Low glucose under hypoxic conditions induces unfolded protein response and produces reactive oxygen species in lens epithelial cells

Cell Death and Disease

Volumn 3, Issue 4, 2012, Pages

  Elanchezhian, R ^a   Palsamy, P ^a   Madson, C J ^a   Mulhern, M L ^a   Lynch, D W ^a   Troia, A M ^a   Usukura, J ^b   Shinohara, T ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b NAGOYA UNIVERSITY   (Japan)

Author keywords

Hypoxia; Low glucose; Nrf2; Reactive oxygen species; UPR

Indexed keywords

GLUCOSE; GLUTATHIONE; OXYGEN; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; ANTIOXIDANT;

ANIMAL CELL; APOPTOSIS; ARTICLE; CATARACT; CELL CULTURE; CELL DIFFERENTIATION; CELL FUNCTION; CONTROLLED STUDY; CORTICAL CATARACT; DIABETES MELLITUS; EPITHELIUM CELL; HUMAN; HUMAN CELL; HYPOGLYCEMIA; HYPOXIA; LENS EPITHELIUM; NONHUMAN; PRIORITY JOURNAL; RAT; UNFOLDED PROTEIN RESPONSE; ANIMAL; CELL HYPOXIA; CYTOLOGY; DRUG EFFECT; IMMUNOHISTOCHEMISTRY; ISCHEMIA; LENS; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELL HYPOXIA; CELLS, CULTURED; EPITHELIAL CELLS; GLUCOSE; GLUTATHIONE; HUMANS; IMMUNOHISTOCHEMISTRY; ISCHEMIA; LENS CORTEX, CRYSTALLINE; NF-E2-RELATED FACTOR 2; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; UNFOLDED PROTEIN RESPONSE;

EID: 84862072111     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2012.40     Document Type: Article

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