Abnormal cytoplasmic extensions associated with active αIIbβ3 are probably the cause for macrothrombocytopenia in Glanzmann thrombasthenia-like syndrome

Blood Coagulation and Fibrinolysis

Volumn 26, Issue 3, 2015, Pages 302-308

  Hauschner, Hagit ^a   Mor Cohen, Ronit ^a   Messineo, Stefania ^b   Mansour, Wissam ^a   Seligsohn, Uri ^a   Savoia, Anna ^b,c   Rosenberg, Nurit ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b INSTITUTE FOR MATERNAL AND CHILD HEALTH IRCCS BURLO GAROFOLO   (Italy)

^c UNIVERSITY OF TRIESTE   (Italy)

Author keywords

alpha IIb beta3; alpha v beta 3; Glanzmann thrombasthenia; integrins; platelets; thrombocytopenias

Indexed keywords

ALPHA2 BETA3 INTEGRIN; ALPHA2 INTEGRIN; COMPLEMENTARY DNA; RNA; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR; BETA3 INTEGRIN; FIBRINOGEN; FIBRINOGEN RECEPTOR; HYBRID PROTEIN; ITGA2B PROTEIN, HUMAN; ITGB3 PROTEIN, HUMAN; TUBULIN; VON WILLEBRAND FACTOR;

ANIMAL CELL; ARTICLE; BHK CELL LINE; CELL ADHESION; CONTROLLED STUDY; DNA TRANSFECTION; EXPRESSION VECTOR; FLOW CYTOMETRY; GENE MUTATION; GLANZMANN DISEASE; MEGAKARYOCYTE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; THROMBOCYTOPENIA; THROMBOCYTOPOIESIS; ANIMAL; BLOOD; CELL LINE; CHEMISTRY; CYTOSKELETON; GENE DELETION; GENE VECTOR; GENETICS; HAMSTER; HUMAN; IMMUNOLOGY; MESOCRICETUS; METABOLISM; MICROTUBULE; MISSENSE MUTATION; PATHOLOGY; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; ULTRASTRUCTURE;

ANIMALS; CELL LINE; CRICETINAE; CYTOSKELETON; DNA, COMPLEMENTARY; FIBRINOGEN; GENETIC VECTORS; HUMANS; INTEGRIN ALPHA2; INTEGRIN BETA3; MEGAKARYOCYTES; MESOCRICETUS; MICROTUBULES; MUTATION, MISSENSE; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN CONFORMATION; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SEQUENCE DELETION; THROMBASTHENIA; TUBULIN; VON WILLEBRAND FACTOR;

EID: 84926431073     PISSN: 09575235     EISSN: 14735733     Source Type: Journal    
DOI: 10.1097/MBC.0000000000000241     Document Type: Article

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