Evolution for exogenous octanoic acid tolerance improves carboxylic acid production and membrane integrity

Metabolic Engineering

Volumn 29, Issue , 2015, Pages 180-188

  Royce, Liam A ^a   Yoon, Jong Moon ^a   Chen, Yingxi ^a   Rickenbach, Emily ^a,b   Shanks, Jacqueline V ^a   Jarboe, Laura R ^a  

^a Iowa State University   (United States)

^b IOWA STATE UNIVERSITY   (United States)

Author keywords

Fatty acids; Intracellular acidification; Membrane composition; Membrane fluidity; Membrane integrity; Membrane leakage

Indexed keywords

ACIDIFICATION; CARBOXYLIC ACIDS; CELL MEMBRANES; CYTOLOGY; ESCHERICHIA COLI; FLUIDITY; LIPIDS; MEMBRANES; METABOLIC ENGINEERING; SATURATED FATTY ACIDS; TOXICITY;

EVOLUTIONARY APPROACH; FERMENTATIVE PRODUCTION; MEMBRANE COMPOSITION; MEMBRANE FLUIDITY; MEMBRANE INTEGRITY; MEMBRANE LEAKAGES; MEMBRANE POLARIZATION; MICROBIAL BIOCATALYSTS;

FATTY ACIDS;

ALCOHOL; BUTANOL; CARBOXYLIC ACID; DECANOIC ACID; FUEL; HEXANOIC ACID; ISOBUTANOL; MEMBRANE LIPID; OCTANOIC ACID; BACTERIAL PROTEIN; OCTANOIC ACID DERIVATIVE; THIOL ESTER HYDROLASE;

ACIDIFICATION; ANAEROCOCCUS TETRADIUS; ARTICLE; CONTROLLED STUDY; DYNAMICS; ESCHERICHIA COLI; MEMBRANE COMPONENT; MEMBRANE FLUIDITY; MEMBRANE STABILIZATION; METABOLIC ENGINEERING; NONHUMAN; PRIORITY JOURNAL; RENEWABLE ENERGY; ANTIBIOTIC RESISTANCE; BIOSYNTHESIS; DIRECTED MOLECULAR EVOLUTION; DRUG EFFECTS; FIRMICUTES; GENETICS; METABOLISM; PH;

ANAEROCOCCUS TETRADIUS; ESCHERICHIA COLI;

BACTERIAL PROTEINS; CAPRYLATES; DIRECTED MOLECULAR EVOLUTION; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; FIRMICUTES; HYDROGEN-ION CONCENTRATION; THIOLESTER HYDROLASES;

EID: 84927514444     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2015.03.014     Document Type: Article

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