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Volumn 7, Issue 4, 2012, Pages

Outside-in signalling generated by a constitutively activated integrin α IIbβ 3 impairs proplatelet formation in human megakaryocytes

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ALPHA2BBETA3 INTEGRIN; CD45 ANTIGEN; FIBRINOGEN; INTEGRIN; SCLEROPROTEIN; UNCLASSIFIED DRUG; FIBRINOGEN RECEPTOR;

EID: 84860015586     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034449     Document Type: Article
Times cited : (57)

References (26)
  • 1
    • 11144356721 scopus 로고    scopus 로고
    • Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis
    • Avecilla ST, Hattori K, Heissig B, Tejada R, Liao F, et al. (2004) Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis. Nat Med 10: 64-71.
    • (2004) Nat Med , vol.10 , pp. 64-71
    • Avecilla, S.T.1    Hattori, K.2    Heissig, B.3    Tejada, R.4    Liao, F.5
  • 2
    • 34648826777 scopus 로고    scopus 로고
    • Dynamic visualization of thrombopoiesis within bone marrow
    • Junt T, Schulze H, Chen Z, Massberg S, Goerge T, et al. (2007) Dynamic visualization of thrombopoiesis within bone marrow. Science 317: 1767-70.
    • (2007) Science , vol.317 , pp. 1767-1770
    • Junt, T.1    Schulze, H.2    Chen, Z.3    Massberg, S.4    Goerge, T.5
  • 4
    • 33748189345 scopus 로고    scopus 로고
    • Regulation of proplatelet formation and platelet release by integrin αIIbβ3
    • Larson MK, Watson SP, (2006) Regulation of proplatelet formation and platelet release by integrin αIIbβ3. Blood 108: 1509-14.
    • (2006) Blood , vol.108 , pp. 1509-1514
    • Larson, M.K.1    Watson, S.P.2
  • 5
    • 54149113333 scopus 로고    scopus 로고
    • Adhesive receptors, extracellular proteins and myosin IIA orchestrate proplatelet formation by human megakaryocytes
    • Balduini A, Pallotta I, Malara A, Lova P, Pecci A, et al. (2008) Adhesive receptors, extracellular proteins and myosin IIA orchestrate proplatelet formation by human megakaryocytes. J Thromb Haemost 6: 1900-7.
    • (2008) J Thromb Haemost , vol.6 , pp. 1900-1907
    • Balduini, A.1    Pallotta, I.2    Malara, A.3    Lova, P.4    Pecci, A.5
  • 6
    • 34247896877 scopus 로고    scopus 로고
    • Glanzmann Thrombasthenia
    • Nurden AT, (2006) Glanzmann Thrombasthenia. Orphanet J Rare Dis 6: 1-10.
    • (2006) Orphanet J Rare Dis , vol.6 , pp. 1-10
    • Nurden, A.T.1
  • 7
    • 66049160883 scopus 로고    scopus 로고
    • Dominant inheritance of a novel integrin β3 mutation associated with a hereditary macrothrombocytopenia and platelet dysfunction in two Italian families
    • Gresele P, Falcinelli E, Giannini S, D'Adamo P, D'Eustacchio A, et al. (2009) Dominant inheritance of a novel integrin β3 mutation associated with a hereditary macrothrombocytopenia and platelet dysfunction in two Italian families. Haematologica 94: 663-9.
    • (2009) Haematologica , vol.94 , pp. 663-669
    • Gresele, P.1    Falcinelli, E.2    Giannini, S.3    D'Adamo, P.4    D'Eustacchio, A.5
  • 8
    • 57749116060 scopus 로고    scopus 로고
    • Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces
    • Zhu J, Luo BH, Xiao T, Zhang C, Nishida N, et al. (2008) Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces. Mol Cell 32: 849-61.
    • (2008) Mol Cell , vol.32 , pp. 849-861
    • Zhu, J.1    Luo, B.H.2    Xiao, T.3    Zhang, C.4    Nishida, N.5
  • 9
    • 0020319589 scopus 로고
    • The origin, development and regulation of megakaryocytes
    • Williams N, Levine RF, (1982) The origin, development and regulation of megakaryocytes. Br J Haematol 52: 173-80.
    • (1982) Br J Haematol , vol.52 , pp. 173-180
    • Williams, N.1    Levine, R.F.2
  • 10
    • 59849107667 scopus 로고    scopus 로고
    • Proplatelet formation in heterozygous Bernard-Soulier syndrome type Bolzano
    • Balduini A, Malara A, Pecci A, Badalucco S, Bozzi V, et al. (2009) Proplatelet formation in heterozygous Bernard-Soulier syndrome type Bolzano. J Thromb Haemost 7: 478-84.
    • (2009) J Thromb Haemost , vol.7 , pp. 478-484
    • Balduini, A.1    Malara, A.2    Pecci, A.3    Badalucco, S.4    Bozzi, V.5
  • 11
    • 67749093040 scopus 로고    scopus 로고
    • Megakaryocytes of patients with MYH9-related thrombocytopenia present an altered proplatelet formation
    • Pecci A, Malara A, Badalucco S, Bozzi V, Torti M, et al. (2009) Megakaryocytes of patients with MYH9-related thrombocytopenia present an altered proplatelet formation. Thromb Haemost 102: 90-6.
    • (2009) Thromb Haemost , vol.102 , pp. 90-96
    • Pecci, A.1    Malara, A.2    Badalucco, S.3    Bozzi, V.4    Torti, M.5
  • 12
    • 34347390082 scopus 로고    scopus 로고
    • The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway
    • Chen Z, Naveiras O, Balduini A, Mammoto A, Conti MA, et al. (2007) The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway. Blood 100: 171-9.
    • (2007) Blood , vol.100 , pp. 171-179
    • Chen, Z.1    Naveiras, O.2    Balduini, A.3    Mammoto, A.4    Conti, M.A.5
  • 13
    • 0034693854 scopus 로고    scopus 로고
    • Focal Adhesion Kinase: a regulator of focal adhesion dynamics and cell movement
    • Parsons JT, Martin KH, Slack JK, Taylor JM, Weed SA, (2000) Focal Adhesion Kinase: a regulator of focal adhesion dynamics and cell movement. Oncogene 19: 5606-13.
    • (2000) Oncogene , vol.19 , pp. 5606-5613
    • Parsons, J.T.1    Martin, K.H.2    Slack, J.K.3    Taylor, J.M.4    Weed, S.A.5
  • 15
    • 54049152026 scopus 로고    scopus 로고
    • The GPIIb/IIIa (integrin áIIbâ3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend
    • Coller BS, Shattil SJ, (2008) The GPIIb/IIIa (integrin áIIbâ3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend. Blood 112: 3011-25.
    • (2008) Blood , vol.112 , pp. 3011-3025
    • Coller, B.S.1    Shattil, S.J.2
  • 16
    • 0025810562 scopus 로고
    • Adhesive Properties of the β3 Integrins: comparison of GP IIb-IIIa and the Vitronectin Receptor Individually Expressed in Human Melanoma Cells
    • Kieffer N, Fitzgerald LA, Wolf D, Cheresh DA, Phillips DR, (1991) Adhesive Properties of the β3 Integrins: comparison of GP IIb-IIIa and the Vitronectin Receptor Individually Expressed in Human Melanoma Cells. The Journal of Cell Biology 113: 451-461.
    • (1991) The Journal of Cell Biology , vol.113 , pp. 451-461
    • Kieffer, N.1    Fitzgerald, L.A.2    Wolf, D.3    Cheresh, D.A.4    Phillips, D.R.5
  • 17
    • 0035989583 scopus 로고    scopus 로고
    • Activation of integrin áIIbâ3 expressed in Chinese hamster ovary cells is required for interaction with solid-phase von Willebrand factor
    • Mekrache M, Legendre P, Kieffer N, Baruch D, (2009) Activation of integrin áIIbâ3 expressed in Chinese hamster ovary cells is required for interaction with solid-phase von Willebrand factor. British Journal of Haematology 119: 1024-1032.
    • (2009) British Journal of Haematology , vol.119 , pp. 1024-1032
    • Mekrache, M.1    Legendre, P.2    Kieffer, N.3    Baruch, D.4
  • 18
    • 1942425169 scopus 로고    scopus 로고
    • Signalling through GP Ib-IX-V activates αIIbβ3 independently of other receptors
    • Kasirer-Friede A, Cozzi MR, Mazzucato M, De Marco L, Ruggeri ZM, j etal, (2004) Signalling through GP Ib-IX-V activates αIIbβ3 independently of other receptors. Blood 103: 3403-3411.
    • (2004) Blood , vol.103 , pp. 3403-3411
    • Kasirer-Friede, A.1    Cozzi, M.R.2    Mazzucato, M.3    De Marco, L.4    Ruggeri, Z.M.5
  • 19
    • 43549096235 scopus 로고    scopus 로고
    • A non-synonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the αIIbβ3 integrin and co-segregates dominantly with abnormal proplatelet formation and macrothrombocytopenia
    • Ghevaert C, Salsmann A, Watkins NA, Schaffner-Reckinger E, Rankin A, et al. (2008) A non-synonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the αIIbβ3 integrin and co-segregates dominantly with abnormal proplatelet formation and macrothrombocytopenia. Blood 111: 3407-14.
    • (2008) Blood , vol.111 , pp. 3407-3414
    • Ghevaert, C.1    Salsmann, A.2    Watkins, N.A.3    Schaffner-Reckinger, E.4    Rankin, A.5
  • 20
    • 79956280665 scopus 로고    scopus 로고
    • Heterozygous ITGA2B R995W mutation inducing constitutive activation of the αIIbβ3 receptor affects proplatelet formation and causes congenital macrothrombocytopenia
    • Kunishima S, Kashiwagi H, Otsu M, Takayama N, Eto K, et al. (2011) Heterozygous ITGA2B R995W mutation inducing constitutive activation of the αIIbβ3 receptor affects proplatelet formation and causes congenital macrothrombocytopenia. Blood 117: 5479-84.
    • (2011) Blood , vol.117 , pp. 5479-5484
    • Kunishima, S.1    Kashiwagi, H.2    Otsu, M.3    Takayama, N.4    Eto, K.5
  • 21
    • 0037092048 scopus 로고    scopus 로고
    • Coordinate interactions of Csk, Src, and Syk kinases with αIIbβ3 initiate integrin signalling to the cytoskeleton
    • Obergfell A, Eto K, Mocsai A, Buensuceso C, Moores SL, et al. (2002) Coordinate interactions of Csk, Src, and Syk kinases with αIIbβ3 initiate integrin signalling to the cytoskeleton. J Cell Biol 157: 265-75.
    • (2002) J Cell Biol , vol.157 , pp. 265-275
    • Obergfell, A.1    Eto, K.2    Mocsai, A.3    Buensuceso, C.4    Moores, S.L.5
  • 22
    • 0033552631 scopus 로고    scopus 로고
    • Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes
    • Italiano JE Jr, Lecine P, Shivdasani RA, Hartwig JH, (1999) Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes. J Cell Biol. 147: 1299-312.
    • (1999) J Cell Biol , vol.147 , pp. 1299-1312
    • Italiano Jr., J.E.1    Lecine, P.2    Shivdasani, R.A.3    Hartwig, J.H.4
  • 23
    • 77956607977 scopus 로고    scopus 로고
    • ADF/n-cofilin-dependent actin turnover determines platelet formation and sizing
    • Bender M, Eckly A, Hartwig JH, Elvers M, Pleines I, et al. (2010) ADF/n-cofilin-dependent actin turnover determines platelet formation and sizing. Blood 116: 1767-75.
    • (2010) Blood , vol.116 , pp. 1767-1775
    • Bender, M.1    Eckly, A.2    Hartwig, J.H.3    Elvers, M.4    Pleines, I.5
  • 24
    • 77950967181 scopus 로고    scopus 로고
    • Abnormal VWF modifies megakaryopoiesis: studies of platelets and megakaryocyte cultures from patients with von Willebrand disease type 2B
    • Nurden P, Gobbi G, Nurden A, Enouf J, Youlyouz-Marfak I, et al. (2010) Abnormal VWF modifies megakaryopoiesis: studies of platelets and megakaryocyte cultures from patients with von Willebrand disease type 2B. Blood 115: 2649-56.
    • (2010) Blood , vol.115 , pp. 2649-2656
    • Nurden, P.1    Gobbi, G.2    Nurden, A.3    Enouf, J.4    Youlyouz-Marfak, I.5
  • 25
    • 33644967859 scopus 로고    scopus 로고
    • Cord blood in vitro expanded CD41 cells: identification of novel components of megakaryocytopoiesis
    • Balduini A, D'Apolito M, Arcelli D, Conti V, Pecci A, et al. (2006) Cord blood in vitro expanded CD41 cells: identification of novel components of megakaryocytopoiesis. J Thromb Haemost 4: 848-60.
    • (2006) J Thromb Haemost , vol.4 , pp. 848-860
    • Balduini, A.1    D'Apolito, M.2    Arcelli, D.3    Conti, V.4    Pecci, A.5


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