APOE ε4 influences β-amyloid deposition in primary progressive aphasia and speech apraxia

Alzheimer's and Dementia

Volumn 10, Issue 6, 2014, Pages 630-636

  Josephs, Keith A ^a   Duffy, Joseph R ^a   Strand, Edythe A ^a   MacHulda, Mary M ^a   Senjem, Matthew L ^a   Lowe, Val J ^a   Jack, Clifford R ^a   Whitwell, Jennifer L ^a  

^a MAYO CLINIC   (United States)

Author keywords

Apolipoprotein; Logopenic aphasia; Pittsburgh compound B; Primary progressive aphasia; Speech apraxia

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E4; PITTSBURGH COMPOUND B; 2-(4'-(METHYLAMINO)PHENYL)-6-HYDROXYBENZOTHIAZOLE; ANILINE DERIVATIVE; THIAZOLE DERIVATIVE;

ADULT; AGED; ALLELE; APRAXIA OF SPEECH; ARTICLE; DISEASE DURATION; DISEASE SEVERITY; FEMALE; FRONTOTEMPORAL DEMENTIA; GENE FREQUENCY; GENOTYPE; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; MINI MENTAL STATE EXAMINATION; POSITRON EMISSION TOMOGRAPHY; PRIMARY PROGRESSIVE APHASIA; PRIORITY JOURNAL; APRAXIA; BRAIN MAPPING; GENETICS; METABOLISM; MIDDLE AGED; SCINTISCANNING; VERY ELDERLY;

AGED; AGED, 80 AND OVER; AMYLOID BETA-PEPTIDES; ANILINE COMPOUNDS; APHASIA, PRIMARY PROGRESSIVE; APOLIPOPROTEIN E4; APRAXIAS; BRAIN MAPPING; FEMALE; HUMANS; MALE; MIDDLE AGED; POSITRON-EMISSION TOMOGRAPHY; THIAZOLES;

EID: 84927176218     PISSN: 15525260     EISSN: 15525279     Source Type: Journal    
DOI: 10.1016/j.jalz.2014.03.004     Document Type: Article

References (44)

1. E.H. Corder, A.M. Saunders, W.J. Strittmatter, D.E. Schmechel, P.C. Gaskell, and G.W. Small Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families Science 261 1993 921 923
2. T. Gomez-Isla, H.L. West, G.W. Rebeck, S.D. Harr, J.H. Growdon, and J.J. Locascio Clinical and pathological correlates of apolipoprotein E epsilon 4 in Alzheimer's disease Ann Neurol 39 1996 62 70
3. L.A. Farrer, L.A. Cupples, J.L. Haines, B. Hyman, W.A. Kukull, and R. Mayeux Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium JAMA 278 1997 1349 1356
4. G. McKhann, D. Drachman, M. Folstein, R. Katzman, D. Price, and E.M. Stadlan Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease Neurology 34 1984 939 944
5. M.L. Gorno-Tempini, A.E. Hillis, S. Weintraub, A. Kertesz, M. Mendez, and S.F. Cappa Classification of primary progressive aphasia and its variants Neurology 76 2011 1006 1014
6. J. Duffy Apraxia of speech in degenerative neurologic disease Aphasiology 20 2006 511 527
7. M.R. McNeil, R.A. Robin, and R.A. Schmidt Apraxia of speech: definition and differential diagnosis M.R.E. McNeil, Clinical management of sensorimotor speech disorders 2009 Thieme New York
8. K.A. Josephs, J.R. Duffy, E.A. Strand, M.M. Machulda, M.L. Senjem, and A.V. Master Characterizing a neurodegenerative syndrome: primary progressive apraxia of speech Brain 135 2012 1522 1536
9. K.A. Josephs, J.R. Duffy, E.A. Strand, M.M. Machulda, M.L. Senjem, and V.J. Lowe Syndromes dominated by apraxia of speech show distinct characteristics from agrammatic PPA Neurology 81 2013 337 345
10. M. Mesulam, A. Wicklund, N. Johnson, E. Rogalski, G.C. Leger, and A. Rademaker Alzheimer and frontotemporal pathology in subsets of primary progressive aphasia Ann Neurol 63 2008 709 719
11. G.D. Rabinovici, W.J. Jagust, A.J. Furst, J.M. Ogar, C.A. Racine, and E.C. Mormino Abeta amyloid and glucose metabolism in three variants of primary progressive aphasia Ann Neurol 64 2008 388 401
12. C.E. Leyton, V.L. Villemagne, S. Savage, K.E. Pike, K.J. Ballard, and O. Piguet Subtypes of progressive aphasia: application of the International Consensus Criteria and validation using beta-amyloid imaging Brain 134 2011 3030 3043
13. J.A. Knibb, J.H. Xuereb, K. Patterson, and J.R. Hodges Clinical and pathological characterization of progressive aphasia Ann Neurol 59 2006 156 165
14. V. Deramecourt, F. Lebert, B. Debachy, M.A. Mackowiak-Cordoliani, S. Bombois, and O. Kerdraon Prediction of pathology in primary progressive language and speech disorders Neurology 74 2010 42 49
15. K.A. Josephs, J.R. Duffy, E.A. Strand, J.L. Whitwell, K.F. Layton, and J.E. Parisi Clinicopathological and imaging correlates of progressive aphasia and apraxia of speech Brain 129 2006 1385 1398
16. K.A. Josephs, J.R. Hodges, J.S. Snowden, I.R. Mackenzie, M. Neumann, and D.M. Mann Neuropathological background of phenotypical variability in frontotemporal dementia Acta Neuropathol 122 2011 137 153
17. K.A. Josephs, Y. Tsuboi, N. Cookson, H. Watt, and D.W. Dickson Apolipoprotein E epsilon 4 is a determinant for Alzheimer-type pathologic features in tauopathies, synucleinopathies, and frontotemporal degeneration Arch Neurol 61 2004 1579 1584
18. R. Crook, J. Hardy, and K. Duff Single-day apolipoprotein E genotyping J Neurosci Methods 53 1994 125 127
19. A. Kertesz Western aphasia battery (Revised) 2007 PsychCorp San Antonio, Tx
20. M.F. Folstein, S.E. Folstein, and P.R. McHugh "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician J Psychiatr Res 12 1975 189 198
21. C.R. Jack Jr., V.J. Lowe, M.L. Senjem, S.D. Weigand, B.J. Kemp, and M.M. Shiung 11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment Brain 131 2008 665 680
22. N. Tzourio-Mazoyer, B. Landeau, D. Papathanassiou, F. Crivello, O. Etard, and N. Delcroix Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain Neuroimage 15 2002 273 289
23. A. Agresti, and B.A. Coull Approximate is better than "exact" for interval estimation of binomial proportions Am Stat 52 1998 119 126
24. F. Caso, B. Gesierich, M. Henry, M. Sidhu, A. LaMarre, and M. Babiak Nonfluent/agrammatic PPA with in-vivo cortical amyloidosis and Pick's disease pathology Behav Neurol 26 2013 95 106
25. M. Neumann, D.M. Sampathu, L.K. Kwong, A.C. Truax, M.C. Micsenyi, and T.T. Chou Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis Science 314 2006 130 133
26. C.R. Harrington, J. Louwagie, R. Rossau, E. Vanmechelen, R.H. Perry, and E.K. Perry Influence of apolipoprotein E genotype on senile dementia of the Alzheimer and Lewy body types. Significance for etiological theories of Alzheimer's disease Am J Pathol 145 1994 1472 1484
27. D. St Clair, J. Norrman, R. Perry, C. Yates, G. Wilcock, and A. Brookes Apolipoprotein E epsilon 4 allele frequency in patients with Lewy body dementia, Alzheimer's disease and age-matched controls Neurosci Lett 176 1994 45 46
28. M. Gearing, J.A. Schneider, G.W. Rebeck, B.T. Hyman, and S.S. Mirra Alzheimer's disease with and without coexisting Parkinson's disease changes: apolipoprotein E genotype and neuropathologic correlates Neurology 45 1995 1985 1990
29. K.A. Josephs, B.F. Boeve, J.R. Duffy, G.E. Smith, D.S. Knopman, and J.E. Parisi Atypical progressive supranuclear palsy underlying progressive apraxia of speech and nonfluent aphasia Neurocase 11 2005 283 296
30. J.S. Goldman New approaches to genetic counseling and testing for Alzheimer's disease and frontotemporal degeneration Curr Neurol Neurosci Rep 12 2012 502 510
31. K.A. Josephs, J.R. Duffy, E.A. Strand, M.M. Machulda, P. Vemuri, and M.L. Senjem Progranulin-associated PiB-negative logopenic primary progressive aphasia J Neurol 261 2014 604 614
32. E.J. Rogalski, A. Rademaker, T.M. Harrison, I. Helenowski, N. Johnson, and E. Bigio ApoE E4 is a susceptibility factor in amnestic but not aphasic dementias Alzheimer Dis Assoc Disord 25 2011 159 163
33. H. Braak, and E. Braak Neuropathological stageing of Alzheimer-related changes Acta Neuropathol 82 1991 239 259
34. C.C. Rowe, S. Ng, U. Ackermann, S.J. Gong, K. Pike, and G. Savage Imaging beta-amyloid burden in aging and dementia Neurology 68 2007 1718 1725
35. M. Lehmann, P.M. Ghosh, C. Madison, R. Laforce Jr., C. Corbetta-Rastelli, and M.W. Weiner Diverging patterns of amyloid deposition and hypometabolism in clinical variants of probable Alzheimer's disease Brain 136 2013 844 858
36. J.L. Whitwell, V.J. Lowe, J.R. Duffy, E.A. Strand, M.M. Machulda, and K. Kantarci Elevated occipital beta-amyloid deposition is associated with widespread cognitive impairment in logopenic progressive aphasia J Neurol Neurosurg Psychiatry 84 2013 1357 1364
37. A. Drzezga, T. Grimmer, G. Henriksen, M. Muhlau, R. Perneczky, and I. Miederer Effect of APOE genotype on amyloid plaque load and gray matter volume in Alzheimer disease Neurology 72 2009 1487 1494
38. R. Ossenkoppele, W.M. van der Flier, M.D. Zwan, S.F. Adriaanse, R. Boellaard, and A.D. Windhorst Differential effect of APOE genotype on amyloid load and glucose metabolism in AD dementia Neurology 80 2013 359 365
39. M. Lehmann, P.M. Ghosh, C. Madison, A. Karydas, G. Coppola, and J.P. O'Neil Greater medial temporal hypometabolism and lower cortical amyloid burden in ApoE4-positive AD patients J Neurol Neurosurg Psychiatry 85 2014 266 273
40. V.L. Villemagne, K.E. Pike, G. Chetelat, K.A. Ellis, R.S. Mulligan, and P. Bourgeat Longitudinal assessment of Abeta and cognition in aging and Alzheimer disease Ann Neurol 69 2011 181 192
41. C.C. Rowe, K.A. Ellis, M. Rimajova, P. Bourgeat, K.E. Pike, and G. Jones Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging Neurobiol Aging 31 2010 1275 1283
42. M. Landen, A. Thorsell, A. Wallin, and K. Blennow The apolipoprotein E allele epsilon 4 does not correlate with the number of senile plaques or neurofibrillary tangles in patients with Alzheimer's disease J Neurol Neurosurg Psychiatry 61 1996 352 356
43. P. Tiraboschi, L.A. Hansen, E. Masliah, M. Alford, L.J. Thal, and J. Corey-Bloom Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease Neurology 62 2004 1977 1983
44. Z. Nagy, M.M. Esiri, K.A. Jobst, C. Johnston, S. Litchfield, and E. Sim Influence of the apolipoprotein E genotype on amyloid deposition and neurofibrillary tangle formation in Alzheimer's disease Neuroscience 69 1995 757 761