메뉴 건너뛰기




Volumn 8, Issue 4, 2015, Pages 287-295

Cleaved NOTCH1 expression pattern in head and neck squamous cell carcinoma is associated with NOTCH1 mutation, HPV status, and high-risk features

Author keywords

[No Author keywords available]

Indexed keywords

NOTCH1 INTRACELLULAR DOMAIN; NOTCH1 RECEPTOR; PROTEIN P53; UNCLASSIFIED DRUG; NOTCH1 PROTEIN, HUMAN; TP53 PROTEIN, HUMAN; TUMOR MARKER;

EID: 84927671117     PISSN: 19406207     EISSN: 19406215     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-14-0366     Document Type: Article
Times cited : (41)

References (50)
  • 2
    • 41449085148 scopus 로고    scopus 로고
    • Distinct risk factor profi les for human papillomavirus type 16-positive and human papillomavirus type 16-negative head and neck cancers
    • Gillison ML, D'SouzaG,Westra W, Sugar E, Xiao W, Begum S, et al. Distinct risk factor profi les for human papillomavirus type 16-positive and human papillomavirus type 16-negative head and neck cancers. J Natl Cancer Inst 2008;100:407-20.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 407-420
    • Gillison, M.L.1    D'Souza, G.2    Westra, W.3    Sugar, E.4    Xiao, W.5    Begum, S.6
  • 4
    • 80052177544 scopus 로고    scopus 로고
    • Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1
    • Agrawal N, Frederick MJ, Pickering CR, Bettegowda C, Chang K, Li RJ, et al. Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science 2011;333:1154-7.
    • (2011) Science , vol.333 , pp. 1154-1157
    • Agrawal, N.1    Frederick, M.J.2    Pickering, C.R.3    Bettegowda, C.4    Chang, K.5    Li, R.J.6
  • 6
    • 84961289657 scopus 로고    scopus 로고
    • Integrative and comparative genomic analysis of HPV-positive and HPVnegative head and neck squamous cell carcinomas
    • Seiwert TY, Zuo Z, Keck MK, Khattri A, Pedamallu CS, Stricker TP, et al. Integrative and comparative genomic analysis of HPV-positive and HPVnegative head and neck squamous cell carcinomas. Clin Cancer Res 2015;21:632-41.
    • (2015) Clin Cancer Res , vol.21 , pp. 632-641
    • Seiwert, T.Y.1    Zuo, Z.2    Keck, M.K.3    Khattri, A.4    Pedamallu, C.S.5    Stricker, T.P.6
  • 9
    • 84880281635 scopus 로고    scopus 로고
    • Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers
    • Pickering CR, Zhang J, Yoo SY, Bengtsson L, Moorthy S, Neskey DM, et al. Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers. Cancer Discov 2013;3:770-81.
    • (2013) Cancer Discov , vol.3 , pp. 770-781
    • Pickering, C.R.1    Zhang, J.2    Yoo, S.Y.3    Bengtsson, L.4    Moorthy, S.5    Neskey, D.M.6
  • 11
    • 84866925791 scopus 로고    scopus 로고
    • Molecular pathways: Context-dependent approaches to Notch targeting as cancer therapy
    • Egloff AM, Grandis JR. Molecular pathways: context-dependent approaches to Notch targeting as cancer therapy. Clin Cancer Res 2012;18: 5188-95.
    • (2012) Clin Cancer Res , vol.18 , pp. 5188-5195
    • Egloff, A.M.1    Grandis, J.R.2
  • 13
    • 50849104230 scopus 로고    scopus 로고
    • Notch tumor suppressor function
    • Dotto GP. Notch tumor suppressor function. Oncogene 2008;27:5115-23.
    • (2008) Oncogene , vol.27 , pp. 5115-5123
    • Dotto, G.P.1
  • 14
    • 84860273352 scopus 로고    scopus 로고
    • Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms
    • Sakamoto K, Fujii T, Kawachi H, Miki Y, Omura K, Morita K, et al. Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms. Lab Invest 2012;92:688-702.
    • (2012) Lab Invest , vol.92 , pp. 688-702
    • Sakamoto, K.1    Fujii, T.2    Kawachi, H.3    Miki, Y.4    Omura, K.5    Morita, K.6
  • 15
    • 84927671649 scopus 로고    scopus 로고
    • Notch1 overexpression associates with poor prognosis in human laryngeal squamous cell carcinoma
    • Li D, Dong P, Wu C, Cao P, Zhou L. Notch1 overexpression associates with poor prognosis in human laryngeal squamous cell carcinoma. Ann Otol Rhinol Laryngol 2014;123:705-10.
    • (2014) Ann Otol Rhinol Laryngol , vol.123 , pp. 705-710
    • Li, D.1    Dong, P.2    Wu, C.3    Cao, P.4    Zhou, L.5
  • 16
    • 78049473992 scopus 로고    scopus 로고
    • Association of high levels of Jagged-1 and Notch-1 expressionwith poor prognosis in head and neck cancer
    • Lin JT, Chen MK, Yeh KT, Chang CS, Chang TH, Lin CY, et al. Association of high levels of Jagged-1 and Notch-1 expressionwith poor prognosis in head and neck cancer. Ann Surg Oncol 2010;17:2976-83.
    • (2010) Ann Surg Oncol , vol.17 , pp. 2976-2983
    • Lin, J.T.1    Chen, M.K.2    Yeh, K.T.3    Chang, C.S.4    Chang, T.H.5    Lin, C.Y.6
  • 17
    • 62849127179 scopus 로고    scopus 로고
    • Relationship between vascular endothelial growth factor and Notch1 expression and lymphatic metastasis in tongue cancer
    • Joo YH, Jung CK, Kim MS, Sun DI. Relationship between vascular endothelial growth factor and Notch1 expression and lymphatic metastasis in tongue cancer. Otolaryngol Head Neck Surg 2009;140:512-8.
    • (2009) Otolaryngol Head Neck Surg , vol.140 , pp. 512-518
    • Joo, Y.H.1    Jung, C.K.2    Kim, M.S.3    Sun, D.I.4
  • 18
    • 77349109465 scopus 로고    scopus 로고
    • Expression of Stat3 and Notch1 is associated with cisplatin resistance in head and neck squamous cell carcinoma
    • Gu F, Ma Y, Zhang Z, Zhao J, Kobayashi H, Zhang L, et al. Expression of Stat3 and Notch1 is associated with cisplatin resistance in head and neck squamous cell carcinoma. Oncol Rep 2010;23:671-6.
    • (2010) Oncol Rep , vol.23 , pp. 671-676
    • Gu, F.1    Ma, Y.2    Zhang, Z.3    Zhao, J.4    Kobayashi, H.5    Zhang, L.6
  • 19
    • 70349501368 scopus 로고    scopus 로고
    • Correlation of Notch1 expression and activation to cisplatin-sensitivity of head and neck squamous cell carcinoma
    • Zhang ZP, Sun YL, Fu L, Gu F, Zhang L, Hao XS. Correlation of Notch1 expression and activation to cisplatin-sensitivity of head and neck squamous cell carcinoma. Ai Zheng 2009;28:100-3.
    • (2009) Ai Zheng , vol.28 , pp. 100-103
    • Zhang, Z.P.1    Sun, Y.L.2    Fu, L.3    Gu, F.4    Zhang, L.5    Hao, X.S.6
  • 20
    • 77951457224 scopus 로고    scopus 로고
    • Comparison of human papillomavirus in situ hybridization and p16 immunohistochemistry in the detection of human papillomavirus-associated head and neck cancer based on a prospective clinical experience
    • Singhi AD, Westra WH. Comparison of human papillomavirus in situ hybridization and p16 immunohistochemistry in the detection of human papillomavirus-associated head and neck cancer based on a prospective clinical experience. Cancer 2010;116:2166-73.
    • (2010) Cancer , vol.116 , pp. 2166-2173
    • Singhi, A.D.1    Westra, W.H.2
  • 22
    • 0025275853 scopus 로고
    • c-Ha-ras oncogene expression in immortalized human keratinocytes (HaCaT) alters growth potential in vivo but lacks correlation with malignancy
    • Boukamp P, Stanbridge EJ, Foo DY, Cerutti PA, Fusenig NE. c-Ha-ras oncogene expression in immortalized human keratinocytes (HaCaT) alters growth potential in vivo but lacks correlation with malignancy. Cancer Res 1990;50:2840-7.
    • (1990) Cancer Res , vol.50 , pp. 2840-2847
    • Boukamp, P.1    Stanbridge, E.J.2    Foo, D.Y.3    Cerutti, P.A.4    Fusenig, N.E.5
  • 23
    • 84861832789 scopus 로고    scopus 로고
    • Gene expression signatures modulated by epidermal growth factor receptor activation and their relationship to cetuximab resistance in head and neck squamous cell carcinoma
    • Fertig EJ, Ren Q, Cheng H, Hatakeyama H, Dicker AP, Rodeck U, et al. Gene expression signatures modulated by epidermal growth factor receptor activation and their relationship to cetuximab resistance in head and neck squamous cell carcinoma. BMC Genomics 2012;13:160.
    • (2012) BMC Genomics , vol.13 , pp. 160
    • Fertig, E.J.1    Ren, Q.2    Cheng, H.3    Hatakeyama, H.4    Dicker, A.P.5    Rodeck, U.6
  • 26
    • 84939893523 scopus 로고    scopus 로고
    • Predicting survival in head and neck squamous-cell carcinoma from TP53 mutation
    • Aug 10. [Epub ahead of print]
    • Masica DL, Li S, Douville C, Manola J, Ferris RL, Burtness B, et al. Predicting survival in head and neck squamous-cell carcinoma from TP53 mutation. Hum Genet. 2014 Aug 10. [Epub ahead of print].
    • (2014) Hum Genet
    • Masica, D.L.1    Li, S.2    Douville, C.3    Manola, J.4    Ferris, R.L.5    Burtness, B.6
  • 27
    • 36549010842 scopus 로고    scopus 로고
    • Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin
    • Leong KG, Niessen K, Kulic I, Raouf A, Eaves C, Pollet I, et al. Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin. J Exp Med 2007;204: 2935-48.
    • (2007) J Exp Med , vol.204 , pp. 2935-2948
    • Leong, K.G.1    Niessen, K.2    Kulic, I.3    Raouf, A.4    Eaves, C.5    Pollet, I.6
  • 28
    • 79957487931 scopus 로고    scopus 로고
    • Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells
    • Bao B, Wang Z, Ali S, Kong D, Li Y, Ahmad A, et al. Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells. Cancer Lett 2011;307:26-36.
    • (2011) Cancer Lett , vol.307 , pp. 26-36
    • Bao, B.1    Wang, Z.2    Ali, S.3    Kong, D.4    Li, Y.5    Ahmad, A.6
  • 31
    • 67649304460 scopus 로고    scopus 로고
    • Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment
    • Demehri S, Turkoz A, Kopan R. Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment. Cancer Cell 2009;16:55-66.
    • (2009) Cancer Cell , vol.16 , pp. 55-66
    • Demehri, S.1    Turkoz, A.2    Kopan, R.3
  • 32
    • 79955460636 scopus 로고    scopus 로고
    • Notch signalling in solid tumours: A little bit of everything but not all the time
    • Ranganathan P, Weaver KL, Capobianco AJ. Notch signalling in solid tumours: a little bit of everything but not all the time. Nat Rev Cancer 2011;11:338-51.
    • (2011) Nat Rev Cancer , vol.11 , pp. 338-351
    • Ranganathan, P.1    Weaver, K.L.2    Capobianco, A.J.3
  • 34
    • 75349091751 scopus 로고    scopus 로고
    • Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells
    • Charles N, Ozawa T, Squatrito M, Bleau AM, Brennan CW, Hambardzumyan D, et al. Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells. Cell Stem Cell 2010;6:141-52.
    • (2010) Cell Stem Cell , vol.6 , pp. 141-152
    • Charles, N.1    Ozawa, T.2    Squatrito, M.3    Bleau, A.M.4    Brennan, C.W.5    Hambardzumyan, D.6
  • 35
    • 84873728505 scopus 로고    scopus 로고
    • Endothelial cells promote the colorectal cancer stem cell phenotype through a soluble form of Jagged-1
    • Lu J, Ye X, Fan F, Xia L, Bhattacharya R, Bellister S, et al. Endothelial cells promote the colorectal cancer stem cell phenotype through a soluble form of Jagged-1. Cancer Cell 2013;23:171-85.
    • (2013) Cancer Cell , vol.23 , pp. 171-185
    • Lu, J.1    Ye, X.2    Fan, F.3    Xia, L.4    Bhattacharya, R.5    Bellister, S.6
  • 36
    • 84864005158 scopus 로고    scopus 로고
    • Targeting the Notch pathway: Twists and turns on the road to rational therapeutics
    • Aster JC, Blacklow SC. Targeting the Notch pathway: twists and turns on the road to rational therapeutics. J Clin Oncol 2012;30:2418-20.
    • (2012) J Clin Oncol , vol.30 , pp. 2418-2420
    • Aster, J.C.1    Blacklow, S.C.2
  • 38
    • 0025856717 scopus 로고
    • TAN- 1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
    • Ellisen LW, Bird J, West DC, Soreng AL, Reynolds TC, Smith SD, et al. TAN- 1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 1991; 66:649-61.
    • (1991) Cell , vol.66 , pp. 649-661
    • Ellisen, L.W.1    Bird, J.2    West, D.C.3    Soreng, A.L.4    Reynolds, T.C.5    Smith, S.D.6
  • 39
    • 79955915582 scopus 로고    scopus 로고
    • A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia
    • Klinakis A, Lobry C, Abdel-Wahab O, Oh P, HaenoH, Buonamici S, et al. A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia. Nature 2011;473:230-3.
    • (2011) Nature , vol.473 , pp. 230-233
    • Klinakis, A.1    Lobry, C.2    Abdel-Wahab, O.3    Oh, P.4    Haeno, H.5    Buonamici, S.6
  • 40
    • 84939871526 scopus 로고    scopus 로고
    • Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities
    • Jun 16. [Epub ahead of print]
    • Kagawa S,NatsuizakaM, Whelan KA, FacompreN,Naganuma S,Ohashi S, et al. Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities. Oncogene. 2014 Jun 16. [Epub ahead of print].
    • (2014) Oncogene
    • Kagawa, S.1    Natsuizaka, M.2    Whelan, K.A.3    Facompre, N.4    Naganuma, S.5    Ohashi, S.6
  • 41
    • 22244460522 scopus 로고    scopus 로고
    • Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling
    • Zeng Q, Li S, Chepeha DB, Giordano TJ, Li J, Zhang H, et al. Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling. Cancer Cell 2005;8: 13-23.
    • (2005) Cancer Cell , vol.8 , pp. 13-23
    • Zeng, Q.1    Li, S.2    Chepeha, D.B.3    Giordano, T.J.4    Li, J.5    Zhang, H.6
  • 42
    • 84910146191 scopus 로고    scopus 로고
    • Epigenetic modi fication at Notch responsive promoters blunts effi cacy of inducing Notch pathway reactivation after myocardial infarction
    • Felician G, Collesi C, Lusic M, Martinelli V, Dal Ferro M, Zentilin L, et al. Epigenetic modi fication at Notch responsive promoters blunts effi cacy of inducing Notch pathway reactivation after myocardial infarction. Circ Res 2014;115:636-49.
    • (2014) Circ Res , vol.115 , pp. 636-649
    • Felician, G.1    Collesi, C.2    Lusic, M.3    Martinelli, V.4    Dal Ferro, M.5    Zentilin, L.6
  • 43
    • 3342967780 scopus 로고    scopus 로고
    • Modulation of Notch signaling by mastermind-like (MAML) transcriptional co-activators and their involvement in tumorigenesis
    • Wu L, Griffin JD. Modulation of Notch signaling by mastermind-like (MAML) transcriptional co-activators and their involvement in tumorigenesis. Semin Cancer Biol 2004;14:348-56.
    • (2004) Semin Cancer Biol , vol.14 , pp. 348-356
    • Wu, L.1    Griffin, J.D.2
  • 44
    • 0036713311 scopus 로고    scopus 로고
    • Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/ E7 expression and late steps of malignant transformation
    • Talora C, Sgroi DC, Crum CP, Dotto GP. Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/ E7 expression and late steps of malignant transformation. Genes Dev 2002;16:2252-63.
    • (2002) Genes Dev , vol.16 , pp. 2252-2263
    • Talora, C.1    Sgroi, D.C.2    Crum, C.P.3    Dotto, G.P.4
  • 45
    • 16244418366 scopus 로고    scopus 로고
    • Constitutively active Notch1 induces growth arrest of HPV-positive cervical cancer cells via separate signaling pathways
    • Talora C, Cialfi S, Segatto O, Morrone S, Kim Choi J, Frati L, et al. Constitutively active Notch1 induces growth arrest of HPV-positive cervical cancer cells via separate signaling pathways. Exp Cell Res 2005;305:343-54.
    • (2005) Exp Cell Res , vol.305 , pp. 343-354
    • Talora, C.1    Cialfi, S.2    Segatto, O.3    Morrone, S.4    Kim Choi, J.5    Frati, L.6
  • 46
    • 0037362373 scopus 로고    scopus 로고
    • HPV16 E6 and E7 oncoproteins regulate Notch-1 expression and cooperate to induce transformation
    • Weijzen S, Zlobin A, Braid M, Miele L, Kast WM. HPV16 E6 and E7 oncoproteins regulate Notch-1 expression and cooperate to induce transformation. J Cell Physiol 2003;194:356-62.
    • (2003) J Cell Physiol , vol.194 , pp. 356-362
    • Weijzen, S.1    Zlobin, A.2    Braid, M.3    Miele, L.4    Kast, W.M.5
  • 48
    • 33947166199 scopus 로고    scopus 로고
    • Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases
    • Lefort K, Mandinova A, Ostano P, Kolev V, Calpini V, Kolfschoten I, et al. Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases. Genes Dev 2007;21:562-77.
    • (2007) Genes Dev , vol.21 , pp. 562-577
    • Lefort, K.1    Mandinova, A.2    Ostano, P.3    Kolev, V.4    Calpini, V.5    Kolfschoten, I.6
  • 49
    • 33747014859 scopus 로고    scopus 로고
    • Growth suppression induced by Notch1 activation involves Wnt-beta-catenin down-regulation in human tongue carcinoma cells
    • Duan L, Yao J, Wu X, Fan M. Growth suppression induced by Notch1 activation involves Wnt-beta-catenin down-regulation in human tongue carcinoma cells. Biol Cell 2006;98:479-90.
    • (2006) Biol Cell , vol.98 , pp. 479-490
    • Duan, L.1    Yao, J.2    Wu, X.3    Fan, M.4
  • 50
    • 67749093259 scopus 로고    scopus 로고
    • Crosstalk of Notch with p53 and p63 in cancer growth control
    • Dotto GP. Crosstalk of Notch with p53 and p63 in cancer growth control. Nat Rev Cancer 2009;9:587-95.
    • (2009) Nat Rev Cancer , vol.9 , pp. 587-595
    • Dotto, G.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.