Enalapril in infants with single ventricle: Results of a multicenter randomized trial

Circulation

Volumn 122, Issue 4, 2010, Pages 333-340

  Hsu, Daphne T ^a   Zak, Victor ^c   Mahony, Lynn ^d   Sleeper, Lynn A ^c   Atz, Andrew M ^e   Levine, Jami C ^f   Barker, Piers C ^g   Ravishankar, Chitra ^h   McCrindle, Brian W ⁱ   Williams, Richard V ^j   Altmann, Karen ^a   Ghanayem, Nancy S ^k   Margossian, Renee ^f   Chung, Wendy K ^b   Border, William L ^l   Pearson, Gail D ^m   Stylianou, Mario P ^m   Mital, Seema ^a  

^a CHILDREN S HOSPITAL AT MONTEFIORE   (United States)

^b NewYork Presbyterian Hospital   (United States)

^c NEW ENGLAND RESEARCH INSTITUTES   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^f BOSTON CHILDREN S HOSPITAL   (United States)

^g DUKE UNIVERSITY MEDICAL CENTER   (United States)

^h CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

ⁱ HOSPITAL FOR SICK CHILDREN   (Canada)

^j PRIMARY CHILDREN'S MEDICAL CENTER   (United States)

^k Children's Hospital of Wisconsin   (United States)

^l CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^m NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

more..

Author keywords

angiotensin; congenital; heart defects; heart failure; pediatrics; trials

Indexed keywords

BRAIN NATRIURETIC PEPTIDE; ENALAPRIL; PLACEBO;

ARTICLE; BODY GROWTH; BODY HEIGHT; BODY WEIGHT; CARDIOVASCULAR DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; FOLLOW UP; GASTROINTESTINAL SYMPTOM; HEART FAILURE; HEART SINGLE VENTRICLE; HUMAN; INFANT; INFECTION; LUNG DISEASE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ALDOSTERONE; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANTIHYPERTENSIVE AGENTS; DOUBLE-BLIND METHOD; ENALAPRIL; ENDOTHELIUM, VASCULAR; GLOMERULAR FILTRATION RATE; HEART FAILURE; HEART VENTRICLES; HUMANS; INFANT; STROKE VOLUME;

EID: 77955172447     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.109.927988     Document Type: Article

References (28)

1. Steinberger EK, Ferencz C, Loffredo CA. Infants with single ventricle: a population-based epidemiological study. Teratology. 2002;65:106-115.
2. Hehir DA, Dominguez TE, Ballweg JA, Ravishankar C, Marino BS, Bird GL, Nicolson SC, Spray TL, Gaynor JW, Tabbutt S. Risk factors for interstage death after stage 1 reconstruction of hypoplastic left heart syndrome and variants. J Thorac Cardiovasc Surg. 2008;136:94-99.
3. Hannan RL, Ybarra MA, Ojito JW, Alonso FA, Rossi AF, Burke RP. Complex neonatal single ventricle palliation using antegrade cerebral perfusion. Ann Thorac Surg. 2006;82:1278-1284.
4. Connor JA, Gauvreau K, Jenkins KJ. Factors associated with increased resource utilization for congenital heart disease. Pediatrics. 2005;116: 689-695.
5. Cheung YF, Penny DJ, Redington AN. Serial assessment of left ventricular diastolic function after Fontan procedure. Heart. 2000;83:420-424.
6. Gentles TA, Mayer JE, Gauvreau K, Newburger JW, Lock JE, Kupfer-schmid JP, Burnett J, Jonas RA, Castaneda AR, Wernovsky G. Fontan operation in five hundred consecutive patients: factors influencing early and late outcome. J Thoracic Cardiovasc Surg. 1997;114:376-391.
7. Seliem M, Muster AJ, Paul MH, Benson DW. Relation between preop-erative left ventricular muscle mass and outcome of the Fontan procedure in patients with tricuspid atresia. J Am Coll Cardiol. 1989;14:750-755.
8. Cohen MI, Bush DM, Perry RJ, Spray TJ, Moshang T, Wernovsky G, Vetter VL. Somatic growth failure after the Fontan operation. Cardiol Young. 2002;10:447-457.
9. Day RW, Denton DM, Jackson WD. Growth of children with a functionally single ventricle following palliation at moderately increased altitude. Cardiol Young. 2000;10:193-200.
10. Vogt KN, Manlhiot C, Van Arsdell G, Russell JL, Mital S, McCrindle BW. Somatic growth in children with single ventricle physiology impact of physiologic state. J Am Coll Cardiol. 2007;50:1876-1883.
11. Mori Y, Nakazawa M, Tomimatsu H, Momma K. Long term effect of angiotensin-converting enzyme inhibitor in volume overload heart during growth: a controlled pilot study. J Am Coll Cardiol. 2000;36:270-275.
12. Calabro R, Piscane C, Pacileo G, Russo MG. Hemodynamic effects of a single oral dose of enalapril among children with asymptomatic chronic mitral regurgitation. Am J Cardiol. 1999;138:955-961.
13. Shaw NJ, Wilson N, Dickinson DF. Captopril in heart failure secondary to a left to right shunt. Arch Dis Child. 1988;63:360-363.
14. Scammell AM, Arnold R, Wilkinson JL. Captopril in treatment of infant heart failure: a preliminary report. Int J Cardiol. 1987;16:295-301.
15. Frenneaux M, Stewart RAH, Newman CMH, Hallidie-Smith KA. Enalapril for severe heart failure in infancy. Arch Dis Child. 1989;64:219-223.
16. Montigny M, Davignon A, Fouron JC, Biron P, Fournier A, Elie R. Captopril in infants for congestive heart failure secondary to a large ventricular left-to-right shunt. Am J Cardiol. 1989;63:631-633.
17. Seguchi M, Nakazawa M, Momma K. Effect of enalapril on infants and children with congestive heart failure. Cardiol Young. 1992;2:14-19.
18. Mahony L, Sleeper LA, Anderson PA, Gersony WM, McCrindle BW, Minich LL, Newburger JW, Saul JP, Vetter VL, Pearson GD. The Pediatric Heart Network: a primer for the conduct of multicenter studies in children with congenital and acquired heart disease. Pediatr Cardiol. 2006;27:191-198.
19. Hsu DT, Mital S, Ravishankar C, Margossian R, Li JS, Sleeper LA, Williams RV, Levine JC, McCrindle BW, Atz AM, Servedio D, Mahony L. Rationale and design of a trial of angiotensin-converting enzyme inhibition in infants with single ventricle. Am Heart J. 2009;157:37-45.
20. Ross RD, Daniels SR, Schwartz DC, Hannon DW, Shukla R, Kaplan S. Plasma norepinephrine levels in infants and children with congestive heart failure. Am J Cardiol. 1987;59:911-914.
21. Margossian R, Schwartz ML, Prakash A, Wruck L, Colan SD, Atz AM, Bradley TJ, Fogel MA, Hurwitz LM, Marcus E, Powell AJ, Printz BF, Puchalski MD, Rychik J, Shirali G, Williams R, Yoo SJ, Geva T. Comparison of echocardiographic and cardiac magnetic resonance imaging measurements of functional single ventricular volumes, mass, and ejection fraction (from the Pediatric Heart Network Fontan Cross-Sectional Study). Am J Cardiol. 2009;104:419-428.
22. Sluysmans T, Colan SD. Theoretical and empirical derivation of cardiovascular allometric relationships in children. J Appl Physiol. 2005;99: 445-457.
23. Common terminology criteria for adverse events v3.0 (CTCAE). Available at: http://ctep.cancer.gov/protocoldevelopment/electronic-applications/docs/ ctcaev3.pdf. Accessed August 9, 2006.
24. Ohuchi H, Takasugi H, Ohashi H, Yamada O, Watanabe K, Yagihara T, Echigo S. Abnormalities of neurohormonal and cardiac autonomic nervous activities relate poorly to functional status in Fontan patients. Circulation. 2004;110:2601-2608.
25. Shaddy RE, Boucek MM, Hsu DT, Boucek RJ, Canter CE, Mahony L, Ross RD, Pahl E, Blume ED, Dodd DA, Rosenthal DN, Burr J, LaSalle B, Holubkov R, Lukas MA, Tani LY. Carvedilol for children and adolescents with heart failure: a randomized controlled trial. JAMA. 2007; 298:1171-1179.
26. Kogon BE, Ramaswamy V, Todd K, Plattner C, Kirshbom PM, Kanter KR, Simsic J. Feeding difficulty in newborns following congenital heart surgery. Congenit Heart Dis. 2007;2:332-337.
27. Skarakis-Doyle E, Campbell W, Dempsey L. Identification of children with language impairment: investigating the classification of accuracy of the Macarthur-Bates Communicative Development Inventory-III (CDI-III). Am J Speech Lang Pathol. 2009;18:277-288.
28. Bonow RO, Carabello BA, Chatterjee K, de Leon AC Jr, Faxon DP, Freed MD, Gaasch WH, Lytle BW, Nishimura RA, O'Gara PT, O'Rourke RA, Otto CM, Shah PM, Shanewise JS. 2008 Focused update incorporated into the ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease): endorsed by the Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. Circulation. 2008;118:e523-e661.