Combined loss of the GATA4 and GATA6 transcription factors in male mice disrupts testicular development and confers adrenal-like function in the testes

Endocrinology (United States)

Volumn 156, Issue 5, 2015, Pages 1873-1886

  Padua, Maria B ^a   Jiang, Tianyu ^a   Morse, Deborah A ^a,b   Fox, Shawna C ^a   Hatch, Heather M ^a   Tevosian, Sergei G ^a  

^a University of Florida   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; ALDOSTERONE SYNTHASE; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYTOCHROME P450 CYP11B1; DOUBLESEX AND MAB 3-RELATED TRANSCRIPTION FACTOR 1; ENZYME; MCR2 ENZYME; STEROID 17ALPHA MONOOXYGENASE; TESTOSTERONE 17BETA DEHYDROGENASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR GATA 6; UNCLASSIFIED DRUG; CYP21A1 PROTEIN, MOUSE; DMRT1 PROTEIN; GATA4 PROTEIN, MOUSE; GATA6 PROTEIN, MOUSE; HYDROXYSTEROID DEHYDROGENASE; MESSENGER RNA; MUELLERIAN INHIBITING FACTOR; PHOSPHOPROTEIN; STEROID 11BETA MONOOXYGENASE; STEROID 21 MONOOXYGENASE; STEROIDOGENIC ACUTE REGULATORY PROTEIN;

ADRENAL FUNCTION; ANIMAL CELL; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; EMBRYO DEVELOPMENT; GENE DELETION; GENE OVEREXPRESSION; IMMUNOHISTOCHEMISTRY; LEYDIG CELL; MALE; MOUSE; MUTANT; NONHUMAN; PERINATAL PERIOD; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; SERTOLI CELL; SPERMATOGONIUM; TESTIS DEVELOPMENT; TESTOSTERONE SYNTHESIS; UPREGULATION; ADRENAL GLAND; ANIMAL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; TESTIS;

17-HYDROXYSTEROID DEHYDROGENASES; 3-HYDROXYSTEROID DEHYDROGENASES; ADRENAL GLANDS; ANIMALS; ANTI-MULLERIAN HORMONE; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; CYTOCHROME P-450 CYP11B2; GATA4 TRANSCRIPTION FACTOR; GATA6 TRANSCRIPTION FACTOR; GENE DELETION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MALE; MICE; PHOSPHOPROTEINS; RNA, MESSENGER; STEROID 11-BETA-HYDROXYLASE; STEROID 21-HYDROXYLASE; TESTIS; TRANSCRIPTION FACTORS;

EID: 84926621150     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2014-1907     Document Type: Article

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