A tissue-specific knockout reveals that Gata1 is not essential for Sertoli cell function in the mouse

Nucleic Acids Research

Volumn 31, Issue 18, 2003, Pages 5405-5412

  Lindeboom, Fokke ^b   Gillemans, Nynke ^b   Karis, Alar ^a   Jaegle, Martine ^b   Meijer, Dies ^b   Grosveld, Frank ^b   Philipsen, Sjaak ^b  

^a UNIVERSITY OF TARTU   (Estonia)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR GATA 1;

ANIMAL CELL; ARTICLE; CELL FUNCTION; CELL SPECIFICITY; CONTROLLED STUDY; FEMALE; GENE DELETION; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; GENE TARGETING; HEDGEHOG; IN VIVO STUDY; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; PROMOTER REGION; SERTOLI CELL; SPERMATOGENESIS; TESTIS DEVELOPMENT; TISSUE SPECIFICITY;

ANIMALS; BINDING SITES; CELLS, CULTURED; DNA-BINDING PROTEINS; ERYTHROID-SPECIFIC DNA-BINDING FACTORS; FEMALE; FERTILITY; GATA1 TRANSCRIPTION FACTOR; GENE EXPRESSION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INTEGRASES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; RECOMBINATION, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SERTOLI CELLS; TESTIS; TRANSCRIPTION FACTORS; VIRAL PROTEINS;

ANIMALIA; ERINACEIDAE;

EID: 0344443361     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkg723     Document Type: Article

References (47)

1. Weiss, M.J. and Orkin, S.H. (1995) GATA transcription factors: key regulators of hematopoiesis. Exp. Hematol., 23, 99-107.
2. Molkentin, J.D. (2000) The zinc finger-containing transcription factors GATA-4, -5 and -6. Ubiquitously expressed regulators of tissue-specific gene expression. J. Biol. Chem., 275, 38949-38952.
3. Hales, D.B. (2001) Editorial: gonadal-specific transcription factors - gata (go) 4 it! Endocrinology, 142, 974-976.
4. Tremblay, J.J. and Viger, R.S. (2001) GATA factors differentially activate multiple gonadal promoters through conserved GATA regulatory elements. Endocrinology, 142, 977-986.
5. Yomogida, K., Ohtani, H., Harigae, H., Ito, E., Nishimune, Y., Engel, J.D. and Yamamoto, M. (1994) Developmental stage- and spermatogenic cycle-specific expression of transcription factor GATA-1 in mouse Sertoli cells. Development, 120, 1759-1766.
6. Ito, E., Toki, T., Ishihara, H., Ohtani, H., Gu, L., Yokoyama, M., Engel, J.D. and Yamamoto, M. (1993) Erythroid transcription factor GATA-1 is abundantly transcribed in mouse testis. Nature, 362, 466-468.
7. Evans, T. and Felsenfeld, G. (1989) The erythroid-specific transcription factor Eryf1: a new finger protein. Cell, 58, 877-885.
8. Martin, D.L.K., Zon, L.I., Mutter, G. and Orkin, S.H. (1990) Expression of an erythroid transcription factor in megakaryocytic and mast cell lineages. Nature, 344, 444-447.
9. Tsai, S., Martin, D.I.K., Zon, L.I., D'Andrea, A.D., Wong, G. and Orkin, S.H. (1989) Cloning the cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells. Nature, 339, 446-451.
10. Romeo, P.H., Prandini, M.H., Joulin, V., Mignotte, V., Prenant, M., Vainchenker, W., Marguerie, G. and Uzan, G. (1990) Megakaryocytic and erythrocytic lineages share specific transcription factors. Nature, 344, 447-449.
11. Zon, L.I., Yamaguchi, Y., Yee, K., Albee, E.A., Kimura, A., Bennett, J.C., Orkin, S.H. and Ackerman, S.J. (1993) Expression of mRNA for the GATA-binding proteins in human eosinophils and basophils: potential role in gene transcription. Blood, 81, 3234-3241.
12. Pevny, L., Simon, M.C., Robertson, E., Klein, W.H., Tsai, S.F., D'Agati, V., Orkin, S.H. and Costantini, F. (1991) Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1. Nature, 349, 257-260.
13. Onodera, K., Yomogida, K., Suwabe, N., Takahashi, S., Muraosa, Y., Hayashi, N., Ito, E., Gu, L., Rassoulzadegan, M., Engel J.D. et al. (1997) Conserved structure, regulatory elements and transcriptional regulation from the GATA-1 gene testis promoter. J. Biochem., 121, 251-263.
14. Watanabe, K., Clarke, T.R., Lane, A.H., Wang, X. and Donahoe, P.K. (2000) Endogenous expression of Mullerian inhibiting substance in early postnatal rat sertoli cells requires multiple steroidogenic factor-1 and GATA-4-binding sites. Proc. Natl Acad. Sci. USA, 97, 1624-1629.
15. Beau, C., Rauch, M., Joulin, V., Jegou, B. and Guerrier, D. (2000) GATA-1 is a potential repressor of anti-Mullerian hormone expression during the establishment of puberty in the mouse. Mol. Reprod. Dev., 56, 124-138.
16. Ketola, I., Rahman, N., Toppari, J., Bielinska, M., Porter-Tinge, S.B., Tapanainen, J.S., Huhtaniemi, I.T., Wilson, D.B. and Heikinheimo, M. (1999) Expression and regulation of transcription factors GATA-4 and GATA-6 in developing mouse testis. Endocrinology, 140, 1470-1480.
17. Nichols, K.E., Crispino, J.D., Poncz, M., White, J.G., Orkin, S.H., Maris, J.M. and Weiss, M.J. (2000) Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1. Nature Genet., 24, 266-270.
18. Behringer, R.R., Cate, R.L., Froelick, G.J., Palmiter, R.D. and Brinster, R.L. (1990) Abnormal sexual development in transgenic mice chronically expressing mullerian inhibiting substance. Nature, 345, 167-170.
19. Freson, K., Devriendt, K., Matthijs, G., Van Hoof, A., De Vos, R., Thys, C., Minner, K., Hoylaerts, M.F., Vermylen, J. and Van Geet, C. (2001) Platelet characteristics in patients with X-linked macrothrombocytopenia because of a novel GATA1 mutation. Blood, 98, 85-92.
20. Mehaffey, M.G., Newton, A.L., Gandhi, M.J., Crossley, M. and Drachman, J.G. (2001) X-linked thrombocytopenia caused by a novel mutation of GATA-1. Blood, 98, 2681-2688.
21. Kim, J.S. and Griswold, M.D. (2001) E217 and GATA-1 are required for the Sertoli cell-specific promoter activity of the follicle-stimulating hormone receptor gene. J. Androl., 22, 629-639.
22. Feng, Z.M. and Chen, C.L. (1994) Negative control of the rat inhibin alpha subunit promoter in MA-10 Leydig tumour cells. J. Mol. Endocrinol., 13, 39-47.
23. Feng, Z.M., Wu, A.Z., Zhang, Z. and Chen, C.L. (2000) GATA-1 and GATA-4 transactivate inhibin/activin beta-B-subunit gene transcription in testicular cells. Mol. Endocrinol., 14, 1820-1835.
24. Krummen, L.A., Toppari, J., Kim, W.H., Morelos, B.S., Ahmad, N., Swerdloff, R.S., Ling, N., Shimasaki, S., Esch, F. and Bhasin, S. (1989) Regulation of testicular inhibin subunit messenger ribonucleic acid levels in vivo: effects of hypophysectomy and selective follicle-stimulating hormone replacement. Endocrinology, 125, 1630-1637.
25. Feng, Z.M., Bardin, C.W. and Chen, C.L. (1989) Characterization and regulation of testicular inhibin beta-subunit mRNA. Mol. Endocrinol., 3, 939-948.
26. Keinan, D., Madigan, M.B., Bardin, C.W. and Chen, C.L. (1989) Expression and regulation of testicular inhibin alpha-subunit gene in vivo and in vitro. Mol. Endocrinol., 3, 29-35.
27. Sauer, B. (1996) Multiplex Cre/lox recombination permits selective site-specific DNA targeting to both a natural and an engineered site in the yeast genome. Nucleic Acids Res., 24, 4608-4613.
28. Bitgood, M.J., Shen, L. and McMahon, A.P. (1996) Sertoli cell signaling by Desert hedgehog regulates the male germline. Curr. Biol., 6, 298-304.
29. Mountford, P., Zevnik, B., Duwel, A., Nichols, J., Li, M., Dani, C., Robertson, M., Chambers, I. and Smith, A. (1994) Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression. Proc. Natl Acad. Sci. USA, 91, 4303-4307.
30. Kalderon, D., Roberts, B.L., Richardson, W.D. and Smith, A.E. (1984) A short amino acid sequence able to specify nuclear location. Cell, 39, 499-509.
31. Soriano, P. (1999) Generalized lacZ expression with the ROSA26 Cre reporter strain. Nature Genet., 21, 70-71.
32. Tewari, R., Gillemans, N., Harper, A., Wijgerde, M., Zafarana, G., Drabek, D., Grosveld, F. and Philipsen, S. (1996) The human beta-globin locus control region confers an early embryonic erythroid-specific expression pattern to a basic promoter driving the bacterial lacZ gene. Development, 122, 3991-3999.
33. Silverman, E., Eimerl, S. and Orly, J. (1999) CCAAT enhancer-binding protein beta and GATA-4 binding regions within the promoter of the steroidogenic acute regulatory protein (StAR) gene are required for transcription in rat ovarian cells. J. Biol. Chem., 274, 17987-17996.
34. Jin, T., Zhang, X., Li, H. and Goss, P.E. (2000) Characterization of a novel silencer element in the human aromatase gene PII promoter. Breast Cancer Res. Treat., 62, 151-159.
35. Weiss, M.J., Keller, G. and Orkin, S.H. (1994) Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells. Genes Dev., 8, 1184-1197.
36. Takahashi, S., Shimizu, R., Suwabe, N., Kuroha, T., Yoh, K., Ohta, J., Nishimura, S., Lim, K.C., Engel, J.D. and Yamamoto, M. (2000) GATA factor transgenes under GATA-1 locus control rescue germline GATA-1 mutant deficiencies. Blood, 96, 910-916.
37. Onodera, K., Takabashi, S., Nishimura, S., Ohta, J., Motohashi, H., Yomogida, K., Hayashi, N., Engel, J.D. and Yamamoto, M. (1997) GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis. Proc. Natl Acad. Sci. USA, 94, 4487-4492.
38. Schwartzbauer, G., Schlesinger, K. and Evans, T. (1992) Interaction of the erythroid transcription factor cGATA-1 with a critical auto-regulatory element. Nucleic Acids Res., 20, 4429-4436.
39. Trainor, C.D., Evans, T. and Felsenfeld, G. (1995) Negative regulation of chicken GATA-1 promoter activity mediated by a hormone response element. Mol. Endocrinol., 9, 1135-1146.
40. Vyas, P., McDevitt, M.A., Cantor, A.B., Katz, S.G., Fujiwara, Y. and Orkin, S.H. (1999) Different sequence requirements for expression in erythroid and megakaryocytic cells within a regulatory element upstream of the GATA-1 gene. Development, 126, 2799-2811.
41. Shivdasani, R.A., Fujiwara, Y., McDevitt, M.A. and Orkin, S.H. (1997) A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development. EMBO J., 16, 3965-3973.
42. Feng, Z.M., Wu, A.Z. and Chen, C.L. (1998) Testicular GATA-1 factor up-regulates the promoter activity of rat inhibin alpha-subunit gene in MA-10 Leydig tumor cells. Mol. Endocrinol., 12, 378-390.
43. Viger, R.S., Mertineit, C., Trasler, J.M. and Nemer, M. (1998) Transcription factor GATA-4 is expressed in a sexually dimorphic pattern during mouse gonadal development and is a potent activator of the Mullerian inhibiting substance promoter. Development, 125, 2665-2675.
44. Tevosian, S.G., Albrecht, K.H., Crispino, J.D., Fujiwara, Y., Eicher, E.M. and Orkin, S.H. (2002) Gonadal differentiation, sex determination and normal Sry expression in mice require direct interaction between transcription partners GATA4 and FOG2. Development, 129, 4627-4634.
45. Liang, Q., De Windt, L.J., Witt, S.A., Kimball, T.R., Markham, B.E. and Molkentin, J.D. (2001) The transcription factors GATA4 and GATA6 regulate cardiomyocyte hypertrophy in vitro and in vivo. J. Biol. Chem., 276, 30245-30253.
46. Bruno, M.D., Korfhagen, T.R., Liu, C., Morrisey, E.E. and Whitsett, J.A. (2000) GATA-6 activates transcription of surfactant protein A. J. Biol. Chem., 275, 1043-1049.
47. Sykes, T.G., Rodaway, A.R., Walmsley, M.E. and Patient, R.K. (1998) Suppression of GATA factor activity causes axis duplication in Xenopus. Development, 125, 4595-4605.