Glycine dimerization motif in the N-terminal transmembrane domain of the high density lipoprotein receptor SR-BI required for normal receptor oligomerization and lipid transport

Journal of Biological Chemistry

Volumn 286, Issue 21, 2011, Pages 18452-18464

  Gaidukov, Leonid ^a   Nager, Andrew R ^a   Xu, Shangzhe ^a   Penman, Marsha ^a   Krieger, Monty ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERY; ANTIBODY BINDING; CELL SURFACES; CLASS B; COOPERATIVITY; HIGH DENSITY LIPOPROTEIN; HIGH-DENSITY LIPOPROTEINS; HOMODIMERIZATION; INTEGRAL MEMBRANE PROTEINS; LATTICE EFFECT; LIPID TRANSPORT; N-TERMINALS; SCAVENGER RECEPTOR; STERIC INTERFERENCE; SURFACE EXPRESSION; TRANS-MEMBRANE DOMAINS; TRANSMEMBRANES; TRIPLE MUTANTS;

ACTIVATION ANALYSIS; CELL MEMBRANES; DIMERIZATION; OLIGOMERIZATION; OLIGOMERS;

AMINO ACIDS;

GLYCINE; SCAVENGER RECEPTOR BI;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIGEN BINDING; ARTICLE; CONTROLLED STUDY; CROSS LINKING; DIMERIZATION; FLOW CYTOMETRY; GENE MUTATION; GENETIC VARIABILITY; IMMUNOPRECIPITATION; LIPID TRANSPORT; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS;

AMINO ACID MOTIFS; AMINO ACID SUBSTITUTION; ANIMALS; BIOLOGICAL TRANSPORT; CERCOPITHECUS AETHIOPS; CHO CELLS; COS CELLS; CRICETINAE; CRICETULUS; HUMANS; LIPOPROTEINS, HDL; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; MICE; MUTATION, MISSENSE; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, SCAVENGER; RECOMBINANT FUSION PROTEINS; SCAVENGER RECEPTORS, CLASS B;

EID: 79956300663     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.229872     Document Type: Article

References (88)

1. Acton, S., Rigotti, A., Landschulz, K. T., Xu, S., Hobbs, H. H., and Krieger, M. (1996) Science 271, 518-520
2. Rigotti, A., Miettinen, H. E., and Krieger, M. (2003) Endocr. Rev. 24, 357-387
3. Ji, Y., Jian, B., Wang, N., Sun, Y., Moya, M. L., Phillips, M. C., Rothblat, G. H., Swaney, J. B., and Tall, A. R. (1997) J. Biol. Chem. 272, 20982-20985
4. Hatzopoulos, A. K., Rigotti, A., Rosenberg, R. D., and Krieger, M. (1998) J. Lipid Res. 39, 495-508
5. Yuhanna, I. S., Zhu, Y., Cox, B. E., Hahner, L. D., Osborne-Lawrence, S., Lu, P., Marcel, Y. L., Anderson, R. G., Mendelsohn, M. E., Hobbs, H. H., and Shaul, P. W. (2001) Nat. Med. 7, 853-857
6. Uittenbogaard, A., Shaul, P. W., Yuhanna, I. S., Blair, A., and Smart, E. J. (2000) J. Biol. Chem. 275, 11278-11283
7. Krieger, M. (1999) Annu. Rev. Biochem. 68, 523-558
8. Rothblat, G. H., and Phillips, M. C. (2010) Curr. Opin. Lipidol. 21, 229-238
9. Glomset, J. A. (1968) J. Lipid Res. 9, 155-167
10. Rigotti, A., Trigatti, B. L., Penman, M., Rayburn, H., Herz, J., and Krieger, M. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 12610-12615
11. Teslovich, T. M., Musunuru, K., Smith, A. V., Edmondson, A. C., Stylianou, I. M., Koseki, M., Pirruccello, J. P., Ripatti, S., Chasman, D. I., Willer, C. J., Johansen, C. T., Fouchier, S. W., Isaacs, A., Peloso, G. M., Barbalic, M., Ricketts, S. L., Bis, J. C., Aulchenko, Y. S., Thorleifsson, G., Feitosa, M. F., Chambers, J., Orho-Melander, M., Melander, O., Johnson, T., Li, X., Guo, X., Li, M., Shin Cho, Y., Jin Go, M., Jin Kim, Y., Lee, J. Y., Park, T., Kim, K., Sim, X., Twee-Hee Ong, R., Croteau-Chonka, D. C., Lange, L. A., Smith, J. D., Song, K., Hua Zhao, J., Yuan, X., Luan, J., Lamina, C., Ziegler, A., Zhang, W., Zee, R. Y., Wright, A. F., Witteman, J. C., Wilson, J. F., Willemsen, G., Wichmann, H. E., Whitfield, J. B., Waterworth, D. M., Wareham, N. J., Waeber, G., Vollenweider, P., Voight, B. F., Vitart, V., Uitterlinden, A. G., Uda, M., Tuomilehto, J., Thompson, J. R., Tanaka, T., Surakka, I., Stringham, H. M., Spector, T. D., Soranzo, N., Smit, J. H., Sinisalo, J., Silander, K., Sijbrands, E. J., Scuteri, A., Scott, J., Schlessinger, D., Sanna, S., Salomaa, V., Saharinen, J., Sabatti, C., Ruokonen, A., Rudan, I., Rose, L. M., Roberts, R., Rieder, M., Psaty, B. M., Pramstaller, P. P., Pichler, I., Perola, M., Penninx, B. W., Pedersen, N. L., Pattaro, C., Parker, A. N., Pare, G., Oostra, B. A., O'Donnell, C. J., Nieminen, M. S., Nickerson, D. A., Montgomery, G. W., Meitinger, T., McPherson, R., McCarthy, M. I., McArdle, W., Masson, D., Martin, N. G., Marroni, F., Mangino, M., Magnusson, P. K., Lucas, G., Luben, R., Loos, R. J., Lokki, M. L., Lettre, G., Langenberg, C., Launer, L. J., Lakatta, E. G., Laaksonen, R., Kyvik, K. O., Kronenberg, F., König, I. R., Khaw, K. T., Kaprio, J., Kaplan, L. M., Johansson, A., Jarvelin, M. R., Janssens, A. C., Ingelsson, E., Igl, W., Kees Hovingh, G., Hottenga, J. J., Hofman, A., Hicks, A. A., Hengstenberg, C., Heid, I. M., Hayward, C., Havulinna, A. S., Hastie, N. D., Harris, T. B., Haritunians, T., Hall, A. S., Gyllensten, U., Guiducci, C., Groop, L. C., Gonzalez, E., Gieger, C., Freimer, N. B., Ferrucci, L., Erdmann, J., Elliott, P., Ejebe, K. G., Döring, A., Dominiczak, A. F., Demissie, S., Deloukas, P., de Geus, E. J., de Faire, U., Crawford, G., Collins, F. S., Chen, Y. D., Caulfield, M. J., Campbell, H., Burtt, N. P., Bonnycastle, L. L., Boomsma, D. I., Boekholdt, S. M., Bergman, R. N., Barroso, I., Bandinelli, S., Ballantyne, C. M., Assimes, T. L., Quertermous, T., Altshuler, D., Seielstad, M., Wong, T. Y., Tai, E. S., Feranil, A. B., Kuzawa, C. W., Adair, L. S., Taylor, H. A., Jr., Borecki, I. B., Gabriel, S. B., Wilson, J. G., Holm, H., Thorsteinsdottir, U., Gudnason, V., Krauss, R. M., Mohlke, K. L., Ordovas, J. M., Munroe, P. B., Kooner, J. S., Tall, A. R., Hegele, R. A., Kastelein, J. J., Schadt, E. E., Rotter, J. I., Boerwinkle, E., Strachan, D. P., Mooser, V., Stefansson, K., Reilly, M. P., Samani, N. J., Schunkert, H., Cupples, L. A., Sandhu, M. S., Ridker, P. M., Rader, D. J., van Duijn, C. M., Peltonen, L., Abecasis, G. R., Boehnke, M., and Kathiresan, S. (2010) Nature 466, 707-713
12. Vergeer, M., Korporaal, S. J., Franssen, R., Meurs, I., Out, R., Hovingh, G. K., Hoekstra, M., Sierts, J. A., Dallinga-Thie, G. M., Motazacker, M. M., Holleboom, A. G., Van Berkel, T. J., Kastelein, J. J., Van Eck, M., and Kuivenhoven, J. A. (2011) N. Engl. J. Med. 364, 136-145
13. Gordon, T., Castelli, W. P., Hjortland, M. C., Kannel, W. B., and Dawber, T. R. (1977) Am. J. Med. 62, 707-714
14. Miller, G. J., and Miller, N. E. (1975) Lancet 1, 16-19
15. Gordon, D. J., Probstfield, J. L., Garrison, R. J., Neaton, J. D., Castelli, W. P., Knoke, J. D., Jacobs, D. R., Jr., Bangdiwala, S., and Tyroler, H. A. (1989) Circulation 79, 8-15
16. Kozarsky, K. F., Donahee, M. H., Glick, J. M., Krieger, M., and Rader, D. J. (2000) Arterioscler. Thromb. Vasc. Biol. 20, 721-727
17. Arai, T., Wang, N., Bezouevski, M., Welch, C., and Tall, A. R. (1999) J. Biol. Chem. 274, 2366-2371
18. Ueda, Y., Gong, E., Royer, L., Cooper, P. N., Francone, O. L., and Rubin, E. M. (2000) J. Biol. Chem. 275, 20368-20373
19. Trigatti, B., Rayburn, H., Viñals, M., Braun, A., Miettinen, H., Penman, M., Hertz, M., Schrenzel, M., Amigo, L., Rigotti, A., and Krieger, M. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 9322-9327
20. Huszar, D., Varban, M. L., Rinninger, F., Feeley, R., Arai, T., Fairchild- Huntress, V., Donovan, M. J., and Tall, A. R. (2000) Arterioscler. Thromb. Vasc. Biol. 20, 1068-1073
21. Braun, A., Trigatti, B. L., Post, M. J., Sato, K., Simons, M., Edelberg, J. M., Rosenberg, R. D., Schrenzel, M., and Krieger, M. (2002) Circ. Res. 90, 270-276
22. Braun, A., Zhang, S., Miettinen, H. E., Ebrahim, S., Holm, T. M., Vasile, E., Post, M. J., Yoerger, D. M., Picard, M. H., Krieger, J. L., Andrews, N. C., Simons, M., and Krieger, M. (2003) Proc. Natl. Acad. Sci. U.S.A. 100, 7283-7288
23. Vega, M. A., Seguí-Real, B., García, J. A., Calés, C., Rodríguez, F., Vanderkerckhove, J., and Sandoval, I. V. (1991) J. Biol. Chem. 266, 16818-16824
24. Franc, N. C., Dimarcq, J. L., Lagueux, M., Hoffmann, J., and Ezekowitz, R. A. (1996) Immunity 4, 431-443
25. Greenwalt, D. E., Lipsky, R. H., Ockenhouse, C. F., Ikeda, H., Tandon, N. N., and Jamieson, G. A. (1992) Blood 80, 1105-1115
26. Landschulz, K. T., Pathak, R. K., Rigotti, A., Krieger, M., and Hobbs, H. H. (1996) J. Clin. Investig. 98, 984-995
27. Williams, D. L., de La Llera-Moya, M., Thuahnai, S. T., Lund-Katz, S., Connelly, M. A., Azhar, S., Anantharamaiah, G. M., and Phillips, M. C. (2000) J. Biol. Chem. 275, 18897-18904
28. Reaven, E., Cortez, Y., Leers-Sucheta, S., Nomoto, A., and Azhar, S. (2004) J. Lipid Res. 45, 513-528
29. Sahoo, D., Darlington, Y. F., Pop, D., Williams, D. L., and Connelly, M. A. (2007) Biochim. Biophys. Acta 1771, 807-817
30. Azhar, S., Nomoto, A., and Reaven, E. (2002) J. Lipid Res. 43, 861-871
31. Sahoo, D., Peng, Y., Smith, J. R., Darlington, Y. F., and Connelly, M. A. (2007) Biochim. Biophys. Acta 1771, 818-829
32. Nieland, T. J., Xu, S., Penman, M., and Krieger, M. (2011) Biochemistry 50, 1818-1830
33. de Meyts, P., Roth, J., Neville, D. M., Jr., Gavin, J. R., 3rd, and Lesniak, M. A. (1973) Biochem. Biophys. Res. Commun. 55, 154-161
34. DeMeyts, P., Bainco, A. R., and Roth, J. (1976) J. Biol. Chem. 251, 1877-1888
35. Limbird, L. E. (2005) Cell Surface Receptors: a Short Course on Theory and Methods, pp. 113-114, Springer, New York
36. Glass, C., Pittman, R. C., Weinstein, D. B., and Steinberg, D. (1983) Proc. Natl. Acad. Sci. U.S.A. 80, 5435-5439
37. Stein, Y., Dabach, Y., Hollander, G., Halperin, G., and Stein, O. (1983) Biochim. Biophys. Acta 752, 98-105
38. Goldstein, J. L., and Brown, M. S. (2009) Arterioscler. Thromb. Vasc. Biol. 29, 431-438
39. Liu, T., Krieger, M., Kan, H. Y., and Zannis, V. I. (2002) J. Biol. Chem. 277, 21576-21584
40. Gu, X., Kozarsky, K., and Krieger, M. (2000) J. Biol. Chem. 275, 29993-30001
41. Connelly, M. A., Klein, S. M., Azhar, S., Abumrad, N. A., and Williams, D. L. (1999) J. Biol. Chem. 274, 41-47
42. Gu, X., Trigatti, B., Xu, S., Acton, S., Babitt, J., and Krieger, M. (1998) J. Biol. Chem. 273, 26338-26348
43. Mackenzie, K. R. (2006) Chem. Rev. 106, 1931-1977
44. Moore, D. T., Berger, B. W., and DeGrado, W. F. (2008) Structure 16, 991-1001
45. Senes, A., Engel, D. E., and DeGrado, W. F. (2004) Curr. Opin. Struct. Biol. 14, 465-479
46. Ebie, A. Z., and Fleming, K. G. (2007) J. Mol. Biol. 366, 517-524
47. Li, E., and Hristova, K. (2006) Biochemistry 45, 6241-6251
48. Constantinescu, S. N., Keren, T., Socolovsky, M., Nam, H., Henis, Y. I., and Lodish, H. F. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 4379-4384
49. Schnell, J. R., and Chou, J. J. (2008) Nature 451, 591-595
50. Stouffer, A. L., Acharya, R., Salom, D., Levine, A. S., Di Costanzo, L., Soto, C. S., Tereshko, V., Nanda, V., Stayrook, S., and DeGrado, W. F. (2008) Nature 451, 596-599
51. Lau, T. L., Kim, C., Ginsberg, M. H., and Ulmer, T. S. (2009) EMBO J. 28, 1351-1361
52. Luo, B. H., Carman, C. V., Takagi, J., and Springer, T. A. (2005) Proc. Natl. Acad. Sci. U.S.A. 102, 3679-3684
53. Mendrola, J. M., Berger, M. B., King, M. C., and Lemmon, M. A. (2002) J. Biol. Chem. 277, 4704-4712
54. Li, W., Metcalf, D. G., Gorelik, R., Li, R., Mitra, N., Nanda, V., Law, P. B., Lear, J. D., Degrado, W. F., and Bennett, J. S. (2005) Proc. Natl. Acad. Sci. U.S.A. 102, 1424-1429
55. Chung, B. H., Wilkinson, T., Geer, J. C., and Segrest, J. P. (1980) J. Lipid Res. 21, 284-291
56. Patsch, J. R., and Patsch, W. (1986) Methods Enzymol. 129, 3-26
57. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. (1951) J. Biol. Chem. 193, 265-275
58. Goldstein, J. L., Basu, S. K., and Brown, M. S. (1983) Methods Enzymol. 98, 241-260
59. Gwynne, J. T., and Mahaffee, D. D. (1989) J. Biol. Chem. 264, 8141-8150
60. Kingsley, D. M., and Krieger, M. (1984) Proc. Natl. Acad. Sci. U.S.A. 81, 5454-5458
61. Gu, X., Lawrence, R., and Krieger, M. (2000) J. Biol. Chem. 275, 9120-9130
62. Guo, Q., Penman, M., Trigatti, B. L., and Krieger, M. (1996) J. Biol. Chem. 271, 11191-11196
63. Pittman, R. C., Knecht, T. P., Rosenbaum, M. S., and Taylor, C. A., Jr. (1987) J. Biol. Chem. 262, 2443-2450
64. Lemmon, M. A., Flanagan, J. M., Hunt, J. F., Adair, B. D., Bormann, B. J., Dempsey, C. E., and Engelman, D. M. (1992) J. Biol. Chem. 267, 7683-7689
65. Riek, R. P., Finch, A. A., Begg, G. E., and Graham, R. M. (2008) Mol. Pharmacol. 73, 1092-1104
66. Lear, J. D., Stouffer, A. L., Gratkowski, H., Nanda, V., and Degrado, W. F. (2004) Biophys. J. 87, 3421-3429
67. Senes, A., Gerstein, M., and Engelman, D. M. (2000) J. Mol. Biol. 296, 921-936
68. Archibald, K., Perry, M. J., Molnár, E., and Henley, J. M. (1998) Neuropharmacology 37, 1345-1353
69. Salhany, J. M., and Sloan, R. L. (1989) Biochem. Biophys. Res. Commun. 159, 1337-1344
70. Babitt, J., Trigatti, B., Rigotti, A., Smart, E. J., Anderson, R. G., Xu, S., and Krieger, M. (1997) J. Biol. Chem. 272, 13242-13249
71. Viñals, M., Xu, S., Vasile, E., and Krieger, M. (2003) J. Biol. Chem. 278, 5325-5332
72. Goetz, H., Kuschel, M., Wulff, T., Sauber, C., Miller, C., Fisher, S., and Woodward, C. (2004) J. Biochem. Biophys. Methods 60, 281-293
73. Schouten, D., Kleinherenbrink-Stins, M. F., Brouwer, A., Knook, D. L., Kamps, J. A., Kuiper, J., and van Berkel, T. J. (1990) Arteriosclerosis 10, 1127-1135
74. Monod, J., Wyman, J., and Changeux, J. P. (1965) J. Mol. Biol. 12, 88-118
75. Levitzki, A., and Koshland, D. E., Jr. (1969) Proc. Natl. Acad. Sci. U.S.A. 62, 1121-1128
76. Koshland, D. E., Jr. (1996) Curr. Opin. Struct. Biol. 6, 757-761
77. De Meyts, P., Gauguin, L., Svendsen, A. M., Sarhan, M., Knudsen, L., Nøhr, J., and Kiselyov, V. V. (2009) Ann. N.Y. Acad. Sci. 1160, 45-53
78. De Meyts, P. (2008) Trends Biochem. Sci. 33, 376-384
79. Macdonald, J. L., and Pike, L. J. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 112-117
80. Alvarado, D., Klein, D. E., and Lemmon, M. A. (2010) Cell 142, 568-579
81. McGhee, J. D., and von Hippel, P. H. (1974) J. Mol. Biol. 86, 469-489
82. Sackett, D. L., and Saroff, H. A. (1996) FEBS Lett. 397, 1-6
83. Stankowski, S. (1983) Biochim. Biophys. Acta 735, 341-351
84. Stankowski, S. (1983) Biochim. Biophys. Acta 735, 352-360
85. Chappell, D. A., Fry, G. L., Waknitz, M. A., and Berns, J. J. (1991) J. Biol. Chem. 266, 19296-19302
86. Hardy, M. R., Townsend, R. R., Parkhurst, S. M., and Lee, Y. C. (1985) Biochemistry 24, 22-28
87. Ashkenas, J., Penman, M., Vasile, E., Acton, S., Freeman, M., and Krieger, M. (1993) J. Lipid Res. 34, 983-1000
88. Peng, Y., Akmentin, W., Connelly, M. A., Lund-Katz, S., Phillips, M. C., and Williams, D. L. (2004) Mol. Biol. Cell 15, 384-396