Solamargine inhibits migration and invasion of human hepatocellular carcinoma cells through down-regulation of matrix metalloproteinases 2 and 9 expression and activity

Toxicology in Vitro

Volumn 29, Issue 5, 2015, Pages 893-900

  Sani, Iman Karimi ^a   Marashi, Seyed Hassan ^a   Kalalinia, Fatemeh ^b  

^a FERDOWSI UNIVERSITY OF MASHHAD   (Iran)

^b MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Human hepatocellular carcinoma; Invasion; Matrix metalloproteinases; Metastasis; Migration; Solamargine

Indexed keywords

GELATINASE A; GELATINASE B; SOLAMARGINE; ANTINEOPLASTIC AGENT; BETA-SOLAMARINE; MMP2 PROTEIN, HUMAN; MMP9 PROTEIN, HUMAN; SOLANUM ALKALOID;

ARTICLE; CELL INVASION; CELL MIGRATION ASSAY; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG STRUCTURE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; METASTASIS; MIGRATION INHIBITION; MTT ASSAY; PROTEIN EXPRESSION; TUMOR INVASION; WESTERN BLOTTING; WOUND HEALING; ZYMOGRAPHY; CELL MOTION; DRUG EFFECTS; HEPG2 CELL LINE; LIVER TUMOR; METABOLISM;

SOLANUM NIGRUM;

ANTINEOPLASTIC AGENTS; CARCINOMA, HEPATOCELLULAR; CELL MOVEMENT; DOWN-REGULATION; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; SOLANACEOUS ALKALOIDS;

EID: 84927665701     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2015.03.012     Document Type: Article

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