The Isoflavone Metabolite Cis-Tetrahydrodaidzein Inhibits ERK-1 Activation and Proliferation in Human Vascular Smooth Muscle Cells

Journal of Cardiovascular Pharmacology

Volumn 43, Issue 5, 2004, Pages 622-628

  Ling, Shanhong ^a   Dai, Aozhi ^a   Williams, Maro R I ^a   Husband, Alan J ^b   Nestel, Paul J ^a   Komesaroff, Paul A ^a   Sudhir, Krishnankutty ^a,c,d  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b Novogen Limited   (Australia)

^c STANFORD UNIVERSITY   (United States)

^d STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Estrogen receptors; Mitogen activated protein kinase; Phytoestrogens; Proliferation; Vascular smooth muscle

Indexed keywords

DNA; ESTRADIOL; ESTROGEN RECEPTOR; FULVESTRANT; ISOFLAVONE DERIVATIVE; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PHYTOESTROGEN; PLATELET DERIVED GROWTH FACTOR; TETRAHYDRODAIDZEIN; UNCLASSIFIED DRUG;

ARTICLE; CASE REPORT; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SYNTHESIS; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; ENZYME INHIBITION; FEMALE; HEART PROTECTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; ENZYME INHIBITORS; FEMALE; HUMANS; ISOFLAVONES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAMMARY ARTERIES; MAP KINASE KINASE 4; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MUSCLE, SMOOTH, VASCULAR; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTORS, ESTROGEN;

EID: 2042487998     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200405000-00003     Document Type: Article

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