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Volumn 56, Issue 2, 2014, Pages 119-126

Chitosan exerts anticancer activity through induction of apoptosis and cell cycle arrest in oral cancer cells

Author keywords

Apoptosis; Cell cycle; Chitosan; Electron microscopy; Oral cancer; Proliferation

Indexed keywords

ANTINEOPLASTIC AGENT; CHITOSAN;

EID: 84973423150     PISSN: 13434934     EISSN: 18804926     Source Type: Journal    
DOI: 10.2334/josnusd.56.119     Document Type: Article
Times cited : (111)

References (25)
  • 2
    • 84896368178 scopus 로고    scopus 로고
    • Cytotoxic effects of chitosan against oral cancer cell lines is molecular-weight-dependent and celltype-specific
    • Wimardhani YS, Suniarti DF, Freisleben HJ, Wanandi SI, Ikeda MA (2012) Cytotoxic effects of chitosan against oral cancer cell lines is molecular-weight-dependent and celltype-specific. Int J Oral Res 3, e1
    • (2012) Int J Oral Res , vol.3
    • Wimardhani, Y.S.1    Suniarti, D.F.2    Freisleben, H.J.3    Wanandi, S.I.4    Ikeda, M.A.5
  • 4
    • 7444237728 scopus 로고    scopus 로고
    • Proapoptotic effect of a dietary supplement: Water soluble chitosan activates caspase-8 and modulating death receptor expression
    • Takimoto H, Hasegawa M, Yagi K, Nakamura T, Sakaeda T, Hirai M (2004) Proapoptotic effect of a dietary supplement: water soluble chitosan activates caspase-8 and modulating death receptor expression. Drug Metab Pharmacokinet 19, 76-82
    • (2004) Drug Metab Pharmacokinet , vol.19 , pp. 76-82
    • Takimoto, H.1    Hasegawa, M.2    Yagi, K.3    Nakamura, T.4    Sakaeda, T.5    Hirai, M.6
  • 5
    • 26244467518 scopus 로고    scopus 로고
    • In vitro effects of chitosan nanoparticles on proliferation of human gastric carcinoma cell line MGC803 cells
    • Qi LF, Xu ZR, Li Y, Jiang X, Han XY (2005) In vitro effects of chitosan nanoparticles on proliferation of human gastric carcinoma cell line MGC803 cells. World J Gastroenterol 11, 5136-5141
    • (2005) World J Gastroenterol , vol.11 , pp. 5136-5141
    • Qi, L.F.1    Xu, Z.R.2    Li, Y.3    Jiang, X.4    Han, X.Y.5
  • 6
    • 34047097273 scopus 로고    scopus 로고
    • Chitosan prevents the development of AOM-induced aberrant crypt foci in mice and suppressed the proliferation of AGS cells by inhibiting DNA synthesis
    • Lin SY, Chan HY, Shen FH, Chen MH, Wang YJ, Yu CK (2007) Chitosan prevents the development of AOM-induced aberrant crypt foci in mice and suppressed the proliferation of AGS cells by inhibiting DNA synthesis. J Cell Biochem 100, 1573-1580
    • (2007) J Cell Biochem , vol.100 , pp. 1573-1580
    • Lin, S.Y.1    Chan, H.Y.2    Shen, F.H.3    Chen, M.H.4    Wang, Y.J.5    Yu, C.K.6
  • 7
    • 0026560020 scopus 로고
    • Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumorsuppressor genes
    • Sakai E, Tsuchida N (1992) Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumorsuppressor genes. Oncogene 7, 927-933
    • (1992) Oncogene , vol.7 , pp. 927-933
    • Sakai, E.1    Tsuchida, N.2
  • 8
    • 48649099197 scopus 로고    scopus 로고
    • Clinical and biological significance of tissue transglutaminase in ovarian carcinoma
    • Hwang JY, Mangala LS, Fok JY, Lin YG, Merritt WM, Spannuth WA et al. (2008) Clinical and biological significance of tissue transglutaminase in ovarian carcinoma. Cancer Res 68, 5849-5858
    • (2008) Cancer Res , vol.68 , pp. 5849-5858
    • Hwang, J.Y.1    Mangala, L.S.2    Fok, J.Y.3    Lin, Y.G.4    Merritt, W.M.5    Spannuth, W.A.6
  • 9
    • 77955889102 scopus 로고    scopus 로고
    • Analysis of cellular DNA content by flow and laser scanning cytometry
    • Darzynkiewicz Z, Halicka HD, Zhao H (2010) Analysis of cellular DNA content by flow and laser scanning cytometry. Adv Exp Med Biol 676, 137-147
    • (2010) Adv Exp Med Biol , vol.676 , pp. 137-147
    • Darzynkiewicz, Z.1    Halicka, H.D.2    Zhao, H.3
  • 11
    • 1242314681 scopus 로고    scopus 로고
    • Uptake and cytotoxicity of chitosan molecules and nanoparticles: Effects of molecular weight and degree of deacetylation
    • Huang M, Khor E, Lim LY (2004) Uptake and cytotoxicity of chitosan molecules and nanoparticles: effects of molecular weight and degree of deacetylation. Pharm Res 21, 344-353
    • (2004) Pharm Res , vol.21 , pp. 344-353
    • Huang, M.1    Khor, E.2    Lim, L.Y.3
  • 12
    • 77953546375 scopus 로고    scopus 로고
    • Anti-tumor activity of N-trimethyl chitosan-encapsulated camptothecin in a mouse melanoma model
    • Liu XP, Zhou ST, Li XY, Chen XC, Zhao X, Qian ZY et al. (2010) Anti-tumor activity of N-trimethyl chitosan-encapsulated camptothecin in a mouse melanoma model. J Exp Clin Cancer Res 29, 76
    • (2010) J Exp Clin Cancer Res , vol.29 , pp. 76
    • Liu, X.P.1    Zhou, S.T.2    Li, X.Y.3    Chen, X.C.4    Zhao, X.5    Qian, Z.Y.6
  • 13
    • 0030309474 scopus 로고    scopus 로고
    • Chitin biotechnology applications
    • Hirano S (1996) Chitin biotechnology applications. Biotechnol Annu Rev 2, 237-258
    • (1996) Biotechnol Annu Rev , vol.2 , pp. 237-258
    • Hirano, S.1
  • 14
    • 0035889837 scopus 로고    scopus 로고
    • The effect of chitin and chitosan on the proliferation of human skin fibroblasts and keratinocytes in vitro
    • Howling GI, Dettmar PW, Goddard PA, Hampson FC, Dornish M, Wood EJ (2001) The effect of chitin and chitosan on the proliferation of human skin fibroblasts and keratinocytes in vitro. Biomaterials 22, 2959-2966
    • (2001) Biomaterials , vol.22 , pp. 2959-2966
    • Howling, G.I.1    Dettmar, P.W.2    Goddard, P.A.3    Hampson, F.C.4    Dornish, M.5    Wood, E.J.6
  • 15
    • 77955291582 scopus 로고    scopus 로고
    • Chitosan modification and pharmaceutical/biomedical applications
    • Zhang J, Xia W, Liu P, Cheng Q, Tahirou T, Gu W et al. (2010) Chitosan modification and pharmaceutical/biomedical applications. Mar Drugs 8, 1962-1987
    • (2010) Mar Drugs , vol.8 , pp. 1962-1987
    • Zhang, J.1    Xia, W.2    Liu, P.3    Cheng, Q.4    Tahirou, T.5    Gu, W.6
  • 16
    • 75149119369 scopus 로고    scopus 로고
    • Molecular-weightdependent toxic effects of chitosans on the human keratinocyte cell line HaCaT
    • Wiegand C, Winter D, Hipler UC (2010) Molecular-weightdependent toxic effects of chitosans on the human keratinocyte cell line HaCaT. Skin Pharmacol Physiol 23, 164-170
    • (2010) Skin Pharmacol Physiol , vol.23 , pp. 164-170
    • Wiegand, C.1    Winter, D.2    Hipler, U.C.3
  • 17
    • 70449718715 scopus 로고    scopus 로고
    • Association of caspase-8 mutation with chemoresistance to cisplatin in HOC313 head and neck squamous cell carcinoma cells
    • Liu J, Uematsu H, Tsuchida N, Ikeda MA (2009) Association of caspase-8 mutation with chemoresistance to cisplatin in HOC313 head and neck squamous cell carcinoma cells. Biochem Biophys Res Commun 390, 989-994
    • (2009) Biochem Biophys Res Commun , vol.390 , pp. 989-994
    • Liu, J.1    Uematsu, H.2    Tsuchida, N.3    Ikeda, M.A.4
  • 18
    • 0035072953 scopus 로고    scopus 로고
    • Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I
    • Coleman ML, Sahai EA, Yeo M, Bosch M, Dewar A, Olson MF (2001) Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I. Nat Cell Biol 3, 339-345
    • (2001) Nat Cell Biol , vol.3 , pp. 339-345
    • Coleman, M.L.1    Sahai, E.A.2    Yeo, M.3    Bosch, M.4    Dewar, A.5    Olson, M.F.6
  • 19
    • 4043173966 scopus 로고    scopus 로고
    • Effect of extracts of trichosanthes root tubers on HepA-H cells and HeLa cells
    • Dou CM, Li JC (2004) Effect of extracts of trichosanthes root tubers on HepA-H cells and HeLa cells. World J Gastroenterol 10, 2091-2094
    • (2004) World J Gastroenterol , vol.10 , pp. 2091-2094
    • Dou, C.M.1    Li, J.C.2
  • 20
    • 0038052805 scopus 로고    scopus 로고
    • The cell cycle: A review of regulation, deregulation and therapeutic targets in cancer
    • Vermeulen K, Van Bockstaele DR, Berneman ZN (2003) The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer. Cell Prolif 36, 131-149
    • (2003) Cell Prolif , vol.36 , pp. 131-149
    • Vermeulen, K.1    Van Bockstaele, D.R.2    Berneman, Z.N.3
  • 21
    • 0035545996 scopus 로고    scopus 로고
    • Mammalian G1-and S-phase checkpoints in response to DNA damage
    • Bartek J, Lukas J (2001) Mammalian G1-and S-phase checkpoints in response to DNA damage. Curr Opin Cell Biol 13, 738-747
    • (2001) Curr Opin Cell Biol , vol.13 , pp. 738-747
    • Bartek, J.1    Lukas, J.2
  • 22
    • 0028168242 scopus 로고
    • P15INK4B is a potential effector of TGF-β-induced cell cycle arrest
    • Hannon GJ, Beach D (1994) p15INK4B is a potential effector of TGF-β-induced cell cycle arrest. Nature 371, 257-261
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 23
    • 0029153609 scopus 로고
    • Kip/ Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β
    • Reynisdóttir I, Polyak K, Iavarone A, Massagué J (1995) Kip/ Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β. Genes Dev 9, 1831-1845
    • (1995) Genes Dev , vol.9 , pp. 1831-1845
    • Reynisdóttir, I.1    Polyak, K.2    Iavarone, A.3    Massagué, J.4
  • 24
    • 0035848819 scopus 로고    scopus 로고
    • The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis
    • Falck J, Mailand N, Syljuåsen RG, Bartek J, Lukas J (2001) The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature 410, 842-847
    • (2001) Nature , vol.410 , pp. 842-847
    • Falck, J.1    Mailand, N.2    Syljuåsen, R.G.3    Bartek, J.4    Lukas, J.5
  • 25
    • 77956629716 scopus 로고    scopus 로고
    • Transforming growth factorbeta induces senescence in hepatocellular carcinoma cells and inhibits tumor growth
    • Senturk S, Mumcuoglu M, Gursoy-Yuzugullu O, Cingoz B, Akcali KC, Ozturk M (2010) Transforming growth factorbeta induces senescence in hepatocellular carcinoma cells and inhibits tumor growth. Hepatology 52, 966-974.
    • (2010) Hepatology , vol.52 , pp. 966-974
    • Senturk, S.1    Mumcuoglu, M.2    Gursoy-Yuzugullu, O.3    Cingoz, B.4    Akcali, K.C.5    Ozturk, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.