Artesunate induces apoptosis and inhibits growth of Eca109 and Ec9706 human esophageal cancer cell lines in vitro and in vivo

Molecular Medicine Reports

Volumn 12, Issue 1, 2015, Pages 1465-1472

  Liu, Liang ^a   Zuo, Lian Fu ^a   Zuo, Jing ^a   Wang, Jing ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Artesunate; Cell division cycle 25 A; Esophageal carcinoma; Flow cytometry; Mitochondrial membrane potential

Indexed keywords

ARTESUNATE; CASPASE 3; CDC25A PROTEIN; CISPLATIN; PROTEIN; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG; ARTEMISININ DERIVATIVE; CDC25A PROTEIN, HUMAN; PROTEIN TYROSINE PHOSPHATASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL GROWTH; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ESOPHAGEAL CANCER CELL LINE; ESOPHAGUS CARCINOMA; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INVESTIGATIVE PROCEDURES; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; NUDE MOUSE; PROTEIN EXPRESSION; TUMOR REGRESSION; TUMOR XENOGRAFT; UPREGULATION; ANIMAL; BIOSYNTHESIS; CELL PROLIFERATION; DRUG EFFECTS; DRUG SCREENING; ESOPHAGEAL NEOPLASMS; GENE EXPRESSION REGULATION; GENETICS; PATHOLOGY; TUMOR CELL LINE;

MUS MUSCULUS;

ANIMALS; APOPTOSIS; ARTEMISININS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CDC25 PHOSPHATASES; CELL LINE, TUMOR; CELL PROLIFERATION; CISPLATIN; ESOPHAGEAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; PROTO-ONCOGENE PROTEINS C-BCL-2; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84926653441     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3517     Document Type: Article

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