Association between the endoplasmic reticulum and mitochondria of yeast facilitates interorganelle transport of phospholipids through membrane contact

European Journal of Biochemistry

Volumn 264, Issue 2, 1999, Pages 545-553

  Achleitner, G ^a   Gaigg, B ^a   Krasser, A ^a   Kainersdorfer, E ^a   Kohlwein, S D ^a   Perktold, A ^b   Zellnig, G ^b   Daum, G ^a  

^a GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^b Technische Universität Graz ^*

Author keywords

Endoplasmic reticulum; Membrane association; Mitochondria; Phospholipids; Saccharomyces cerevisiae

Indexed keywords

ADENOSINE TRIPHOSPHATE; CATION; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLSERINE; PHOSPHOLIPID; PROTEINASE K;

ARTICLE; CELL MEMBRANE; CELL ORGANELLE; DECARBOXYLATION; ELECTRON MICROSCOPY; ENDOPLASMIC RETICULUM; FLUORESCENCE MICROSCOPY; MITOCHONDRION; NONHUMAN; PHOSPHOLIPID TRANSFER; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; SACCHAROMYCES CEREVISIAE; YEAST;

BIOLOGICAL TRANSPORT; ENDOPEPTIDASE K; ENDOPLASMIC RETICULUM; IMAGE PROCESSING, COMPUTER-ASSISTED; INTRACELLULAR MEMBRANES; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLETHANOLAMINES; PHOSPHATIDYLSERINES; PHOSPHOLIPIDS; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE;

EID: 0033199506     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00658.x     Document Type: Article

References (42)

1. Voelker, D.R. (1991) Organelle biosynthesis and intracellular lipid transport in eukaryotes. Microbiol. Rev. 55, 543-560.
2. Moreau, P. & Cassagne, C. (1994) Phospholipid trafficking and membrane biogenesis. Biochim. Biophys. Acta 1197, 257-290.
3. Daum, G. & Vance, J.E. (1997) Import of lipids into mitochondria. Prog. Lipid Res. 36, 103-130.
4. Wirtz, K.W.A. (1991) Phospholipid transfer proteins. Annu, Rev. Biochem. 60, 73-99.
5. Wirtz, K.W.A. (1997) Phospholipid transfer proteins revisited. Biochem. J. 324, 353-360.
6. Kobayashi, T. & Pagano, R.E. (1989) Lipid transport during mitosis. J. Biol. Chem. 264, 5966-5973.
7. Puoti, A., Desponds, C. & Conzelmann, A. (1991) Biosynthesis of mannosylinositol-phosphoceramide in Saccharomyces cerevisiae is dependent on genes controlling the flow of secretory vesicles from the endoplasmic reticulum to the Golgi. J. Cell. Biol. 113, 515-525.
8. Hechtberger, P. & Daum, G. (1995) Intracellular transport of inositol-containing sphingolipids in the yeast, Saccharomyces cerevisiae. FEBS Lett. 367, 201-204.
9. Kaplan, M.R. & Simoni, R.D. (1985) Transport of cholesterol from the endoplasmic reticulum to the plasma membrane. J. Cell Biol. 101, 446-453.
10. Sleight, R.G. & Pagano, R.E. (1983) Rapid appearance of newly synthesized phosphatidylethanolamine at the plasma membrane. J. Biol. Chem. 258, 9050-9058.
11. Atkinson, K. (1983) Membrane function in yeast lipid synthesis mutants. In Biosynthesis and Function of Plant Lipids (Thomson, W.W., Madd, J.B. & Gibbs, M., eds) pp. 229-249. Waverly Press, Baltimore.
12. Vance, J.E. & Shiao, Y.J. (1996) Intracellular trafficking of phospholipids: Import of phosphatidylserine into mitochondria. Anticancer Res. 16, 1333-1340.
13. Voelker, D.R. (1989) Phosphatidylserine translocation to the mitochondrion is an ATP dependent process in permeabilized animal cells. Proc. Natl Acad. Sci. USA 86, 9921-9925.
14. Vance, J.E. (1991) Newly made phosphatidylserine and phosphatidylethanolamine are preferentially translocated between rat liver mitochondria and endoplasmic reticulum. J. Biol. Chem. 266, 89-97.
15. Achleitner, G., Zweytick, D., Trotter, P., Voelker, D. & Daum, G. (1995) Synthesis and intracellular transport of aminoglycerophospholipids in permeabilized cells of the yeast, Saccharomyces cerevisiae. J. Biol. Chem. 270, 29836-29842.
16. Voelker, D.R. (1993) The ATP-dependent translocation of phosphatidylserine to the mitochondria is a process that is restricted to the autologous organelle. J. Biol. Chem. 268, 7069-7074.
17. Vance, J.E. (1990) Phospholipid synthesis in a membrane fraction associated with mitochondria. J. Biol. Chem. 265, 7248-7256.
18. Ardail, D., Gasnier, F., Lerme, F., Simonot, C., Louisot, P. & Gateau-Roesch, O. (1993) Involvement of mitochondrial contact sites in the subcellular compartmentalization of phospholipid biosynthetic enzymes. J. Biol. Chem. 268, 25985-25992.
19. Camici, O. & Corazzi, L. (1995) Import of phosphatidylethanolamine for the assembly of rat brain mitochondrial membranes. J. Membr. Biol. 148, 169-176.
20. Shiao, Y.J., Lupo, G. & Vance, J.E. (1995) Evidence that phosphatidylserine is imported into mitochondria via a mitochondria-associated membrane and that the majority of mitochondrial phosphatidylethanolamine is derived from decarboxylation of phosphatidylserine. J. Biol. Chem. 270, 11190-11198.
21. Gaigg, B., Simbeni, R., Hrastnik, C., Paltauf, F. & Daum, G. (1995) Characterization of a microsomal subfraction associated with mitochondria of the yeast, Saccharomyces cerevisiae. Biochim. Biophys. Acta 1234, 214-220.
22. Cui, Z., Vance, J.E., Chen, M.H., Voelker, D.R. & Vance, D.E. (1993) Cloning and expression of a novel phosphatidylethanolamine N-methyltransferase. J. Biol. Chem. 268, 16655-16663.
23. Yamashita, S. & Nikawa, J.-I. (1997) Phosphatidylserine synthase from yeast. Biochim. Biophys. Acta 1348, 228-235.
24. Trotter, P.J. & Voelker, D.R. (1995) Identification of a non-mitochondrial phosphatidylserine decarboxylase activity (PSD2) in the yeast Saccharomyces cerevisiae. J. Biol. Chem. 270, 6062-6070.
25. Kanipes, M.I. & Henry, S.A. (1997). The phospholipid methyltransferases in yeast. Biochim. Biophys. Acta 1348, 134-141.
26. Sperka-Gottlieb, C.D.M., Fasch, E.-V., Kuchler, K., Bailis, A.M., Henry, S.A., Paltauf, F. & Kohlwein, S.D. (1990) The hydrophilic and acidic N-terminus of the integral membrane enzyme phosphatidylserine synthase is required for efficient membrane insertion. Yeast 6, 331-343.
27. 2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondria. J. Biol. Chem. 257, 13028-13033.
28. Hirsch, P.J. & Henry, S.A. (1986) Expression of the Saccharomyces cerevisiae inositol-1-phosphate synthase (INOI) gene is regulated by factors that affect phospholipid synthesis. Mol. Cell. Biol. 6, 3320-3328.
29. Stevens, B.J. (1977) Variation in number and volume of the mitochondria in yeast according to growth conditions. A study based on serial sectioning and computer graphics reconstruction. Biol. Cell. 29, 37-56.
30. Bailis, A.M., Lopes, J.M., Kohlwein, S.D, & Henry, S.A. (1992) Cis and trans regulatory elements required for regulation of the CHO1 gene of Saccharomyces cerevisiae. Nucleic Acids Res. 20, 1411-1418.
31. Maniatis, T., Fritsch, E.F. & Sambrook, J, (1982) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
32. Ito, H., Fukuda, Y., Murata, K. & Kimura, A. (1983) Transformation of intact yeast cells treated with alkali cations. J. Bacteriol. 153, 163-168.
33. Folch, J., Lees, M. & Sloane-Stanley, G.H. (1957) A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226, 497-509.
34. Zinser, E., Sperka-Gottlieb, C.D.M., Fasch, E.-V., Kohlwein, S.D., Paltauf, F. & Daum, G. (1991). Phospholipid synthesis and lipid composition of subcellular membranes in the unicellular eucaryote Saccharomyces cerevisiae. J. Bacteriol. 173, 2026-2034.
35. Titorenko, V.I. & Rachubinski, R.A. (1998) The endoplasmic reticulum plays an essential role in peroxisome biogenesis. Trends Biochem. Sci. 23, 231-233.
36. Titorenko, V.I. & Rachubinski, R.A. (1998) Mutants of the yeast Yarrowia lipolytica defective in protein exit from the endoplasmic reticulum are also defective in peroxisome biogenesis. Mol. Cell. Biol. 18, 2789-2803.
37. Elgersma, Y., Kwast, L., van den Berg, M., Snyder, W.B., Distel, B., Subramani, S. & Tabak, H.F. (1997) Overexpression of Pex15p, a phosphorylated peroxisomal integral membrane protein required for peroxisome assembly in S. cerevisiae causes proliferation of the endoplasmic reticulum membrane. EMBO J. 16, 7326-7341.
38. Simbeni, R., Paltauf, F. & Daum, G. (1990) Intramitochondrial transfer of phospholipids in the yeast, Saccharomyces cerevisiae. J. Biol. Chem. 265, 281-285.
39. Shiao, Y.J., Balcerzak, B. & Vance, J.E. (1998) A mitochondrial membrane protein is required for translocation of phosphatidylserine from mitochondria-associated membranes to mitochondria. Biochem. J. 331, 217-223.
40. Camici, O. & Corazzi, L. (1997) Phosphatidylserine translocation into brain mitochondria: involvement of a fusogenic protein associated with mitochondrial membranes. Mol. Cell Biochem. 175, 71-80.
41. Rakowska, M., Zborowski, J. & Corazzi, L. (1994) A fusogenic protein from rat microsomal membranes: partial purification and reconstitution into liposomes. Membr. Biol. 142, 35-42.
42. Heikinheimo, L. & Somerharju, P. (1998) Preferential decarboxylation of hydrophilic phosphatidylserine species in cultured cells. Implications on the mechanism of transport to mitochondria and cellular aminophospholipid species compositions. J. Biol. Chem. 273, 3327-3335.