 2008;100:676-81.
    • (2008) Rev Esp EnfermDig , vol.100 , pp. 676-81
    • Lopez Palacios, N.1    Mendoza, J.L.2    Taxonera, C.3
  • 27
    • 79953774772 scopus 로고    scopus 로고
    • Adalimumab in Crohn's disease
    • Sheridan JA, Keegan D, Slattery E et al Adalimumab in Crohn's disease. Gut 2008;57 (Suppl 2): A2564.
    • (2008) Gut , vol.57 , Issue.SUPPL. 2
    • Sheridan, J.A.1    Keegan, D.2    Slattery, E.3
  • 28
    • 58149302486 scopus 로고    scopus 로고
    • Adalimumab for Crohn's disease with intolerance or lost response to Infiximab: A 3-year single-centre expe-rience
    • Oussalah A, Babouri A, Chevaux JB et al Adalimumab for Crohn's disease with intolerance or lost response to Infiximab: a 3-year single-centre expe-rience. Aliment Pharmacol Ter 2009;29:416-23.
    • (2009) Aliment Pharmacol ter , vol.29 , pp. 416-23
    • Oussalah, A.1    Babouri, A.2    Chevaux, J.B.3
  • 29
    • 58149098406 scopus 로고    scopus 로고
    • Te safety prof le of anti-tumour necrosis factor therapy in Infammatory bowel disease in clinical prac-tice: Analysis of 620 patient-years follow-up
    • Lees CW, Ali AI, Tompson AI et al. Te safety prof le of anti-tumour necrosis factor therapy in Infammatory bowel disease in clinical prac-tice: analysis of 620 patient-years follow-up. Aliment Pharmacol Ter 2009; 29: 286-97.
    • (2009) Aliment Pharmacol ter , vol.29 , pp. 286-97
    • Lees, C.W.1    Ali, A.I.2    Tompson, A.I.3
  • 30
    • 76549096440 scopus 로고    scopus 로고
    • 2 year follow up of adalimumab therapy in patients with Crohn's disease
    • Kemp K, Dibb M, Makin AJ et al. 2 year follow up of adalimumab therapy in patients with Crohn's disease. J Crohns Colitis 2009; 3: S27-8.
    • (2009) J Crohns Colitis , vol.3
    • Kemp, K.1    Dibb, M.2    Makin, A.J.3
  • 31
    • 79953804104 scopus 로고    scopus 로고
    • Adalimumab in a clinical prac-tice\experience with human anti TNF-[alpha] therapy in tertiary clinical center
    • Bortlik M, Duricova D, Komarek V et al Adalimumab in a clinical prac-tice\experience with human anti TNF-[alpha] therapy in tertiary clinical center. Gastroenterology 2009;136:A-682.
    • (2009) Gastroenterology , vol.136
    • Bortlik, M.1    Duricova, D.2    Komarek, V.3
  • 32
    • 79953781456 scopus 로고    scopus 로고
    • Predictors and timing of adalimumab (ADA) dose escalation in patients with Crohn's disease (CD)
    • Cohen RD, Lewis JR, Turner H et al Predictors and timing of adalimumab (ADA) dose escalation in patients with Crohn's disease (CD). Gastroenterology 2009;136:A-652.
    • (2009) Gastroenterology , vol.136
    • Cohen, R.D.1    Lewis, J.R.2    Turner, H.3
  • 33
    • 79953767640 scopus 로고    scopus 로고
    • Anti-TNF therapy for Crohn's disease: Predictors of dose escalation and early discontinuation by 1 yearoftherapy
    • Naik AS, Qumseya B, Ananthakrishnan AN et al. Anti-TNF therapy for Crohn's disease: predictors of dose escalation and early discontinuation by 1 yearoftherapy Gastroenterology 2009;136:A-654.
    • (2009) Gastroenterology , vol.136
    • Naik, A.S.1    Qumseya, B.2    Ananthakrishnan, A.N.3
  • 34
    • 78249239500 scopus 로고    scopus 로고
    • Adalimumab for Crohn's disease in clinical practice at Mayo clinic: The frst 118 patients
    • Swoger JM, Lofus EV Jr, Tremaine WJ et al. Adalimumab for Crohn's disease in clinical practice at Mayo clinic: the frst 118 patients. Infamm Bowel Dis 2010;16:1912-21.
    • (2010) Infamm Bowel Dis , vol.16 , pp. 1912-21
    • Swoger, J.M.1    Lofus Jr., E.V.2    Tremaine, W.J.3
  • 35
    • 79953777670 scopus 로고    scopus 로고
    • Persistencyequals Effcacy in adalimumab patients: Preliminary report of a large single site experience
    • Wolf DC, Wolf CH. Persistencyequals Effcacy in adalimumab patients: preliminary report of a large single site experience. Gastroenterology 2010;138:S-699.
    • (2010) Gastroenterology , vol.138
    • Wolf, D.C.1    Wolf, C.H.2
  • 36
    • 79953803911 scopus 로고    scopus 로고
    • Long-term durability of response to adalimumab treatment in Crohn's disease
    • Chaparro M, Panes J, García V et al Long-term durability of response to adalimumab treatment in Crohn's disease. Gastroenterology 2010; 138:S-689.
    • (2010) Gastroenterology , vol.138
    • Chaparro, M.1    Panes, J.2    García, V.3
  • 37
    • 79953776010 scopus 로고    scopus 로고
    • Effcacy of adalimumab therapy in patients with Crohn's disease who were unresponsive to or intolerant of Infiximab: Six years of experience in a single gastroenterology center
    • Shafran I, Cangemi D, Burgunder P. Effcacy of adalimumab therapy in patients with Crohn's disease who were unresponsive to or intolerant of Infiximab: six years of experience in a single gastroenterology center. Am J Gastroenterol 2010;105:S444.
    • (2010) Am J Gastroenterol , vol.105
    • Shafran, I.1    Cangemi, D.2    Burgunder, P.3
  • 38
    • 55549126497 scopus 로고    scopus 로고
    • Safety and Effcacy of adalimumab in pediatric patients with Crohn disease
    • Wyneski MJ, Green A, Kay M et al Safety and Effcacy of adalimumab in pediatric patients with Crohn disease. J Pediatr Gastroenterol Nutr 2008;47:19-25.
    • (2008) J Pediatr Gastroenterol Nutr , vol.47 , pp. 19-25
    • Wyneski, M.J.1    Green, A.2    Kay, M.3
  • 39
    • 77949322468 scopus 로고    scopus 로고
    • Adalimumab treatment in children with refractory Crohn's disease
    • Rosenbach Y, Hartman C, Shapiro R et al. Adalimumab treatment in children with refractory Crohn's disease. Dig Dis Sci 2010;55: 747-53.
    • (2010) Dig Dis Sci , vol.55 , pp. 747-53
    • Rosenbach, Y.1    Hartman, C.2    Shapiro, R.3
  • 40
    • 59249106670 scopus 로고    scopus 로고
    • Effcacy and complications of adalimumab treatment for medically-refractory Crohn's disease: Analysis of nationwide experience in Scotland (2004-2008)
    • Ho GT, Mowat A, Potts L et al Effcacy and complications of adalimumab treatment for medically-refractory Crohn's disease: analysis of nationwide experience in Scotland (2004-2008). Aliment Pharmacol Ter 2009;29: 527-34.
    • (2009) Aliment Pharmacol ter , vol.29 , pp. 527-34
    • Ho, G.T.1    Mowat, A.2    Potts, L.3
  • 41
    • 71449114736 scopus 로고    scopus 로고
    • Te Effcacy and safety of a third anti-TNF monoclonal antibody in Crohn's disease af er failure of two other anti-TNF antibodies
    • Allez M, Vermeire S, Mozziconacci N et al Te Effcacy and safety of a third anti-TNF monoclonal antibody in Crohn's disease af er failure of two other anti-TNF antibodies. Aliment Pharmacol Ter 2010;31: 92-101.
    • (2010) Aliment Pharmacol ter , vol.31 , pp. 92-101
    • Allez, M.1    Vermeire, S.2    Mozziconacci, N.3
  • 42
    • 77950853756 scopus 로고    scopus 로고
    • Clinical experience with adalimumab in a multicenter Swiss cohort of patients with Crohn's disease
    • Nichita C, Stelle M, Vavricka et al Clinical experience with adalimumab in a multicenter Swiss cohort of patients with Crohn's disease. Digestion 2010;81:78-85.
    • (2010) Digestion , vol.81 , pp. 78-85
    • Nichita, C.1    Vavricka, S.M.2
  • 43
    • 76649143063 scopus 로고    scopus 로고
    • Survey on the use of adalimumab as maintenance therapy in Crohn's disease in England and Ireland
    • Russo EA, Iacucci M, Lindsay JO et al Survey on the use of adalimumab as maintenance therapy in Crohn's disease in England and Ireland. Eur J Gastroenterol Hepatol 2010;22:334-9.
    • (2010) Eur J Gastroenterol Hepatol , vol.22 , pp. 334-9
    • Russo, E.A.1    Iacucci, M.2    Lindsay, J.O.3
  • 44
    • 79953803526 scopus 로고    scopus 로고
    • Long term Effcacy of the second biologic in the management of Crohn's disease. A retrospective survey on an English-Irish cohort
    • Russo E, O ' Donnell S, Dearden J et al Long term Effcacy of the second biologic in the management of Crohn's disease. A retrospective survey on an English-Irish cohort. Gastroenterology 2010; 138: S-697.
    • (2010) Gastroenterology , vol.138
    • Russo, E.1    O'Donnell, S.2    Dearden, J.3
  • 45
    • 79953772586 scopus 로고    scopus 로고
    • Adalimumab for luminal and perianal Crohn's disease in real practice: A long-term multicenter study of effectiveness safety and predictors of response
    • Ormaechea JIF, Gonzalez-Lama Y, Casis B et al Adalimumab for luminal and perianal Crohn's disease in real practice: a long-term multicenter study of effectiveness, safety and predictors of response. Gastroenterology 2010;138:S-697.
    • (2010) Gastroenterology , vol.138
    • Jif, O.1    Gonzalez-Lama, Y.2    Casis, B.3
  • 46
    • 72949114290 scopus 로고    scopus 로고
    • Retrospective evaluation of the safety and effect of adalimumab therapy (RESEAT) in pediatric Crohn's disease
    • Rosh JR, Lerer T, Markowitz J et al Retrospective evaluation of the safety and effect of adalimumab therapy (RESEAT) in pediatric Crohn's disease. Am J Gastroenterol 2009;104:3042-9.
    • (2009) Am J Gastroenterol , vol.104 , pp. 3042-9
    • Rosh, J.R.1    Lerer, T.2    Markowitz, J.3
  • 47
    • 77952762804 scopus 로고    scopus 로고
    • Dosage pattern of adalimumab in real-world clinical practice and predictors of dosage increase in patients with Crohn's disease in the US
    • Lofus EV, Pan X, Zurawski P et al Dosage pattern of adalimumab in real-world clinical practice and predictors of dosage increase in patients with Crohn's disease in the US. Gastroenterology 2009;136:A-175.
    • (2009) Gastroenterology , vol.136
    • Lofus, E.V.1    Pan, X.2    Zurawski, P.3
  • 48
    • 79953802933 scopus 로고    scopus 로고
    • Observational study of treatment patterns in patients newly initiated with adalimumab or Infiximab therapy for Crohn's disease
    • Plevy S, Lu M, Yu A et al Observational study of treatment patterns in patients newly initiated with adalimumab or Infiximab therapy for Crohn's disease. Am J Gastroenterol 2009; 104: S479.
    • (2009) Am J Gastroenterol , vol.104
    • Plevy, S.1    Lu, M.2    Yu, A.3
  • 49
    • 79953804964 scopus 로고    scopus 로고
    • Predictors ofclinical response and maintenance of response in Crohn's disease: Data from CHARM
    • Rubin D, Reinisch W, Bensimon A et al Predictors ofclinical response and maintenance of response in Crohn's disease: data from CHARM. Am J Gastroenterol 2009;104:S478.
    • (2009) Am J Gastroenterol , vol.104
    • Rubin, D.1    Reinisch, W.2    Bensimon, A.3
  • 51
    • 59749102408 scopus 로고    scopus 로고
    • Inffuence of pheno-type at diagnosis and of other potential prognostic factors on the course of infammatorybowel disease
    • Tromberg-Camps MJ, DagneliePC, KesterAD et al. Inffuence of pheno-type at diagnosis and of other potential prognostic factors on the course of infammatorybowel disease. Am J Gastroenterol 2009;104:371-83.
    • (2009) Am J Gastroenterol , vol.104 , pp. 371-83
    • Tromberg-Camps, M.J.1    Kesterad, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.