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Volumn 137, Issue 7, 2015, Pages 1528-1538

Mutant p53 expression in fallopian tube epithelium drives cell migration

Author keywords

fallopian tube; high grade serous cancer; p53 mutation

Indexed keywords

ALISERTIB; AURORA A KINASE; AURORA B KINASE; COMPLEMENTARY DNA; CYTOKERATIN 8; OVIDUCTAL GLYCOPROTEIN 1; OVIDUCTIN; POLO LIKE KINASE 4; PROTEIN MDM2; PROTEIN P53; TRANSCRIPTION FACTOR PAX8; TRANSCRIPTION FACTOR SLUG; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; KRAS2 PROTEIN, MOUSE; PROTEIN P21;

EID: 84927130471     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.29528     Document Type: Article
Times cited : (40)

References (50)
  • 1
    • 84964651268 scopus 로고    scopus 로고
    • Society AC. American Cancer Society.
    • Society AC. Cancer facts and figures 2014. American Cancer Society, www.cancer.org, 2014.
    • (2014) Cancer Facts and Figures 2014
  • 2
    • 39749171410 scopus 로고    scopus 로고
    • Early events in the pathogenesis of epithelial ovarian cancer
    • Landen CN, Jr, Birrer MJ, Sood AK., Early events in the pathogenesis of epithelial ovarian cancer. J Clin Oncol 2008; 26: 995-1005.
    • (2008) J Clin Oncol , vol.26 , pp. 995-1005
    • Landen, C.N.1    Birrer, M.J.2    Sood, A.K.3
  • 3
    • 33645225423 scopus 로고    scopus 로고
    • The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome
    • Medeiros F, Muto MG, Lee Y, et al., The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome. Am J Surg Pathol 2006; 30: 230-6.
    • (2006) Am J Surg Pathol , vol.30 , pp. 230-236
    • Medeiros, F.1    Muto, M.G.2    Lee, Y.3
  • 4
    • 0035175430 scopus 로고    scopus 로고
    • Dysplastic changes in prophylactically removed fallopian tubes of women predisposed to developing ovarian cancer
    • Piek JM, van Diest PJ, Zweemer RP, et al., Dysplastic changes in prophylactically removed fallopian tubes of women predisposed to developing ovarian cancer. J Pathol 2001; 195: 451-6.
    • (2001) J Pathol , vol.195 , pp. 451-456
    • Piek, J.M.1    Van Diest, P.J.2    Zweemer, R.P.3
  • 5
    • 33846624310 scopus 로고    scopus 로고
    • Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: Evidence for a causal relationship
    • Kindelberger DW, Lee Y, Miron A, et al., Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: evidence for a causal relationship. Am J Surg Pathol 2007; 31: 161-9 10.1097/01.pas.0000213335.40358.47.
    • (2007) Am J Surg Pathol , vol.31 , pp. 161-169
    • Kindelberger, D.W.1    Lee, Y.2    Miron, A.3
  • 6
    • 79956313481 scopus 로고    scopus 로고
    • Modeling high-grade serous ovarian carcinogenesis from the fallopian tube
    • Karst AM, Levanon K, Drapkin R., Modeling high-grade serous ovarian carcinogenesis from the fallopian tube. Proc Natl Acad Sci USA 2011; 108: 7547-52.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 7547-7552
    • Karst, A.M.1    Levanon, K.2    Drapkin, R.3
  • 7
    • 84891937100 scopus 로고    scopus 로고
    • Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models
    • Perets R, Wyant GA, Muto KW, et al., Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models. Cancer Cell 2013; 24: 751-65.
    • (2013) Cancer Cell , vol.24 , pp. 751-765
    • Perets, R.1    Wyant, G.A.2    Muto, K.W.3
  • 8
    • 80054795415 scopus 로고    scopus 로고
    • Molecular requirements for transformation of fallopian tube epithelial cells into serous carcinoma
    • Jazaeri AA, Bryant JL, Park H, et al., Molecular requirements for transformation of fallopian tube epithelial cells into serous carcinoma. Neoplasia 2011; 13: 899-911.
    • (2011) Neoplasia , vol.13 , pp. 899-911
    • Jazaeri, A.A.1    Bryant, J.L.2    Park, H.3
  • 9
    • 79959838081 scopus 로고    scopus 로고
    • Integrated genomic analyses of ovarian carcinoma
    • Cancer Genome Atlas Network
    • Cancer Genome Atlas Network, Integrated genomic analyses of ovarian carcinoma. Nature 2011; 474: 609-15.
    • (2011) Nature , vol.474 , pp. 609-615
  • 10
    • 10944236962 scopus 로고    scopus 로고
    • Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome
    • Olive KP, Tuveson DA, Ruhe ZC, et al., Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome. Cell 2004; 119: 847-60.
    • (2004) Cell , vol.119 , pp. 847-860
    • Olive, K.P.1    Tuveson, D.A.2    Ruhe, Z.C.3
  • 11
    • 0033053009 scopus 로고    scopus 로고
    • The cell of origin of ovarian epithelial tumors and the ovarian surface epithelium dogma: Does the emperor have no clothes?
    • Dubeau L., The cell of origin of ovarian epithelial tumors and the ovarian surface epithelium dogma: does the emperor have no clothes? Gynecol Oncol 1999; 72: 437-42.
    • (1999) Gynecol Oncol , vol.72 , pp. 437-442
    • Dubeau, L.1
  • 12
    • 77952515048 scopus 로고    scopus 로고
    • Precursor lesions of high-grade serous ovarian carcinoma: Morphological and molecular characteristics
    • Gross AL, Kurman RJ, Vang R, et al., Precursor lesions of high-grade serous ovarian carcinoma: morphological and molecular characteristics. J Oncol 2010; 2010: 126295.
    • (2010) J Oncol , vol.2010 , pp. 126295
    • Gross, A.L.1    Kurman, R.J.2    Vang, R.3
  • 13
    • 0034641864 scopus 로고    scopus 로고
    • Differences in mutant p53 protein stability and functional activity in teniposide-sensitive and -resistant human leukemic CEM cells
    • Morgan SE, Kim R, Wang PC, et al., Differences in mutant p53 protein stability and functional activity in teniposide-sensitive and -resistant human leukemic CEM cells. Oncogene 2000; 19: 5010-9.
    • (2000) Oncogene , vol.19 , pp. 5010-5019
    • Morgan, S.E.1    Kim, R.2    Wang, P.C.3
  • 14
    • 44149121239 scopus 로고    scopus 로고
    • The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss
    • Terzian T, Suh YA, Iwakuma T, et al., The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss. Genes Dev 2008; 22: 1337-44.
    • (2008) Genes Dev , vol.22 , pp. 1337-1344
    • Terzian, T.1    Suh, Y.A.2    Iwakuma, T.3
  • 15
    • 33846187651 scopus 로고    scopus 로고
    • A candidate precursor to serous carcinoma that originates in the distal fallopian tube
    • Lee Y, Miron A, Drapkin R, et al., A candidate precursor to serous carcinoma that originates in the distal fallopian tube. J Pathol 2007; 211: 26-35.
    • (2007) J Pathol , vol.211 , pp. 26-35
    • Lee, Y.1    Miron, A.2    Drapkin, R.3
  • 16
    • 84908340204 scopus 로고    scopus 로고
    • A cautious view of putative precursors of serous carcinomas in the fallopian tubes of BRCA mutation carriers
    • Cass I, Walts AE, Barbuto D, et al., A cautious view of putative precursors of serous carcinomas in the fallopian tubes of BRCA mutation carriers. Gynecol Oncol 2014; 134: 492-7.
    • (2014) Gynecol Oncol , vol.134 , pp. 492-497
    • Cass, I.1    Walts, A.E.2    Barbuto, D.3
  • 17
    • 84866087898 scopus 로고    scopus 로고
    • Primary culture and immortalization of human fallopian tube secretory epithelial cells
    • Karst AM, Drapkin R., Primary culture and immortalization of human fallopian tube secretory epithelial cells. Nat Protocols 2012; 7: 1755-64.
    • (2012) Nat Protocols , vol.7 , pp. 1755-1764
    • Karst, A.M.1    Drapkin, R.2
  • 18
    • 77649185642 scopus 로고    scopus 로고
    • Primary ex vivo cultures of human fallopian tube epithelium as a model for serous ovarian carcinogenesis
    • Levanon K, Ng V, Piao HY, et al., Primary ex vivo cultures of human fallopian tube epithelium as a model for serous ovarian carcinogenesis. Oncogene 2010; 29: 1103-13.
    • (2010) Oncogene , vol.29 , pp. 1103-1113
    • Levanon, K.1    Ng, V.2    Piao, H.Y.3
  • 19
    • 84878597923 scopus 로고    scopus 로고
    • Conditional inactivation of p53 in mouse ovarian surface epithelium does not alter MIS driven Smad2-dominant negative epithelium-lined inclusion cysts or teratomas
    • Quartuccio SM, Lantvit DD, Bosland MC, et al., Conditional inactivation of p53 in mouse ovarian surface epithelium does not alter MIS driven Smad2-dominant negative epithelium-lined inclusion cysts or teratomas. PloS One 2013; 8: e65067.
    • (2013) PloS One , vol.8 , pp. e65067
    • Quartuccio, S.M.1    Lantvit, D.D.2    Bosland, M.C.3
  • 20
    • 84875073562 scopus 로고    scopus 로고
    • Early transformative changes in normal ovarian surface epithelium induced by oxidative stress require Akt upregulation, DNA damage and epithelial-stromal interaction
    • King SM, Quartuccio SM, Vanderhyden BC, et al., Early transformative changes in normal ovarian surface epithelium induced by oxidative stress require Akt upregulation, DNA damage and epithelial-stromal interaction. Carcinogenesis 2013; 34: 1125-33.
    • (2013) Carcinogenesis , vol.34 , pp. 1125-1133
    • King, S.M.1    Quartuccio, S.M.2    Vanderhyden, B.C.3
  • 21
    • 0025040233 scopus 로고
    • Suppression of human colorectal carcinoma cell growth by wild-type p53
    • Baker SJ, Markowitz S, Fearon ER, et al., Suppression of human colorectal carcinoma cell growth by wild-type p53. Science 1990; 249: 912-5.
    • (1990) Science , vol.249 , pp. 912-915
    • Baker, S.J.1    Markowitz, S.2    Fearon, E.R.3
  • 22
    • 84863419728 scopus 로고    scopus 로고
    • TAK1 inhibition promotes apoptosis in KRAS-dependent colon cancers
    • Singh A, Sweeney MF, Yu M, et al., TAK1 inhibition promotes apoptosis in KRAS-dependent colon cancers. Cell 2012; 148: 639-50.
    • (2012) Cell , vol.148 , pp. 639-650
    • Singh, A.1    Sweeney, M.F.2    Yu, M.3
  • 23
    • 50149110590 scopus 로고    scopus 로고
    • Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage
    • Berman SD, Calo E, Landman AS, et al., Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage. Proc Natl Acad Sci USA 2008; 105: 11851-6.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 11851-11856
    • Berman, S.D.1    Calo, E.2    Landman, A.S.3
  • 24
    • 0025341331 scopus 로고
    • New colorimetric cytotoxicity assay for anticancer-drug screening
    • Skehan P, Storeng R, Scudiero D, et al., New colorimetric cytotoxicity assay for anticancer-drug screening. J Natl Cancer Inst 1990; 82: 1107-12.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 1107-1112
    • Skehan, P.1    Storeng, R.2    Scudiero, D.3
  • 25
    • 82355171937 scopus 로고    scopus 로고
    • Nitric oxide suppresses tumor cell migration through N-Myc downstream-regulated gene-1 (NDRG1) expression: Role of chelatable iron
    • Hickok JR, Sahni S, Mikhed Y, et al., Nitric oxide suppresses tumor cell migration through N-Myc downstream-regulated gene-1 (NDRG1) expression: role of chelatable iron. J Biol Chem 2011; 286: 41413-24.
    • (2011) J Biol Chem , vol.286 , pp. 41413-41424
    • Hickok, J.R.1    Sahni, S.2    Mikhed, Y.3
  • 26
    • 0036771713 scopus 로고    scopus 로고
    • Mouse transgenic for murine oviduct-specific glycoprotein promoter-driven simian virus 40 large T-antigen: Tumor formation and its hormonal regulation
    • Miyoshi I, Takahashi K, Kon Y, et al., Mouse transgenic for murine oviduct-specific glycoprotein promoter-driven simian virus 40 large T-antigen: tumor formation and its hormonal regulation. Mol Reprod Dev 2002; 63: 168-76.
    • (2002) Mol Reprod Dev , vol.63 , pp. 168-176
    • Miyoshi, I.1    Takahashi, K.2    Kon, Y.3
  • 27
    • 84902349728 scopus 로고    scopus 로고
    • A genetically engineered ovarian cancer mouse model based on fallopian tube transformation mimics human high-grade serous carcinoma development
    • Sherman-Baust CA, Kuhn E, Valle BL, et al., A genetically engineered ovarian cancer mouse model based on fallopian tube transformation mimics human high-grade serous carcinoma development. J Pathol 2014; 233: 228-37.
    • (2014) J Pathol , vol.233 , pp. 228-237
    • Sherman-Baust, C.A.1    Kuhn, E.2    Valle, B.L.3
  • 28
    • 84880539918 scopus 로고    scopus 로고
    • More targets, more pathways and more clues for mutant p53
    • Garritano S, Inga A, Gemignani F, et al., More targets, more pathways and more clues for mutant p53. Oncogenesis 2013; 2: e54.
    • (2013) Oncogenesis , vol.2 , pp. e54
    • Garritano, S.1    Inga, A.2    Gemignani, F.3
  • 29
    • 34447568277 scopus 로고    scopus 로고
    • Alpha4 chain laminins are widely expressed in renal cell carcinomas and have a de-adhesive function
    • Vainionpaa N, Lehto VP, Tryggvason K, et al., Alpha4 chain laminins are widely expressed in renal cell carcinomas and have a de-adhesive function. Lab Invest 2007; 87: 780-91.
    • (2007) Lab Invest , vol.87 , pp. 780-791
    • Vainionpaa, N.1    Lehto, V.P.2    Tryggvason, K.3
  • 30
    • 84893506505 scopus 로고    scopus 로고
    • A collagen-remodeling gene signature regulated by TGF-beta signaling is associated with metastasis and poor survival in serous ovarian cancer
    • Cheon DJ, Tong Y, Sim MS, et al., A collagen-remodeling gene signature regulated by TGF-beta signaling is associated with metastasis and poor survival in serous ovarian cancer. Clin Cancer Res 2014; 20: 711-23.
    • (2014) Clin Cancer Res , vol.20 , pp. 711-723
    • Cheon, D.J.1    Tong, Y.2    Sim, M.S.3
  • 31
    • 67650996754 scopus 로고    scopus 로고
    • Biomarkers for epithelial-mesenchymal transitions
    • Zeisberg M, Neilson EG., Biomarkers for epithelial-mesenchymal transitions. J Clin Invest 2009; 119: 1429-37.
    • (2009) J Clin Invest , vol.119 , pp. 1429-1437
    • Zeisberg, M.1    Neilson, E.G.2
  • 32
    • 80052183233 scopus 로고    scopus 로고
    • Wild-type p53 controls cell motility and invasion by dual regulation of MET expression
    • Hwang CI, Matoso A, Corney DC, et al., Wild-type p53 controls cell motility and invasion by dual regulation of MET expression. Proc Natl Acad Sci USA 2011; 108: 14240-5.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 14240-14245
    • Hwang, C.I.1    Matoso, A.2    Corney, D.C.3
  • 33
    • 84895072108 scopus 로고    scopus 로고
    • Aurora kinase A mediates epithelial ovarian cancer cell migration and adhesion
    • Do TV, Xiao F, Bickel LE, et al., Aurora kinase A mediates epithelial ovarian cancer cell migration and adhesion. Oncogene 2014; 33: 539-49.
    • (2014) Oncogene , vol.33 , pp. 539-549
    • Do, T.V.1    Xiao, F.2    Bickel, L.E.3
  • 34
    • 84866002291 scopus 로고    scopus 로고
    • The cBio cancer genomics portal: An open platform for exploring multidimensional cancer genomics data
    • Cerami E, Gao J, Dogrusoz U, et al., The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov 2012; 2: 401-4.
    • (2012) Cancer Discov , vol.2 , pp. 401-404
    • Cerami, E.1    Gao, J.2    Dogrusoz, U.3
  • 35
    • 84875740314 scopus 로고    scopus 로고
    • Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
    • Gao J, Aksoy BA, Dogrusoz U, et al., Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci Signal 2013; 6: pl1.
    • (2013) Sci Signal , vol.6 , pp. pl1
    • Gao, J.1    Aksoy, B.A.2    Dogrusoz, U.3
  • 36
    • 42949138321 scopus 로고    scopus 로고
    • A candidate precursor to pelvic serous cancer (p53 signature) and its prevalence in ovaries and fallopian tubes from women with BRCA mutations
    • Folkins AK, Jarboe EA, Saleemuddin A, et al., A candidate precursor to pelvic serous cancer (p53 signature) and its prevalence in ovaries and fallopian tubes from women with BRCA mutations. Gynecol Oncol 2008; 109: 168-73.
    • (2008) Gynecol Oncol , vol.109 , pp. 168-173
    • Folkins, A.K.1    Jarboe, E.A.2    Saleemuddin, A.3
  • 37
    • 84865140569 scopus 로고    scopus 로고
    • Perturbation of Rb, p53 and Brca1 or Brca2 cooperate in inducing metastatic serous epithelial ovarian cancer
    • Szabova L, Yin C, Bupp S, et al., Perturbation of Rb, p53 and Brca1 or Brca2 cooperate in inducing metastatic serous epithelial ovarian cancer. Cancer Res 2012; 72: 4141-53.
    • (2012) Cancer Res , vol.72 , pp. 4141-4153
    • Szabova, L.1    Yin, C.2    Bupp, S.3
  • 38
    • 33749482498 scopus 로고    scopus 로고
    • A mouse model for the molecular characterization of brca1-associated ovarian carcinoma
    • Xing D, Orsulic S., A mouse model for the molecular characterization of brca1-associated ovarian carcinoma. Cancer Res 2006; 66: 8949-53.
    • (2006) Cancer Res , vol.66 , pp. 8949-8953
    • Xing, D.1    Orsulic, S.2
  • 39
    • 0037444396 scopus 로고    scopus 로고
    • Female mice chimeric for expression of the simian virus 40 TAg under control of the MISIIR promoter develop epithelial ovarian cancer
    • Connolly DC, Bao R, Nikitin AY, et al., Female mice chimeric for expression of the simian virus 40 TAg under control of the MISIIR promoter develop epithelial ovarian cancer. Cancer Res 2003; 63: 1389-97.
    • (2003) Cancer Res , vol.63 , pp. 1389-1397
    • Connolly, D.C.1    Bao, R.2    Nikitin, A.Y.3
  • 40
    • 84875205987 scopus 로고    scopus 로고
    • Type i to type II ovarian carcinoma progression: Mutant Trp53 or Pik3ca confers a more aggressive tumor phenotype in a mouse model of ovarian cancer
    • Wu R, Baker SJ, Hu TC, et al., Type I to type II ovarian carcinoma progression: mutant Trp53 or Pik3ca confers a more aggressive tumor phenotype in a mouse model of ovarian cancer. Am J Pathol 2013; 182: 1391-9.
    • (2013) Am J Pathol , vol.182 , pp. 1391-1399
    • Wu, R.1    Baker, S.J.2    Hu, T.C.3
  • 41
    • 84863230370 scopus 로고    scopus 로고
    • High-grade serous ovarian cancer arises from fallopian tube in a mouse model
    • Kim J, Coffey DM, Creighton CJ, et al., High-grade serous ovarian cancer arises from fallopian tube in a mouse model. Proc Natl Acad Sci USA 2012; 109: 3921-6.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 3921-3926
    • Kim, J.1    Coffey, D.M.2    Creighton, C.J.3
  • 42
    • 15544362735 scopus 로고    scopus 로고
    • Snail and Slug are major determinants of ovarian cancer invasiveness at the transcription level
    • K A
    • Kurrey NK, K A, Bapat SA., Snail and Slug are major determinants of ovarian cancer invasiveness at the transcription level. Gynecol Oncol 2005; 97: 155-65.
    • (2005) Gynecol Oncol , vol.97 , pp. 155-165
    • Kurrey, N.K.1    Bapat, S.A.2
  • 43
    • 84899576175 scopus 로고    scopus 로고
    • Expression profiles of epithelial-mesenchymal transition-associated proteins in epithelial ovarian carcinoma
    • Kim MK, Kim MA, Kim H, et al., Expression profiles of epithelial-mesenchymal transition-associated proteins in epithelial ovarian carcinoma. BioMed Res Int 2014; 2014: 495754.
    • (2014) BioMed Res Int , vol.2014 , pp. 495754
    • Kim, M.K.1    Kim, M.A.2    Kim, H.3
  • 44
    • 27744547091 scopus 로고    scopus 로고
    • Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma
    • Wu WS, Heinrichs S, Xu D, et al., Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma. Cell 2005; 123: 641-53.
    • (2005) Cell , vol.123 , pp. 641-653
    • Wu, W.S.1    Heinrichs, S.2    Xu, D.3
  • 45
    • 84908090381 scopus 로고    scopus 로고
    • Cooperative actions of p21WAF1 and p53 induce Slug protein degradation and suppress cell invasion
    • Kim J, Bae S, An S, et al., Cooperative actions of p21WAF1 and p53 induce Slug protein degradation and suppress cell invasion. EMBO Rep 2014; 15: 1062-8.
    • (2014) EMBO Rep , vol.15 , pp. 1062-1068
    • Kim, J.1    Bae, S.2    An, S.3
  • 46
    • 67349166210 scopus 로고    scopus 로고
    • P53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug
    • Wang SP, Wang WL, Chang YL, et al., p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug. Nat Cell Biol 2009; 11: 694-704.
    • (2009) Nat Cell Biol , vol.11 , pp. 694-704
    • Wang, S.P.1    Wang, W.L.2    Chang, Y.L.3
  • 47
    • 72249100428 scopus 로고    scopus 로고
    • Mutant p53 drives invasion by promoting integrin recycling
    • Muller PA, Caswell PT, Doyle B, et al., Mutant p53 drives invasion by promoting integrin recycling. Cell 2009; 139: 1327-41.
    • (2009) Cell , vol.139 , pp. 1327-1341
    • Muller, P.A.1    Caswell, P.T.2    Doyle, B.3
  • 48
    • 84869121043 scopus 로고    scopus 로고
    • Various p53 mutant proteins differently regulate the Ras circuit to induce a cancer-related gene signature
    • Solomon H, Buganim Y, Kogan-Sakin I, et al., Various p53 mutant proteins differently regulate the Ras circuit to induce a cancer-related gene signature. J Cell Sci 2012; 125: 3144-52.
    • (2012) J Cell Sci , vol.125 , pp. 3144-3152
    • Solomon, H.1    Buganim, Y.2    Kogan-Sakin, I.3
  • 49
    • 78649908015 scopus 로고    scopus 로고
    • Aurora-A overexpression and aneuploidy predict poor outcome in serous ovarian carcinoma
    • Lassus H, Staff S, Leminen A, et al., Aurora-A overexpression and aneuploidy predict poor outcome in serous ovarian carcinoma. Gynecol Oncol 2011; 120: 11-7.
    • (2011) Gynecol Oncol , vol.120 , pp. 11-17
    • Lassus, H.1    Staff, S.2    Leminen, A.3
  • 50
    • 84866749750 scopus 로고    scopus 로고
    • P53 negatively regulates Aurora A via both transcriptional and posttranslational regulation
    • Wu CC, Yang TY, Yu CT, et al., p53 negatively regulates Aurora A via both transcriptional and posttranslational regulation. Cell Cycle 2012; 11: 3433-42.
    • (2012) Cell Cycle , vol.11 , pp. 3433-3442
    • Wu, C.C.1    Yang, T.Y.2    Yu, C.T.3


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