Immunolocalization of murine type VI 3β-hydroxysteroid dehydrogenase in the adrenal gland, testis, skin, and placenta

Molecular and Cellular Endocrinology

Volumn 382, Issue 1, 2014, Pages 131-138

  Yamamura, Koki ^a   Doi, Masao ^a   Hayashi, Hida ^a   Ota, Takumi ^a   Murai, Iori ^a   Hotta, Yunhong ^a   Komatsu, Rie ^a   Okamura, Hitoshi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

3 Hydroxysteroid dehydrogenase isomerase; Hsd3b6; Steroidogenesis

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; 3BETA HYDROXYSTEROID DEHYDROGENASE 6; ALDOSTERONE; CORTICOSTERONE; HORMONE ANTIBODY; PROGESTERONE; STEROID HORMONE; TESTOSTERONE; UNCLASSIFIED DRUG;

ADRENAL CORTEX CELL; ADRENAL GLAND; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; CELL TYPE; CONTROLLED STUDY; EMBRYO CELL; ENZYME ACTIVITY; FEMALE; GONAD; HORMONE ACTION; HORMONE SYNTHESIS; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; IMMUNOREACTIVITY; LEYDIG CELL; MALE; MOUSE; NIDATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OVARY; PLACENTA; PRIORITY JOURNAL; PROGESTERONE SYNTHESIS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REPRODUCTION; SEBACEOUS GLAND; SKIN; SKIN FUNCTION; TESTIS; TESTOSTERONE SYNTHESIS; TISSUE DISTRIBUTION; TROPHOBLAST; ZONA FASCICULATA; ZONA GLOMERULOSA;

3Β-HYDROXYSTEROID DEHYDROGENASE/ISOMERASE; HSD3B6; STEROIDOGENESIS;

17-HYDROXYSTEROID DEHYDROGENASES; ADRENAL GLANDS; ANIMALS; ANTIBODY SPECIFICITY; BIOSYNTHETIC PATHWAYS; FEMALE; GENE EXPRESSION PROFILING; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; OVARY; PLACENTA; PREGNANCY; SKIN; STEROIDS; TESTIS; TISSUE DISTRIBUTION;

EID: 84885202566     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2013.09.014     Document Type: Article

References (25)

1. Abbaszade I.G., Clarke T.R., Park C.H., Payne A.H. The mouse 3 beta-hydroxysteroid dehydrogenase multigene family includes two functionally distinct groups of proteins. Mol. Endocrinol. 1995, 9:1214-1222.
2. Abbaszade I.G., Arensburg J., Park C.H., Kasa-Vubu J.Z., Orly J., Payne A.H. Isolation of a new mouse 3beta-hydroxysteroid dehydrogenase isoform, 3beta-HSD VI, expressed during early pregnancy. Endocrinology 1997, 138:1392-1399.
3. Arensburg J., Payne A.H., Orly J. Expression of steroidogenic genes in maternal and extraembryonic cells during early pregnancy in mice. Endocrinology 1999, 140:5220-5232.
4. Bain P.A., Yoo M., Clarke T., Hammond S.H., Payne A.H. Multiple forms of mouse 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase and differential expression in gonads, adrenal glands, liver, and kidneys of both sexes. Proc Natl Acad Sci USA 1991, 88:8870-8874.
5. Clarke T.R., Bain P.A., Greco T.L., Payne A.H. A novel mouse kidney 3 beta-hydroxysteroid dehydrogenase complementary DNA encodes a 3-ketosteroid reductase instead of a 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase. Mol. Endocrinol. 1993, 7:1569-1578.
6. Courchay G., Boyera N., Bernard B.A., Mahe Y. Messenger RNA expression of steroidogenesis enzyme subtypes in the human pilosebaceous unit. Skin Pharmacol 1996, 9:169-176.
7. Doi M., Okano T., Yujnovsky I., Sassone-Corsi P., Fukada Y. Negative control of circadian clock regulator E4BP4 by casein kinase Iepsilon-mediated phosphorylation. Curr. Biol. 2004, 14:975-980.
8. Doi M., Takahashi Y., Komatsu R., Yamazaki F., Yamada H., Haraguchi S., Emoto N., Okuno Y., Tsujimoto G., Kanematsu A., Ogawa O., Todo T., Tsutsui K., van der Horst G.T.J., Okamura H. Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6. Nat. Med. 2010, 16:67-74.
9. Dumont M., Luu-The V., Dupont E., Pelletier G., Labrie F. Characterization, expression, and immunohistochemical localization of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase in human skin. J. Invest. Dermatol. 1992, 99:415-421.
10. Hoffmann R., Rot A., Niiyama S., Billich A. Steroid sulfatase in the human hair follicle concentrates in the dermal papilla. J. Invest. Dermatol. 2001, 117:1342-1348.
11. Hou Y., Zhang H., Miranda L., Lin S. Serious overestimation in quantitative PCR by circular (supercoiled) plasmid standard: microalgal pcna as the model gene. PLoS One 2010, 5:e9545.
12. Labrie F., Luu-The V., Labrie C., Pelletier G., El-Alfy M. Intracrinology and the skin. Hormone Res. 2000, 54:218-229.
13. Lorence M.C., Murry B.A., Trant J.M., Mason J.I. Human 3 beta-hydroxysteroid dehydrogenase/delta 5-4isomerase from placenta: expression in nonsteroidogenic cells of a protein that catalyzes the dehydrogenation/isomerization of C21 and C19 steroids. Endocrinology 1990, 126:2493-2498.
14. Luu-The V., Labrie F. The intracrine sex steroid biosynthesis pathways. Prog. Brain Res. 2010, 181:177-192.
15. Luu-The V., Sugimoto Y., Puy L., Labrie Y., Lopez Solache I., Singh M., Labrie F. Characterization, expression, and immunohistochemical localization of 5 alpha-reductase in human skin. J. Invest. Dermatol. 1994, 102:221-226.
16. Mason J.I., Ushijima K., Doody K.M., Nagai K., Naville D., Head J.R., Milewich L., Rainey W.E., Ralph M.M. Regulation of expression of the 3 beta-hydroxysteroid dehydrogenases of human placenta and fetal adrenal. J. Steroid Biochem. Mol. Biol. 1993, 47:151-159.
17. Ota T., Fustin J.M., Yamada H., Doi M., Okamura H. Circadian clock signals in the adrenal cortex. Mol. Cell. Endocrinol. 2012, 349:30-37.
18. Payne A.H., Hales D.B. Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones. Endocr. Rev. 2004, 25:947-970.
19. Peng L., Arensburg J., Orly J., Payne A.H. The murine 3beta-hydroxysteroid dehydrogenase (3beta-HSD) gene family: a postulated role for 3beta-HSD VI during early pregnancy. Mol. Cell. Endocrinol. 2002, 187:213-221.
20. Rheaume E., Lachance Y., Zhao H.F., Breton N., Dumont M., de Launoit Y., Trudel C., Luu-The V., Simard J., Labrie F. Structure and expression of a new complementary DNA encoding the almost exclusive 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase in human adrenals and gonads. Mol. Endocrinol. 1991, 5:1147-1157.
21. Riley S.C., Dupont E., Walton J.C., Luu-The V., Labrie F., Pelletier G., Challis J.R. Immunohistochemical localization of 3 beta-hydroxy-5-ene-steroid dehydrogenase/delta 5 - delta 4 isomerase in human placenta and fetal membranes throughout gestation. J. Clin. Endocrinol. Metab. 1992, 75:956-961.
22. Sawaya M.E., Penneys N.S. Immunohistochemical distribution of aromatase and 3B-hydroxysteroid dehydrogenase in human hair follicle and sebaceous gland. J. Cutan. Pathol. 1992, 19:309-314.
23. Simard J., Ricketts M.L., Gingras S., Soucy P., Feltus F.A., Melner M.H. Molecular biology of the 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase gene family. Endocr. Rev. 2005, 26:525-582.
24. Simpton N.B., Cunliffe W.J., Hodgins M.B. The relationship between the vitro activity of 3 beta-hydroxysteroid dehydrogenase delta 4-5-isomerase in human sebaceous glands and their secretary activity in vivo. J. Invest. Dermatol. 1983, 81:139-144.
25. Tanaka R., Tainaka M., Ota T., Mizuguchi N., Kato H., Urabe S., Chen Y., Fustin J.M., Yamaguchi Y., Doi M., Hamada S., Okamura H. Accurate determination of S-phase fraction in proliferative cells by dual fluorescence and peroxidase immunohistochemistry with 5-bromo-2'-deoxyuridine (BrdU) and Ki67 antibodies. J. Histochem. Cytochem. 2011, 59:791-798.