메뉴 건너뛰기




Volumn 66, Issue 1, 2015, Pages 25-35

Estradiol in vivo induces changes in cardiomyocytes size in obese rats

Author keywords

Cardiac hypertrophy; Estradiol; IR; Obesity

Indexed keywords

C REACTIVE PROTEIN; ESTRADIOL; GLUCOSE; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; CHOLESTEROL; GLUCOSE BLOOD LEVEL; MAPK1 PROTEIN, RAT; MITOGEN ACTIVATED PROTEIN KINASE;

EID: 84927172355     PISSN: 00033197     EISSN: 19401574     Source Type: Journal    
DOI: 10.1177/0003319713514477     Document Type: Article
Times cited : (31)

References (75)
  • 1
    • 0347985272 scopus 로고    scopus 로고
    • Obesity-induced inflammatory changes in adipose tissue
    • Wellen KE, Hotamisligil GS. Obesity-induced inflammatory changes in adipose tissue. J Clin Invest. 2003;112(12):1785-1788.
    • (2003) J Clin Invest , vol.112 , Issue.12 , pp. 1785-1788
    • Wellen, K.E.1    Hotamisligil, G.S.2
  • 2
    • 1642633752 scopus 로고    scopus 로고
    • Inflamed about obesity
    • Lehrke M, Lazar M.A. Inflamed about obesity. Nat Med. 2004; 10(2):126-127.
    • (2004) Nat Med , vol.10 , Issue.2 , pp. 126-127
    • Lehrke, M.1    Lazar, M.A.2
  • 3
    • 0036688964 scopus 로고    scopus 로고
    • Influence of excess fat on cardiac morphology and function: Study in uncomplicated obesity
    • Iacobellis G, Ribaudo MC, Leto G, et al. Influence of excess fat on cardiac morphology and function: study in uncomplicated obesity. Obes Res. 2002;10(8):767-773.
    • (2002) Obes Res , vol.10 , Issue.8 , pp. 767-773
    • Iacobellis, G.1    Ribaudo, M.C.2    Leto, G.3
  • 4
    • 16644391590 scopus 로고    scopus 로고
    • Adapted changes in left ventricular structure and function in severe uncomplicated obesity
    • Iacobellis G, Ribaudo MC, Zappaterreno A, Iannucci CV, Di Mario U, Leonetti F. Adapted changes in left ventricular structure and function in severe uncomplicated obesity. Obes Res. 2004; 12(10):1616-1621.
    • (2004) Obes Res , vol.12 , Issue.10 , pp. 1616-1621
    • Iacobellis, G.1    Ribaudo, M.C.2    Zappaterreno, A.3    Iannucci, C.V.4    Di Mario, U.5    Leonetti, F.6
  • 5
    • 21344455935 scopus 로고    scopus 로고
    • Cardiac dysfunction induced by high-fat diet is associated with altered myocardial insulin signalling in rats
    • Ouwens DM, Boer C, Fodor M, et al. Cardiac dysfunction induced by high-fat diet is associated with altered myocardial insulin signalling in rats. Diabetologia. 2005;48(6):1229-1237.
    • (2005) Diabetologia , vol.48 , Issue.6 , pp. 1229-1237
    • Ouwens, D.M.1    Boer, C.2    Fodor, M.3
  • 6
    • 77958509514 scopus 로고    scopus 로고
    • Cardiac remodeling in a rat model of diet-induced obesity
    • Leopoldo AS, Sugizaki MM, Lima-Leopoldo AP, et al. Cardiac remodeling in a rat model of diet-induced obesity. Can J Cardiol. 2010;26(8):423-429.
    • (2010) Can J Cardiol , vol.26 , Issue.8 , pp. 423-429
    • Leopoldo, A.S.1    Sugizaki, M.M.2    Lima-Leopoldo, A.P.3
  • 8
    • 64549132904 scopus 로고    scopus 로고
    • Sex differences in the regulation of body weight
    • Shi H, Clegg DJ. Sex differences in the regulation of body weight. Physiol Behav. 2009;97(2):199-204.
    • (2009) Physiol Behav , vol.97 , Issue.2 , pp. 199-204
    • Shi, H.1    Clegg, D.J.2
  • 9
    • 84861347494 scopus 로고    scopus 로고
    • Estrogen and the cardiovascular system
    • Knowlton AA, Lee AR. Estrogen and the cardiovascular system. Pharmacol Ther. 2012;135(1):54-70.
    • (2012) Pharmacol Ther , vol.135 , Issue.1 , pp. 54-70
    • Knowlton, A.A.1    Lee, A.R.2
  • 10
    • 80052567031 scopus 로고    scopus 로고
    • Estrogen signaling and cardiovascular disease
    • Murphy E. Estrogen signaling and cardiovascular disease. Circ Res. 2011;109(6):687-696.
    • (2011) Circ Res , vol.109 , Issue.6 , pp. 687-696
    • Murphy, E.1
  • 11
    • 33645419343 scopus 로고    scopus 로고
    • Estradiol improves cardiac and hepatic function after trauma-hemorrhage: Role of enhanced heat shock protein expression
    • Szalay L, Shimizu T, Suzuki T, et al. Estradiol improves cardiac and hepatic function after trauma-hemorrhage: role of enhanced heat shock protein expression. Am J Physiol Regul Integr Comp Physiol. 2006;290(3):R812-R818.
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.290 , Issue.3 , pp. R812-R818
    • Szalay, L.1    Shimizu, T.2    Suzuki, T.3
  • 14
    • 80052742071 scopus 로고    scopus 로고
    • Estrogen receptors and the metabolic network
    • Barros RP, Gustafsson JA. Estrogen receptors and the metabolic network. Cell Metab. 2011;14(3):289-299.
    • (2011) Cell Metab , vol.14 , Issue.3 , pp. 289-299
    • Barros, R.P.1    Gustafsson, J.A.2
  • 15
    • 84891801122 scopus 로고    scopus 로고
    • Prevention of obesity and insulin resistance by estrogens requires ERalpha activation function-2 (ERalphaAF-2), whereas ERalphaAF-1 is dispensable
    • Handgraaf S, Riant E, Fabre A, et al. Prevention of obesity and insulin resistance by estrogens requires ERalpha activation function-2 (ERalphaAF-2), whereas ERalphaAF-1 is dispensable. Diabetes. 2014;62(12):4098-4108.
    • (2014) Diabetes , vol.62 , Issue.12 , pp. 4098-4108
    • Handgraaf, S.1    Riant, E.2    Fabre, A.3
  • 16
    • 0037184912 scopus 로고    scopus 로고
    • Integration of the non-genomic and genomic actions of estrogen membrane-initiated signaling by steroid to transcription and cell biology
    • Pedram A, Razandi M, Aitkenhead M, Hughes CC, Levin ER. Integration of the non-genomic and genomic actions of estrogen. membrane-initiated signaling by steroid to transcription and cell biology. J Biol Chem. 2002;277(52):50768-50775.
    • (2002) J Biol Chem , vol.277 , Issue.52 , pp. 50768-50775
    • Pedram, A.1    Razandi, M.2    Aitkenhead, M.3    Hughes, C.C.4    Levin, E.R.5
  • 17
    • 41149124315 scopus 로고    scopus 로고
    • Hypothetical mechanism of sodium pump regulation by estradiol under primary hypertension
    • Sudar E, Velebit J, Gluvic Z, et al. Hypothetical mechanism of sodium pump regulation by estradiol under primary hypertension. J Theor Biol. 2008;251(4):584-592.
    • (2008) J Theor Biol , vol.251 , Issue.4 , pp. 584-592
    • Sudar, E.1    Velebit, J.2    Gluvic, Z.3
  • 18
    • 7944232490 scopus 로고    scopus 로고
    • Ang II attenuates IGF-1-stimulated Na+, K(+)-ATPase activity via PI3K/Akt pathway in vascular smooth muscle cells
    • Isenovic ER, Meng Y, Jamali N, Milivojevic N, Sowers J.R. Ang II attenuates IGF-1-stimulated Na+, K(+)-ATPase activity via PI3K/Akt pathway in vascular smooth muscle cells. Int J Mol Med. 2004;13(6):915-922.
    • (2004) Int J Mol Med , vol.13 , Issue.6 , pp. 915-922
    • Isenovic, E.R.1    Meng, Y.2    Jamali, N.3    Milivojevic, N.4    Sowers, J.R.5
  • 19
    • 2042487998 scopus 로고    scopus 로고
    • The isoflavone metabolite cistetrahydrodaidzein inhibits ERK-1 activation and proliferation in human vascular smooth muscle cells
    • Ling S, Dai A, Williams MR, et al. The isoflavone metabolite cistetrahydrodaidzein inhibits ERK-1 activation and proliferation in human vascular smooth muscle cells. J Cardiovasc Pharmacol. 2004;43(5):622-628.
    • (2004) J Cardiovasc Pharmacol , vol.43 , Issue.5 , pp. 622-628
    • Ling, S.1    Dai, A.2    Williams, M.R.3
  • 20
    • 0035947744 scopus 로고    scopus 로고
    • Myocardial Akt activation and gender: Increased nuclear activity in females versus males
    • Camper-Kirby D, Welch S, Walker A, et al. Myocardial Akt activation and gender: increased nuclear activity in females versus males. Circ Res. 2001;88(10):1020-1027.
    • (2001) Circ Res , vol.88 , Issue.10 , pp. 1020-1027
    • Camper-Kirby, D.1    Welch, S.2    Walker, A.3
  • 21
    • 77649162900 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase 1/2 (ERK1/2) signaling in cardiac hypertrophy
    • Kehat I, Molkentin JD. Extracellular signal-regulated kinase 1/2 (ERK1/2) signaling in cardiac hypertrophy. Ann N Y Acad Sci. 2010;1188:96-102.
    • (2010) Ann N y Acad Sci , vol.1188 , pp. 96-102
    • Kehat, I.1    Molkentin, J.D.2
  • 22
    • 77954144200 scopus 로고    scopus 로고
    • Effects of treadmill exercise training on liver fat accumulation and estrogen receptor alpha expression in intact and ovariectomized rats with or without estrogen replacement treatment
    • Hao L, Wang Y, Duan Y, Bu S. Effects of treadmill exercise training on liver fat accumulation and estrogen receptor alpha expression in intact and ovariectomized rats with or without estrogen replacement treatment. Eur J Appl Physiol. 2010;109(5):879-886.
    • (2010) Eur J Appl Physiol , vol.109 , Issue.5 , pp. 879-886
    • Hao, L.1    Wang, Y.2    Duan, Y.3    Bu, S.4
  • 23
    • 0027185498 scopus 로고
    • The effects of oestrogen and progesterone on insulin sensitivity in female rats
    • Kumagai S, Holmang A, Bjorntorp P. The effects of oestrogen and progesterone on insulin sensitivity in female rats. Acta Physiol Scand. 1993;149(1):91-97.
    • (1993) Acta Physiol Scand , vol.149 , Issue.1 , pp. 91-97
    • Kumagai, S.1    Holmang, A.2    Bjorntorp, P.3
  • 24
    • 83655201131 scopus 로고    scopus 로고
    • Oestrogen alters adipocyte biology and protects female mice from adipocyte inflammation and insulin resistance
    • Stubbins RE, Najjar K, Holcomb VB, Hong J, Nunez NP. Oestrogen alters adipocyte biology and protects female mice from adipocyte inflammation and insulin resistance. Diabetes Obes Metab. 2012;14(1):58-66.
    • (2012) Diabetes Obes Metab , vol.14 , Issue.1 , pp. 58-66
    • Stubbins, R.E.1    Najjar, K.2    Holcomb, V.B.3    Hong, J.4    Nunez, N.P.5
  • 25
    • 0031762310 scopus 로고    scopus 로고
    • Insulin sensitivity and cardiovascular risk factors in ovariectomized monkeys with estradiol alone or combined with nomegestrol acetate
    • Wagner JD, Thomas MJ, Williams JK, Zhang L, Greaves KA, Cefalu WT. Insulin sensitivity and cardiovascular risk factors in ovariectomized monkeys with estradiol alone or combined with nomegestrol acetate. J Clin EndocrinolMetab. 1998;83(3):896-901.
    • (1998) J Clin EndocrinolMetab , vol.83 , Issue.3 , pp. 896-901
    • Wagner, J.D.1    Thomas, M.J.2    Williams, J.K.3    Zhang, L.4    Greaves, K.A.5    Cefalu, W.T.6
  • 26
    • 84873040492 scopus 로고    scopus 로고
    • Estrogen treatment after ovariectomy protects against fatty liver and may improve pathwayselective insulin resistance
    • Zhu L, Brown WC, Cai Q, et al. Estrogen treatment after ovariectomy protects against fatty liver and may improve pathwayselective insulin resistance. Diabetes. 2013;62(2):424-434.
    • (2013) Diabetes , vol.62 , Issue.2 , pp. 424-434
    • Zhu, L.1    Brown, W.C.2    Cai, Q.3
  • 27
    • 79952535037 scopus 로고    scopus 로고
    • Interference between insulin and estradiol signaling pathways in the regulation of cardiac eNOS and Na(+)/K(+)-ATPase
    • Koricanac G, Tepavcevic S, Zakula Z, Milosavljevic T, Stojiljkovic M, Isenovic ER. Interference between insulin and estradiol signaling pathways in the regulation of cardiac eNOS and Na(+)/K(+)-ATPase. Eur J Pharmacol. 2011;655(1-3):23-30.
    • (2011) Eur J Pharmacol , vol.655 , Issue.1-3 , pp. 23-30
    • Koricanac, G.1    Tepavcevic, S.2    Zakula, Z.3    Milosavljevic, T.4    Stojiljkovic, M.5    Isenovic, E.R.6
  • 29
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28(7):412-419.
    • (1985) Diabetologia , vol.28 , Issue.7 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 30
    • 0001558285 scopus 로고
    • The colorimetric micro-determination of nonesterified fatty acids in plasma
    • Duncombe WG. The colorimetric micro-determination of nonesterified fatty acids in plasma. Clin Chim Acta. 1964;9:122-125.
    • (1964) Clin Chim Acta , vol.9 , pp. 122-125
    • Duncombe, W.G.1
  • 31
    • 0019304939 scopus 로고
    • Colorimetric determination of phospholipids with ammonium ferrothiocyanate
    • Stewart JC. Colorimetric determination of phospholipids with ammonium ferrothiocyanate. Anal Biochem. 1980;104(1):10-14.
    • (1980) Anal Biochem , vol.104 , Issue.1 , pp. 10-14
    • Stewart, J.C.1
  • 32
    • 0027507180 scopus 로고
    • Histological study of the internal mammary artery with emphasis on its suitability as a coronary artery bypass graft
    • van Son JA, Smedts F, de Wilde PC, et al. Histological study of the internal mammary artery with emphasis on its suitability as a coronary artery bypass graft. Ann Thorac Surg. 1993;55(1): 106-113.
    • (1993) Ann Thorac Surg , vol.55 , Issue.1 , pp. 106-113
    • Van Son, J.A.1    Smedts, F.2    De Wilde, P.C.3
  • 33
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970;227(5259): 680-685.
    • (1970) Nature , vol.227 , Issue.5259 , pp. 680-685
    • Laemmli, U.K.1
  • 34
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A. 1979;76(9): 4350-4354.
    • (1979) Proc Natl Acad Sci U S A , vol.76 , Issue.9 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 35
    • 0019551730 scopus 로고
    • "Western blotting": Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A
    • Burnette WN. "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal Biochem. 1981;112(2):195-203.
    • (1981) Anal Biochem , vol.112 , Issue.2 , pp. 195-203
    • Burnette, W.N.1
  • 36
    • 59849128882 scopus 로고    scopus 로고
    • Estrogen attenuates left ventricular and cardiomyocyte hypertrophy by an estrogen receptordependent pathway that increases calcineurin degradation
    • Donaldson C, Eder S, Baker C, et al. Estrogen attenuates left ventricular and cardiomyocyte hypertrophy by an estrogen receptordependent pathway that increases calcineurin degradation. Circ Res. 2009;104(2):265-275.
    • (2009) Circ Res , vol.104 , Issue.2 , pp. 265-275
    • Donaldson, C.1    Eder, S.2    Baker, C.3
  • 37
    • 84857542727 scopus 로고    scopus 로고
    • Effects of estrogen on cardiovascular injury in ovariectomized female DahlS.Z-Lepr(fa)/ Lepr(fa) rats as a new animal model of metabolic syndrome
    • Murase T, Hattori T, Ohtake M, et al. Effects of estrogen on cardiovascular injury in ovariectomized female DahlS.Z-Lepr(fa)/ Lepr(fa) rats as a new animal model of metabolic syndrome. Hypertension. 2012;59(3):694-704.
    • (2012) Hypertension , vol.59 , Issue.3 , pp. 694-704
    • Murase, T.1    Hattori, T.2    Ohtake, M.3
  • 38
    • 4944237210 scopus 로고    scopus 로고
    • 17beta-estradiol reduces cardiomyocyte apoptosis in vivo and in vitro via activation of phospho-inositide-3 kinase/Akt signaling
    • Patten RD, Pourati I, AronovitzMJ, et al. 17beta-estradiol reduces cardiomyocyte apoptosis in vivo and in vitro via activation of phospho-inositide-3 kinase/Akt signaling. Circ Res. 2004;95(7): 692-699.
    • (2004) Circ Res , vol.95 , Issue.7 , pp. 692-699
    • Patten, R.D.1    Pourati, I.2    Aronovitz, M.J.3
  • 39
    • 0030980912 scopus 로고    scopus 로고
    • Estradiol, administered acutely, protects ischemic myocardium in both female and male rabbits
    • Hale SL, Birnbaum Y, Kloner RA. Estradiol, administered acutely, protects ischemic myocardium in both female and male rabbits. J Cardiovasc Pharmacol Ther. 1997;2(1):47-52.
    • (1997) J Cardiovasc Pharmacol Ther , vol.2 , Issue.1 , pp. 47-52
    • Hale, S.L.1    Birnbaum, Y.2    Kloner, R.A.3
  • 40
    • 84883467300 scopus 로고    scopus 로고
    • Health-risk factors and the prevalence of hypertension: Crosssectional findings from a national cohort of 87,143 Thai open university students
    • Thawornchaisit P, de Looze F, Reid CM, Seubsman SA, Sleigh A. Health-risk factors and the prevalence of hypertension: crosssectional findings from a national cohort of 87,143 Thai open university students. Glob J Health Sci. 2013;5(4):126-141.
    • (2013) Glob J Health Sci , vol.5 , Issue.4 , pp. 126-141
    • Thawornchaisit, P.1    De Looze, F.2    Reid, C.M.3    Seubsman, S.A.4    Sleigh, A.5
  • 41
    • 0032944145 scopus 로고    scopus 로고
    • Effect of short-term hormone replacement therapy on left ventricular mass and contractile function
    • Sites CK, Tischler MD, Blackman JA, et al. Effect of short-term hormone replacement therapy on left ventricular mass and contractile function. Fertil Steril. 1999;71(1):137-143.
    • (1999) Fertil Steril , vol.71 , Issue.1 , pp. 137-143
    • Sites, C.K.1    Tischler, M.D.2    Blackman, J.A.3
  • 42
    • 0037637653 scopus 로고    scopus 로고
    • 17-beta-estradiol increases cardiac remodeling and mortality in mice with myocardial infarction
    • van Eickels M, Patten RD, Aronovitz MJ, et al. 17-beta-estradiol increases cardiac remodeling and mortality in mice with myocardial infarction. J Am Coll Cardiol. 2003;41(11):2084-2092.
    • (2003) J Am Coll Cardiol , vol.41 , Issue.11 , pp. 2084-2092
    • Van Eickels, M.1    Patten, R.D.2    Aronovitz, M.J.3
  • 43
    • 34248326991 scopus 로고    scopus 로고
    • Influence of dietary fatty acids composition, level of dietary fat and feeding period on some parameters of androgen metabolism in male rats
    • Gromadzka-Ostrowska J, Przepiorka M, Romanowicz K. Influence of dietary fatty acids composition, level of dietary fat and feeding period on some parameters of androgen metabolism in male rats. Reprod Biol. 2002;2(3):277-293.
    • (2002) Reprod Biol , vol.2 , Issue.3 , pp. 277-293
    • Gromadzka-Ostrowska, J.1    Przepiorka, M.2    Romanowicz, K.3
  • 44
    • 80052702601 scopus 로고    scopus 로고
    • N-myc downstream-regulated gene 2, a novel estrogen-targeted gene, is involved in the regulation of Na+/K+-ATPase
    • Li Y, Yang J, Li S, et al. N-myc downstream-regulated gene 2, a novel estrogen-targeted gene, is involved in the regulation of Na+/K+-ATPase. J Biol Chem. 2011;286(37):32289-32299.
    • (2011) J Biol Chem , vol.286 , Issue.37 , pp. 32289-32299
    • Li, Y.1    Yang, J.2    Li, S.3
  • 45
    • 84884186424 scopus 로고    scopus 로고
    • Effects of obesity and estradiol on Na+/K+-ATPase and their relevance to cardiovascular diseases
    • Obradovic M, Bjelogrlic P, Rizzo M, et al. Effects of obesity and estradiol on Na+/K+-ATPase and their relevance to cardiovascular diseases. J Endocrinol. 2013;218(3):R13-R23.
    • (2013) J Endocrinol , vol.218 , Issue.3 , pp. R13-R23
    • Obradovic, M.1    Bjelogrlic, P.2    Rizzo, M.3
  • 48
    • 84878556288 scopus 로고    scopus 로고
    • Loss of estrogen receptor alpha signaling leads to insulin resistance and obesity in young and adult female mice
    • Manrique C, Lastra G, Habibi J, Mugerfeld I, Garro M, Sowers J.R. Loss of estrogen receptor alpha signaling leads to insulin resistance and obesity in young and adult female mice. Cardiorenal Med. 2012;2(3):200-210.
    • (2012) Cardiorenal Med , vol.2 , Issue.3 , pp. 200-210
    • Manrique, C.1    Lastra, G.2    Habibi, J.3    Mugerfeld, I.4    Garro, M.5    Sowers, J.R.6
  • 49
    • 79954461307 scopus 로고    scopus 로고
    • In vivo stimulation of oestrogen receptor alpha increases insulin-stimulated skeletal muscle glucose uptake
    • Gorres BK, Bomhoff GL, Morris JK, Geiger PC. In vivo stimulation of oestrogen receptor alpha increases insulin-stimulated skeletal muscle glucose uptake. J Physiol. 2011;589(pt 8):2041-2054.
    • (2011) J Physiol , vol.589 , pp. 2041-2054
    • Gorres, B.K.1    Bomhoff, G.L.2    Morris, J.K.3    Geiger, P.C.4
  • 50
    • 66449105068 scopus 로고    scopus 로고
    • Estrogens protect against high-fat diet-induced insulin resistance and glucose intolerance in mice
    • Riant E, Waget A, Cogo H, Arnal JF, Burcelin R, Gourdy P. Estrogens protect against high-fat diet-induced insulin resistance and glucose intolerance in mice. Endocrinology. 2009;150(5): 2109-2117.
    • (2009) Endocrinology , vol.150 , Issue.5 , pp. 2109-2117
    • Riant, E.1    Waget, A.2    Cogo, H.3    Arnal, J.F.4    Burcelin, R.5    Gourdy, P.6
  • 51
    • 56049110515 scopus 로고    scopus 로고
    • Mechanisms of antidiabetogenic and body weight-lowering effects of estrogen in high-fat diet-fed mice
    • Bryzgalova G, Lundholm L, Portwood N, et al. Mechanisms of antidiabetogenic and body weight-lowering effects of estrogen in high-fat diet-fed mice. Am J Physiol Endocrinol Metab. 2008;295(4):E904-E912.
    • (2008) Am J Physiol Endocrinol Metab , vol.295 , Issue.4 , pp. E904-E912
    • Bryzgalova, G.1    Lundholm, L.2    Portwood, N.3
  • 52
    • 63149148931 scopus 로고    scopus 로고
    • Impact of estradiol on insulin signaling in the rat heart
    • Koricanac G, Milosavljevic T, Stojiljkovic M, et al. Impact of estradiol on insulin signaling in the rat heart. Cell Biochem Funct. 2009;27(2):102-110.
    • (2009) Cell Biochem Funct , vol.27 , Issue.2 , pp. 102-110
    • Koricanac, G.1    Milosavljevic, T.2    Stojiljkovic, M.3
  • 53
    • 77950343252 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
    • Hotamisligil GS. Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell. 2010;140(6):900-917.
    • (2010) Cell , vol.140 , Issue.6 , pp. 900-917
    • Hotamisligil, G.S.1
  • 54
    • 84874620881 scopus 로고    scopus 로고
    • How estrogens prevent from lipid-induced insulin resistance
    • Jelenik T, Roden M. How estrogens prevent from lipid-induced insulin resistance. Endocrinology. 2013;154(3):989-992.
    • (2013) Endocrinology , vol.154 , Issue.3 , pp. 989-992
    • Jelenik, T.1    Roden, M.2
  • 55
    • 33644972032 scopus 로고    scopus 로고
    • Muscle triglycerides and mitochondrial function: Possible mechanisms for the development of type 2 diabetes
    • Roden M. Muscle triglycerides and mitochondrial function: possible mechanisms for the development of type 2 diabetes. Int J Obes (Lond). 2005;29 suppl 2:S111-S115.
    • (2005) Int J Obes (Lond) , vol.29 , Issue.2 , pp. S111-S115
    • Roden, M.1
  • 56
    • 77953868236 scopus 로고    scopus 로고
    • Lipid-induced insulin resistance: Unravelling the mechanism
    • Samuel VT, Petersen KF, Shulman GI. Lipid-induced insulin resistance: unravelling the mechanism. Lancet. 2010;375(9733): 2267-2277.
    • (2010) Lancet , vol.375 , Issue.9733 , pp. 2267-2277
    • Samuel, V.T.1    Petersen, K.F.2    Shulman, G.I.3
  • 57
    • 0042315364 scopus 로고    scopus 로고
    • Cardiac lipid accumulation associated with diastolic dysfunction in obese mice
    • Christoffersen C, Bollano E, Lindegaard ML, et al. Cardiac lipid accumulation associated with diastolic dysfunction in obese mice. Endocrinology. 2003;144(8):3483-3490.
    • (2003) Endocrinology , vol.144 , Issue.8 , pp. 3483-3490
    • Christoffersen, C.1    Bollano, E.2    Lindegaard, M.L.3
  • 58
    • 84867147394 scopus 로고    scopus 로고
    • Effects of pioglitazone on high-fatdiet- induced ventricular remodeling and dysfunction in rats
    • Tian YQ, Li S S, Su XD, et al. Effects of pioglitazone on high-fatdiet- induced ventricular remodeling and dysfunction in rats. J Cardiovasc Pharmacol Ther. 2012;17(2):223-228.
    • (2012) J Cardiovasc Pharmacol Ther , vol.17 , Issue.2 , pp. 223-228
    • Tian, Y.Q.1    Li, S.S.2    Su, X.D.3
  • 59
    • 35048878739 scopus 로고    scopus 로고
    • Effect of pioglitazone therapy on myocardial and hepatic steatosis in insulin-treated patients with type 2 diabetes
    • Zib I, Jacob AN, Lingvay I, et al. Effect of pioglitazone therapy on myocardial and hepatic steatosis in insulin-treated patients with type 2 diabetes. J Investig Med. 2007;55(5):230-236.
    • (2007) J Investig Med , vol.55 , Issue.5 , pp. 230-236
    • Zib, I.1    Jacob, A.N.2    Lingvay, I.3
  • 60
    • 0034652225 scopus 로고    scopus 로고
    • Lipotoxic heart disease in obese rats: Implications for human obesity
    • Zhou YT, Grayburn P, Karim A, et al. Lipotoxic heart disease in obese rats: implications for human obesity. Proc Natl Acad Sci U S A. 2000;97(4):1784-1789.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.4 , pp. 1784-1789
    • Zhou, Y.T.1    Grayburn, P.2    Karim, A.3
  • 61
    • 1642505593 scopus 로고    scopus 로고
    • Estrogen replacement reverses the hepatic steatosis phenotype in the male aromatase knockout mouse
    • Hewitt KN, Pratis K, Jones ME, Simpson ER. Estrogen replacement reverses the hepatic steatosis phenotype in the male aromatase knockout mouse. Endocrinology. 2004;145(4):1842-1848.
    • (2004) Endocrinology , vol.145 , Issue.4 , pp. 1842-1848
    • Hewitt, K.N.1    Pratis, K.2    Jones, M.E.3    Simpson, E.R.4
  • 62
    • 84884418355 scopus 로고    scopus 로고
    • Anti-atherogenic effects of 17beta-estradiol
    • Resanovic I, Rizzo M, Zafirovic S, et al. Anti-atherogenic effects of 17beta-estradiol. Horm Metab Res. 2013;45(10):701-708.
    • (2013) Horm Metab Res , vol.45 , Issue.10 , pp. 701-708
    • Resanovic, I.1    Rizzo, M.2    Zafirovic, S.3
  • 63
    • 33847793319 scopus 로고    scopus 로고
    • Silencing of estrogen receptor alpha in the ventromedial nucleus of hypothalamus leads to metabolic syndrome
    • Musatov S, Chen W, Pfaff DW, et al. Silencing of estrogen receptor alpha in the ventromedial nucleus of hypothalamus leads to metabolic syndrome. Proc Natl Acad Sci U S A. 2007;104(7): 2501-2506.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.7 , pp. 2501-2506
    • Musatov, S.1    Chen, W.2    Pfaff, D.W.3
  • 64
    • 33746023956 scopus 로고    scopus 로고
    • Inhibition of cardiac PGC-1alpha expression abolishes ERbeta agonist-mediated cardioprotection following trauma-hemorrhage
    • Hsieh YC, Choudhry MA, Yu H P, et al. Inhibition of cardiac PGC-1alpha expression abolishes ERbeta agonist-mediated cardioprotection following trauma-hemorrhage. FASEB J. 2006;20(8): 1109-1117.
    • (2006) FASEB J , vol.20 , Issue.8 , pp. 1109-1117
    • Hsieh, Y.C.1    Choudhry, M.A.2    Yu, H.P.3
  • 65
    • 84867333702 scopus 로고    scopus 로고
    • Estradiol enhances effects of fructose rich diet on cardiac fatty acid transporter CD36 and triglycerides accumulation
    • Koricanac G, Tepavcevic S, Romic S, et al. Estradiol enhances effects of fructose rich diet on cardiac fatty acid transporter CD36 and triglycerides accumulation. Eur J Pharmacol. 2012; 694(1-3):127-134.
    • (2012) Eur J Pharmacol , vol.694 , Issue.1-3 , pp. 127-134
    • Koricanac, G.1    Tepavcevic, S.2    Romic, S.3
  • 66
    • 79960698563 scopus 로고    scopus 로고
    • Interaction between insulin and estradiol in regulation of cardiac glucose and free fatty acid transporters
    • Tepavcevic S, Koricanac G, Zakula Z, Milosavljevic T, Stojiljkovic M, Isenovic ER. Interaction between insulin and estradiol in regulation of cardiac glucose and free fatty acid transporters. Horm Metab Res. 2011;43(8):524-530.
    • (2011) Horm Metab Res , vol.43 , Issue.8 , pp. 524-530
    • Tepavcevic, S.1    Koricanac, G.2    Zakula, Z.3    Milosavljevic, T.4    Stojiljkovic, M.5    Isenovic, E.R.6
  • 67
    • 12944276957 scopus 로고    scopus 로고
    • Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity
    • Jones ME, Thorburn AW, Britt KL, et al. Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity. Proc Natl Acad Sci U S A. 2000;97(23):12735-12740.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.23 , pp. 12735-12740
    • Jones, M.E.1    Thorburn, A.W.2    Britt, K.L.3
  • 68
    • 0028258976 scopus 로고
    • Physiological levels of estradiol stimulate plasma high density lipoprotein2 cholesterol levels in normal men
    • Bagatell CJ, Knopp RH, Rivier JE, Bremner WJ. Physiological levels of estradiol stimulate plasma high density lipoprotein2 cholesterol levels in normal men. J Clin Endocrinol Metab. 1994; 78(4):855-861.
    • (1994) J Clin Endocrinol Metab , vol.78 , Issue.4 , pp. 855-861
    • Bagatell, C.J.1    Knopp, R.H.2    Rivier, J.E.3    Bremner, W.J.4
  • 69
    • 84862778579 scopus 로고    scopus 로고
    • Role of endogenous estrogen on the incidence of coronary heart disease in men
    • Zheng H, Li Y, Dai W, Wei C, Sun K, Tong Y. Role of endogenous estrogen on the incidence of coronary heart disease in men. Angiology. 2012;63(8):591-596.
    • (2012) Angiology , vol.63 , Issue.8 , pp. 591-596
    • Zheng, H.1    Li, Y.2    Dai, W.3    Wei, C.4    Sun, K.5    Tong, Y.6
  • 70
    • 0031847271 scopus 로고    scopus 로고
    • An investigation of the relationship between estrogen, estrogen metabolites and blood cholesterol levels in ovariectomized rats
    • Liu D, Bachmann KA. An investigation of the relationship between estrogen, estrogen metabolites and blood cholesterol levels in ovariectomized rats. J Pharmacol Exp Ther. 1998;286(1): 561-568.
    • (1998) J Pharmacol Exp Ther , vol.286 , Issue.1 , pp. 561-568
    • Liu, D.1    Bachmann, K.A.2
  • 71
    • 84867041524 scopus 로고    scopus 로고
    • Metabolic effects of estrogen and / or insulin in ovariectomized experimentally diabetic rats
    • El-Nasr A, Diab F, Bahgat N, Ahmed M, Thabet S, El-Dakkak S. Metabolic effects of estrogen and / or insulin in ovariectomized experimentally diabetic rats. J Am Sci. 2011;7(2):432-444.
    • (2011) J Am Sci , vol.7 , Issue.2 , pp. 432-444
    • El-Nasr, A.1    Diab, F.2    Bahgat, N.3    Ahmed, M.4    Thabet, S.5    El-Dakkak, S.6
  • 72
    • 31444455757 scopus 로고    scopus 로고
    • 17-beta-Estradiol decreases p38 MAPK-mediated myocardial inflammation and dysfunction following acute ischemia
    • Wang M, Tsai BM, Reiger KM, Brown JW, Meldrum DR. 17-beta-Estradiol decreases p38 MAPK-mediated myocardial inflammation and dysfunction following acute ischemia. J Mol Cell Cardiol. 2006;40(2):205-212.
    • (2006) J Mol Cell Cardiol , vol.40 , Issue.2 , pp. 205-212
    • Wang, M.1    Tsai, B.M.2    Reiger, K.M.3    Brown, J.W.4    Meldrum, D.R.5
  • 73
    • 84871727576 scopus 로고    scopus 로고
    • Estradiol inhibits vascular endothelial cells pro-inflammatory activation induced by C-reactive protein
    • Cossette E, Cloutier I, Tardif K, DonPierre G, Tanguay JF. Estradiol inhibits vascular endothelial cells pro-inflammatory activation induced by C-reactive protein. Mol Cell Biochem. 2013; 373(1-2):137-147.
    • (2013) Mol Cell Biochem , vol.373 , Issue.1-2 , pp. 137-147
    • Cossette, E.1    Cloutier, I.2    Tardif, K.3    Donpierre, G.4    Tanguay, J.F.5
  • 74
    • 0037426399 scopus 로고    scopus 로고
    • C-reactive protein upregulates angiotensin type 1 receptors in vascular smooth muscle
    • Wang CH, Li SH, Weisel RD, et al. C-reactive protein upregulates angiotensin type 1 receptors in vascular smooth muscle. Circulation. 2003;107(13):1783-1790.
    • (2003) Circulation , vol.107 , Issue.13 , pp. 1783-1790
    • Wang, C.H.1    Li, S.H.2    Weisel, R.D.3
  • 75
    • 0034383952 scopus 로고    scopus 로고
    • The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice
    • Bueno OF, De Windt LJ, Tymitz KM, et al. The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice. EMBO J. 2000;19(23):6341-6350.
    • (2000) EMBO J , vol.19 , Issue.23 , pp. 6341-6350
    • Bueno, O.F.1    De Windt, L.J.2    Tymitz, K.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.