VCLAMPs-an intimate link between vacuoles and mitochondria

Current Opinion in Cell Biology

Volumn 35, Issue , 2015, Pages 30-36

  Ungermann, Christian ^a  

^a UNIVERSITY OF OSNABRÜCK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; MEMBRANE PROTEIN;

AUTOPHAGY; BIOGENESIS; CELL COMMUNICATION AND CELL CONTACT; CELL FUNCTION; CELL MEMBRANE; CELL MEMBRANE TRANSPORT; CELL VACUOLE; CELL VACUOLE MITOCHONDRIAL PATCH; CYTOSOL; ENDOPLASMIC RETICULUM; LIPID TRANSPORT; MELANOSOME; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NONHUMAN; PATCH CLAMP TECHNIQUE; PRIORITY JOURNAL; REVIEW; YEAST CELL; ANIMAL; ENDOSOME; HUMAN; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; ENDOPLASMIC RETICULUM; ENDOSOMES; HUMANS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; VACUOLES;

EID: 84927619489     PISSN: 09550674     EISSN: 18790410     Source Type: Journal    
DOI: 10.1016/j.ceb.2015.03.006     Document Type: Review

References (54)

1. Soubannier V., McLelland G.-L., Zunino R., Braschi E., Rippstein P., Fon E.A., Mcbride H.M. A vesicular transport pathway shuttles cargo from mitochondria to lysosomes. Curr Biol 2012, 22:135-141.
2. Sugiura A., McLelland G.L., Fon E.A., McBride H.M. A new pathway for mitochondrial quality control: mitochondrial-derived vesicles. EMBO J 2014, 33:2142-2156.
3. Sojo V., Pomiankowski A., Lane N. A bioenergetic basis for membrane divergence in archaea and bacteria. PLoS Biol 2014, 12:e1001926.
4. Osman C., Voelker D.R., Langer T. Making heads or tails of phospholipids in mitochondria. J Cell Biol 2011, 192:7-16.
5. Copeland D.E., Dalton A.J. An association between mitochondria and the endoplasmic reticulum in cells of the pseudobranch gland of a teleost. J Biophys Biochem Cytol 1959, 5:393-396.
6. Achleitner G., Gaigg B., Krasser A., Kainersdorfer E., Kohlwein S.D., Perktold A., Zellnig G., Daum G. Association between the endoplasmic reticulum and mitochondria of yeast facilitates interorganelle transport of phospholipids through membrane contact. Eur J Biochem 1999, 264:545-553.
7. Holthuis J.C.M., Levine T.P. Lipid traffic: floppy drives and a superhighway. Nat Rev Mol Cell Biol 2005, 6:209-220.
8. Elbaz Y., Schuldiner M. Staying in touch: the molecular era of organelle contact sites. Trends Biochem Sci 2011, 36:616-623.
9. Kornmann B., Currie E., Collins S.R., Schuldiner M., Nunnari J., Weissman J.S., Walter P. An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science 2009, 325:477-481.
10. Kornmann B., Osman C., Walter P. The conserved GTPase Gem1 regulates endoplasmic reticulum-mitochondria connections. Proc Natl Acad Sci 2011, 108:14151-14156.
11. Lahiri S., Chao J.T., Tavassoli S., Wong A.K.O., Choudhary V., Young B.P., Loewen C.J.R., Prinz W.A. A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondria. PLoS Biol 2014, 12:e1001969.
12. Stefan C.J., Manford A.G., Baird D., Yamada-Hanff J., Mao Y., Emr S.D. Osh proteins regulate phosphoinositide metabolism at ER-plasma membrane contact sites. Cell 2011, 144:389-401.
13. Stefan C.J., Manford A.G., Emr S.D. PM connections: sites of information transfer and inter-organelle communication. Curr Opin Cell Biol 2013, 25:434-442.
14. Giordano F., Saheki Y., Idevall-Hagren O., Colombo S.F., Pirruccello M., Milosevic I., Gracheva E.O., Bagriantsev S.N., Borgese N., de Camilli P. PI(4,5)P(2)-dependent and Ca(2+)-regulated ER-PM interactions mediated by the extended synaptotagmins. Cell 2013, 153:1494-1509.
15. Schauder C.M., Wu X., Saheki Y., Narayanaswamy P., Torta F., Wenk M.R., Pietro De Camilli, Reinisch K.M. Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer. Nature 2014, 510:552-555.
16. Tafesse F.G., Vacaru A.M., Bosma E.F., Hermansson M., Jain A., Hilderink A., Somerharju P., Holthuis J.C.M. Sphingomyelin synthase-related protein SMSr is a suppressor of ceramide-induced mitochondrial apoptosis. J Cell Sci 2014, 127:445-454.
17. Pan X., Roberts P., Chen Y., Kvam E., Shulga N., Huang K., Lemmon S., Goldfarb D.S. Nucleus-vacuole junctions in Saccharomyces cerevisiae are formed through the direct interaction of Vac8p with Nvj1p. Mol Biol Cell 2000, 11:2445-2457.
18. Roberts P., Moshitch-Moshkovitz S., Kvam E., O'Toole E., Winey M., Goldfarb D.S. Piecemeal microautophagy of nucleus in Saccharomyces cerevisiae. Mol Biol Cell 2003, 14:129-141.
19. Kvam E., Goldfarb D.S. Structure and function of nucleus-vacuole junctions: outer-nuclear-membrane targeting of Nvj1p and a role in tryptophan uptake. J Cell Sci 2006, 119:3622-3633.
20. Loewen C.J.R., Roy A., Levine T.P. A conserved ER targeting motif in three families of lipid binding proteins and in Opi1p binds VAP. EMBO J 2003, 22:2025-2035.
21. Hönscher C., Ungermann C. A close-up view of membrane contact sites between the endoplasmic reticulum and the endolysosomal system: from yeast to man. Crit Rev Biochem Mol Biol 2014, 49:262-268.
22. de Saint-Jean M., Delfosse V., Douguet D., Chicanne G., Payrastre B., Bourguet W., Antonny B., Drin G. Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers. J Cell Biol 2011, 195:965-978.
23. Ling Y., Hayano S., Novick P. Osh4p is needed to reduce the level of phosphatidylinositol-4-phosphate on secretory vesicles as they mature. Mol Biol Cell 2014, 25:3389-3400.
24. Maeda K., Anand K., Chiapparino A., Kumar A., Poletto M., Kaksonen M., Gavin A.-C. Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins. Nature 2013, 501:257-261.
25. Hammond G.R.V., Machner M.P., Balla T. A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi. J Cell Biol 2014, 183:1061.
26. Elbaz-Alon Y., Rosenfeld-Gur E., Shinder V., Futerman A.H., Geiger T., Schuldiner M. A dynamic interface between vacuoles and mitochondria in yeast. Dev Cell 2014, 30:95-102.
27. Hönscher C., Mari M., Auffarth K., Bohnert M., Griffith J., Geerts W., van der Laan M., Cabrera M., Reggiori F., Ungermann C. Cellular metabolism regulates contact sites between vacuoles and mitochondria. Dev Cell 2014, 30:86-94.
28. Sato T., Darsow T., Emr S. Vam7p, a SNAP-25-like molecule, and Vam3p, a syntaxin homolog, function together in yeast vacuolar protein trafficking. Mol Cell Biol 1998, 18:5308-5319.
29. Ungermann C., Wickner W. Vam7p, a vacuolar SNAP-25 homolog, is required for SNARE complex integrity and vacuole docking and fusion. EMBO J 1998, 17:3269-3276.
30. Price A., Wickner W., Ungermann C. Proteins needed for vesicle budding from the golgi complex are also required for the docking step of homotypic vacuole fusion. J Cell Biol 2000, 148:1223-1230.
31. Seals D., Eitzen G., Margolis N., Wickner W., Price A. A Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion. Proc Natl Acad Sci U S A 2000, 97:9402-9407.
32. Bröcker C., Kuhlee A., Gatsogiannis C., Kleine Balderhaar H.J., Hönscher C., Engelbrecht-Vandré S., Ungermann C., Raunser S. Molecular architecture of the multisubunit homotypic fusion and vacuole protein sorting (HOPS) tethering complex. Proc Natl Acad Sci 2012, 109:1991-1996.
33. Binda M., Péli-Gulli M.-P., Bonfils G., Panchaud N., Urban J., Sturgill T.W., Loewith R., de Virgilio C. The Vam6 GEF controls TORC1 by activating the EGO complex. Mol Cell 2009, 35:563-573.
34. Merz S., Westermann B. Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. Genome Biol 2009, 10:R95.
35. Chen S., Tarsio M., Kane P.M., Greenberg M.L. Cardiolipin mediates cross-talk between mitochondria and the vacuole. Mol Biol Cell 2008, 19:5047-5058.
36. Nguyen T., Lewandowska A., Choi J.-Y., Markgraf D.F., Junker M., Bilgin M., Ejsing C.S., Voelker D.R., Rapoport T.A., Shaw J.M. Gem1 and ERMES do not directly affect phosphatidylserine transport from ER to mitochondria or mitochondrial inheritance. Traffic 2012, 13:880-890.
37. Suresh H.G., da Silveira Dos Santos A.X., Kukulski W., Tyedmers J., Riezman H., Bukau B., Mogk A. Prolonged starvation drives reversible sequestration of lipid biosynthetic enzymes and organelle reorganization in Saccharomyces cerevisiae. Mol Biol Cell 2015, 10.1091/mbc.E14-11-1559.
38. Bar-Peled L., Sabatini D.M. Regulation of mTORC1 by amino acids. Trends Cell Biol 2014, 24:400-406.
39. Dubouloz F., Deloche O., Wanke V., Cameroni E., de Virgilio C. The TOR and EGO protein complexes orchestrate microautophagy in yeast. Mol Cell 2005, 19:15-26.
40. de Brito O.M., Scorrano L. Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature 2008, 456:605-610.
41. Daniele T., Hurbain I., Vago R., Casari G., Raposo G., Tacchetti C., Schiaffino M.V. Mitochondria and melanosomes establish physical contacts modulated by Mfn2 and involved in organelle biogenesis. Curr Biol 2014, 24:393-403.
42. Sheftel A.D., Zhang A.-S., Brown C., Shirihai O.S., Ponka P. Direct interorganellar transfer of iron from endosome to mitochondrion. Blood 2007, 110:125-132.
43. Caplan S., Hartnell L., Aguilar R., Naslavsky N., Bonifacino J. Human Vam6p promotes lysosome clustering and fusion in vivo. J Cell Biol 2001, 154:109-122.
44. van der Laan M., Bohnert M., Wiedemann N., Pfanner N. Role of MINOS in mitochondrial membrane architecture and biogenesis. Trends Cell Biol 2012, 22:185-192.
45. Kornmann B., Walter P. ERMES-mediated ER-mitochondria contacts: molecular hubs for the regulation of mitochondrial biology. J Cell Sci 2010, 123:1389-1393.
46. Zick M., Wickner W.T. A distinct tethering step is vital for vacuole membrane fusion. eLife 2014, 3:e03251.
47. Peplowska K., Markgraf D.F., Ostrowicz C.W., Bange G., Ungermann C. The CORVET tethering complex interacts with the yeast Rab5 homolog Vps21 and is involved in endo-lysosomal biogenesis. Dev Cell 2007, 12:739-750.
48. Nickerson D.P., Brett C.L., Merz A.J. Vps-C complexes: gatekeepers of endolysosomal traffic. Curr Opin Cell Biol 2009, 21:543-551.
49. Auffarth K., Arlt H., Lachmann J., Cabrera M., Ungermann C. Tracking of the dynamic localization of the Rab-specific HOPS subunits reveal their distinct interaction with Ypt7 and vacuoles. Cell Logistics 2014, 4:e29191.
50. Lobingier B.T., Merz A.J. Sec1/Munc18 protein Vps33 binds to SNARE domains and the quaternary SNARE complex. Mol Biol Cell 2012, 23:4611-4622.
51. Kvam E., Goldfarb D.S. Nvj1p is the outer-nuclear-membrane receptor for oxysterol-binding protein homolog Osh1p in Saccharomyces cerevisiae. J Cell Sci 2004, 117:4959-4968.
52. Mesmin B., Bigay J., Filseck von J.M., Lacas-Gervais S., Drin G., Antonny B. A four-step cycle driven by PI(4)P hydrolysis directs sterol/PI(4)P exchange by the ER-Golgi tether OSBP. Cell 2013, 155:830-843.
53. Tavassoli S., Chao J.T., Young B.P., Cox R.C., Prinz W.A., de Kroon A.I.P.M., Loewen C.J.R. Plasma membrane-endoplasmic reticulum contact sites regulate phosphatidylcholine synthesis. EMBO Rep 2013, 14:434-440.
54. Manford A.G., Stefan C.J., Yuan H.L., MacGurn J.A., Emr S.D. ER-to-plasma membrane tethering proteins regulate cell signaling and ER morphology. Dev Cell 2012, 23:1129-1140.