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Volumn 28, Issue 2, 2015, Pages 103-109

The utility of rodent models of autism spectrum disorders

Author keywords

Mouse; Social; Translation; Treatment

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; TARGET OF RAPAMYCIN KINASE;

EID: 84926389439     PISSN: 13507540     EISSN: 14736551     Source Type: Journal    
DOI: 10.1097/WCO.0000000000000183     Document Type: Review
Times cited : (21)

References (59)
  • 1
    • 84886418133 scopus 로고    scopus 로고
    • Clinical neurogenetics: Autism spectrum disorders
    • Mehta SQ, Golshani P. Clinical neurogenetics: Autism spectrum disorders. Neurol Clin 2013; 31:951-968.
    • (2013) Neurol Clin , vol.31 , pp. 951-968
    • Mehta, S.Q.1    Golshani, P.2
  • 2
    • 84912144889 scopus 로고    scopus 로고
    • Synaptic, transcriptional and chromatin genes disrupted in autism
    • De Rubeis S, He X, Goldberg AP, et al. Synaptic, transcriptional and chromatin genes disrupted in autism. Nature 2014; 515:209-215.
    • (2014) Nature , vol.515 , pp. 209-215
    • De Rubeis, S.1    He, X.2    Goldberg, A.P.3
  • 3
    • 84912101541 scopus 로고    scopus 로고
    • The contribution of de novo coding mutations to autism spectrum disorder
    • Iossifov I, O'Roak BJ, Sanders SJ, et al. The contribution of de novo coding mutations to autism spectrum disorder. Nature 2014; 515:216-221.
    • (2014) Nature , vol.515 , pp. 216-221
    • Iossifov, I.1    O'Roak, B.J.2    Sanders, S.J.3
  • 4
    • 84893708713 scopus 로고    scopus 로고
    • A de novo convergence of autism genetics and molecular neuroscience
    • Krumm N, O'Roak BJ, Shendure J, Eichler EE. A de novo convergence of autism genetics and molecular neuroscience. Trends Neurosci 2014; 37:95-105.
    • (2014) Trends Neurosci , vol.37 , pp. 95-105
    • Krumm, N.1    O'Roak, B.J.2    Shendure, J.3    Eichler, E.E.4
  • 5
    • 84871448593 scopus 로고    scopus 로고
    • Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders
    • O'Roak BJ, Vives L, Fu W, et al. Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders. Science 2012; 338:1619-1622.
    • (2012) Science , vol.338 , pp. 1619-1622
    • O'Roak, B.J.1    Vives, L.2    Fu, W.3
  • 6
    • 80053540965 scopus 로고    scopus 로고
    • Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits
    • Penagarikano O, Abrahams BS, Herman EI, et al. Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits. Cell 2011; 147:235-246.
    • (2011) Cell , vol.147 , pp. 235-246
    • Penagarikano, O.1    Abrahams, B.S.2    Herman, E.I.3
  • 7
    • 84896732337 scopus 로고    scopus 로고
    • Assessing behavioural and cognitive domains of autism spectrum disorders in rodents: Current status and future perspectives
    • Kas MJ, Glennon JC, Buitelaar J, et al. Assessing behavioural and cognitive domains of autism spectrum disorders in rodents: current status and future perspectives. Psychopharmacology (Berl) 2014; 231:1125-1146.
    • (2014) Psychopharmacology (Berl) , vol.231 , pp. 1125-1146
    • Kas, M.J.1    Glennon, J.C.2    Buitelaar, J.3
  • 8
    • 84912101598 scopus 로고    scopus 로고
    • CRISPR-Cas9 knockin mice for genome editing and cancer modeling
    • Platt RJ, Chen S, Zhou Y, et al. CRISPR-Cas9 knockin mice for genome editing and cancer modeling. Cell 2014; 159:440-455.
    • (2014) Cell , vol.159 , pp. 440-455
    • Platt, R.J.1    Chen, S.2    Zhou, Y.3
  • 9
    • 26444621497 scopus 로고    scopus 로고
    • Millisecond-timescale, genetically targeted optical control of neural activity
    • Boyden ES, Zhang F, Bamberg E, et al. Millisecond-timescale, genetically targeted optical control of neural activity. Nat Neurosci 2005; 8:1263-1268.
    • (2005) Nat Neurosci , vol.8 , pp. 1263-1268
    • Boyden, E.S.1    Zhang, F.2    Bamberg, E.3
  • 10
  • 11
    • 84866403603 scopus 로고    scopus 로고
    • Morphological and functional reversal of phenotypes in a mouse model of Rett syndrome
    • Robinson L, Guy J, McKay L, et al. Morphological and functional reversal of phenotypes in a mouse model of Rett syndrome. Brain 2012; 135:2699-2710.
    • (2012) Brain , vol.135 , pp. 2699-2710
    • Robinson, L.1    Guy, J.2    McKay, L.3
  • 12
    • 77953280825 scopus 로고    scopus 로고
    • Reversibility of functional deficits in experimental models of Rett syndrome
    • Cobb S, Guy J, Bird A. Reversibility of functional deficits in experimental models of Rett syndrome. Biochem Soc Trans 2010; 38:498-506.
    • (2010) Biochem Soc Trans , vol.38 , pp. 498-506
    • Cobb, S.1    Guy, J.2    Bird, A.3
  • 13
    • 33847266846 scopus 로고    scopus 로고
    • Reversal of neurological defects in a mouse model of Rett syndrome
    • Guy J, Gan J, Selfridge J, et al. Reversal of neurological defects in a mouse model of Rett syndrome. Science 2007; 315:1143-1147.
    • (2007) Science , vol.315 , pp. 1143-1147
    • Guy, J.1    Gan, J.2    Selfridge, J.3
  • 14
    • 84904731433 scopus 로고    scopus 로고
    • Neurexin dysfunction in adult neurons results in autistic-like behavior in mice
    • Rabaneda LG, Robles-Lanuza E, Nieto-Gonzalez JL, Scholl FG. Neurexin dysfunction in adult neurons results in autistic-like behavior in mice. Cell Rep 2014; 8:338-346.
    • (2014) Cell Rep , vol.8 , pp. 338-346
    • Rabaneda, L.G.1    Robles-Lanuza, E.2    Nieto-Gonzalez, J.L.3    Scholl, F.G.4
  • 15
    • 57649225085 scopus 로고    scopus 로고
    • Reversing neurodevelopmental disorders in adults
    • Ehninger D, Li W, Fox K, et al. Reversing neurodevelopmental disorders in adults. Neuron 2008; 60:950-960.
    • (2008) Neuron , vol.60 , pp. 950-960
    • Ehninger, D.1    Li, W.2    Fox, K.3
  • 16
    • 58849153257 scopus 로고    scopus 로고
    • Laminar and compartmental regulation of dendritic growth in mature cortex
    • Chow DK, Groszer M, Pribadi M, et al. Laminar and compartmental regulation of dendritic growth in mature cortex. Nat Neurosci 2009; 12:116-118.
    • (2009) Nat Neurosci , vol.12 , pp. 116-118
    • Chow, D.K.1    Groszer, M.2    Pribadi, M.3
  • 17
    • 84865508373 scopus 로고    scopus 로고
    • Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice
    • Tsai PT, Hull C, Chu Y, et al. Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice. Nature 2012; 488:647-651.
    • (2012) Nature , vol.488 , pp. 647-651
    • Tsai, P.T.1    Hull, C.2    Chu, Y.3
  • 18
    • 49149088555 scopus 로고    scopus 로고
    • Reversal of learning deficits in a Tsc2/-mouse model of tuberous sclerosis
    • Ehninger D, Han S, Shilyansky C, et al. Reversal of learning deficits in a Tsc2/-mouse model of tuberous sclerosis. Nat Med 2008; 14:843-848.
    • (2008) Nat Med , vol.14 , pp. 843-848
    • Ehninger, D.1    Han, S.2    Shilyansky, C.3
  • 19
    • 60849109211 scopus 로고    scopus 로고
    • Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice
    • Zhou J, Blundell J, Ogawa S, et al. Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice. J Neurosci 2009; 29:1773-1783.
    • (2009) J Neurosci , vol.29 , pp. 1773-1783
    • Zhou, J.1    Blundell, J.2    Ogawa, S.3
  • 20
    • 84871765155 scopus 로고    scopus 로고
    • Rapamycin reverses impaired social interaction in mouse models of tuberous sclerosis complex
    • Sato A, Kasai S, Kobayashi T, et al. Rapamycin reverses impaired social interaction in mouse models of tuberous sclerosis complex. Nat Commun 2012; 3:1292.
    • (2012) Nat Commun , vol.3 , pp. 1292
    • Sato, A.1    Kasai, S.2    Kobayashi, T.3
  • 21
    • 84873325835 scopus 로고    scopus 로고
    • Behavioural and EEG effects of chronic rapamycin treatment in a mouse model of tuberous sclerosis complex
    • Cambiaghi M, Cursi M, Magri L, et al. Behavioural and EEG effects of chronic rapamycin treatment in a mouse model of tuberous sclerosis complex. Neuropharmacology 2013; 67:1-7.
    • (2013) Neuropharmacology , vol.67 , pp. 1-7
    • Cambiaghi, M.1    Cursi, M.2    Magri, L.3
  • 22
    • 74949102875 scopus 로고    scopus 로고
    • Dysregulation of mTOR signaling in fragile X syndrome
    • Sharma A, Hoeffer CA, Takayasu Y, et al. Dysregulation of mTOR signaling in fragile X syndrome. J Neurosci 2010; 30:694-702.
    • (2010) J Neurosci , vol.30 , pp. 694-702
    • Sharma, A.1    Hoeffer, C.A.2    Takayasu, Y.3
  • 23
    • 84907987626 scopus 로고    scopus 로고
    • Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits
    • Tang G, Gudsnuk K, Kuo SH, et al. Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits. Neuron 2014; 83:1131-1143.
    • (2014) Neuron , vol.83 , pp. 1131-1143
    • Tang, G.1    Gudsnuk, K.2    Kuo, S.H.3
  • 24
    • 84894416065 scopus 로고    scopus 로고
    • Postsynaptic FMRP promotes the pruning of cell-to-cell connections among pyramidal neurons in the L5A neocortical network
    • Patel AB, Loerwald KW, Huber KM, Gibson JR. Postsynaptic FMRP promotes the pruning of cell-to-cell connections among pyramidal neurons in the L5A neocortical network. J Neurosci 2014; 34:3413-3418.
    • (2014) J Neurosci , vol.34 , pp. 3413-3418
    • Patel, A.B.1    Loerwald, K.W.2    Huber, K.M.3    Gibson, J.R.4
  • 25
    • 84896692474 scopus 로고    scopus 로고
    • Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior
    • Zhan Y, Paolicelli RC, Sforazzini F, et al. Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior. Nat Neurosci 2014; 17:400-406.
    • (2014) Nat Neurosci , vol.17 , pp. 400-406
    • Zhan, Y.1    Paolicelli, R.C.2    Sforazzini, F.3
  • 26
    • 84889802587 scopus 로고    scopus 로고
    • Dendritic arborization and spine dynamics are abnormal in the mouse model of MECP2 duplication syndrome
    • Jiang M, Ash RT, Baker SA, et al. Dendritic arborization and spine dynamics are abnormal in the mouse model of MECP2 duplication syndrome. J Neurosci 2013; 33:19518-19533.
    • (2013) J Neurosci , vol.33 , pp. 19518-19533
    • Jiang, M.1    Ash, R.T.2    Baker, S.A.3
  • 27
    • 84923282766 scopus 로고    scopus 로고
    • Cerebellar plasticity and motor learning deficits in a copy-number variation mouse model of autism
    • Piochon C, Kloth AD, Grasselli G, et al. Cerebellar plasticity and motor learning deficits in a copy-number variation mouse model of autism. Nat Commun 2014; 5:5586.
    • (2014) Nat Commun , vol.5 , pp. 5586
    • Piochon, C.1    Kloth, A.D.2    Grasselli, G.3
  • 28
    • 84904004407 scopus 로고    scopus 로고
    • Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors
    • Rothwell PE, Fuccillo MV, Maxeiner S, et al. Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors. Cell 2014; 158:198-212.
    • (2014) Cell , vol.158 , pp. 198-212
    • Rothwell, P.E.1    Fuccillo, M.V.2    Maxeiner, S.3
  • 29
    • 84901286741 scopus 로고    scopus 로고
    • Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11. 2 deletion syndrome
    • Portmann T, YangM, Mao R, et al. Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome. Cell Rep 2014; 7:1077-1092.
    • (2014) Cell Rep , vol.7 , pp. 1077-1092
    • Portmann, T.1    Yangm2    Mao, R.3
  • 30
    • 0036772166 scopus 로고    scopus 로고
    • Cerebellar abnormalities in infants and toddlers with Williams syndrome
    • JonesW, Hesselink J, Courchesne E, et al. Cerebellar abnormalities in infants and toddlers with Williams syndrome. Dev Med Child Neurol 2002; 44:688-694.
    • (2002) Dev Med Child Neurol , vol.44 , pp. 688-694
    • Jonesw1    Hesselink, J.2    Courchesne, E.3
  • 31
    • 0036553726 scopus 로고    scopus 로고
    • Purkinje cell size is reduced in cerebellum of patients with autism
    • Fatemi SH, Halt AR, Realmuto G, et al. Purkinje cell size is reduced in cerebellum of patients with autism. Cell Mol Neurobiol 2002; 22:171-175.
    • (2002) Cell Mol Neurobiol , vol.22 , pp. 171-175
    • Fatemi, S.H.1    Halt, A.R.2    Realmuto, G.3
  • 32
    • 0028049131 scopus 로고
    • Cerebellar hypoplasia and hyperplasia in infantile autism
    • Courchesne E, Saitoh O, Townsend JP, et al. Cerebellar hypoplasia and hyperplasia in infantile autism. Lancet 1994; 343:63-64.
    • (1994) Lancet , vol.343 , pp. 63-64
    • Courchesne, E.1    Saitoh, O.2    Townsend, J.P.3
  • 33
    • 84877344739 scopus 로고    scopus 로고
    • Excitatory/inhibitory synaptic imbalance leads to hippocampal hyperexcitability in mouse models of tuberous sclerosis
    • Bateup HS, Johnson CA, Denefrio CL, et al. Excitatory/inhibitory synaptic imbalance leads to hippocampal hyperexcitability in mouse models of tuberous sclerosis. Neuron 2013; 78:510-522.
    • (2013) Neuron , vol.78 , pp. 510-522
    • Bateup, H.S.1    Johnson, C.A.2    Denefrio, C.L.3
  • 34
    • 84877336575 scopus 로고    scopus 로고
    • Autism-associated neuroligin-3 mutations commonly disrupt tonic endocannabinoid signaling
    • Foldy C, Malenka RC, Sudhof TC. Autism-associated neuroligin-3 mutations commonly disrupt tonic endocannabinoid signaling. Neuron 2013; 78:498-509.
    • (2013) Neuron , vol.78 , pp. 498-509
    • Foldy, C.1    Malenka, R.C.2    Sudhof, T.C.3
  • 35
    • 84891750581 scopus 로고    scopus 로고
    • The developmental switch in GABA polarity is delayed in fragile X mice
    • He Q, Nomura T, Xu J, Contractor A. The developmental switch in GABA polarity is delayed in fragile X mice. J Neurosci 2014; 34:446-450.
    • (2014) J Neurosci , vol.34 , pp. 446-450
    • He, Q.1    Nomura, T.2    Xu, J.3    Contractor, A.4
  • 36
    • 84873282879 scopus 로고    scopus 로고
    • A target cell-specific role for presynaptic Fmr1 in regulating glutamate release onto neocortical fast-spiking inhibitory neurons
    • Patel AB, Hays SA, Bureau I, et al. A target cell-specific role for presynaptic Fmr1 in regulating glutamate release onto neocortical fast-spiking inhibitory neurons. J Neurosci 2013; 33:2593-2604.
    • (2013) J Neurosci , vol.33 , pp. 2593-2604
    • Patel, A.B.1    Hays, S.A.2    Bureau, I.3
  • 38
    • 84907598831 scopus 로고    scopus 로고
    • Sensory integration in mouse insular cortex reflects GABA circuit maturation
    • Gogolla N, Takesian AE, Feng G, et al. Sensory integration in mouse insular cortex reflects GABA circuit maturation. Neuron 2014; 83:894-905.
    • (2014) Neuron , vol.83 , pp. 894-905
    • Gogolla, N.1    Takesian, A.E.2    Feng, G.3
  • 39
    • 84893640636 scopus 로고    scopus 로고
    • Oxytocin-mediated GABA inhibition during delivery attenuates autism pathogenesis in rodent offspring
    • Tyzio R, Nardou R, Ferrari DC, et al. Oxytocin-mediated GABA inhibition during delivery attenuates autism pathogenesis in rodent offspring. Science 2014; 343:675-679.
    • (2014) Science , vol.343 , pp. 675-679
    • Tyzio, R.1    Nardou, R.2    Ferrari, D.C.3
  • 40
    • 84871770774 scopus 로고    scopus 로고
    • A randomised controlled trial of bumetanide in the treatment of autism in children
    • Lemonnier E, Degrez C, Phelep M, et al. A randomised controlled trial of bumetanide in the treatment of autism in children. Transl Psychiatry 2012; 2:e202.
    • (2012) Transl Psychiatry , vol.2 , pp. e202
    • Lemonnier, E.1    Degrez, C.2    Phelep, M.3
  • 41
    • 84875270373 scopus 로고    scopus 로고
    • Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism
    • Takeuchi K, Gertner MJ, Zhou J, et al. Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism. Proc Natl Acad Sci USA 2013; 110:4738-4743.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 4738-4743
    • Takeuchi, K.1    Gertner, M.J.2    Zhou, J.3
  • 42
    • 3042647610 scopus 로고    scopus 로고
    • The mGluR theory of fragile X mental retardation
    • Bear MF, Huber KM, Warren ST. The mGluR theory of fragile X mental retardation. Trends Neurosci 2004; 27:370-377.
    • (2004) Trends Neurosci , vol.27 , pp. 370-377
    • Bear, M.F.1    Huber, K.M.2    Warren, S.T.3
  • 43
    • 0037188502 scopus 로고    scopus 로고
    • Altered synaptic plasticity in a mouse model of fragile X mental retardation
    • Huber KM, Gallagher SM, Warren ST, Bear MF. Altered synaptic plasticity in a mouse model of fragile X mental retardation. Proc Natl Acad Sci USA 2002; 99:7746-7750.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 7746-7750
    • Huber, K.M.1    Gallagher, S.M.2    Warren, S.T.3    Bear, M.F.4
  • 44
    • 84897853518 scopus 로고    scopus 로고
    • Changes in mGlu5 receptordependent synaptic plasticity and coupling to Homer proteins in the hippocampus of Ube3A hemizygous mice modeling Angelman syndrome
    • Pignatelli M, Piccinin S, Molinaro G, et al. Changes in mGlu5 receptordependent synaptic plasticity and coupling to Homer proteins in the hippocampus of Ube3A hemizygous mice modeling Angelman syndrome. J Neurosci 2014; 34:4558-4566.
    • (2014) J Neurosci , vol.34 , pp. 4558-4566
    • Pignatelli, M.1    Piccinin, S.2    Molinaro, G.3
  • 45
    • 33646194363 scopus 로고    scopus 로고
    • Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome
    • Nosyreva ED, Huber KM. Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome. J Neurophysiol 2006; 95:3291-3295.
    • (2006) J Neurophysiol , vol.95 , pp. 3291-3295
    • Nosyreva, E.D.1    Huber, K.M.2
  • 46
    • 84859628864 scopus 로고    scopus 로고
    • Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice
    • Michalon A, Sidorov M, Ballard TM, et al. Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice. Neuron 2012; 74:49-56.
    • (2012) Neuron , vol.74 , pp. 49-56
    • Michalon, A.1    Sidorov, M.2    Ballard, T.M.3
  • 47
    • 84891614268 scopus 로고    scopus 로고
    • Chronic metabotropic glutamate receptor 5 inhibition corrects local alterations of brain activity and improves cognitive performance in fragile X mice
    • Michalon A, Bruns A, Risterucci C, et al. Chronic metabotropic glutamate receptor 5 inhibition corrects local alterations of brain activity and improves cognitive performance in fragile X mice. Biol Psychiatry 2014; 75:189-197.
    • (2014) Biol Psychiatry , vol.75 , pp. 189-197
    • Michalon, A.1    Bruns, A.2    Risterucci, C.3
  • 48
    • 84869861822 scopus 로고    scopus 로고
    • Chronic administration of AFQ056/Mavoglurant restores social behaviour in Fmr1 knockout mice
    • Gantois I, Pop AS, de Esch CE, et al. Chronic administration of AFQ056/Mavoglurant restores social behaviour in Fmr1 knockout mice. Behav. Brain Res 2013; 239:72-79.
    • (2013) Behav. Brain Res , vol.239 , pp. 72-79
    • Gantois, I.1    Pop, A.S.2    De Esch, C.E.3
  • 50
    • 84901359464 scopus 로고    scopus 로고
    • PTEN: A master regulator of neuronal structure, function, and plasticity
    • Garcia-Junco-Clemente P, Golshani P. PTEN: A master regulator of neuronal structure, function, and plasticity. Commun Integr Biol 2014; 7:e28358.
    • (2014) Commun Integr Biol , vol.7 , pp. e28358
    • Garcia-Junco-Clemente, P.1    Golshani, P.2
  • 51
    • 84925225933 scopus 로고    scopus 로고
    • Dendritic channelopathies contribute to neocortical and sensory hyperexcitability in Fmr1(-/y) mice
    • Zhang Y, Bonnan A, Bony G, et al. Dendritic channelopathies contribute to neocortical and sensory hyperexcitability in Fmr1(-/y) mice. Nat Neurosci 2014; 17:1701-1709.
    • (2014) Nat Neurosci , vol.17 , pp. 1701-1709
    • Zhang, Y.1    Bonnan, A.2    Bony, G.3
  • 52
    • 84887302333 scopus 로고    scopus 로고
    • Overexpression of calcium-activated potassium channels underlies cortical dysfunction in a model of PTEN-associated autism
    • Garcia-Junco-Clemente P, Chow DK, Tring E, et al. Overexpression of calcium-activated potassium channels underlies cortical dysfunction in a model of PTEN-associated autism. Proc Natl Acad Sci USA 2013; 110:18297-18302.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 18297-18302
    • Garcia-Junco-Clemente, P.1    Chow, D.K.2    Tring, E.3
  • 53
    • 84908077048 scopus 로고    scopus 로고
    • Antagonistic control of social versus repetitive self-grooming behaviors by separable amygdala neuronal subsets
    • Hong W, Kim DW, Anderson DJ. Antagonistic control of social versus repetitive self-grooming behaviors by separable amygdala neuronal subsets. Cell 2014; 158:1348-1361.
    • (2014) Cell , vol.158 , pp. 1348-1361
    • Hong, W.1    Kim, D.W.2    Anderson, D.J.3
  • 54
    • 84891820788 scopus 로고    scopus 로고
    • Amygdala inputs to the ventral hippocampus bidirectionally modulate social behavior
    • Felix-Ortiz AC, Tye KM. Amygdala inputs to the ventral hippocampus bidirectionally modulate social behavior. J Neurosci 2014; 34:586-595.
    • (2014) J Neurosci , vol.34 , pp. 586-595
    • Felix-Ortiz, A.C.1    Tye, K.M.2
  • 55
    • 84926338514 scopus 로고    scopus 로고
    • Towards a therapy for Angelman syndrome by targeting a long noncoding RNA
    • [Epub ahead of print]
    • Meng L,Ward AJ, Chun S, et al. Towards a therapy for Angelman syndrome by targeting a long noncoding RNA. Nature 2014. [Epub ahead of print]
    • (2014) Nature
    • Meng, L.1    Ward, A.J.2    Chun, S.3
  • 56
    • 84870840594 scopus 로고    scopus 로고
    • Two-photon optogenetic toolbox for fast inhibition, excitation and bistable modulation
    • Prakash R, Yizhar O, Grewe B, et al. Two-photon optogenetic toolbox for fast inhibition, excitation and bistable modulation. Nat Methods 2012; 9:1171-1179.
    • (2012) Nat Methods , vol.9 , pp. 1171-1179
    • Prakash, R.1    Yizhar, O.2    Grewe, B.3
  • 57
    • 84925223053 scopus 로고    scopus 로고
    • Simultaneous cellular-resolution optical perturbation and imaging of place cell firing fields
    • Rickgauer JP, Deisseroth K, Tank DW. Simultaneous cellular-resolution optical perturbation and imaging of place cell firing fields. Nat Neurosci 2014; 17:1816-1824.
    • (2014) Nat Neurosci , vol.17 , pp. 1816-1824
    • Rickgauer, J.P.1    Deisseroth, K.2    Tank, D.W.3
  • 58
    • 84875904735 scopus 로고    scopus 로고
    • Long-term dynamics of CA1 hippocampal place codes
    • Ziv Y, Burns LD, Cocker ED, et al. Long-term dynamics of CA1 hippocampal place codes. Nat Neurosci 2013; 16:264-266.
    • (2013) Nat Neurosci , vol.16 , pp. 264-266
    • Ziv, Y.1    Burns, L.D.2    Cocker, E.D.3
  • 59
    • 84887627330 scopus 로고    scopus 로고
    • SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients
    • Shcheglovitov A, Shcheglovitova O, Yazawa M, et al. SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients. Nature 2013; 503:267-271.
    • (2013) Nature , vol.503 , pp. 267-271
    • Shcheglovitov, A.1    Shcheglovitova, O.2    Yazawa, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.