RIG-I and TLR3 are both required for maximum interferon induction by influenza virus in human lung alveolar epithelial cells

Virology

Volumn 482, Issue , 2015, Pages 181-188

  Wu, Wenxin ^a   Zhang, Wei ^a   Duggan, Elizabeth S ^a   Booth, J Leland ^a   Zou, Ming Hui ^a   Metcalf, Jordan P ^a,b  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

A549; AEC; Human; Influenza; Innate immunity; Interferon; Lung; PR8; RIG I; TLR3

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; INTERFERON; INTERFERON REGULATORY FACTOR 3; RETINOIC ACID INDUCIBLE PROTEIN I; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 7; DDX58 PROTEIN, HUMAN; DEAD BOX PROTEIN; TLR3 PROTEIN, HUMAN;

A549 CELL LINE; ARTICLE; CELL ISOLATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOASSAY; IMMUNOBLOTTING; INFLUENZA VIRUS A H1N1; LUNG ALVEOLUS EPITHELIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; CELL CULTURE; EPITHELIUM CELL; GENE EXPRESSION PROFILING; GENE SILENCING; IMMUNOLOGY; INFLUENZA A VIRUS (H1N1); METABOLISM; SECRETION (PROCESS); VIROLOGY;

INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE;

CELLS, CULTURED; DEAD-BOX RNA HELICASES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; GENE EXPRESSION PROFILING; GENE KNOCKDOWN TECHNIQUES; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INTERFERONS; REAL-TIME POLYMERASE CHAIN REACTION; TOLL-LIKE RECEPTOR 3;

EID: 84927557287     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2015.03.048     Document Type: Article

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