메뉴 건너뛰기




Volumn 13, Issue 3, 2015, Pages 584-591

P53 mutation directs AURKA overexpression via miR-25 and FBXW7 in prostatic small cell neuroendocrine carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

AURORA A KINASE; FBXW7 ENZYME; MICRORNA; MICRORNA 25; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; AURKA PROTEIN, HUMAN; CELL CYCLE PROTEIN; F BOX PROTEIN; FBXW7 PROTEIN, HUMAN; MIRN25 MICRORNA, HUMAN; PROTEIN P53; TP53 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

EID: 84926471462     PISSN: 15417786     EISSN: 15573125     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-14-0277-T     Document Type: Article
Times cited : (62)

References (38)
  • 1
    • 0024440505 scopus 로고
    • The course of neuroendocrine differentiation in prostatic carcinomas. An immunohistochemical study testing chromogranin A as an 'endocrine marker'
    • Abrahamsson PA, Falkmer S, Falt K, Grimelius L. The course of neuroendocrine differentiation in prostatic carcinomas. An immunohistochemical study testing chromogranin A as an 'endocrine marker'. Pathol Res Pract 1989;185:373-80.
    • (1989) Pathol Res Pract , vol.185 , pp. 373-380
    • Abrahamsson, P.A.1    Falkmer, S.2    Falt, K.3    Grimelius, L.4
  • 3
    • 84862650290 scopus 로고    scopus 로고
    • Pathogenesis of prostatic small cell carcinoma involves the inactivation of the P53 pathway
    • Chen H, Sun Y, Wu C, Magyar CE, Li X, Cheng L, et al. Pathogenesis of prostatic small cell carcinoma involves the inactivation of the P53 pathway. Endocr Relat Cancer 2012;19:321-31.
    • (2012) Endocr Relat Cancer , vol.19 , pp. 321-331
    • Chen, H.1    Sun, Y.2    Wu, C.3    Magyar, C.E.4    Li, X.5    Cheng, L.6
  • 4
    • 84860168795 scopus 로고    scopus 로고
    • Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets
    • Beltran H, Rickman DS, Park K, Chae SS, Sboner A, MacDonald TY, et al. Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets. Cancer Discov 2011;1: 487-95.
    • (2011) Cancer Discov , vol.1 , pp. 487-495
    • Beltran, H.1    Rickman, D.S.2    Park, K.3    Chae, S.S.4    Sboner, A.5    Macdonald, T.Y.6
  • 5
    • 0242690301 scopus 로고    scopus 로고
    • Receptor protein tyrosine phosphatase alpha signaling is involved in androgen depletion-induced neuroendocrine differentiation of androgen- sensitive LNCaP human prostate cancer cells
    • Zhang XQ, Kondrikov D, Yuan TC, Lin FF, Hansen J, Lin MF. Receptor protein tyrosine phosphatase alpha signaling is involved in androgen depletion-induced neuroendocrine differentiation of androgen- sensitive LNCaP human prostate cancer cells. Oncogene 2003;22: 6704-16.
    • (2003) Oncogene , vol.22 , pp. 6704-6716
    • Zhang, X.Q.1    Kondrikov, D.2    Yuan, T.C.3    Lin, F.F.4    Hansen, J.5    Lin, M.F.6
  • 6
    • 79954488451 scopus 로고    scopus 로고
    • Low-dose valproic acid enhances radiosensitivity of prostate cancer through acetylated p53-dependent modulation of mitochondrial membrane potential and apoptosis
    • Chen X, Wong JY, Wong P, Radany EH. Low-dose valproic acid enhances radiosensitivity of prostate cancer through acetylated p53-dependent modulation of mitochondrial membrane potential and apoptosis. Mol Cancer Res 2011;9:448-61.
    • (2011) Mol Cancer Res , vol.9 , pp. 448-461
    • Chen, X.1    Wong, J.Y.2    Wong, P.3    Radany, E.H.4
  • 7
    • 33646739524 scopus 로고    scopus 로고
    • Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor
    • Xin L, Teitell MA, Lawson DA, Kwon A, Mellinghoff IK, Witte ON. Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor. Proc Natl Acad Sci U S A 2006;103:7789-94.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 7789-7794
    • Xin, L.1    Teitell, M.A.2    Lawson, D.A.3    Kwon, A.4    Mellinghoff, I.K.5    Witte, O.N.6
  • 8
    • 34250666701 scopus 로고    scopus 로고
    • Production and purification of lentiviral vectors
    • Tiscornia G, Singer O, Verma IM. Production and purification of lentiviral vectors. Nat Protoc 2006;1:241-5.
    • (2006) Nat Protoc , vol.1 , pp. 241-245
    • Tiscornia, G.1    Singer, O.2    Verma, I.M.3
  • 9
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T))method.Methods 2001;25:402-8.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 10
    • 0028857271 scopus 로고
    • A method for immunohistochemical semiquantitation: Validation for oestrogen receptor in breast carcinomas
    • Detre S, Saclani Jotti G, Dowsett M. A method for immunohistochemical semiquantitation: validation for oestrogen receptor in breast carcinomas. J Clin Pathol 1995;48:876-8.
    • (1995) J Clin Pathol , vol.48 , pp. 876-878
    • Detre, S.1    Saclani Jotti, G.2    Dowsett, M.3
  • 13
    • 80053188655 scopus 로고    scopus 로고
    • PC3 is a cell line characteristic of prostatic small cell carcinoma
    • Tai S, Sun Y, Squires JM, Zhang H, Oh WK, Liang CZ, et al. PC3 is a cell line characteristic of prostatic small cell carcinoma. Prostate 2011;71:1668-79.
    • (2011) Prostate , vol.71 , pp. 1668-1679
    • Tai, S.1    Sun, Y.2    Squires, J.M.3    Zhang, H.4    Oh, W.K.5    Liang, C.Z.6
  • 14
    • 84865083977 scopus 로고    scopus 로고
    • MiR- 25 regulates Wwp2 and Fbxw7 and promotes reprogramming of mouse fibroblast cells to iPSCs
    • Lu D, Davis MP, Abreu-Goodger C, Wang W, Campos LS, Siede J, et al. MiR- 25 regulates Wwp2 and Fbxw7 and promotes reprogramming of mouse fibroblast cells to iPSCs. PLoS One 2012;7:e40938.
    • (2012) PLoS One , vol.7 , pp. e40938
    • Lu, D.1    Davis, M.P.2    Abreu-Goodger, C.3    Wang, W.4    Campos, L.S.5    Siede, J.6
  • 15
    • 57849107571 scopus 로고    scopus 로고
    • Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma
    • Otto T, Horn S, Brockmann M, Eilers U, Schuttrumpf L, Popov N, et al. Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma. Cancer Cell 2009;15:67-78.
    • (2009) Cancer Cell , vol.15 , pp. 67-78
    • Otto, T.1    Horn, S.2    Brockmann, M.3    Eilers, U.4    Schuttrumpf, L.5    Popov, N.6
  • 16
    • 2942614705 scopus 로고    scopus 로고
    • Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7
    • Yada M, Hatakeyama S, Kamura T, Nishiyama M, Tsunematsu R, Imaki H, et al. Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7. EMBO J 2004;23:2116-25.
    • (2004) EMBO J , vol.23 , pp. 2116-2125
    • Yada, M.1    Hatakeyama, S.2    Kamura, T.3    Nishiyama, M.4    Tsunematsu, R.5    Imaki, H.6
  • 17
    • 2942650133 scopus 로고    scopus 로고
    • The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation- dependent c-Myc protein degradation
    • Welcker M, Orian A, Jin J, Grim JE, Harper JW, Eisenman RN, et al. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation- dependent c-Myc protein degradation. Proc Natl Acad Sci U S A 2004;101:9085-90.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 9085-9090
    • Welcker, M.1    Orian, A.2    Jin, J.3    Grim, J.E.4    Harper, J.W.5    Eisenman, R.N.6
  • 18
    • 0035812709 scopus 로고    scopus 로고
    • Phosphorylation-dependent ubiquitination of cyclin e by the SCFFbw7 ubiquitin ligase
    • Koepp DM, Schaefer LK, Ye X, Keyomarsi K, Chu C, Harper JW, et al. Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase. Science 2001;294:173-7.
    • (2001) Science , vol.294 , pp. 173-177
    • Koepp, D.M.1    Schaefer, L.K.2    Ye, X.3    Keyomarsi, K.4    Chu, C.5    Harper, J.W.6
  • 19
    • 0035921849 scopus 로고    scopus 로고
    • Human F-box protein hCdc4 targets cyclin e for proteolysis and is mutated in a breast cancer cell line
    • Strohmaier H, Spruck CH, Kaiser P, Won KA, Sangfelt O, Reed SI. Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line. Nature 2001;413:316-22.
    • (2001) Nature , vol.413 , pp. 316-322
    • Strohmaier, H.1    Spruck, C.H.2    Kaiser, P.3    Won, K.A.4    Sangfelt, O.5    Reed, S.I.6
  • 20
    • 84861189396 scopus 로고    scopus 로고
    • Tumor suppressor functions of FBW7 in cancer development and progression
    • Wang Z, Inuzuka H, Zhong J, Wan L, Fukushima H, Sarkar FH, et al. Tumor suppressor functions of FBW7 in cancer development and progression. FEBS Lett 2012;586:1409-18.
    • (2012) FEBS Lett , vol.586 , pp. 1409-1418
    • Wang, Z.1    Inuzuka, H.2    Zhong, J.3    Wan, L.4    Fukushima, H.5    Sarkar, F.H.6
  • 22
    • 84873048485 scopus 로고    scopus 로고
    • Concurrent AURKA and MYCN gene amplifications are harbingers of lethal treatment-related neuroendocrine prostate cancer
    • Mosquera JM, Beltran H, Park K, MacDonald TY, Robinson BD, Tagawa ST, et al. Concurrent AURKA and MYCN gene amplifications are harbingers of lethal treatment-related neuroendocrine prostate cancer. Neoplasia 2013; 15:1-10.
    • (2013) Neoplasia , vol.15 , pp. 1-10
    • Mosquera, J.M.1    Beltran, H.2    Park, K.3    Macdonald, T.Y.4    Robinson, B.D.5    Tagawa, S.T.6
  • 23
    • 34948901399 scopus 로고    scopus 로고
    • Aurora-A: Themaker and breaker of spindle poles
    • Barr AR, Gergely F. Aurora-A: themaker and breaker of spindle poles. J Cell Sci 2007;120:2987-96.
    • (2007) J Cell Sci , vol.120 , pp. 2987-2996
    • Barr, A.R.1    Gergely, F.2
  • 24
    • 25444485717 scopus 로고    scopus 로고
    • Aurora A activates D-TACCMsps complexes exclusively at centrosomes to stabilize centrosomalmicrotubules
    • Barros TP, Kinoshita K, Hyman AA, Raff JW. Aurora A activates D-TACCMsps complexes exclusively at centrosomes to stabilize centrosomalmicrotubules. J Cell Biol 2005;170:1039-46.
    • (2005) J Cell Biol , vol.170 , pp. 1039-1046
    • Barros, T.P.1    Kinoshita, K.2    Hyman, A.A.3    Raff, J.W.4
  • 25
    • 33845796538 scopus 로고    scopus 로고
    • NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment
    • Mori D, Yano Y, Toyo-oka K, Yoshida N, Yamada M, Muramatsu M, et al. NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment. Mol Cell Biol 2007;27: 352-67.
    • (2007) Mol Cell Biol , vol.27 , pp. 352-367
    • Mori, D.1    Yano, Y.2    Toyo-Oka, K.3    Yoshida, N.4    Yamada, M.5    Muramatsu, M.6
  • 27
    • 0033634850 scopus 로고    scopus 로고
    • Phosphorylation of CPEB by Eg2 mediates the recruitment of CPSF into an active cytoplasmic polyadenylation complex
    • Mendez R, Murthy KG, Ryan K, Manley JL, Richter JD. Phosphorylation of CPEB by Eg2 mediates the recruitment of CPSF into an active cytoplasmic polyadenylation complex. Mol Cell 2000;6:1253-9.
    • (2000) Mol Cell , vol.6 , pp. 1253-1259
    • Mendez, R.1    Murthy, K.G.2    Ryan, K.3    Manley, J.L.4    Richter, J.D.5
  • 29
    • 39849095077 scopus 로고    scopus 로고
    • E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer
    • Petrocca F, Visone R, Onelli MR, Shah MH, Nicoloso MS, de Martino I, et al. E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer. Cancer Cell 2008;13:272-86.
    • (2008) Cancer Cell , vol.13 , pp. 272-286
    • Petrocca, F.1    Visone, R.2    Onelli, M.R.3    Shah, M.H.4    Nicoloso, M.S.5    De Martino, I.6
  • 30
    • 78649719325 scopus 로고    scopus 로고
    • Nikiforova MN. MiRNA expression profiling of lung adenocarcinomas: Correlation with mutational status
    • Dacic S, Kelly L, Shuai Y, Nikiforova MN. miRNA expression profiling of lung adenocarcinomas: correlation with mutational status. Mod Pathol 2010;23:1577-82.
    • (2010) Mod Pathol , vol.23 , pp. 1577-1582
    • Dacic, S.1    Kelly, L.2    Shuai, Y.3
  • 31
    • 77953948708 scopus 로고    scopus 로고
    • Identification of themiR-106b-25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation
    • Poliseno L, Salmena L, Riccardi L, Fornari A, Song MS, Hobbs RM, et al. Identification of themiR-106b-25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation. Sci Signal 2010;3:ra29.
    • (2010) Sci Signal , vol.3 , pp. ra29
    • Poliseno, L.1    Salmena, L.2    Riccardi, L.3    Fornari, A.4    Song, M.S.5    Hobbs, R.M.6
  • 32
    • 84862908319 scopus 로고    scopus 로고
    • MiR-25 regulates apoptosis by targeting Bim in human ovarian cancer
    • Zhang H, Zuo Z, Lu X, Wang L, Wang H, Zhu Z. MiR-25 regulates apoptosis by targeting Bim in human ovarian cancer. Oncol Rep 2012;27:594-8.
    • (2012) Oncol Rep , vol.27 , pp. 594-598
    • Zhang, H.1    Zuo, Z.2    Lu, X.3    Wang, L.4    Wang, H.5    Zhu, Z.6
  • 33
    • 84856366992 scopus 로고    scopus 로고
    • MiR-25 targets TNF-related apoptosis inducing ligand (TRAIL) death receptor-4 and promotes apoptosis resistance in cholangiocarcinoma
    • Razumilava N, Bronk SF, Smoot RL, Fingas CD, Werneburg NW, Roberts LR, et al. miR-25 targets TNF-related apoptosis inducing ligand (TRAIL) death receptor-4 and promotes apoptosis resistance in cholangiocarcinoma. Hepatology 2012;55:465-75.
    • (2012) Hepatology , vol.55 , pp. 465-475
    • Razumilava, N.1    Bronk, S.F.2    Smoot, R.L.3    Fingas, C.D.4    Werneburg, N.W.5    Roberts, L.R.6
  • 35
    • 33745613510 scopus 로고    scopus 로고
    • Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation
    • Fujii Y, Yada M, Nishiyama M, Kamura T, Takahashi H, Tsunematsu R, et al. Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation. Cancer Sci 2006;97:729-36.
    • (2006) Cancer Sci , vol.97 , pp. 729-736
    • Fujii, Y.1    Yada, M.2    Nishiyama, M.3    Kamura, T.4    Takahashi, H.5    Tsunematsu, R.6
  • 36
    • 84879364450 scopus 로고    scopus 로고
    • The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability
    • King B, Trimarchi T, Reavie L, Xu L, Mullenders J, Ntziachristos P, et al. The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability. Cell 2013;153:1552-66.
    • (2013) Cell , vol.153 , pp. 1552-1566
    • King, B.1    Trimarchi, T.2    Reavie, L.3    Xu, L.4    Mullenders, J.5    Ntziachristos, P.6
  • 38
    • 84975685847 scopus 로고    scopus 로고
    • From sequence to molecular pathology, and amechanism driving the neuroendocrine phenotype in prostate cancer
    • Lapuk AV, Wu C, Wyatt AW, McPherson A, McConeghy BJ, Brahmbhatt S, et al. From sequence to molecular pathology, and amechanism driving the neuroendocrine phenotype in prostate cancer. The Journal of pathology 2012;227:286-97.
    • (2012) The Journal of Pathology , vol.227 , pp. 286-297
    • Lapuk, A.V.1    Wu, C.2    Wyatt, A.W.3    McPherson, A.4    McConeghy, B.J.5    Brahmbhatt, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.