Acetyl-l-carnitine prevents homocysteine-induced suppression of Nrf2/Keap1 mediated antioxidation in human lens epithelial cells

Molecular Medicine Reports

Volumn 12, Issue 1, 2015, Pages 1145-1150

  Yang, Shui Ping ^a   Yang, Xiu Zhen ^a   Cao, Guo Ping ^a  

^a Taizhou People's Hospital   (China)

Author keywords

Acetyl l carnitine; Antioxidant; DNA demethylation; Homocysteine; Human lens epithelial cells; Nuclear factor erythroid 2 related factor 2

Indexed keywords

CATALASE; GLUCOSE REGULATED PROTEIN 78; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; HOMOCYSTEINE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; LEVACECARNINE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; ACETYLCARNITINE; ANTIOXIDANT; GLUTATHIONE; KEAP1 PROTEIN, HUMAN; NFE2L2 PROTEIN, HUMAN; PROTEASOME; SIGNAL PEPTIDE;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL DEATH; CONTROLLED STUDY; DEMETHYLATION; DNA METHYLATION; DRUG EFFICACY; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; LENS EPITHELIUM CELL; OXIDATIVE STRESS; PROMOTER REGION; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CYTOLOGY; DRUG EFFECTS; GENETIC EPIGENESIS; GENETIC TRANSCRIPTION; GENETICS; LENS; METABOLISM; PROTEIN DEGRADATION;

ACETYLCARNITINE; ANIMALS; ANTIOXIDANTS; CATALASE; CELL DEATH; CELL LINE; DNA METHYLATION; ENDOPLASMIC RETICULUM STRESS; EPIGENESIS, GENETIC; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HOMOCYSTEINE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LENS, CRYSTALLINE; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PROMOTER REGIONS, GENETIC; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; TRANSCRIPTION, GENETIC;

EID: 84926620070     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3490     Document Type: Article

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