Resveratrol analogue (E)-8-acetoxy-2-[2-(3,4-diacetoxyphenyl) ethenyl]-quinazoline induces G2/M cell cycle arrest through the activation of ATM/ATR in human cervical carcinoma HeLa cells

Oncology Reports

Volumn 33, Issue 5, 2015, Pages 2639-2647

  Kim, Jong Yun ^a,c   Choi, Hye Eun ^a,b   Lee, Hwi Ho ^a,b   Shin, Ji Sun ^a,d   Shin, Dong Hyun ^a,c   Choi, Jung Hye ^a,b   Lee, Yong Sup ^a,b   Lee, Kyung Tae ^a,b  

^a Kyung Hee University   (South Korea)

^b Kyung Hee University   (South Korea)

^c Department of Biomedical Science   (South Korea)

^d Biomedical Science Institute   (South Korea)

Author keywords

ATM ATR; Chk1 Chk2; G2 M arrest; P53; Resveratrol; Styrylquinazoline

Indexed keywords

8 ACETOXY 2 [2 (3,4 DIACETOXYPHENYL)ETHENYL]QUINAZOLINE; ANTINEOPLASTIC AGENT; ATM PROTEIN; ATR PROTEIN; CAFFEINE; CELL CYCLE PROTEIN; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; PROTEIN CDC25C; PROTEIN P53; RESVERATROL; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ATM PROTEIN, HUMAN; ATR PROTEIN, HUMAN; CDC25C PROTEIN, HUMAN; CDK1 PROTEIN, HUMAN; CDKN1A PROTEIN, HUMAN; CHEK2 PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; PROTEIN KINASE; PROTEIN TYROSINE PHOSPHATASE; QUINAZOLINE DERIVATIVE; STILBENE DERIVATIVE; TP53 PROTEIN, HUMAN;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DNA DAMAGE; DNA DETERMINATION; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; ENZYME PHOSPHORYLATION; FEMALE; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; HELA CELL LINE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; CARCINOMA; CELL CYCLE CHECKPOINT; CELL CYCLE G2 PHASE; CELL DIVISION; DRUG EFFECTS; GENETICS; PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; UTERINE CERVIX TUMOR;

ATAXIA TELANGIECTASIA MUTATED PROTEINS; CARCINOMA; CDC25 PHOSPHATASES; CELL CYCLE CHECKPOINTS; CELL DIVISION; CHECKPOINT KINASE 2; CYCLIN B1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASES; DNA DAMAGE; FEMALE; G2 PHASE; HELA CELLS; HUMANS; PHOSPHORYLATION; PROTEIN KINASES; QUINAZOLINES; SIGNAL TRANSDUCTION; STILBENES; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION; UTERINE CERVICAL NEOPLASMS;

EID: 84927153495     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2015.3871     Document Type: Article

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