Indolinyl-thiazole based inhibitors of scavenger receptor-BI (SR-BI)-mediated lipid transport

ACS Medicinal Chemistry Letters

Volumn 6, Issue 4, 2015, Pages 375-380

  Dockendorff, Chris ^a,b   Faloon, Patrick W ^a   Yu, Miao ^c   Youngsaye, Willmen ^a   Penman, Marsha ^c   Nieland, Thomas J F ^a,c   Nag, Partha P ^a   Lewis, Timothy A ^a   Pu, Jun ^a   Bennion, Melissa ^a   Negri, Joseph ^a   Paterson, Conor ^a   Lam, Garrett ^a   Dandapani, Sivaraman ^a   Perez, José R ^a   Munoz, Benito ^a   Palmer, Michelle A ^a   Schreiber, Stuart L ^a,d   Krieger, Monty ^c  

^a BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^b Marquette University   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

HCV; HDL receptor; HTS; indoline; ML278; MLP; reverse cholesterol transport; SR BI inhibitor; thiazole

Indexed keywords

HIGH DENSITY LIPOPROTEIN RECEPTOR; PROTEIN INHIBITOR; SCAVENGER RECEPTOR BI INHIBITOR; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CHO CELL LINE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DRUG UPTAKE; FEMALE; HUMAN; IC50; IN VITRO STUDY; IN VIVO STUDY; LIPID SOLUBILITY; LIPOPROTEIN METABOLISM; LIVER MICROSOME; MOUSE; NONHUMAN; NUCLEOPHILICITY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

HEPATITIS C VIRUS;

EID: 84927666208     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml500154q     Document Type: Article

References (30)

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