Granulocyte-Colony Stimulating Factor (G-CSF) induces mechanical hyperalgesia via spinal activation of MAP kinases and PI3K in mice

Pharmacology Biochemistry and Behavior

Volumn 98, Issue 2, 2011, Pages 188-195

  Carvalho, Thacyana T ^a   Flauzino, Tamires ^a   Otaguiri, Eliane S ^a   Batistela, Ana P ^a   Zarpelon, Ana C ^a   Cunha, Thiago M ^b   Ferreira, Sérgio H ^b   Cunha, Fernando Q ^b   Verri Jr , Waldiceu A ^a  

^a STATE UNIVERSITY OF LONDRINA   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

ERK; G CSF; Hot plate; Hyperalgesia; JNK; Morphine; Nociception; Opioid; p38; Pain; PI3K; Spinal

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MORPHINE SULFATE; NALOXONE; PHOSPHATIDYLINOSITOL 3 KINASE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; STRESS ACTIVATED PROTEIN KINASE; WORTMANNIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; HYPERALGESIA; IN VIVO STUDY; MALE; MOUSE; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; SPINAL CORD;

ANDROSTADIENES; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FLAVONOIDS; GRANULOCYTE COLONY STIMULATING FACTOR, RECOMBINANT; HUMANS; HYPERALGESIA; IMIDAZOLES; INJECTIONS, SPINAL; INJECTIONS, SUBCUTANEOUS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MORPHINE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PYRIDINES; SPINAL CORD;

MUS;

EID: 78951487478     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2010.12.027     Document Type: Article

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