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Volumn 6, Issue FEB, 2015, Pages

xCT, not just an amino-acid transporter: A multi-functional regulator of microbial infection and associated diseases

Author keywords

Bacteria; Cysteine; Glutamate; KSHV; Virus; XCT

Indexed keywords

AMINO ACID TRANSPORTER; BETA INTEGRIN; CD147 ANTIGEN; CD98 ANTIGEN; CISPLATIN; CYSTINE; DOXORUBICIN; GLUTAMIC ACID; GLUTATHIONE; HERPESVIRUS ENTRY MEDIATOR; LATENCY ASSOCIATED NUCLEAR ANTIGEN; MESSENGER RNA; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 1; SALAZOSULFAPYRIDINE;

EID: 84927557321     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2015.00120     Document Type: Short Survey
Times cited : (18)

References (68)
  • 1
    • 0038082194 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) infection of human fibroblast cells occurs through endocytosis
    • Akula, S. M., Naranatt, P. P., Walia, N. S., Wang, F. Z., Fegley, B., and Chandran, B. (2003). Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) infection of human fibroblast cells occurs through endocytosis. J. Virol. 77, 7978-7990. doi: 10.1128/JVI.77.14.7978-7990.2003.
    • (2003) J. Virol , vol.77 , pp. 7978-7990
    • Akula, S.M.1    Naranatt, P.P.2    Walia, N.S.3    Wang, F.Z.4    Fegley, B.5    Chandran, B.6
  • 2
    • 0022969399 scopus 로고
    • Exchange of cystine and glutamate across plasma membrane of human fibroblasts
    • Bannai, S. (1986). Exchange of cystine and glutamate across plasma membrane of human fibroblasts. J. Biol. Chem. 261, 2256-2263.
    • (1986) J. Biol. Chem , vol.261 , pp. 2256-2263
    • Bannai, S.1
  • 3
    • 0018963749 scopus 로고
    • Transport interaction of L-cystine and L-glutamate in human diploid fibroblasts in culture
    • Bannai, S., and Kitamura, E. (1980). Transport interaction of L-cystine and L-glutamate in human diploid fibroblasts in culture. J. Biol. Chem. 255, 2372-2376.
    • (1980) J. Biol. Chem , vol.255 , pp. 2372-2376
    • Bannai, S.1    Kitamura, E.2
  • 4
    • 4344601384 scopus 로고    scopus 로고
    • Induction of cystine-glutamate transporter xc-by human immunodeficiency virus type 1 transactivator protein tat in retinal pigment epithelium
    • Bridges, C. C., Hu, H., Miyauchi, S., Siddaramappa, U. N., Ganapathy, M. E., Ignatowicz, L., et al. (2004). Induction of cystine-glutamate transporter xc-by human immunodeficiency virus type 1 transactivator protein tat in retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 45, 2906-2914. doi: 10.1167/iovs.03-1355.
    • (2004) Invest. Ophthalmol. Vis. Sci , vol.45 , pp. 2906-2914
    • Bridges, C.C.1    Hu, H.2    Miyauchi, S.3    Siddaramappa, U.N.4    Ganapathy, M.E.5    Ignatowicz, L.6
  • 5
    • 84867812018 scopus 로고    scopus 로고
    • Current status of HIV infection and ocular disease
    • Butler, N. J., and Thorne, J. E. (2012). Current status of HIV infection and ocular disease. Curr. Opin. Ophthalmol. 23, 517-522. doi: 10.1097/ICU.0b013e328358ba85.
    • (2012) Curr. Opin. Ophthalmol , vol.23 , pp. 517-522
    • Butler, N.J.1    Thorne, J.E.2
  • 6
    • 0029069445 scopus 로고
    • Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas
    • Cesarman, E., Chang, Y., Moore, P. S., Said, J. W., and Knowles, D. M. (1995). Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. N. Engl. J. Med. 332, 1186-1191. doi: 10.1056/NEJM199505043321802.
    • (1995) N. Engl. J. Med , vol.332 , pp. 1186-1191
    • Cesarman, E.1    Chang, Y.2    Moore, P.S.3    Said, J.W.4    Knowles, D.M.5
  • 7
    • 0028588064 scopus 로고
    • Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma
    • Chang, Y., Cesarman, E., Pessin, M. S., Lee, F., Culpepper, J., Knowles, D. M., et al. (1994). Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 266, 1865-1869. doi: 10.1126/science.7997879.
    • (1994) Science , vol.266 , pp. 1865-1869
    • Chang, Y.1    Cesarman, E.2    Pessin, M.S.3    Lee, F.4    Culpepper, J.5    Knowles, D.M.6
  • 8
    • 35548981667 scopus 로고    scopus 로고
    • Primary effusion lymphoma
    • Chen, Y. B., Rahemtullah, A., and Hochberg, E. (2007). Primary effusion lymphoma. Oncologist 12, 569-576. doi: 10.1634/theoncologist.12-5-569.
    • (2007) Oncologist , vol.12 , pp. 569-576
    • Chen, Y.B.1    Rahemtullah, A.2    Hochberg, E.3
  • 9
    • 0023137252 scopus 로고
    • Ionic dependence of glutamate neurotoxicity
    • Choi, D. W. (1987). Ionic dependence of glutamate neurotoxicity. J. Neurosci. 7, 369-379.
    • (1987) J. Neurosci , vol.7 , pp. 369-379
    • Choi, D.W.1
  • 10
    • 23444449591 scopus 로고    scopus 로고
    • Inhibition of cystine uptake disrupts the growth of primary brain tumors
    • Chung, W. J., Lyons, S. A., Nelson, G. M., Hamza, H., Gladson, C. L., Gillespie, G. Y., et al. (2005). Inhibition of cystine uptake disrupts the growth of primary brain tumors. J. Neurosci. 25, 7101-7110. doi: 10.1523/JNEUROSCI.5258-04.2005.
    • (2005) J. Neurosci , vol.25 , pp. 7101-7110
    • Chung, W.J.1    Lyons, S.A.2    Nelson, G.M.3    Hamza, H.4    Gladson, C.L.5    Gillespie, G.Y.6
  • 11
    • 84898543118 scopus 로고    scopus 로고
    • Targeting xCT, a cystine-glutamate transporter induces apoptosis and tumor regression for KSHV/HIV-associated lymphoma
    • Dai, L., Cao, Y., Chen, Y., Parsons, C., and Qin, Z. (2014a). Targeting xCT, a cystine-glutamate transporter induces apoptosis and tumor regression for KSHV/HIV-associated lymphoma. J. Hematol. Oncol. 7, 30. doi: 10.1186/1756-8722-7-30.
    • (2014) J. Hematol. Oncol , vol.7 , pp. 30
    • Dai, L.1    Cao, Y.2    Chen, Y.3    Parsons, C.4    Qin, Z.5
  • 12
    • 84903397341 scopus 로고    scopus 로고
    • Lipoteichoic acid (LTA) and lipopolysaccharides (LPS) from periodontal pathogenic bacteria facilitate oncogenic herpesvirus infection within primary oral cells
    • Dai, L., Defee, M. R., Cao, Y., Wen, J., Wen, X., Noverr, M. C., et al. (2014b). Lipoteichoic acid (LTA) and lipopolysaccharides (LPS) from periodontal pathogenic bacteria facilitate oncogenic herpesvirus infection within primary oral cells. PLoS ONE 9:e101326. doi: 10.1371/journal.pone.0101326.
    • (2014) PLoS ONE , vol.9
    • Dai, L.1    Defee, M.R.2    Cao, Y.3    Wen, J.4    Wen, X.5    Noverr, M.C.6
  • 13
    • 84896537900 scopus 로고    scopus 로고
    • Systematic analysis of a xenograft mice model for KSHV+ primary effusion lymphoma (PEL)
    • Dai, L., Trillo-Tinoco, J., Bai, L., Kang, B., Xu, Z., Wen, X., et al. (2014c). Systematic analysis of a xenograft mice model for KSHV+ primary effusion lymphoma (PEL). PLoS ONE 9:e90349. doi: 10.1371/journal.pone.0090349.
    • (2014) PLoS ONE , vol.9
    • Dai, L.1    Trillo-Tinoco, J.2    Bai, L.3    Kang, B.4    Xu, Z.5    Wen, X.6
  • 14
    • 84858151605 scopus 로고    scopus 로고
    • Kaposi sarcoma-associated herpesvirus (KSHV) induces a functional tumor-associated phenotype for oral fibroblasts
    • Dai, L., Qin, Z., Defee, M., Toole, B. P., Kirkwood, K. L., and Parsons, C. (2012). Kaposi sarcoma-associated herpesvirus (KSHV) induces a functional tumor-associated phenotype for oral fibroblasts. Cancer Lett. 318, 214-220. doi: 10.1016/j.canlet.2011.12.019.
    • (2012) Cancer Lett , vol.318 , pp. 214-220
    • Dai, L.1    Qin, Z.2    Defee, M.3    Toole, B.P.4    Kirkwood, K.L.5    Parsons, C.6
  • 15
    • 84861648384 scopus 로고    scopus 로고
    • Global burden of cancers attributable to infections in 2008, a review and synthetic analysis
    • de Martel, C., Ferlay, J., Franceschi, S., Vignat, J., Bray, F., Forman, D., et al. (2012). Global burden of cancers attributable to infections in 2008: a review and synthetic analysis. Lancet Oncol. 13, 607-615. doi: 10.1016/S1470-2045(12)70137-7.
    • (2012) Lancet Oncol , vol.13 , pp. 607-615
    • de Martel, C.1    Ferlay, J.2    Franceschi, S.3    Vignat, J.4    Bray, F.5    Forman, D.6
  • 16
    • 0036682922 scopus 로고    scopus 로고
    • Characterization of Kaposi sarcoma-associated herpesvirus/human herpesvirus-8 infection of human vascular endothelial cells: early events
    • Dezube, B. J., Zambela, M., Sage, D. R., Wang, J. F., and Fingeroth, J. D. (2002). Characterization of Kaposi sarcoma-associated herpesvirus/human herpesvirus-8 infection of human vascular endothelial cells: early events. Blood 100, 888-896. doi: 10.1182/blood.V100.3.888.
    • (2002) Blood , vol.100 , pp. 888-896
    • Dezube, B.J.1    Zambela, M.2    Sage, D.R.3    Wang, J.F.4    Fingeroth, J.D.5
  • 17
    • 84892463414 scopus 로고    scopus 로고
    • Efficient infection of a human B cell line with cell-free Kaposi's sarcoma-associated herpesvirus
    • Dollery, S. J., Santiago-Crespo, R. J., Kardava, L., Moir, S., and Berger, E. A. (2014). Efficient infection of a human B cell line with cell-free Kaposi's sarcoma-associated herpesvirus. J. Virol. 88, 1748-1757. doi: 10.1128/JVI.03063-13.
    • (2014) J. Virol , vol.88 , pp. 1748-1757
    • Dollery, S.J.1    Santiago-Crespo, R.J.2    Kardava, L.3    Moir, S.4    Berger, E.A.5
  • 18
    • 33846628923 scopus 로고    scopus 로고
    • Sulfasalazine-induced cystine starvation: potential use for prostate cancer therapy
    • Doxsee, D. W., Gout, P. W., Kurita, T., Lo, M., Buckley, A. R., Wang, Y., et al. (2007). Sulfasalazine-induced cystine starvation: potential use for prostate cancer therapy. Prostate 67, 162-171. doi: 10.1002/pros.20508.
    • (2007) Prostate , vol.67 , pp. 162-171
    • Doxsee, D.W.1    Gout, P.W.2    Kurita, T.3    Lo, M.4    Buckley, A.R.5    Wang, Y.6
  • 19
    • 20044364737 scopus 로고    scopus 로고
    • Clinical role of multidrug resistance protein 1 expression in chemotherapy resistance in early-stage breast cancer: the Austrian Breast and Colorectal Cancer Study Group
    • Filipits, M., Pohl, G., Rudas, M., Dietze, O., Lax, S., Grill, R., et al. (2005). Clinical role of multidrug resistance protein 1 expression in chemotherapy resistance in early-stage breast cancer: the Austrian Breast and Colorectal Cancer Study Group. J. Clin. Oncol. 23, 1161-1168. doi: 10.1200/JCO.2005.03.033.
    • (2005) J. Clin. Oncol , vol.23 , pp. 1161-1168
    • Filipits, M.1    Pohl, G.2    Rudas, M.3    Dietze, O.4    Lax, S.5    Grill, R.6
  • 20
    • 79955411065 scopus 로고    scopus 로고
    • Helminths in human carcinogenesis
    • Fried, B., Reddy, A., and Mayer, D. (2011). Helminths in human carcinogenesis. Cancer Lett. 305, 239-249. doi: 10.1016/j.canlet.2010.07.008.
    • (2011) Cancer Lett , vol.305 , pp. 239-249
    • Fried, B.1    Reddy, A.2    Mayer, D.3
  • 21
    • 84904869497 scopus 로고    scopus 로고
    • KSHV attachment and entry are dependent on αVβ3 integrin localized to specific cell surface microdomains and do not correlate with the presence of heparan sulfate
    • Garrigues, H. J., Demaster, L. K., Rubinchikova, Y. E., and Rose, T. M. (2014). KSHV attachment and entry are dependent on αVβ3 integrin localized to specific cell surface microdomains and do not correlate with the presence of heparan sulfate. Virology 464-465, 118-133. doi: 10.1016/j.virol.2014.06.035.
    • (2014) Virology , vol.464-465 , pp. 118-133
    • Garrigues, H.J.1    Demaster, L.K.2    Rubinchikova, Y.E.3    Rose, T.M.4
  • 22
    • 0034772516 scopus 로고    scopus 로고
    • Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the xc-cystine transporter: a new action for an old drug
    • Gout, P. W., Buckley, A. R., Simms, C. R., and Bruchovsky, N. (2001). Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the xc-cystine transporter: a new action for an old drug. Leukemia 15, 1633-1640. doi: 10.1038/sj.leu.2402238.
    • (2001) Leukemia , vol.15 , pp. 1633-1640
    • Gout, P.W.1    Buckley, A.R.2    Simms, C.R.3    Bruchovsky, N.4
  • 23
    • 70049116403 scopus 로고    scopus 로고
    • Actin dynamics regulate multiple endosomal steps during Kaposi's sarcoma-associated herpesvirus entry and trafficking in endothelial cells
    • Greene, W., and Gao, S. J. (2009). Actin dynamics regulate multiple endosomal steps during Kaposi's sarcoma-associated herpesvirus entry and trafficking in endothelial cells. PLoS Pathog. 5:e1000512. doi: 10.1371/journal.ppat.1000512.
    • (2009) PLoS Pathog , vol.5
    • Greene, W.1    Gao, S.J.2
  • 24
    • 80053304909 scopus 로고    scopus 로고
    • Disruption of xCT inhibits cell growth via the ROS/autophagy pathway in hepatocellular carcinoma
    • Guo, W., Zhao, Y., Zhang, Z., Tan, N., Zhao, F., Ge, C., et al. (2011). Disruption of xCT inhibits cell growth via the ROS/autophagy pathway in hepatocellular carcinoma. Cancer Lett. 312, 55-61. doi: 10.1016/j.canlet.2011.07.024.
    • (2011) Cancer Lett , vol.312 , pp. 55-61
    • Guo, W.1    Zhao, Y.2    Zhang, Z.3    Tan, N.4    Zhao, F.5    Ge, C.6
  • 25
    • 77957884283 scopus 로고    scopus 로고
    • HIV-Tat elicits microglial glutamate release: role of NAPDH oxidase and the cystine-glutamate antiporter
    • Gupta, S., Knight, A. G., Gupta, S., Knapp, P. E., Hauser, K. F., Keller, J. N., et al. (2010). HIV-Tat elicits microglial glutamate release: role of NAPDH oxidase and the cystine-glutamate antiporter. Neurosci. Lett. 485, 233-236. doi: 10.1016/j.neulet.2010.09.019.
    • (2010) Neurosci. Lett , vol.485 , pp. 233-236
    • Gupta, S.1    Knight, A.G.2    Gupta, S.3    Knapp, P.E.4    Hauser, K.F.5    Keller, J.N.6
  • 26
    • 58149382621 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus gH/gL: glycoprotein export and interaction with cellular receptors
    • Hahn, A., Birkmann, A., Wies, E., Dorer, D., Mahr, K., Sturzl, M., et al. (2009). Kaposi's sarcoma-associated herpesvirus gH/gL: glycoprotein export and interaction with cellular receptors. J. Virol. 83, 396-407. doi: 10.1128/JVI.01170-08.
    • (2009) J. Virol , vol.83 , pp. 396-407
    • Hahn, A.1    Birkmann, A.2    Wies, E.3    Dorer, D.4    Mahr, K.5    Sturzl, M.6
  • 27
    • 0036828695 scopus 로고    scopus 로고
    • Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity
    • Haimeur, A., Deeley, R. G., and Cole, S. P. (2002). Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity. J. Biol. Chem. 277, 41326-41333. doi: 10.1074/jbc.M206228200.
    • (2002) J. Biol. Chem , vol.277 , pp. 41326-41333
    • Haimeur, A.1    Deeley, R.G.2    Cole, S.P.3
  • 28
    • 79551515521 scopus 로고    scopus 로고
    • KSHV infects a subset of human tonsillar B cells, driving proliferation and plasmablast differentiation
    • Hassman, L. M., Ellison, T. J., and Kedes, D. H. (2011). KSHV infects a subset of human tonsillar B cells, driving proliferation and plasmablast differentiation. J. Clin. Invest. 121, 752-768. doi: 10.1172/JCI44185.
    • (2011) J. Clin. Invest , vol.121 , pp. 752-768
    • Hassman, L.M.1    Ellison, T.J.2    Kedes, D.H.3
  • 29
    • 23844486685 scopus 로고    scopus 로고
    • Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance
    • Huang, Y., Dai, Z., Barbacioru, C., and Sadee, W. (2005). Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance. Cancer Res. 65, 7446-7454. doi: 10.1158/0008-5472.CAN-04-4267.
    • (2005) Cancer Res , vol.65 , pp. 7446-7454
    • Huang, Y.1    Dai, Z.2    Barbacioru, C.3    Sadee, W.4
  • 30
    • 33748957350 scopus 로고    scopus 로고
    • Broad target cell selectivity of Kaposi's sarcoma-associated herpesvirus glycoprotein-mediated cell fusion and virion entry
    • Kaleeba, J. A., and Berger, E. A. (2006a). Broad target cell selectivity of Kaposi's sarcoma-associated herpesvirus glycoprotein-mediated cell fusion and virion entry. Virology 354, 7-14. doi: 10.1016/j.virol.2006.06.009.
    • (2006) Virology , vol.354 , pp. 7-14
    • Kaleeba, J.A.1    Berger, E.A.2
  • 31
    • 33645468403 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus fusion-entry receptor: cystine transporter xCT
    • Kaleeba, J. A., and Berger, E. A. (2006b). Kaposi's sarcoma-associated herpesvirus fusion-entry receptor: cystine transporter xCT. Science 311, 1921-1924. doi: 10.1126/science.1120878.
    • (2006) Science , vol.311 , pp. 1921-1924
    • Kaleeba, J.A.1    Berger, E.A.2
  • 32
    • 42949126711 scopus 로고    scopus 로고
    • The x(c)-cystine/glutamate antiporter: a potential target for therapy of cancer and other diseases
    • Lo, M., Wang, Y. Z., and Gout, P. W. (2008). The x(c)-cystine/glutamate antiporter: a potential target for therapy of cancer and other diseases. J. Cell. Physiol. 215, 593-602. doi: 10.1002/jcp.21366.
    • (2008) J. Cell. Physiol , vol.215 , pp. 593-602
    • Lo, M.1    Wang, Y.Z.2    Gout, P.W.3
  • 33
    • 79960736994 scopus 로고    scopus 로고
    • 'Introduction to the human gamma-herpesviruses'
    • eds A. Arvin, G. Campadelli-Fiume, E. Mocarski, P. S. Moore, B. Roizman, R. Whitley, and K. Yamanishi (Cambridge: Cambridge University Press)
    • Longnecker, R., and Neipel, F. (2007). "Introduction to the human gamma-herpesviruses, " in Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis, eds A. Arvin, G. Campadelli-Fiume, E. Mocarski, P. S. Moore, B. Roizman, R. Whitley, and K. Yamanishi (Cambridge: Cambridge University Press).
    • (2007) Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis
    • Longnecker, R.1    Neipel, F.2
  • 35
    • 66649121354 scopus 로고    scopus 로고
    • Antitumorigenesis of antioxidants in a transgenic Rac1 model of Kaposi's sarcoma
    • Ma, Q., Cavallin, L. E., Yan, B., Zhu, S., Duran, E. M., Wang, H., et al. (2009). Antitumorigenesis of antioxidants in a transgenic Rac1 model of Kaposi's sarcoma. Proc. Natl. Acad. Sci. U.S.A. 106, 8683-8688. doi: 10.1073/pnas.0812688106.
    • (2009) Proc. Natl. Acad. Sci. U.S.A , vol.106 , pp. 8683-8688
    • Ma, Q.1    Cavallin, L.E.2    Yan, B.3    Zhu, S.4    Duran, E.M.5    Wang, H.6
  • 36
    • 16544378834 scopus 로고    scopus 로고
    • Implications for oxidative and nitrative stress in the pathogenesis of AIDS-related Kaposi's sarcoma
    • Mallery, S. R., Pei, P., Landwehr, D. J., Clark, C. M., Bradburn, J. E., Ness, G. M., et al. (2004). Implications for oxidative and nitrative stress in the pathogenesis of AIDS-related Kaposi's sarcoma. Carcinogenesis 25, 597-603. doi: 10.1093/carcin/bgh042.
    • (2004) Carcinogenesis , vol.25 , pp. 597-603
    • Mallery, S.R.1    Pei, P.2    Landwehr, D.J.3    Clark, C.M.4    Bradburn, J.E.5    Ness, G.M.6
  • 38
    • 84896088630 scopus 로고    scopus 로고
    • Human viral oncogenesis: a cancer hallmarks analysis
    • Mesri, E. A., Feitelson, M. A., and Munger, K. (2014). Human viral oncogenesis: a cancer hallmarks analysis. Cell Host Microbe 15, 266-282. doi: 10.1016/j.chom.2014.02.011.
    • (2014) Cell Host Microbe , vol.15 , pp. 266-282
    • Mesri, E.A.1    Feitelson, M.A.2    Munger, K.3
  • 39
    • 79953104368 scopus 로고    scopus 로고
    • Infection of primary human tonsillar lymphoid cells by KSHV reveals frequent but abortive infection of T cells
    • Myoung, J., and Ganem, D. (2011). Infection of primary human tonsillar lymphoid cells by KSHV reveals frequent but abortive infection of T cells. Virology 413, 1-11. doi: 10.1016/j.virol.2010.12.036.
    • (2011) Virology , vol.413 , pp. 1-11
    • Myoung, J.1    Ganem, D.2
  • 41
    • 10444231111 scopus 로고    scopus 로고
    • Transport mechanism for aluminum citrate at the blood-brain barrier: kinetic evidence implies involvement of system Xc-in immortalized rat brain endothelial cells
    • Nagasawa, K., Ito, S., Kakuda, T., Nagai, K., Tamai, I., Tsuji, A., et al. (2005). Transport mechanism for aluminum citrate at the blood-brain barrier: kinetic evidence implies involvement of system Xc-in immortalized rat brain endothelial cells. Toxicol. Lett. 155, 289-296. doi: 10.1016/j.toxlet.2004.10.004.
    • (2005) Toxicol. Lett , vol.155 , pp. 289-296
    • Nagasawa, K.1    Ito, S.2    Kakuda, T.3    Nagai, K.4    Tamai, I.5    Tsuji, A.6
  • 42
    • 0842311704 scopus 로고    scopus 로고
    • Suppression of cystine uptake by sulfasalazine inhibits proliferation of human mammary carcinoma cells
    • Narang, V. S., Pauletti, G. M., Gout, P. W., Buckley, D. J., and Buckley, A. R. (2003). Suppression of cystine uptake by sulfasalazine inhibits proliferation of human mammary carcinoma cells. Anticancer. Res. 23, 4571-4579.
    • (2003) Anticancer. Res , vol.23 , pp. 4571-4579
    • Narang, V.S.1    Pauletti, G.M.2    Gout, P.W.3    Buckley, D.J.4    Buckley, A.R.5
  • 43
    • 0242499988 scopus 로고    scopus 로고
    • Role of cystine transport in intracellular glutathione level and cisplatin resistance in human ovarian cancer cell lines
    • Okuno, S., Sato, H., Kuriyama-Matsumura, K., Tamba, M., Wang, H., Sohda, S., et al. (2003). Role of cystine transport in intracellular glutathione level and cisplatin resistance in human ovarian cancer cell lines. Br. J. Cancer 88, 951-956. doi: 10.1038/sj.bjc.6600786.
    • (2003) Br. J. Cancer , vol.88 , pp. 951-956
    • Okuno, S.1    Sato, H.2    Kuriyama-Matsumura, K.3    Tamba, M.4    Wang, H.5    Sohda, S.6
  • 44
    • 84888290537 scopus 로고    scopus 로고
    • Lung cancer in never smokers: disease characteristics and risk factors
    • Pallis, A. G., and Syrigos, K. N. (2013). Lung cancer in never smokers: disease characteristics and risk factors. Crit. Rev. Oncol. Hematol. 88, 494-503. doi: 10.1016/j.critrevonc.2013.06.011.
    • (2013) Crit. Rev. Oncol. Hematol , vol.88 , pp. 494-503
    • Pallis, A.G.1    Syrigos, K.N.2
  • 45
    • 84878806545 scopus 로고    scopus 로고
    • Regional variations of antioxidant capacity and oxidative stress responses in HIV-1 transgenic rats with and without methamphetamine administration
    • Pang, X., Panee, J., Liu, X., Berry, M. J., Chang, S. L., and Chang, L. (2013). Regional variations of antioxidant capacity and oxidative stress responses in HIV-1 transgenic rats with and without methamphetamine administration. J. Neuroimmune Pharmacol. 8, 691-704. doi: 10.1007/s11481-013-9454-8.
    • (2013) J. Neuroimmune Pharmacol , vol.8 , pp. 691-704
    • Pang, X.1    Panee, J.2    Liu, X.3    Berry, M.J.4    Chang, S.L.5    Chang, L.6
  • 46
    • 84912117511 scopus 로고    scopus 로고
    • Prevention strategies for gastric cancer: a global perspective
    • Park, J. Y., Von Karsa, L., and Herrero, R. (2014). Prevention strategies for gastric cancer: a global perspective. Clin. Endosc. 47, 478-489. doi: 10.5946/ce.2014.47.6.478.
    • (2014) Clin. Endosc , vol.47 , pp. 478-489
    • Park, J.Y.1    Von Karsa, L.2    Herrero, R.3
  • 47
    • 0347480436 scopus 로고    scopus 로고
    • Differentiation of substrate and non-substrate inhibitors of transport system xc-: an obligate exchanger of L-glutamate and L-cystine
    • Patel, S. A., Warren, B. A., Rhoderick, J. F., and Bridges, R. J. (2004). Differentiation of substrate and non-substrate inhibitors of transport system xc-: an obligate exchanger of L-glutamate and L-cystine. Neuropharmacology 46, 273-284. doi: 10.1016/j.neuropharm.2003.08.006.
    • (2004) Neuropharmacology , vol.46 , pp. 273-284
    • Patel, S.A.1    Warren, B.A.2    Rhoderick, J.F.3    Bridges, R.J.4
  • 48
    • 0036226223 scopus 로고    scopus 로고
    • Human herpesvirus 8 glycoprotein B (gB), gH, and gL can mediate cell fusion
    • Pertel, P. E. (2002). Human herpesvirus 8 glycoprotein B (gB), gH, and gL can mediate cell fusion. J. Virol. 76, 4390-4400. doi: 10.1128/JVI.76.9.4390-4400.2002.
    • (2002) J. Virol , vol.76 , pp. 4390-4400
    • Pertel, P.E.1
  • 49
    • 33645217828 scopus 로고    scopus 로고
    • System Xc-and apolipoprotein E expressed by microglia have opposite effects on the neurotoxicity of amyloid-β peptide 1-40
    • Qin, S., Colin, C., Hinners, I., Gervais, A., Cheret, C., and Mallat, M. (2006). System Xc-and apolipoprotein E expressed by microglia have opposite effects on the neurotoxicity of amyloid-β peptide 1-40. J. Neurosci. 26, 3345-3356. doi: 10.1523/JNEUROSCI.5186-05.2006.
    • (2006) J. Neurosci , vol.26 , pp. 3345-3356
    • Qin, S.1    Colin, C.2    Hinners, I.3    Gervais, A.4    Cheret, C.5    Mallat, M.6
  • 50
    • 80054050786 scopus 로고    scopus 로고
    • Cooperative roles for emmprin and LYVE-1 in the regulation of chemoresistance for primary effusion lymphoma
    • Qin, Z., Dai, L., Bratoeva, M., Slomiany, M. G., Toole, B. P., and Parsons, C. (2011). Cooperative roles for emmprin and LYVE-1 in the regulation of chemoresistance for primary effusion lymphoma. Leukemia 25, 1598-1609. doi: 10.1038/leu.2011.144.
    • (2011) Leukemia , vol.25 , pp. 1598-1609
    • Qin, Z.1    Dai, L.2    Bratoeva, M.3    Slomiany, M.G.4    Toole, B.P.5    Parsons, C.6
  • 51
    • 84871970037 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus suppression of DUSP1 facilitates cellular pathogenesis following de novo infection
    • Qin, Z., Dai, L., Defee, M., Findlay, V. J., Watson, D. K., Toole, B. P., et al. (2013). Kaposi's sarcoma-associated herpesvirus suppression of DUSP1 facilitates cellular pathogenesis following de novo infection. J. Virol. 87, 621-635. doi: 10.1128/JVI.01441-12.
    • (2013) J. Virol , vol.87 , pp. 621-635
    • Qin, Z.1    Dai, L.2    Defee, M.3    Findlay, V.J.4    Watson, D.K.5    Toole, B.P.6
  • 52
    • 77952858493 scopus 로고    scopus 로고
    • Direct activation of emmprin and associated pathogenesis by an oncogenic herpesvirus
    • Qin, Z., Dai, L., Slomiany, M. G., Toole, B. P., and Parsons, C. (2010a). Direct activation of emmprin and associated pathogenesis by an oncogenic herpesvirus. Cancer Res. 70, 3884-3889. doi: 10.1158/0008-5472.CAN-09-4663.
    • (2010) Cancer Res , vol.70 , pp. 3884-3889
    • Qin, Z.1    Dai, L.2    Slomiany, M.G.3    Toole, B.P.4    Parsons, C.5
  • 53
    • 77649207029 scopus 로고    scopus 로고
    • Upregulation of xCT by KSHV-encoded microRNAs facilitates KSHV dissemination and persistence in an environment of oxidative stress
    • Qin, Z., Freitas, E., Sullivan, R., Mohan, S., Bacelieri, R., Branch, D., et al. (2010b). Upregulation of xCT by KSHV-encoded microRNAs facilitates KSHV dissemination and persistence in an environment of oxidative stress. PLoS Pathog. 6:e1000742. doi: 10.1371/journal.ppat.1000742.
    • (2010) PLoS Pathog , vol.6
    • Qin, Z.1    Freitas, E.2    Sullivan, R.3    Mohan, S.4    Bacelieri, R.5    Branch, D.6
  • 54
    • 43249086082 scopus 로고    scopus 로고
    • Human herpesvirus 8 infects and replicates in primary cultures of activated B lymphocytes through DC-SIGN
    • Rappocciolo, G., Hensler, H. R., Jais, M., Reinhart, T. A., Pegu, A., Jenkins, F. J., et al. (2008). Human herpesvirus 8 infects and replicates in primary cultures of activated B lymphocytes through DC-SIGN. J. Virol. 82, 4793-4806. doi: 10.1128/JVI.01587-07.
    • (2008) J. Virol , vol.82 , pp. 4793-4806
    • Rappocciolo, G.1    Hensler, H.R.2    Jais, M.3    Reinhart, T.A.4    Pegu, A.5    Jenkins, F.J.6
  • 55
    • 33144461875 scopus 로고    scopus 로고
    • A phase 1-2, prospective, double blind, randomized study of the safety and efficacy of Sulfasalazine for the treatment of progressing malignant gliomas: study protocol of [ISRCTN45828668]
    • Robe, P. A., Martin, D., Albert, A., Deprez, M., Chariot, A., and Bours, V. (2006). A phase 1-2, prospective, double blind, randomized study of the safety and efficacy of Sulfasalazine for the treatment of progressing malignant gliomas: study protocol of [ISRCTN45828668]. BMC Cancer 6:29. doi: 10.1186/1471-2407-6-29.
    • (2006) BMC Cancer , vol.6 , pp. 29
    • Robe, P.A.1    Martin, D.2    Albert, A.3    Deprez, M.4    Chariot, A.5    Bours, V.6
  • 56
    • 0037160092 scopus 로고    scopus 로고
    • Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression
    • Sasaki, H., Sato, H., Kuriyama-Matsumura, K., Sato, K., Maebara, K., Wang, H., et al. (2002). Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression. J. Biol. Chem. 277, 44765-44771. doi: 10.1074/jbc.M208704200.
    • (2002) J. Biol. Chem , vol.277 , pp. 44765-44771
    • Sasaki, H.1    Sato, H.2    Kuriyama-Matsumura, K.3    Sato, K.4    Maebara, K.5    Wang, H.6
  • 57
    • 0029057036 scopus 로고
    • Induction of cystine transport activity in mouse peritoneal macrophages by bacterial lipopolysaccharide
    • Sato, H., Fujiwara, K., Sagara, J., and Bannai, S. (1995). Induction of cystine transport activity in mouse peritoneal macrophages by bacterial lipopolysaccharide. Biochem. J. 310, 547-551.
    • (1995) Biochem. J , vol.310 , pp. 547-551
    • Sato, H.1    Fujiwara, K.2    Sagara, J.3    Bannai, S.4
  • 58
    • 0035971111 scopus 로고    scopus 로고
    • Effect of oxygen on induction of the cystine transporter by bacterial lipopolysaccharide in mouse peritoneal macrophages
    • Sato, H., Kuriyama-Matsumura, K., Hashimoto, T., Sasaki, H., Wang, H., Ishii, T., et al. (2001). Effect of oxygen on induction of the cystine transporter by bacterial lipopolysaccharide in mouse peritoneal macrophages. J. Biol. Chem. 276, 10407-10412. doi: 10.1074/jbc.M007216200.
    • (2001) J. Biol. Chem , vol.276 , pp. 10407-10412
    • Sato, H.1    Kuriyama-Matsumura, K.2    Hashimoto, T.3    Sasaki, H.4    Wang, H.5    Ishii, T.6
  • 59
    • 84859711279 scopus 로고    scopus 로고
    • Sulfasalazine for brain cancer fits
    • Sontheimer, H., and Bridges, R. J. (2012). Sulfasalazine for brain cancer fits. Expert. Opin. Investig. Drugs 21, 575-578. doi: 10.1517/13543784.2012.670634.
    • (2012) Expert. Opin. Investig. Drugs , vol.21 , pp. 575-578
    • Sontheimer, H.1    Bridges, R.J.2
  • 60
    • 0029166033 scopus 로고
    • Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease
    • Soulier, J., Grollet, L., Oksenhendler, E., Cacoub, P., Cazals-Hatem, D., Babinet, P., et al. (1995). Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease. Blood 86, 1276-1280.
    • (1995) Blood , vol.86 , pp. 1276-1280
    • Soulier, J.1    Grollet, L.2    Oksenhendler, E.3    Cacoub, P.4    Cazals-Hatem, D.5    Babinet, P.6
  • 61
    • 35448975617 scopus 로고    scopus 로고
    • Induction of cystine/glutamate transporter in bacterial lipopolysaccharide induced endotoxemia in mice
    • Taguchi, K., Tamba, M., Bannai, S., and Sato, H. (2007). Induction of cystine/glutamate transporter in bacterial lipopolysaccharide induced endotoxemia in mice. J. Inflamm. (Lond) 4, 20. doi: 10.1186/1476-9255-4-20.
    • (2007) J. Inflamm. (Lond) , vol.4 , pp. 20
    • Taguchi, K.1    Tamba, M.2    Bannai, S.3    Sato, H.4
  • 62
    • 84908241240 scopus 로고    scopus 로고
    • Interaction of KSHV with host cell surface receptors and cell entry
    • Veettil, M. V., Bandyopadhyay, C., Dutta, D., and Chandran, B. (2014). Interaction of KSHV with host cell surface receptors and cell entry. Viruses 6, 4024-4046. doi: 10.3390/v6104024.
    • (2014) Viruses , vol.6 , pp. 4024-4046
    • Veettil, M.V.1    Bandyopadhyay, C.2    Dutta, D.3    Chandran, B.4
  • 63
    • 57349163515 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus forms a multimolecular complex of integrins (αVβ5, αVβ3, and α3β1) and CD98-xCT during infection of human dermal microvascular endothelial cells, and CD98-xCT is essential for the postentry stage of infection
    • Veettil, M. V., Sadagopan, S., Sharma-Walia, N., Wang, F. Z., Raghu, H., Varga, L., et al. (2008). Kaposi's sarcoma-associated herpesvirus forms a multimolecular complex of integrins (αVβ5, αVβ3, and α3β1) and CD98-xCT during infection of human dermal microvascular endothelial cells, and CD98-xCT is essential for the postentry stage of infection. J. Virol. 82, 12126-12144. doi: 10.1128/JVI.01146-08.
    • (2008) J. Virol , vol.82 , pp. 12126-12144
    • Veettil, M.V.1    Sadagopan, S.2    Sharma-Walia, N.3    Wang, F.Z.4    Raghu, H.5    Varga, L.6
  • 64
    • 24044511771 scopus 로고    scopus 로고
    • Metabolic activation-related CD147-CD98 complex
    • Xu, D., and Hemler, M. E. (2005). Metabolic activation-related CD147-CD98 complex. Mol. Cell. Proteomics 4, 1061-1071. doi: 10.1074/mcp.M400207-MCP200.
    • (2005) Mol. Cell. Proteomics , vol.4 , pp. 1061-1071
    • Xu, D.1    Hemler, M.E.2
  • 65
    • 42449100821 scopus 로고    scopus 로고
    • Bridge linkage role played by CD98hc of anti-tumor drug resistance and cancer metastasis on cisplatin-resistant ovarian cancer cells
    • Yang, H., Zou, W., Li, Y., Chen, B., and Xin, X. (2007). Bridge linkage role played by CD98hc of anti-tumor drug resistance and cancer metastasis on cisplatin-resistant ovarian cancer cells. Cancer Biol. Ther. 6, 942-947. doi: 10.4161/cbt.6.6.4190.
    • (2007) Cancer Biol. Ther , vol.6 , pp. 942-947
    • Yang, H.1    Zou, W.2    Li, Y.3    Chen, B.4    Xin, X.5
  • 66
    • 33645804599 scopus 로고    scopus 로고
    • Role of the glutathione metabolic pathway in lung cancer treatment and prognosis: a review
    • Yang, P., Ebbert, J. O., Sun, Z., and Weinshilboum, R. M. (2006). Role of the glutathione metabolic pathway in lung cancer treatment and prognosis: a review. J. Clin. Oncol. 24, 1761-1769. doi: 10.1200/JCO.2005.02.7110.
    • (2006) J. Clin. Oncol , vol.24 , pp. 1761-1769
    • Yang, P.1    Ebbert, J.O.2    Sun, Z.3    Weinshilboum, R.M.4
  • 67
    • 77953724112 scopus 로고    scopus 로고
    • Overexpression of xCT induces up-regulation of 14-3-3β in Kaposi's sarcoma
    • Zeng, Y., Li, Y., Chen, R. S., He, X., Yang, L., and Li, W. (2010). Overexpression of xCT induces up-regulation of 14-3-3β in Kaposi's sarcoma. Biosci. Rep. 30, 277-283. doi: 10.1042/BSR20090163.
    • (2010) Biosci. Rep , vol.30 , pp. 277-283
    • Zeng, Y.1    Li, Y.2    Chen, R.S.3    He, X.4    Yang, L.5    Li, W.6
  • 68
    • 33847263980 scopus 로고    scopus 로고
    • Inhibition of CD147 gene expression via RNA interference reduces tumor cell invasion, tumorigenicity and increases chemosensitivity to paclitaxel in HO-8910pm cells
    • Zou, W., Yang, H., Hou, X., Zhang, W., Chen, B., and Xin, X. (2007). Inhibition of CD147 gene expression via RNA interference reduces tumor cell invasion, tumorigenicity and increases chemosensitivity to paclitaxel in HO-8910pm cells. Cancer Lett. 248, 211-218. doi: 10.1016/j.canlet.2006.07.005.
    • (2007) Cancer Lett , vol.248 , pp. 211-218
    • Zou, W.1    Yang, H.2    Hou, X.3    Zhang, W.4    Chen, B.5    Xin, X.6


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