Fetal development of Leydig cell activity in the mouse is independent of pituitary gonadotroph function

Endocrinology

Volumn 139, Issue 3, 1998, Pages 1141-1146

  O'Shaughnessy, P J ^a   Baker, P ^a   Sohnius, U ^b   Haavisto, A M ^c   Charlton, H M ^b   Huhtaniemi, I ^c  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF TURKU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; GONADOTROPIN; LUTEINIZING HORMONE; STEROID 17ALPHA MONOOXYGENASE; TESTOSTERONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ENZYME ACTIVITY; FETUS; FETUS DEVELOPMENT; GONADOTROPIN BLOOD LEVEL; HYPOPHYSIS FUNCTION; LEYDIG CELL; LUTEINIZING HORMONE BLOOD LEVEL; LUTEINIZING HORMONE RELEASE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TESTOSTERONE BLOOD LEVEL;

EID: 0031796489     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.139.3.5788     Document Type: Article

References (45)

1. Jost A 1970 Hormonal factors in the sex differentiation of the mammalian foetus. Philos. Trans R Soc Lond Biol 259:119-130
2. Josso N, Picard JY 1986 Anti-mullerian hormone. Physiol Rev 66:1038-1090
3. Gondos, B 1980 Development and differentiation of the testis and male reproductive tract. In: Steinberger A, Steinberger B (eds) Testicular Development, Structure and Function. Raven Press, New York, pp 3-20
4. Huhtaniemi IT, Nozu K, Warren DW, Dufau ML, Catt KJ 1982 Acquisition of regulatory mechanisms for gonadotropin receptors and steroidogenesis in the maturing rat testis. Endocrinology 111:1711-1720
5. Tapanainen J, Kuopio T, Pelliniemi LJ, Huhtaniemi I 1984 Rat testicular endogenous steroids and number of Leydig cells between the fetal period and sexual maturity. Biol Reprod 31:1027-1035
6. Gupta C, Singh M 1996 Stimulation of epidermal growth factor gene expression during the fetal mouse reproductive tract differentiation: role of androgen and its receptor. Endocrinology 137:705-711
7. Burrows HL, Birkmeier TS, Seasholtz AF, Camper SA 1996 Targeted ablation of cells in the pituitary primordia of transgenic mice. Mol Endocrinol 10:1467-1477
8. Schwanzel-Fukunda M, Pfaff DW 1989 Origin of luteinizing hormone releasing hormone neurons. Nature 338:161-164
9. Japon MA, Rubinstein M, Low MJ 1994 In situ hybridization analysis of anterior pituitary hormone gene expression during fetal mouse development. J Histochem Cytochem 42:1117-1125
10. George FW, Catt KJ, Neaves WB, Wilson JD 1978 Studies on the regulation of testosterone synthesis in the fetal rabbit testis. Endocrinology 102:665-673
11. Huhtaniemi I 1995 Molecular aspects of the ontogeny of the pituitary-gonadal axis. Reprod Fertil Dev 7:1025-1035
12. El-Ghani F, Zhang F-P, Pakarinen P, Rannikko A, Huhtaniemi I, Gonadotropin-independent regulation of steroidogenesis in the rat fetal testis. Biol Reprod, in press
13. Cattanach BM, Iddon CA, Charlton HM, Chiappa SA, Fink G 1977 Gonadotrophin releasing hormone deficiency in a mutant mouse with hypogonadism. Nature 269:338-340
14. Kendall SK, Samuelson LC, Saunders TL, Wood RI, Camper SA 1995 Targeted disruption of the pituitary glycoprotein hormone α-subunit produces hypogonadal and hypothyroid mice. Genes Dev 9:2007-201
15. Lang J 1995 Assay for deletion in GnRH (hpg) locus using PCR. Mouse Genet 89:857
16. Haavisto A-M, Pettersson K, Bergendahl M, Perheentupa A, Roser J, Huhtaniemi I 1993 A supersensitive immunofluorometric assay for rat luteinizing hormone. Endocrinology 132:1687-11691
17. O'Shaughnessy PJ, Sheffield JW 1990 Effect of testosterone on testicular steroidogenesis in the hypogonadal (hpg) mouse. J Steroid Biochem 35:729-734
18. O'Shaughnessy PJ, Murphy L 1993 Cytochrome P-450 17α-hydroxylase protein and mRNA in the testis of the testicular feminized (Tfm) mouse. J Mol Endocrinol 11:77-82
19. O'Shaughnessy PJ, Marsh P, Dudley K 1994 Follicle-stimulating hormone receptor mRNA in the mouse ovary during post-natal development in the normal mouse and in the adult hypogonadal (hpg) mouse: structure of alternate transcripts. 101:197-201
20. O'Shaughnessy PJ, McLelland D, McBride MW 1497 Regulation of luteinizing hormone-receptor and follicle-stimulating hormone receptor messenger ribonucleic acid levels during development in the neonatal mouse ovary. Biol Reprod 57:602-608
21. 4 isomerase and differential expression in gonads, adrenal glands, liver, and kidneys of both sexes. Proc Natl Acad Sci USA 88:8870-8874
22. O'Shaughnessy PJ, Mannan MA 1994 Development of cytochrome P-450 side chain cleavage mRNA levels in neonatal ovaries of normal and hypogonadal (hpg) mice. Mol Cell Endocrinol 104:133-138
23. Youngblood GL, Payne AH 1992 Isolation and characterization of the mouse P450 17α-hydroxylase C17-20 lyase gene (cyp17): transcriptional regulation of the gene by cyclic adenosine 3′,5′-monophosphate in MA10 Leydig cells. Mol Endocrinol 6:927-934
24. 2+ mobilization. J Biol Chem 267:4479-4488
25. Abbaszade IG, Arensburg J, Park CHJ, Kasa Vubu JZ, Orly J, Payne AH 1997 Isolation of a new mouse 3-hydroxysteroid dehydrogenase isoform, 3β-HSD VI, expressed during early pregnancy. Endocrinology 138:1392-1399
26. Murphy LD, Herzog CE, Rudick JB, Fojo AT, Bates SE 1990 Use of the polymerase chain-reaction in the quantitation of mdr-1 gene expression. Biochemistry 29:10351-10356
27. Gray SA, Mannan MA, O'Shaughnessy PJ 1995 Development of cytochrome P450 aromatase mRNA levels and enzyme activity in ovaries of normal and hypogonadal (hpg) mice. J Mol Endocrinol 14:295-301
28. O'Shaughnessy PJ, Gray SA 1995 Gonadotropin-dependent and gonadotropin-independent development of inhibin subunit messenger ribonucleic acid levels in the mouse ovary. Endocrinology 136:2060-2065
29. Sha J, Baker P, O'Shaughnessy PJ 1996 Both reductive forms of 17β-hydroxysteroid dehydrogenase (types 1 and 3) are expressed during development in the mouse testis. Biochem Biophys Res Commun 222:90-94
30. 29a. McDowell IFW, Morris JF, Charlton HM 1982 Characterization of the pituitary gonadotroph cells of hypogonadal (hpg) male mice: comparison with normal mice. J Endocrinol 95:321-330
31. Tepper MA, Roberts JL 1984 Evidence for only one β-luteinizing hormone and no β-chorionic gonadotropin gene in the rat. Endocrinology 115:385-391
32. Carr FE, Chin WW 1985 Absence of detectable chorionic gonadotrophin subunit messenger ribonucleic acid in the rat placenta throughout gestation. Endocrinology 116:1151-1157
33. Benahmed M 1996 Growth factors and cytokines in the testis. In: Comhaire FH (ed) Male Infertility. Clinical Investigation, Cause, Evaluation and Treatment. Chapman and Hall Medical, London, pp 55-95
34. Bitgood MJ, Shen L, McMahon AP 1996 Sertoli cell signaling by Desert hedgehog regulates the male germline. Curr Biol 6:298-304
35. Boujrad N, Ogwuegbu SO, Garnier M, Lee CH, Martin BM, Papadopoulos V 1995 Identification of a stimulator of steroid-hormone synthesis isolated from testis. Science 268:1609-1612
36. Daniello A, Dicosmo A, Dicristo C, Annunziato L, Petrucelli L, Fisher G 1996 Involvement of D-aspartic acid in the synthesis of testosterone in rat testes. Life Sci 59:97-104
37. Kremer H, Kraaij R, Toledo SPA, Post M, Fridman JB, Hayashida CY, van Reen M, Milgrom E, Ropers HH, Mariman E, Themmen APN, Brunner HG 1995 Male pseudohermaphroditism due to a homozygous missense mutation of the luteinizing hormone receptor gene. Nat Genet 9:160-164
38. Word RA, George FW, Wilson JD, Carr BR 1989 Testosterone synthesis and adenylate cyclase activity in the early human fetal testis appear to be independent of human chorionic gonadotropin control. J Clin Endocrinol Metab 69:204-208
39. Weiss J, Axelrod L, Whitcomb RW, Harris PE, Crowley WF, Jameson JL 1992 Hypogonadism caused by n single amino acid substitution in the β-subunit of luteinizing hormone. N Engl J Med 326:179-183
40. Pointis G, Mahoudeau JA 1977 Responsiveness of foetal mouse testis to gonadotrophins at various times during sexual differentiation. J Endocrinol 74:149-150
41. Anakwe OO, Moger WH 1984 Ontogeny of rodent testicular androgen production in response to isoproterenol and luteinizing hormone in vitro. Biol Reprod 30:1142-1152
42. Vergouwen RPFA, Jacobs SGPM, Huiskamp R, Davids JAG, de Rooij DG 1991 Proliferative activity of gonocytes, Sertoli cells and interstitial cells during testicular development in mice. J Reprod Fertil 93:233-243
43. Deleted in proof
44. Greco TL, Payne AH 1994 Ontogeny of expression of the genes for steroidogenic enzymes P450 side chain cleavage, 3β-hydroxysteroid dehydrogenase, P450 17α-hydroxylase C17-20 lyase, and P450 aromatase in fetal mouse gonads. Endocrinology 135:262-268
45. Zhang FP, Hamalainen T, Kaipia A, Pakarinen P, Huhtaniemi I 1994 Ontogeny of luteinizing hormone receptor gene expression in the rat testis. Endocrinology 134:2206-2213